Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2

Structure

Volumn 21, Issue 9, 2013, Pages 1571-1580

  Aglietti, Robin A ^a   Floor, Stephen N ^a   McClendon, Chris L ^a   Jacobson, Matthew P ^a   Gross, John D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID; BASE; ENZYME; ENZYME DCP2; MESSENGER RNA; METAL ION; NUDIX HYDROLASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMISTRY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME KINETICS; METAL BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; STIMULATION;

AMINO ACID SUBSTITUTION; BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENDORIBONUCLEASES; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84883488802     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2013.06.021     Document Type: Article

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