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Volumn 21, Issue 5, 2013, Pages 249-256

Endothelin in coronary artery disease and myocardial infarction

Author keywords

arrhythmia; atherosclerosis; endothelin; heart failure; myocardial infarction

Indexed keywords

ADRENALIN; ANGIOTENSIN II; BONE MORPHOGENETIC PROTEIN 9; BOSENTAN; BRADYKININ; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DARUSENTAN; ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENRASENTAN; G PROTEIN COUPLED RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; INSULIN; INTERLEUKIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NATRIURETIC FACTOR; NITRIC OXIDE; PHOSPHOLIPASE C; PLACEBO; PREPROENDOTHELIN 1; PROSTAGLANDIN; REACTIVE OXYGEN METABOLITE; TEZOSENTAN; THROMBIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84883463035     PISSN: 10615377     EISSN: 15384683     Source Type: Journal    
DOI: 10.1097/CRD.0b013e318283f65a     Document Type: Review
Times cited : (72)

References (105)
  • 1
    • 34447319923 scopus 로고    scopus 로고
    • Epidemiology of myocardial infarction
    • ix
    • Roger VL. Epidemiology of myocardial infarction. Med Clin North Am. 2007;91:537-552; ix.
    • (2007) Med Clin North Am , vol.91 , pp. 537-552
    • Roger, V.L.1
  • 2
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, S.3
  • 3
    • 0034619523 scopus 로고    scopus 로고
    • Endothelins and endothelin receptor antagonists: Therapeutic considerations for a novel class of cardiovascular drugs
    • Lüscher TF, Barton M. Endothelins and endothelin receptor antagonists: therapeutic considerations for a novel class of cardiovascular drugs. Circulation. 2000;102:2434-2440.
    • (2000) Circulation , vol.102 , pp. 2434-2440
    • Lüscher, T.F.1    Barton, M.2
  • 4
    • 48849094089 scopus 로고    scopus 로고
    • Endothelin: 20 years from discovery to therapy
    • Barton M, Yanagisawa M. Endothelin: 20 years from discovery to therapy. Can J Physiol Pharmacol. 2008;86:485-498.
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 485-498
    • Barton, M.1    Yanagisawa, M.2
  • 5
    • 0028358673 scopus 로고
    • Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch
    • Macarthur H, Warner TD, Wood EG, et al. Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch. Biochem Biophys Res Commun. 1994;200:395-400.
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 395-400
    • Macarthur, H.1    Warner, T.D.2    Wood, E.G.3
  • 6
  • 7
    • 0027235561 scopus 로고
    • Endothelins: Circulating plasma levels and presence in other biologic fluids
    • Battistini B, D'Orléans-Juste P, Sirois P. Endothelins: circulating plasma levels and presence in other biologic fluids. Lab Invest. 1993;68:600-628.
    • (1993) Lab Invest , vol.68 , pp. 600-628
    • Battistini, B.1    D'orléans-Juste, P.2    Sirois, P.3
  • 8
    • 0027538163 scopus 로고
    • Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium
    • Molenaar P, O'Reilly G, Sharkey A, et al. Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium. Circ Res. 1993;72:526-538.
    • (1993) Circ Res , vol.72 , pp. 526-538
    • Molenaar, P.1    O'reilly, G.2    Sharkey, A.3
  • 9
    • 79952278486 scopus 로고    scopus 로고
    • Endothelial cell-specific ETB receptor knockout: Autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1
    • Kelland NF, Kuc RE, McLean DL, et al. Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1. Can J Physiol Pharmacol. 2010;88:644-651.
    • (2010) Can J Physiol Pharmacol , vol.88 , pp. 644-651
    • Kelland, N.F.1    Kuc, R.E.2    McLean, D.L.3
  • 10
    • 0030068247 scopus 로고    scopus 로고
    • Influence of endothelin 1 on human atrial myocardium-myocardial function and subcellular pathways
    • Meyer M, Lehnart S, Pieske B, et al. Influence of endothelin 1 on human atrial myocardium-myocardial function and subcellular pathways. Basic Res Cardiol. 1996;91:86-93.
    • (1996) Basic Res Cardiol , vol.91 , pp. 86-93
    • Meyer, M.1    Lehnart, S.2    Pieske, B.3
  • 12
    • 0026230197 scopus 로고
    • Characterization of positive inotropic effect of endothelin on mammalian ventricular myocardium
    • Takanashi M, Endoh M. Characterization of positive inotropic effect of endothelin on mammalian ventricular myocardium. Am J Physiol. 1991;261(3 Pt 2):H611-H619.
