메뉴 건너뛰기




Volumn 15, Issue S3, 2013, Pages 61-70

Metagenome and metabolism: The tissue microbiota hypothesis

Author keywords

Brain axis; Diabetes; Gut; Inflammation; Obesity; Tissue microbiota

Indexed keywords

BACTERIAL DNA; LEPTIN; MYELOID DIFFERENTIATION FACTOR 88; SHORT CHAIN FATTY ACID; TRANSCRIPTOME;

EID: 84883509271     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.12157     Document Type: Review
Times cited : (109)

References (106)
  • 1
    • 0031720795 scopus 로고    scopus 로고
    • Is type II diabetes mellitus a disease of the innate immune system?
    • Pickup JC, Crook MA. Is type II diabetes mellitus a disease of the innate immune system? Diabetologia 1998; 41: 1241-1248.
    • (1998) Diabetologia , vol.41 , pp. 1241-1248
    • Pickup, J.C.1    Crook, M.A.2
  • 2
    • 46249105273 scopus 로고    scopus 로고
    • Adipose tissue lymphocytes and macrophages in obesity and insulin resistance: makers or markers, and which comes first?
    • Bouloumie A, Casteilla L, Lafontan M. Adipose tissue lymphocytes and macrophages in obesity and insulin resistance: makers or markers, and which comes first? Arterioscler Thromb Vasc Biol 2008; 28: 1211-1213.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1211-1213
    • Bouloumie, A.1    Casteilla, L.2    Lafontan, M.3
  • 3
    • 80052278497 scopus 로고    scopus 로고
    • Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
    • Amar J, Chabo C, Waget A et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol Med 2011; 3: 559-572.
    • (2011) EMBO Mol Med , vol.3 , pp. 559-572
    • Amar, J.1    Chabo, C.2    Waget, A.3
  • 4
    • 0001373971 scopus 로고
    • Archean microfossils showing cell division from the swaziland system of South Africa
    • Knoll AH, Barghoorn ES. Archean microfossils showing cell division from the swaziland system of South Africa. Science 1977; 198: 396-398.
    • (1977) Science , vol.198 , pp. 396-398
    • Knoll, A.H.1    Barghoorn, E.S.2
  • 5
    • 84866546211 scopus 로고    scopus 로고
    • Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
    • Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci 2012; 13: 701-712.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 6
    • 84861978076 scopus 로고    scopus 로고
    • Host-gut microbiota metabolic interactions
    • Nicholson JK, Holmes E, Kinross J et al. Host-gut microbiota metabolic interactions. Science 2012; 336: 1262-1267.
    • (2012) Science , vol.336 , pp. 1262-1267
    • Nicholson, J.K.1    Holmes, E.2    Kinross, J.3
  • 7
    • 0014070709 scopus 로고
    • On the origin of mitosing cells
    • Sagan L. On the origin of mitosing cells. J Theor Biol 1967; 14: 255-274.
    • (1967) J Theor Biol , vol.14 , pp. 255-274
    • Sagan, L.1
  • 8
    • 0034913239 scopus 로고    scopus 로고
    • The origin and early evolution of mitochondria
    • REVIEWS1018
    • Gray MW, Burger G, Lang BF. The origin and early evolution of mitochondria. Genome Biol 2001; 2: REVIEWS1018.
    • (2001) Genome Biol , vol.2
    • Gray, M.W.1    Burger, G.2    Lang, B.F.3
  • 10
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010; 464: 59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 11
    • 84858956036 scopus 로고    scopus 로고
    • Patterns of early gut colonization shape future immune responses of the host
    • Hansen CH, Nielsen DS, Kverka M et al. Patterns of early gut colonization shape future immune responses of the host. PLoS One 2012; 7: e34043.
    • (2012) PLoS One , vol.7
    • Hansen, C.H.1    Nielsen, D.S.2    Kverka, M.3
  • 13
    • 0032956143 scopus 로고    scopus 로고
    • Developmental microbial ecology of the neonatal gastrointestinal tract
    • Mackie RI, Sghir A, Gaskins HR. Developmental microbial ecology of the neonatal gastrointestinal tract. Am J Clin Nutr 1999; 69: 1035S-1045S.
