The effects of NOD activation on adipocyte differentiation

Obesity

Volumn 21, Issue 4, 2013, Pages 737-747

  Purohit, Jaanki S ^a   Hu, Pan ^a   Burke, Susan J ^a   Collier, J Jason ^a   Chen, Jiangang ^a   Zhao, Ling ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CCAAT ENHANCER BINDING PROTEIN ALPHA; FATTY ACID BINDING PROTEIN 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TOLL LIKE RECEPTOR;

ADIPOCYTE; ADULT STEM CELL; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CHRONIC INFLAMMATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; GENE EXPRESSION; IMMUNE RESPONSE; INFLAMMATION; LIPID STORAGE; MOUSE; NONHUMAN; OBESITY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

3T3-L1 CELLS; ADIPOCYTES; ADIPONECTIN; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; FATTY ACID-BINDING PROTEINS; GENE EXPRESSION; HUMANS; LEPTIN; LIPOPOLYSACCHARIDES; MICE; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; PPAR GAMMA; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878331136     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.20275     Document Type: Article

References (40)

1. Gregoire FM, Smas CM, Sul HS,. Understanding adipocyte differentiation. Physiol Rev 1998; 78: 783-809.
2. Koutnikova H, Auwerx J,. Regulation of adipocyte differentiation. Ann Med 2001; 33: 556-561.
3. Xu H, Barnes GT, Yang Q, et al,. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003; 112: 1821-1830.
4. Weisberg SP, McCann D, Desai M, et al,. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112: 1796-1808.
5. Takeuchi O, Akira S,. Pattern recognition receptors and inflammation. Cell 2010; 140: 805-820.
6. Kawai T, Akira S,. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010; 11: 373-384.
7. Chen G, Shaw MH, Kim YG, Nuñez G,. NOD-like receptors: role in innate immunity and inflammatory disease. Annu Rev Pathol 2009; 4: 365-398.
8. Chamaillard M, Hashimoto M, Horie Y, et al,. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 2003; 4: 702-707.
9. Girardin SE, Boneca IG, Carneiro LA, et al,. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 2003; 300: 1584-1587.
10. Inohara N, Ogura Y, Fontalba A, et al,. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003; 278: 5509-5512.
11. Girardin SE, Boneca IG, Viala J, et al,. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 2003; 278: 8869-8872.
12. Park JH, Kim YG, McDonald C, et al,. RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J Immunol 2007; 178: 2380-2386.
13. Abbott DW, Wilkins A, Asara JM, Cantley LC,. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 2004; 14: 2217-2227.
14. Abbott DW, Yang Y, Hutti JE, et al,. Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains. Mol Cell Biol 2007; 27: 6012-6025.
15. Hasegawa M, Fujimoto Y, Lucas PC, et al,. A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J 2008; 27: 373-383.
16. Yang Y, Yin C, Pandey A, et al,. NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2. J Biol Chem 2007; 282: 36223-36229.
17. Girardin SE, Tournebize R, Mavris M, et al,. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep 2001; 2: 736-742.
18. Windheim M, Lang C, Peggie M, Plater LA, Cohen P,. Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. Biochem J 2007; 404: 179-190.
19. Kobayashi KS, Chamaillard M, Ogura Y, et al,. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005; 307: 731-734.
20. Magalhaes JG, Sorbara MT, Girardin SE, Philpott DJ,. What is new with Nods ? Curr Opin Immunol 2011; 23: 29-34.
21. Kopp A, Buechler C, Neumeier M, et al,. Innate immunity and adipocyte function: ligand-specific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes. Obesity (Silver Spring) 2009; 17: 648-656.
22. Kopp A, Buechler C, Bala M, et al,. Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3. Endocrinology 2010; 151: 1097-1108.
23. Zhao L, Hu P, Zhou Y, Purohit J, Hwang D,. NOD1 activation induces proinflammatory gene expression and insulin resistance in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab 2011; 301: E587-E598.
24. Song MJ, Kim KH, Yoon JM, Kim JB,. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 2006; 346: 739-745.
25. Poulain-Godefroy O, Froguel P,. Preadipocyte response and impairment of differentiation in an inflammatory environment. Biochem Biophys Res Commun 2007; 356: 662-667.
26. Poulain-Godefroy O, Le Bacquer O, Plancq P, et al,. Inflammatory role of Toll-like receptors in human and murine adipose tissue. Mediators Inflamm 2010; 2010: 823486.
27. Oort PJ, Warden CH, Baumann TK, Knotts TA, Adams SH,. Characterization of Tusc5, an adipocyte gene co-expressed in peripheral neurons. Mol Cell Endocrinol 2007; 276: 24-35.
28. Orlicky DJ, DeGregori J, Schaack J,. Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells. J Lipid Res 2001; 42: 910-915.
29. Ross SA, Song X, Burney MW, Kasai Y, Orlicky DJ,. Efficient adenovirus transduction of 3T3-L1 adipocytes stably expressing coxsackie-adenovirus receptor. Biochem Biophys Res Commun 2003; 302: 354-358.
30. Jobin C, Panja A, Hellerbrand C, et al,. Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells. J Immunol 1998; 160: 410-418.
31. Stofkova A,. Leptin and adiponectin: from energy and metabolic dysbalance to inflammation and autoimmunity. Endocr Regul 2009; 43: 157-168.
32. Fantuzzi G, Faggioni R,. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol 2000; 68: 437-446.
33. Whitehead JP, Richards AA, Hickman IJ, Macdonald GA, Prins JB,. Adiponectin-a key adipokine in the metabolic syndrome. Diabetes Obes Metab 2006; 8: 264-280.
34. Lin Y, Lee H, Berg AH, et al,. The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. J Biol Chem 2000; 275: 24255-24263.
35. Suzawa M, Takada I, Yanagisawa J, et al,. Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol 2003; 5: 224-230.
36. Kim HS, Shin TH, Yang SR, et al,. Implication of NOD1 and NOD2 for the differentiation of multipotent mesenchymal stem cells derived from human umbilical cord blood. PLoS ONE 2010; 5: e15369.
37. Ye J, Gimble JM,. Regulation of stem cell differentiation in adipose tissue by chronic inflammation. Clin Exp Pharmacol Physiol 2011; 38: 872-878.
38. Fantuzzi G,. Three questions about leptin and immunity. Brain Behav Immun 2009; 23: 405-410.
39. Travassos LH, Carneiro LA, Ramjeet M, et al,. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010; 11: 55-62.
40. Singh R, Xiang Y, Wang Y, et al,. Autophagy regulates adipose mass and differentiation in mice. J Clin Invest 2009; 119: 3329-3339.