    • (1991) Am J Physiol , vol.261 , Issue.3 PART 2
    • Takanashi, M.1    Endoh, M.2
  • 13
    • 79953025603 scopus 로고    scopus 로고
    • Further evidence for a role of endothelin-1 (ET-1) in critical limb ischaemia
    • Dashwood MR, Tsui JC. Further evidence for a role of endothelin-1 (ET-1) in critical limb ischaemia. J Cell Commun Signal. 2011;5:45-49.
    • (2011) J Cell Commun Signal , vol.5 , pp. 45-49
    • Dashwood, M.R.1    Tsui, J.C.2
  • 14
    • 77952891842 scopus 로고    scopus 로고
    • Endothelium-derived endothelin-1
    • Thorin E, Webb DJ. Endothelium-derived endothelin-1. Pflugers Arch. 2010;459:951-958.
    • (2010) Pflugers Arch , vol.459 , pp. 951-958
    • Thorin, E.1    Webb, D.J.2
  • 15
    • 64949124561 scopus 로고    scopus 로고
    • Vascular control in humans: Focus on the coronary microcirculation
    • Liu Y, Gutterman DD. Vascular control in humans: focus on the coronary microcirculation. Basic Res Cardiol. 2009;104:211-227.
    • (2009) Basic Res Cardiol , vol.104 , pp. 211-227
    • Liu, Y.1    Gutterman, D.D.2
  • 16
    • 34247093323 scopus 로고    scopus 로고
    • Coronary endothelium expresses a pathologic gene pattern compared to aortic endothelium: Correlation of asynchronous hemodynamics and pathology in vivo
    • Dancu MB, Tarbell JM. Coronary endothelium expresses a pathologic gene pattern compared to aortic endothelium: correlation of asynchronous hemodynamics and pathology in vivo. Atherosclerosis. 2007;192:9-14.
    • (2007) Atherosclerosis , vol.192 , pp. 9-14
    • Dancu, M.B.1    Tarbell, J.M.2
  • 17
    • 0033867351 scopus 로고    scopus 로고
    • Endogenous endothelin maintains coronary artery tone by endothelin type A receptor stimulation in patients undergoing coronary arteriography
    • Kyriakides ZS, Kremastinos DT, Bofilis E, et al. Endogenous endothelin maintains coronary artery tone by endothelin type A receptor stimulation in patients undergoing coronary arteriography. Heart. 2000;84:176-182.
    • (2000) Heart , vol.84 , pp. 176-182
    • Kyriakides, Z.S.1    Kremastinos, D.T.2    Bofilis, E.3
  • 18
    • 0035806922 scopus 로고    scopus 로고
    • Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries
    • Kinlay S, Behrendt D, Wainstein M, et al. Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries. Circulation. 2001;104:1114-1118.
    • (2001) Circulation , vol.104 , pp. 1114-1118
    • Kinlay, S.1    Behrendt, D.2    Wainstein, M.3
  • 19
    • 0028829513 scopus 로고
    • Endothelin in coronary endothelial dysfunction and early atherosclerosis in humans
    • Lerman A, Holmes DR Jr, Bell MR, et al. Endothelin in coronary endothelial dysfunction and early atherosclerosis in humans. Circulation. 1995;92:2426-2431.
    • (1995) Circulation , vol.92 , pp. 2426-2431
    • Lerman, A.1    Holmes Jr., D.R.2    Bell, M.R.3
  • 20
    • 37349109693 scopus 로고    scopus 로고
    • Mechanisms of ET-1-induced endothelial dysfunction
    • Iglarz M, Clozel M. Mechanisms of ET-1-induced endothelial dysfunction. J Cardiovasc Pharmacol. 2007;50:621-628.
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 621-628
    • Iglarz, M.1    Clozel, M.2
  • 21
    • 79959690273 scopus 로고    scopus 로고
    • Endothelium-derived vasoactive agents, AT1 receptors and inflammation
    • MacKenzie A. Endothelium-derived vasoactive agents, AT1 receptors and inflammation. Pharmacol Ther. 2011;131:187-203.