    • (1999) Am J Clin Nutr , vol.69
    • Mackie, R.I.1    Sghir, A.2    Gaskins, H.R.3
  • 15
    • 84860390533 scopus 로고    scopus 로고
    • Programming of host metabolism by the gut microbiota
    • Backhed F. Programming of host metabolism by the gut microbiota. Ann Nutr Metab 2011; 58(Suppl 2): 44-52.
    • (2011) Ann Nutr Metab , vol.58 , Issue.SUPPL 2 , pp. 44-52
    • Backhed, F.1
  • 16
    • 84860216630 scopus 로고    scopus 로고
    • Microbial exposure during early life has persistent effects on natural killer T cell function
    • Olszak T, An D, Zeissig S et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012; 336: 489-493.
    • (2012) Science , vol.336 , pp. 489-493
    • Olszak, T.1    An, D.2    Zeissig, S.3
  • 17
    • 77649190768 scopus 로고    scopus 로고
    • Coordination of tolerogenic immune responses by the commensal microbiota
    • Round JL, O'Connell RM, Mazmanian SK. Coordination of tolerogenic immune responses by the commensal microbiota. J Autoimmun 2010; 34: J220-225.
    • (2010) J Autoimmun , vol.34
    • Round, J.L.1    O'Connell, R.M.2    Mazmanian, S.K.3
  • 18
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 2009; 9: 313-323.
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 19
    • 53349173070 scopus 로고    scopus 로고
    • Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
    • Ivanov II, Frutos Rde L, Manel N et al. Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008; 4: 337-349.
    • (2008) Cell Host Microbe , vol.4 , pp. 337-349
    • Ivanov, I.I.1    Frutos Rde, L.2    Manel, N.3
  • 20
    • 84876414806 scopus 로고    scopus 로고
    • The gut microbiota-masters of host development and physiology
    • Sommer F, Backhed F. The gut microbiota-masters of host development and physiology. Nat Rev Microbiol 2013; 11: 227-238.
    • (2013) Nat Rev Microbiol , vol.11 , pp. 227-238
    • Sommer, F.1    Backhed, F.2
  • 21
    • 84868687011 scopus 로고    scopus 로고
    • Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice
    • Caesar R, Reigstad CS, Backhed HK et al. Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice. Gut 2012; 61: 1701-1707.
    • (2012) Gut , vol.61 , pp. 1701-1707
    • Caesar, R.1    Reigstad, C.S.2    Backhed, H.K.3
  • 22
    • 77957236209 scopus 로고    scopus 로고
    • The immune system and the gut microbiota: friends or foes?
    • Cerf-Bensussan N, Gaboriau-Routhiau V. The immune system and the gut microbiota: friends or foes? Nat Rev Immunol 2010; 10: 735-744.
    • (2010) Nat Rev Immunol , vol.10 , pp. 735-744
    • Cerf-Bensussan, N.1    Gaboriau-Routhiau, V.2
  • 23
    • 84857058546 scopus 로고    scopus 로고
    • Immuno-microbiota cross and talk: the new paradigm of metabolic diseases
    • Burcelin R, Garidou L, Pomie C. Immuno-microbiota cross and talk: the new paradigm of metabolic diseases. Semin Immunol 2012; 24: 67-74.
    • (2012) Semin Immunol , vol.24 , pp. 67-74
    • Burcelin, R.1    Garidou, L.2    Pomie, C.3
  • 24
    • 58749112734 scopus 로고    scopus 로고
    • A core gut microbiome in obese and lean twins
    • Turnbaugh PJ, Hamady M, Yatsunenko T et al. A core gut microbiome in obese and lean twins. Nature 2009; 457: 480-484.
    • (2009) Nature , vol.457 , pp. 480-484
    • Turnbaugh, P.J.1    Hamady, M.2    Yatsunenko, T.3
  • 25
    • 84862141704 scopus 로고    scopus 로고
    • Human gut microbiome viewed across age and geography
    • Yatsunenko T, Rey FE, Manary MJ et al. Human gut microbiome viewed across age and geography. Nature 2012; 486: 222-227.
