HLA-DM targets the hydrogen bond between the histidine at position β81 and peptide to dissociate HLA-DR-peptide complexes

Nature Immunology

Volumn 8, Issue 1, 2007, Pages 92-100

  Narayan, Kedar ^a   Chou, Chih Ling ^a   Kim, AeRyon ^a   Hartman, Isamu Z ^a   Dalai, Sarat ^b   Khoruzhenko, Stanislav ^b   Sadegh Nasseri, Scheherazade ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; HISTIDINE; HLA DM ANTIGEN; HLA DR ANTIGEN; HLA DR1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE;

AMINO ACID SUBSTITUTION; ANTIGEN PRESENTATION; ARTICLE; BETA CHAIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN CONFORMATION;

ANTIGEN PRESENTATION; HISTIDINE; HLA-D ANTIGENS; HLA-DR ANTIGENS; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MULTIPROTEIN COMPLEXES; PEPTIDES; RECOMBINANT PROTEINS;

EID: 33846952190     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1414     Document Type: Article

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