    • (2011) Pharmacol Ther , vol.131 , pp. 187-203
    • Mackenzie, A.1
  • 22
    • 0034943021 scopus 로고    scopus 로고
    • Oxidative stress increases endothelin-1 synthesis in human coronary artery smooth muscle cells
    • Kähler J, Ewert A, Weckmüller J, et al. Oxidative stress increases endothelin-1 synthesis in human coronary artery smooth muscle cells. J Cardiovasc Pharmacol. 2001;38:49-57.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 49-57
    • Kähler, J.1    Ewert, A.2    Weckmüller, J.3
  • 23
    • 77950845380 scopus 로고    scopus 로고
    • Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress
    • Piechota A, Polanczyk A, Goraca A. Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress. Pharmacol Rep. 2010;62:28-34.
    • (2010) Pharmacol Rep , vol.62 , pp. 28-34
    • Piechota, A.1    Polanczyk, A.2    Goraca, A.3
  • 24
    • 21244456905 scopus 로고    scopus 로고
    • Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: Role of ETB receptor, NADPH oxidase and caveolin-1
    • Dong F, Zhang X, Wold LE, et al. Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1. Br J Pharmacol. 2005;145:323-333.
    • (2005) Br J Pharmacol , vol.145 , pp. 323-333
    • Dong, F.1    Zhang, X.2    Wold, L.E.3
  • 25
    • 0033537665 scopus 로고    scopus 로고
    • Endothelin-1 and its mRNA in the wall layers of human arteries ex vivo
    • Rossi GP, Colonna S, Pavan E, et al. Endothelin-1 and its mRNA in the wall layers of human arteries ex vivo. Circulation. 1999;99:1147-1155.
    • (1999) Circulation , vol.99 , pp. 1147-1155
    • Rossi, G.P.1    Colonna, S.2    Pavan, E.3
  • 26
    • 79951914544 scopus 로고    scopus 로고
    • Vascular gene expression in mice overexpressing human endothelin-1 targeted to the endothelium
    • Simeone SM, Li MW, Paradis P, et al. Vascular gene expression in mice overexpressing human endothelin-1 targeted to the endothelium. Physiol Genomics. 2011;43:148-160.
    • (2011) Physiol Genomics , vol.43 , pp. 148-160
    • Simeone, S.M.1    Li, M.W.2    Paradis, P.3
  • 27
    • 0032564279 scopus 로고    scopus 로고
    • Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice
    • Barton M, Haudenschild CC, d'Uscio LV, et al. Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A. 1998;95:14367-14372.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14367-14372
    • Barton, M.1    Haudenschild, C.C.2    D'uscio, L.V.3
  • 28
    • 0036255170 scopus 로고    scopus 로고
    • Effects of chronic administration of the novel endothelin antagonist J-104132 on endothelial dysfunction in streptozotocin-induced diabetic rat
    • Kanie N, Kamata K. Effects of chronic administration of the novel endothelin antagonist J-104132 on endothelial dysfunction in streptozotocin-induced diabetic rat. Br J Pharmacol. 2002;135:1935-1942.
    • (2002) Br J Pharmacol , vol.135 , pp. 1935-1942
    • Kanie, N.1    Kamata, K.2
  • 29
    • 0033528717 scopus 로고    scopus 로고
    • Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia
    • Best PJ, McKenna CJ, Hasdai D, et al. Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia. Circulation. 1999;99:1747-1752.
    • (1999) Circulation , vol.99 , pp. 1747-1752
    • Best, P.J.1    McKenna, C.J.2    Hasdai, D.3
  • 30
    • 52049097771 scopus 로고    scopus 로고
    • Efficacy and safety of atrasentan in patients with cardiovascular risk and early atherosclerosis
    • Raichlin E, Prasad A, Mathew V, et al. Efficacy and safety of atrasentan in patients with cardiovascular risk and early atherosclerosis. Hypertension. 2008;52:522-528.
    • (2008) Hypertension , vol.52 , pp. 522-528
    • Raichlin, E.1    Prasad, A.2    Mathew, V.3
  • 31
    • 77957289366 scopus 로고    scopus 로고
    • Long-term administration of endothelin receptor antagonist improves coronary endothelial function in patients with early atherosclerosis
    • Reriani M, Raichlin E, Prasad A, et al. Long-term administration of endothelin receptor antagonist improves coronary endothelial function in patients with early atherosclerosis. Circulation. 2010;122:958-966.
    • (2010) Circulation , vol.122 , pp. 958-966
    • Reriani, M.1    Raichlin, E.2    Prasad, A.3
  • 32
    • 79751535376 scopus 로고    scopus 로고
    • Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation
    • Kleinbongard P, B̈se D, Baars T, et al. Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation. Circ Res. 2011;108:344-352.