    • (2012) Nature , vol.486 , pp. 222-227
    • Yatsunenko, T.1    Rey, F.E.2    Manary, M.J.3
  • 26
    • 84875150368 scopus 로고    scopus 로고
    • Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4months
    • Azad MB, Konya T, Maughan H et al. Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4months. CMAJ 2013; 185: 385-394.
    • (2013) CMAJ , vol.185 , pp. 385-394
    • Azad, M.B.1    Konya, T.2    Maughan, H.3
  • 27
    • 84873875156 scopus 로고    scopus 로고
    • Gut microbiomes of Malawian twin pairs discordant for kwashiorkor
    • Smith MI, Yatsunenko T, Manary MJ et al. Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science 2013; 339: 548-554.
    • (2013) Science , vol.339 , pp. 548-554
    • Smith, M.I.1    Yatsunenko, T.2    Manary, M.J.3
  • 29
    • 78650408264 scopus 로고    scopus 로고
    • Diet, gut microbiota and immune responses
    • Maslowski KM, Mackay CR. Diet, gut microbiota and immune responses. Nat Immunol 2011; 121: 5-9.
    • (2011) Nat Immunol , vol.121 , pp. 5-9
    • Maslowski, K.M.1    Mackay, C.R.2
  • 30
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani PD, Bibiloni R, Knauf C et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008; 57: 1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3
  • 31
    • 46749098265 scopus 로고    scopus 로고
    • Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice
    • Membrez M, Blancher F, Jaquet M et al. Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. FASEB J 2008; 22: 2416-2426.
    • (2008) FASEB J , vol.22 , pp. 2416-2426
    • Membrez, M.1    Blancher, F.2    Jaquet, M.3
  • 32
    • 33644757817 scopus 로고    scopus 로고
    • Natural antibiotics and insulin sensitivity: the role of bactericidal/permeability-increasing protein
    • Gubern C, Lopez-Bermejo A, Biarnes J, Vendrell J, Ricart W, Fernandez-Real JM. Natural antibiotics and insulin sensitivity: the role of bactericidal/permeability-increasing protein. Diabetes 2006; 55: 216-224.
    • (2006) Diabetes , vol.55 , pp. 216-224
    • Gubern, C.1    Lopez-Bermejo, A.2    Biarnes, J.3    Vendrell, J.4    Ricart, W.5    Fernandez-Real, J.M.6
  • 33
    • 84874357602 scopus 로고    scopus 로고
    • Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
    • Markle JG, Frank DN, Mortin-Toth S et al. Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. Science 2013; 339: 1084-1088.
    • (2013) Science , vol.339 , pp. 1084-1088
    • Markle, J.G.1    Frank, D.N.2    Mortin-Toth, S.3
  • 35
    • 79952757721 scopus 로고    scopus 로고
    • Composition, variability, and temporal stability of the intestinal microbiota of the elderly
    • Claesson MJ, Cusack S, O'Sullivan O et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A 2011; 108(Suppl 1): 4586-4591.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.SUPPL 1 , pp. 4586-4591
    • Claesson, M.J.1    Cusack, S.2    O'Sullivan, O.3
  • 36
    • 84864722033 scopus 로고    scopus 로고
    • Gut microbiota composition correlates with diet and health in the elderly
    • Claesson MJ, Jeffery IB, Conde S et al. Gut microbiota composition correlates with diet and health in the elderly. Nature 2012; 488: 178-184.
    • (2012) Nature , vol.488 , pp. 178-184
    • Claesson, M.J.1    Jeffery, I.B.2    Conde, S.3
  • 37
    • 84874593878 scopus 로고    scopus 로고
    • Metabolic signatures of extreme longevity in northern italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism
    • Collino S, Montoliu I, Martin FP et al. Metabolic signatures of extreme longevity in northern italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism. PLoS One 2013; 8: e56564.
