Re-directing CD4+ T cell responses with the flanking residues of MHC class II-bound peptides: The core is not enough

Frontiers in Immunology

Volumn 4, Issue JUL, 2013, Pages

  Holland, Christopher J ^a   Cole, David K ^a   Godkin, Andrew ^a,b  

^a CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^b UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

Author keywords

Crystal structure; MHC processing; Modified peptide; Peptide flanking residue; Peptide major histocompatibility complex class II; T cell receptor; T cell repertoire; Vaccine

Indexed keywords

CORE PROTEIN; EPITOPE; HEMAGGLUTININ; HLA A ANTIGEN; HLA B ANTIGEN; HLA DM ANTIGEN; HLA DR ANTIGEN; HLA DR1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN BASIC PROTEIN; PEPTIDE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANATOMY; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; BINDING AFFINITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CELLULAR IMMUNITY; CRYSTAL STRUCTURE; HUMAN; IMMUNE RESPONSE; INFLAMMATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOLECULAR INTERACTION; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MODIFICATION; REVIEW;

EID: 84883680651     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00172     Document Type: Review

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