    • (2011) Circ Res , vol.108 , pp. 344-352
    • Kleinbongard, P.1    B̈se, D.2    Baars, T.3
  • 34
    • 0025811543 scopus 로고
    • Plasma endothelin levels during myocardial ischemia and reperfusion
    • Tsuji S, Sawamura A, Watanabe H, et al. Plasma endothelin levels during myocardial ischemia and reperfusion. Life Sci. 1991;48:1745-1749.
    • (1991) Life Sci , vol.48 , pp. 1745-1749
    • Tsuji, S.1    Sawamura, A.2    Watanabe, H.3
  • 35
    • 0025356453 scopus 로고
    • Endothelin in myocardial infarction
    • Watanabe T, Suzuki N, Shimamoto N, et al. Endothelin in myocardial infarction. Nature. 1990;344:114.
    • (1990) Nature , vol.344 , pp. 114
    • Watanabe, T.1    Suzuki, N.2    Shimamoto, N.3
  • 36
    • 0025737363 scopus 로고
    • Contribution of endogenous endothelin to the extension of myocardial infarct size in rats
    • Watanabe T, Suzuki N, Shimamoto N, et al. Contribution of endogenous endothelin to the extension of myocardial infarct size in rats. Circ Res. 1991;69:370-377.
    • (1991) Circ Res , vol.69 , pp. 370-377
    • Watanabe, T.1    Suzuki, N.2    Shimamoto, N.3
  • 37
    • 0034991506 scopus 로고    scopus 로고
    • Regional expression of endothelin- 1, ANP, IGF-1, and LV wall stress in the infarcted rat heart
    • Loennechen JP, Støylen A, Beisvag V, et al. Regional expression of endothelin- 1, ANP, IGF-1, and LV wall stress in the infarcted rat heart. Am J Physiol Heart Circ Physiol. 2001;280:H2902-H2910.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Loennechen, J.P.1    Støylen, A.2    Beisvag, V.3
  • 38
    • 0024383528 scopus 로고
    • Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction
    • Miyauchi T, Yanagisawa M, Tomizawa T, et al. Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet. 1989;2:53-54.
    • (1989) Lancet , vol.2 , pp. 53-54
    • Miyauchi, T.1    Yanagisawa, M.2    Tomizawa, T.3
  • 39
    • 0025892889 scopus 로고
    • Increased plasma endothelin- 1 in the early hours of acute myocardial infarction
    • Stewart DJ, Kubac G, Costello KB, et al. Increased plasma endothelin- 1 in the early hours of acute myocardial infarction. J Am Coll Cardiol. 1991;18:38-43.
    • (1991) J Am Coll Cardiol , vol.18 , pp. 38-43
    • Stewart, D.J.1    Kubac, G.2    Costello, K.B.3
  • 40
    • 0025276505 scopus 로고
    • Circulating immunoreactive endothelin in ischemic heart disease
    • Yasuda M, Kohno M, Tahara A, et al. Circulating immunoreactive endothelin in ischemic heart disease. Am Heart J. 1990;119:801-806.
    • (1990) Am Heart J , vol.119 , pp. 801-806
    • Yasuda, M.1    Kohno, M.2    Tahara, A.3
  • 41
    • 85047676588 scopus 로고
    • Release of endothelin from the porcine heart after short term coronary artery occlusion
    • Tønnessen T, Naess PA, Kirkebøen KA, et al. Release of endothelin from the porcine heart after short term coronary artery occlusion. Cardiovasc Res. 1993;27:1482-1485.
    • (1993) Cardiovasc Res , vol.27 , pp. 1482-1485
    • Tønnessen, T.1    Naess, P.A.2    Kirkebøen, K.A.3
  • 42
    • 0028850848 scopus 로고
    • Local overflow and enhanced tissue content of endothelin following myocardial ischaemia and reperfusion in the pig: Modulation by L-arginine
    • Wang QD, Hemsén A, Li XS, et al. Local overflow and enhanced tissue content of endothelin following myocardial ischaemia and reperfusion in the pig: modulation by L-arginine. Cardiovasc Res. 1995;29:44-49.
    • (1995) Cardiovasc Res , vol.29 , pp. 44-49
    • Wang, Q.D.1    Hemsén, A.2    Li, X.S.3
  • 43
    • 0028901625 scopus 로고
    • Increased in vivo expression and production of endothelin-1 by porcine cardiomyocytes subjected to ischemia
    • Tønnessen T, Giaid A, Saleh D, et al. Increased in vivo expression and production of endothelin-1 by porcine cardiomyocytes subjected to ischemia. Circ Res. 1995;76:767-772.