    • (2013) PLoS One , vol.8
    • Collino, S.1    Montoliu, I.2    Martin, F.P.3
  • 38
    • 84870210992 scopus 로고    scopus 로고
    • Role of the gut microbiota in age-related chronic inflammation
    • Rehman T. Role of the gut microbiota in age-related chronic inflammation. Endocr Metabol Immune Dis DrugTarg 2012; 12: 361-367.
    • (2012) Endocr Metabol Immune Dis DrugTarg , vol.12 , pp. 361-367
    • Rehman, T.1
  • 39
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed F, Ding H, Wang T et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 2004; 101: 15718-15723.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15718-15723
    • Backhed, F.1    Ding, H.2    Wang, T.3
  • 42
    • 33845901507 scopus 로고    scopus 로고
    • Human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Human gut microbes associated with obesity. Nature 2006; 444: 1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 44
    • 84857729398 scopus 로고    scopus 로고
    • Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
    • Serino M, Luche E, Gres S et al. Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut 2012; 61: 543-553.
    • (2012) Gut , vol.61 , pp. 543-553
    • Serino, M.1    Luche, E.2    Gres, S.3
  • 45
    • 77953650911 scopus 로고    scopus 로고
    • Molecular characterisation of the faecal microbiota in patients with type II diabetes
    • Wu X, Ma C, Han L et al. Molecular characterisation of the faecal microbiota in patients with type II diabetes. Curr Microbiol 2010; 61: 69-78.
    • (2010) Curr Microbiol , vol.61 , pp. 69-78
    • Wu, X.1    Ma, C.2    Han, L.3
  • 46
    • 77949393654 scopus 로고    scopus 로고
    • Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults
    • Larsen N, Vogensen FK, van den Berg FW et al. Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults. PLoS One 2010; 5: e9085.
    • (2010) PLoS One , vol.5
    • Larsen, N.1    Vogensen, F.K.2    van den Berg, F.W.3
  • 47
    • 84885421002 scopus 로고    scopus 로고
    • Serino M, Fernandez-Real JM, Fuentes EG et al. The gut microbiota profile is associated with insulin action in humans. Acta Diabetol. DOI:10.1007/s00592-012-0410-5.
    • Serino M, Fernandez-Real JM, Fuentes EG et al. The gut microbiota profile is associated with insulin action in humans. Acta Diabetol. 2012; DOI:10.1007/s00592-012-0410-5.
    • (2012)
  • 48
    • 77649125721 scopus 로고    scopus 로고
    • Gut microbiota as a regulator of energy homeostasis and ectopic fat deposition: mechanisms and implications for metabolic disorders
    • Musso G, Gambino R, Cassader M. Gut microbiota as a regulator of energy homeostasis and ectopic fat deposition: mechanisms and implications for metabolic disorders. Curr Opin Lipidol 2010; 21: 76-83.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 76-83
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 49
    • 78649908827 scopus 로고    scopus 로고
    • The role of the gut microbiota in nonalcoholic fatty liver disease
    • Abu-Shanab A, Quigley EM. The role of the gut microbiota in nonalcoholic fatty liver disease. Nat Rev Gastronterol Hepatol 2010; 7: 691-701.
    • (2010) Nat Rev Gastronterol Hepatol , vol.7 , pp. 691-701
    • Abu-Shanab, A.1    Quigley, E.M.2
  • 50
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
    • Henao-Mejia J, Elinav E et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012; 482: 179-185.
    • (2012) Nature , vol.482 , pp. 179-185
    • Henao-Mejia, J.1    Elinav, E.2
  • 51
    • 84873296091 scopus 로고    scopus 로고
    • Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH
    • Zhu L, Baker SS, Gill C et al. Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH. Hepatology 2013; 57: 601-609.
    • (2013) Hepatology , vol.57 , pp. 601-609
    • Zhu, L.1    Baker, S.S.2    Gill, C.3
  • 53
    • 84867074831 scopus 로고    scopus 로고
    • A metagenome-wide association study of gut microbiota in type 2 diabetes
    • Qin J, Li Y, Cai Z et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012; 490: 55-60.