    • (1995) Circ Res , vol.76 , pp. 767-772
    • Tønnessen, T.1    Giaid, A.2    Saleh, D.3
  • 44
    • 19844364299 scopus 로고    scopus 로고
    • Prognostic value of circulating levels of endothelin-1 in patients after acute myocardial infarction undergoing primary coronary angioplasty
    • Yip HK, Wu CJ, Chang HW, et al. Prognostic value of circulating levels of endothelin-1 in patients after acute myocardial infarction undergoing primary coronary angioplasty. Chest. 2005;127:1491-1497.
    • (2005) Chest , vol.127 , pp. 1491-1497
    • Yip, H.K.1    Wu, C.J.2    Chang, H.W.3
  • 45
    • 0028204079 scopus 로고
    • Plasma endothelin determination as a prognostic indicator of 1-year mortality after acute myocardial infarction
    • Omland T, Lie RT, Aakvaag A, et al. Plasma endothelin determination as a prognostic indicator of 1-year mortality after acute myocardial infarction. Circulation. 1994;89:1573-1579.
    • (1994) Circulation , vol.89 , pp. 1573-1579
    • Omland, T.1    Lie, R.T.2    Aakvaag, A.3
  • 46
    • 22744435615 scopus 로고    scopus 로고
    • Endothelin receptor - A blockade decreases ventricular arrhythmias after myocardial infarction in rats
    • Baltogiannis GG, Tsalikakis DG, Mitsi AC, et al. Endothelin receptor-a blockade decreases ventricular arrhythmias after myocardial infarction in rats. Cardiovasc Res. 2005;67:647-654.
    • (2005) Cardiovasc Res , vol.67 , pp. 647-654
    • Baltogiannis, G.G.1    Tsalikakis, D.G.2    Mitsi, A.C.3
  • 47
    • 0037005775 scopus 로고    scopus 로고
    • Short-term endothelin receptor blockade with tezosentan has both immediate and long-term beneficial effects in rats with myocardial infarction
    • Clozel M, Qiu C, Qiu CS, et al. Short-term endothelin receptor blockade with tezosentan has both immediate and long-term beneficial effects in rats with myocardial infarction. J Am Coll Cardiol. 2002;39:142-147.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 142-147
    • Clozel, M.1    Qiu, C.2    Qiu, C.S.3
  • 48
    • 37649022744 scopus 로고    scopus 로고
    • Effects of dual endothelin receptor blockade on sympathetic activation and arrhythmogenesis during acute myocardial infarction in rats
    • Kolettis TM, Baltogiannis GG, Tsalikakis DG, et al. Effects of dual endothelin receptor blockade on sympathetic activation and arrhythmogenesis during acute myocardial infarction in rats. Eur J Pharmacol. 2008;580:241-249.
    • (2008) Eur J Pharmacol , vol.580 , pp. 241-249
    • Kolettis, T.M.1    Baltogiannis, G.G.2    Tsalikakis, D.G.3
  • 49
    • 0032169202 scopus 로고    scopus 로고
    • The endothelin A receptor antagonist LU 135252 protects the myocardium from neutrophil injury during ischaemia/ reperfusion
    • Gonon AT, Wang QD, Pernow J. The endothelin A receptor antagonist LU 135252 protects the myocardium from neutrophil injury during ischaemia/ reperfusion. Cardiovasc Res. 1998;39:674-682.
    • (1998) Cardiovasc Res , vol.39 , pp. 674-682
    • Gonon, A.T.1    Wang, Q.D.2    Pernow, J.3
  • 50
    • 0027279308 scopus 로고
    • Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart
    • López Farré A, Riesco A, Espinosa G, et al. Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart. Circulation. 1993;88:1166-1171.
    • (1993) Circulation , vol.88 , pp. 1166-1171
    • López Farré, A.1    Riesco, A.2    Espinosa, G.3
  • 51
    • 31044447786 scopus 로고    scopus 로고
    • Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury
    • Ozdemir R, Parlakpinar H, Polat A, et al. Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury. Toxicology. 2006;219:142-149.