    • (2012) Nature , vol.490 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3
  • 55
    • 0031007065 scopus 로고    scopus 로고
    • The AMP-activated protein kinase-fuel gauge of the mammalian cell?
    • Hardie DG, Carling D. The AMP-activated protein kinase-fuel gauge of the mammalian cell? Eur J Biochem 1997; 246: 259-273.
    • (1997) Eur J Biochem , vol.246 , pp. 259-273
    • Hardie, D.G.1    Carling, D.2
  • 56
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 58
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M, Herrero L, Cipolletta D et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15: 930-939.
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 59
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S, Manabe I, Nagasaki M et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15: 914-920.
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 60
    • 70349232891 scopus 로고    scopus 로고
    • Obesity predisposes to Th17 bias
    • Winer S, Paltser G, Chan Y et al. Obesity predisposes to Th17 bias. Eur J Immunol 2009; 39: 2629-2635.
    • (2009) Eur J Immunol , vol.39 , pp. 2629-2635
    • Winer, S.1    Paltser, G.2    Chan, Y.3
  • 61
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 1996; 271: 665-668.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 63
    • 31044456529 scopus 로고    scopus 로고
    • CCR2 modulates inflammatory and metabolic effects of high-fat feeding
    • Weisberg SP, Hunter D, Huber R et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 2006; 1161: 115-124.
    • (2006) J Clin Invest , vol.1161 , pp. 115-124
    • Weisberg, S.P.1    Hunter, D.2    Huber, R.3
  • 65
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani PD, Amar J, Iglesias MA et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007; 56: 1761-1772.
    • (2007) Diabetes , vol.56 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3
  • 66
    • 43549107065 scopus 로고    scopus 로고
    • Energy intake is associated with endotoxemia in apparently healthy men
    • Amar J, Burcelin R, Ruidavets JB et al. Energy intake is associated with endotoxemia in apparently healthy men. Am J Clin Nutr 2008; 87: 1219-1223.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1219-1223
    • Amar, J.1    Burcelin, R.2    Ruidavets, J.B.3
  • 67
    • 78649978620 scopus 로고    scopus 로고
    • Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation
    • Laugerette F, Vors C, Geloen A et al. Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation. J Nutr Biochem 2011; 22: 53-59.
    • (2011) J Nutr Biochem , vol.22 , pp. 53-59
    • Laugerette, F.1    Vors, C.2    Geloen, A.3
  • 70
    • 33646682882 scopus 로고    scopus 로고
    • Beneficial effects of ApoA-I on LPS-induced acute lung injury and endotoxemia in mice
    • Yan YJ, Li Y, Lou B, Wu MP. Beneficial effects of ApoA-I on LPS-induced acute lung injury and endotoxemia in mice. Life Sci 2006; 79: 210-215.
    • (2006) Life Sci , vol.79 , pp. 210-215
    • Yan, Y.J.1    Li, Y.2    Lou, B.3    Wu, M.P.4
  • 72
    • 76749171211 scopus 로고    scopus 로고
    • Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance
    • Moreno-Navarrete JM, Manco M, Ibanez J et al. Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance. Int J Obes (Lond) 2010; 34: 240-249.
    • (2010) Int J Obes (Lond) , vol.34 , pp. 240-249
    • Moreno-Navarrete, J.M.1    Manco, M.2    Ibanez, J.3
  • 73
    • 84856009496 scopus 로고    scopus 로고
    • Bacterial endotoxin activity in human serum is associated with dyslipidemia, insulin resistance, obesity, and chronic inflammation
    • Lassenius MI, Pietilainen KH, Kaartinen K et al. Bacterial endotoxin activity in human serum is associated with dyslipidemia, insulin resistance, obesity, and chronic inflammation. Diab Care 2011; 34: 1809-1815.
    • (2011) Diab Care , vol.34 , pp. 1809-1815
    • Lassenius, M.I.1    Pietilainen, K.H.2    Kaartinen, K.3
  • 74
    • 80054850343 scopus 로고    scopus 로고
    • Metabolic alterations in adipose tissue during the early phase of experimental endotoxemia in humans
    • Wellhoener P, Vietheer A, Sayk F, Schaaf B, Lehnert H, Dodt C. Metabolic alterations in adipose tissue during the early phase of experimental endotoxemia in humans. Horm Metab Res 2011; 43: 754-759.
    • (2011) Horm Metab Res , vol.43 , pp. 754-759
    • Wellhoener, P.1    Vietheer, A.2    Sayk, F.3    Schaaf, B.4    Lehnert, H.5    Dodt, C.6
  • 75
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh P, Ridaura V, Faith J, Rey F, Knight R, Gordon J. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Trans Med 2009; 1: 6-14.
    • (2009) Sci Trans Med , vol.1 , pp. 6-14
    • Turnbaugh, P.1    Ridaura, V.2    Faith, J.3    Rey, F.4    Knight, R.5    Gordon, J.6
  • 76
    • 84871860548 scopus 로고    scopus 로고
    • Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia
    • Moreira AP, Texeira TF, Ferreira AB, Peluzio Mdo C, Alfenas RC. Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia. Br J Nutr 2012; 108: 801-809.
    • (2012) Br J Nutr , vol.108 , pp. 801-809
    • Moreira, A.P.1    Texeira, T.F.2    Ferreira, A.B.3    Peluzio Mdo, C.4    Alfenas, R.C.5
  • 77
    • 84855174006 scopus 로고    scopus 로고
    • Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice
    • Caricilli AM, Picardi PK, de Abreu LL et al. Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice. PLoS Biol 2011; 9: e1001212.
    • (2011) PLoS Biol , vol.9
    • Caricilli, A.M.1    Picardi, P.K.2    de Abreu, L.L.3
  • 78
    • 84867616398 scopus 로고    scopus 로고
    • High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
    • Kim KA, Gu W, Lee IA, Joh EH, Kim DH. High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway. PLoS One 2012; 7: e47713.
    • (2012) PLoS One , vol.7
    • Kim, K.A.1    Gu, W.2    Lee, I.A.3    Joh, E.H.4    Kim, D.H.5
  • 79
    • 77955492173 scopus 로고    scopus 로고
    • Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
    • Ehses JA, Meier DT, Wueest S et al. Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia 2010; 53: 1795-1806.
    • (2010) Diabetologia , vol.53 , pp. 1795-1806
    • Ehses, J.A.1    Meier, D.T.2    Wueest, S.3
  • 80
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
    • Vijay-Kumar M, Aitken JD, Carvalho FA et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010; 328: 228-231.
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1    Aitken, J.D.2    Carvalho, F.A.3
  • 81
    • 78649605448 scopus 로고    scopus 로고
    • TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin
    • Vijay-Kumar M, Carvalho FA, Aitken JD, Fifadara NH, Gewirtz AT. TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. Eur J Immunol 2010; 40: 3528-3534.
    • (2010) Eur J Immunol , vol.40 , pp. 3528-3534
    • Vijay-Kumar, M.1    Carvalho, F.A.2    Aitken, J.D.3    Fifadara, N.H.4    Gewirtz, A.T.5
  • 82
    • 65549131061 scopus 로고    scopus 로고
    • Bacterial endotoxin stimulates adipose lipolysis via toll-like receptor 4 and extracellular signal-regulated kinase pathway
    • Zu L, He J, Jiang H, Xu C, Pu S, Xu G. Bacterial endotoxin stimulates adipose lipolysis via toll-like receptor 4 and extracellular signal-regulated kinase pathway. J Biol Chem 2009; 284: 5915-5926.