    • (2006) Toxicology , vol.219 , pp. 142-149
    • Ozdemir, R.1    Parlakpinar, H.2    Polat, A.3
  • 52
    • 78049287600 scopus 로고    scopus 로고
    • Endothelin receptor antagonist BQ-123 ameliorates myocardial ischemic-reperfusion injury in rats: A hemodynamic, biochemical, histopathological and electron microscopic evidence
    • Goyal SN, Bharti S, Arora S, et al. Endothelin receptor antagonist BQ-123 ameliorates myocardial ischemic-reperfusion injury in rats: a hemodynamic, biochemical, histopathological and electron microscopic evidence. Biomed Pharmacother. 2010;64:639-646.
    • (2010) Biomed Pharmacother , vol.64 , pp. 639-646
    • Goyal, S.N.1    Bharti, S.2    Arora, S.3
  • 53
    • 33646750164 scopus 로고    scopus 로고
    • Cardioprotective effects of bosentan, a mixed endothelin type A and B receptor antagonist, during myocardial ischaemia and reperfusion in rats
    • Singh AD, Amit S, Kumar OS, et al. Cardioprotective effects of bosentan, a mixed endothelin type A and B receptor antagonist, during myocardial ischaemia and reperfusion in rats. Basic Clin Pharmacol Toxicol. 2006;98:604-610.
    • (2006) Basic Clin Pharmacol Toxicol , vol.98 , pp. 604-610
    • Singh, A.D.1    Amit, S.2    Kumar, O.S.3
  • 54
    • 80555146633 scopus 로고    scopus 로고
    • CPU0213, a novel endothelin type A and type B receptor antagonist, protects against myocardial ischemia/reperfusion injury in rats
    • Wang ZY, Zhang W, Li XZ, et al. CPU0213, a novel endothelin type A and type B receptor antagonist, protects against myocardial ischemia/reperfusion injury in rats. Braz J Med Biol Res. 2011;44:1148-1155.
    • (2011) Braz J Med Biol Res , vol.44 , pp. 1148-1155
    • Wang, Z.Y.1    Zhang, W.2    Li, X.Z.3
  • 55
    • 84860774964 scopus 로고    scopus 로고
    • Systemic endothelin receptor blockade in ST-segment elevation acute coronary syndrome protects the microvasculature: A randomised pilot study
    • Adlbrecht C, Andreas M, Redwan B, et al. Systemic endothelin receptor blockade in ST-segment elevation acute coronary syndrome protects the microvasculature: a randomised pilot study. EuroIntervention. 2012;7:1386-1395.
    • (2012) EuroIntervention , vol.7 , pp. 1386-1395
    • Adlbrecht, C.1    Andreas, M.2    Redwan, B.3
  • 56
    • 0034613208 scopus 로고    scopus 로고
    • Role of endogenous endothelins in catecholamine secretion in the rat adrenal gland
    • Nagayama T, Kuwakubo F, Matsumoto T, et al. Role of endogenous endothelins in catecholamine secretion in the rat adrenal gland. Eur J Pharmacol. 2000;406:69-74.
    • (2000) Eur J Pharmacol , vol.406 , pp. 69-74
    • Nagayama, T.1    Kuwakubo, F.2    Matsumoto, T.3
  • 57
    • 33846655795 scopus 로고    scopus 로고
    • Endothelin receptors, localized in sympathetic nerve terminals of the heart, modulate norepinephrine release and reperfusion arrhythmias
    • Isaka M, Kudo A, Imamura M, et al. Endothelin receptors, localized in sympathetic nerve terminals of the heart, modulate norepinephrine release and reperfusion arrhythmias. Basic Res Cardiol. 2007;102:154-162.
    • (2007) Basic Res Cardiol , vol.102 , pp. 154-162
    • Isaka, M.1    Kudo, A.2    Imamura, M.3
  • 58
    • 12844261619 scopus 로고    scopus 로고
    • Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts
    • Yamamoto S, Matsumoto N, Kanazawa M, et al. Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts. Circulation. 2005;111:302-309.
    • (2005) Circulation , vol.111 , pp. 302-309
    • Yamamoto, S.1    Matsumoto, N.2    Kanazawa, M.3
  • 59
    • 84864929771 scopus 로고    scopus 로고
    • Endothelin-B receptors and left ventricular dysfunction after regional versus global ischaemia-reperfusion in rat hearts
    • Bibli SI, Toli EV, Vilaeti AD, et al. Endothelin-B receptors and left ventricular dysfunction after regional versus global ischaemia-reperfusion in rat hearts. Cardiol Res Pract. 2012;2012:986813.