    • (2009) J Biol Chem , vol.284 , pp. 5915-5926
    • Zu, L.1    He, J.2    Jiang, H.3    Xu, C.4    Pu, S.5    Xu, G.6
  • 83
    • 33846302361 scopus 로고    scopus 로고
    • Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation
    • Suganami T, Mieda T, Itoh M, Shimoda Y, Kamei Y, Ogawa Y. Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. Biochem Biophys Res Commun 2007; 354: 45-49.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 45-49
    • Suganami, T.1    Mieda, T.2    Itoh, M.3    Shimoda, Y.4    Kamei, Y.5    Ogawa, Y.6
  • 85
    • 34247884376 scopus 로고    scopus 로고
    • C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
    • Poggi M, Bastelica D, Gual P et al. C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 2007; 50: 1267-1276.
    • (2007) Diabetologia , vol.50 , pp. 1267-1276
    • Poggi, M.1    Bastelica, D.2    Gual, P.3
  • 86
    • 33745187112 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes
    • Song MJ, Kim KH, Yoon JM, Kim JB. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 2006; 346: 739-745.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 739-745
    • Song, M.J.1    Kim, K.H.2    Yoon, J.M.3    Kim, J.B.4
  • 87
    • 84878331136 scopus 로고    scopus 로고
    • Purohit J, Hu P, Burke SJ, Collier JJ, Chen J, Zhao L. The effects of NOD activation on adipocyte differentiation. Obesity
    • Purohit J, Hu P, Burke SJ, Collier JJ, Chen J, Zhao L. The effects of NOD activation on adipocyte differentiation. Obesity 2013; 21: 737-747.
    • (2013) , vol.21 , pp. 737-747
  • 88
    • 80052901762 scopus 로고    scopus 로고
    • NOD1 activators link innate immunity to insulin resistance
    • Schertzer JD, Tamrakar AK, Magalhaes JG et al. NOD1 activators link innate immunity to insulin resistance. Diabetes 2011; 60: 2206-2215.
    • (2011) Diabetes , vol.60 , pp. 2206-2215
    • Schertzer, J.D.1    Tamrakar, A.K.2    Magalhaes, J.G.3
  • 89
    • 65249099918 scopus 로고    scopus 로고
    • Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
    • Cani PD, Possemiers S, Van de Wiele T et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 2009; 58: 1091-1103.
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2    Van de Wiele, T.3
  • 90
    • 0036104085 scopus 로고    scopus 로고
    • Host-pathogen interactions: the seduction of molecular cross talk
    • III2-III8
    • Sansonetti P. Host-pathogen interactions: the seduction of molecular cross talk. Gut 2002; 50(Suppl 3): III2-III8.
    • (2002) Gut , vol.50 , Issue.SUPPL 3
    • Sansonetti, P.1
  • 91
    • 84873722823 scopus 로고    scopus 로고
    • Modulation of intestinal barrier by intestinal microbiota: pathological and therapeutic implications
    • Natividad JM, Verdu EF. Modulation of intestinal barrier by intestinal microbiota: pathological and therapeutic implications. Pharm Res 2013; 69: 42-51.
    • (2013) Pharm Res , vol.69 , pp. 42-51
    • Natividad, J.M.1    Verdu, E.F.2
  • 92
    • 84874410778 scopus 로고    scopus 로고
    • Intestinal dendritic cells: their role in intestinal inflammation, manipulation by the gut microbiota and differences between mice and men
    • Mann ER, Landy JD, Bernardo D et al. Intestinal dendritic cells: their role in intestinal inflammation, manipulation by the gut microbiota and differences between mice and men. Immunol Lett 2013; 150: 30-40.
    • (2013) Immunol Lett , vol.150 , pp. 30-40
    • Mann, E.R.1    Landy, J.D.2    Bernardo, D.3
  • 93
    • 84877145046 scopus 로고    scopus 로고
    • Gut-brain axis: how the microbiome influences anxiety and depression
    • Foster JA, McVey Neufeld KA. Gut-brain axis: how the microbiome influences anxiety and depression. Trends Neurosci 2013; 36: 305-312.
    • (2013) Trends Neurosci , vol.36 , pp. 305-312
    • Foster, J.A.1    McVey Neufeld, K.A.2
  • 94
    • 84865594311 scopus 로고    scopus 로고
    • Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in the gut of Drosophila melanogaster
    • Pezzulo AA, Hornick EE, Rector MV et al. Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in the gut of Drosophila melanogaster. PLoS One 2012; 7: e43777.
    • (2012) PLoS One , vol.7
    • Pezzulo, A.A.1    Hornick, E.E.2    Rector, M.V.3
  • 97
    • 77958536355 scopus 로고    scopus 로고
    • Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice
    • Hosoi T, Yokoyama S, Matsuo S, Akira S, Ozawa K. Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. PLoS One 2010; 5: e12537.
    • (2010) PLoS One , vol.5
    • Hosoi, T.1    Yokoyama, S.2    Matsuo, S.3    Akira, S.4    Ozawa, K.5
  • 98
    • 34249697436 scopus 로고    scopus 로고
    • Role of leptin in immunity
    • Lam QL, Lu L. Role of leptin in immunity. Cell Mol Immunol 2007; 4: 1-13.
    • (2007) Cell Mol Immunol , vol.4 , pp. 1-13
    • Lam, Q.L.1    Lu, L.2
  • 99
    • 82455171885 scopus 로고    scopus 로고
    • Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept
    • Amar J, Serino M, Lange C, Chabo C et al. Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept. Diabetologia 2011; 54: 3055-3061.
    • (2011) Diabetologia , vol.54 , pp. 3055-3061
    • Amar, J.1    Serino, M.2    Lange, C.3    Chabo, C.4
  • 100
    • 84872871160 scopus 로고    scopus 로고
    • Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: the d.e.s.I.R. Study
    • Amar J, Lange C, Payros G et al. Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: the d.e.s.I.R. Study. PLoS One 2013; 8: e54461.
    • (2013) PLoS One , vol.8
    • Amar, J.1    Lange, C.2    Payros, G.3
  • 101
    • 77956310020 scopus 로고    scopus 로고
    • Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism
    • Caesar R, Fak F, Backhed F. Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism. J Intern Med 2010; 268: 320-328.
    • (2010) J Intern Med , vol.268 , pp. 320-328
    • Caesar, R.1    Fak, F.2    Backhed, F.3
  • 102
    • 79952758083 scopus 로고    scopus 로고
    • Human oral, gut, and plaque microbiota in patients with atherosclerosis
    • Koren O, Spor A, Felin J et al. Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proc Natl Acad Sci U S A 2011; 108(Suppl 1): 4592-4598.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.SUPPL 1 , pp. 4592-4598
    • Koren, O.1    Spor, A.2    Felin, J.3
  • 103
    • 84868312808 scopus 로고    scopus 로고
    • High-fat diet induces periodontitis in mice through lipopolysaccharides receptor signaling: protective action of estrogens
    • Blasco-Baque V, Serino M, Vergnes JN et al. High-fat diet induces periodontitis in mice through lipopolysaccharides receptor signaling: protective action of estrogens. PLoS One 2012; 7: e48220.
    • (2012) PLoS One , vol.7
    • Blasco-Baque, V.1    Serino, M.2    Vergnes, J.N.3
  • 104
    • 84864270714 scopus 로고    scopus 로고
    • ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
    • Hashimoto T, Perlot T, Rehman A et al. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature 2012; 487: 477-481.
    • (2012) Nature , vol.487 , pp. 477-481
    • Hashimoto, T.1    Perlot, T.2    Rehman, A.3
  • 105
    • 80054059835 scopus 로고    scopus 로고
    • Enteric microbiome metabolites correlate with response to simvastatin treatment
    • Kaddurah-Daouk R, Baillie RA, Zhu H et al. Enteric microbiome metabolites correlate with response to simvastatin treatment. PLoS One 2011; 6: e25482.
    • (2011) PLoS One , vol.6
    • Kaddurah-Daouk, R.1    Baillie, R.A.2    Zhu, H.3
  • 106
    • 84873342775 scopus 로고    scopus 로고
    • Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
    • Sayin SI, Wahlstrom A, Felin J et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab 2013; 17: 225-235.
    • (2013) Cell Metab , vol.17 , pp. 225-235
    • Sayin, S.I.1    Wahlstrom, A.2    Felin, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.