    • (2012) Cardiol Res Pract , vol.2012 , pp. 986813
    • Bibli, S.I.1    Toli, E.V.2    Vilaeti, A.D.3
  • 60
    • 77950360102 scopus 로고    scopus 로고
    • Endothelin-B receptors and ventricular arrhythmogenesis in the rat model of acute myocardial infarction
    • Oikonomidis DL, Tsalikakis DG, Baltogiannis GG, et al. Endothelin-B receptors and ventricular arrhythmogenesis in the rat model of acute myocardial infarction. Basic Res Cardiol. 2010;105:235-245.
    • (2010) Basic Res Cardiol , vol.105 , pp. 235-245
    • Oikonomidis, D.L.1    Tsalikakis, D.G.2    Baltogiannis, G.G.3
  • 61
    • 33748787687 scopus 로고    scopus 로고
    • Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes
    • Proven A, Roderick HL, Conway SJ, et al. Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes. J Cell Sci. 2006;119(Pt 16):3363-3375.
    • (2006) J Cell Sci , vol.119 , Issue.PART 16 , pp. 3363-3375
    • Proven, A.1    Roderick, H.L.2    Conway, S.J.3
  • 62
    • 0000942146 scopus 로고    scopus 로고
    • Mechanism of endothelin-induced malignant ventricular arrhythmias in dogs
    • Merkely B, Gellér L, Tóth M, et al. Mechanism of endothelin-induced malignant ventricular arrhythmias in dogs. J Cardiovasc Pharmacol. 1998;31(suppl 1):S437-S439.
    • (1998) J Cardiovasc Pharmacol , vol.31 , Issue.SUPPL. 1
    • Merkely, B.1    Gellér, L.2    Tóth, M.3
  • 63
    • 0030798910 scopus 로고    scopus 로고
    • Endothelin-1 inhibits the slow component of cardiac delayed rectifier K+ currents via a pertussis toxin-sensitive mechanism
    • Washizuka T, Horie M, Watanuki M, et al. Endothelin-1 inhibits the slow component of cardiac delayed rectifier K+ currents via a pertussis toxin-sensitive mechanism. Circ Res. 1997;81:211-218.
    • (1997) Circ Res , vol.81 , pp. 211-218
    • Washizuka, T.1    Horie, M.2    Watanuki, M.3
  • 64
    • 0035253797 scopus 로고    scopus 로고
    • Endothelin and cardiac arrhythmias: Do endothelin antagonists have a therapeutic potential as antiarrhythmic drugs?
    • Duru F, Barton M, Lüscher TF, et al. Endothelin and cardiac arrhythmias: do endothelin antagonists have a therapeutic potential as antiarrhythmic drugs? Cardiovasc Res. 2001;49:272-280.
    • (2001) Cardiovasc Res , vol.49 , pp. 272-280
    • Duru, F.1    Barton, M.2    Lüscher, T.F.3
  • 65
    • 78049434109 scopus 로고    scopus 로고
    • Do endothelin receptor antagonists have an antiarrhythmic potential during acute myocardial infarction? Evidence from experimental studies
    • Oikonomidis DL, Baltogiannis GG, Kolettis TM. Do endothelin receptor antagonists have an antiarrhythmic potential during acute myocardial infarction? Evidence from experimental studies. J Interv Card Electrophysiol. 2010;28:157-165.
    • (2010) J Interv Card Electrophysiol , vol.28 , pp. 157-165
    • Oikonomidis, D.L.1    Baltogiannis, G.G.2    Kolettis, T.M.3
  • 66
    • 0032127010 scopus 로고    scopus 로고
    • Effects of reperfusion on arrhythmias and death after coronary artery occlusion in the rat: Increased electrical stability independent of myocardial salvage
    • Opitz CF, Finn PV, Pfeffer MA, et al. Effects of reperfusion on arrhythmias and death after coronary artery occlusion in the rat: increased electrical stability independent of myocardial salvage. J Am Coll Cardiol. 1998;32:261-267.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 261-267
    • Opitz, C.F.1    Finn, P.V.2    Pfeffer, M.A.3
  • 67
    • 0032168356 scopus 로고    scopus 로고
    • Endothelin and ischaemic arrhythmiasantiarrhythmic or arrhythmogenic?
    • Sharif I, Kane KA, Wainwright CL. Endothelin and ischaemic arrhythmiasantiarrhythmic or arrhythmogenic? Cardiovasc Res. 1998;39:625-632.
    • (1998) Cardiovasc Res , vol.39 , pp. 625-632
    • Sharif, I.1    Kane, K.A.2    Wainwright, C.L.3
  • 68
    • 0030296495 scopus 로고    scopus 로고
    • Endothelin-1 can reduce infarct size through protein kinase C and KATP channels in the isolated rat heart
    • Bugge E, Ytrehus K. Endothelin-1 can reduce infarct size through protein kinase C and KATP channels in the isolated rat heart. Cardiovasc Res. 1996;32:920-929.
    • (1996) Cardiovasc Res , vol.32 , pp. 920-929
    • Bugge, E.1    Ytrehus, K.2
  • 69
    • 0029987782 scopus 로고    scopus 로고
    • Pretreatment with endothelin-1 mimics ischemic preconditioning against infarction in isolated rabbit heart
    • Wang P, Gallagher KP, Downey JM, et al. Pretreatment with endothelin-1 mimics ischemic preconditioning against infarction in isolated rabbit heart. J Mol Cell Cardiol. 1996;28:579-588.
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 579-588
    • Wang, P.1    Gallagher, K.P.2    Downey, J.M.3
  • 70
    • 14644412903 scopus 로고    scopus 로고
    • Endothelin-1 exerts a preconditioning- like cardioprotective effect against ischaemia/reperfusion injury via the ET(A) receptor and the mitochondrial K(ATP) channel in the rat in vivo
    • Gourine AV, Molosh AI, Poputnikov D, et al. Endothelin-1 exerts a preconditioning- like cardioprotective effect against ischaemia/reperfusion injury via the ET(A) receptor and the mitochondrial K(ATP) channel in the rat in vivo. Br J Pharmacol. 2005;144:331-337.
    • (2005) Br J Pharmacol , vol.144 , pp. 331-337
    • Gourine, A.V.1    Molosh, A.I.2    Poputnikov, D.3
  • 71
    • 79751501231 scopus 로고    scopus 로고
    • Effects of exogenous big endothelin- 1 on postischemic cardiac dysfunction and norepinephrine overflow in rat hearts
    • Tawa M, Fukumoto T, Ohkita M, et al. Effects of exogenous big endothelin- 1 on postischemic cardiac dysfunction and norepinephrine overflow in rat hearts. Hypertens Res. 2011;34:218-224.
    • (2011) Hypertens Res , vol.34 , pp. 218-224
    • Tawa, M.1    Fukumoto, T.2    Ohkita, M.3
  • 72
    • 79957714531 scopus 로고    scopus 로고
    • Contribution of nitric oxide in big endothelin-1-induced cardioprotective effects on ischemia/reperfusion injury in rat hearts
    • Tawa M, Fukumoto T, Ohkita M, et al. Contribution of nitric oxide in big endothelin-1-induced cardioprotective effects on ischemia/reperfusion injury in rat hearts. J Cardiovasc Pharmacol. 2011;57:575-578.
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 575-578
    • Tawa, M.1    Fukumoto, T.2    Ohkita, M.3
  • 73
    • 79751517236 scopus 로고    scopus 로고
    • Endothelin-1 during myocardial ischaemia: A double-edged sword?
    • Kolettis TM. Endothelin-1 during myocardial ischaemia: a double-edged sword? Hypertens Res. 2011;34:170-172.
    • (2011) Hypertens Res , vol.34 , pp. 170-172
    • Kolettis, T.M.1
  • 74
    • 34248645443 scopus 로고    scopus 로고
    • Management of acute decompensated heart failure
    • Dec GW. Management of acute decompensated heart failure. Curr Probl Cardiol. 2007;32:321-366.
    • (2007) Curr Probl Cardiol , vol.32 , pp. 321-366
    • Dec, G.W.1
  • 75
    • 0034895218 scopus 로고    scopus 로고
    • The dual endothelin receptor antagonist tezosentan acutely improves hemodynamic parameters in patients with advanced heart failure
    • Schalcher C, Cotter G, Reisin L, et al. The dual endothelin receptor antagonist tezosentan acutely improves hemodynamic parameters in patients with advanced heart failure. Am Heart J. 2001;142:340-349.
    • (2001) Am Heart J , vol.142 , pp. 340-349
    • Schalcher, C.1    Cotter, G.2    Reisin, L.3
  • 76
    • 0038414660 scopus 로고    scopus 로고
    • Randomized Intravenous TeZosentan Study-4 Investigators. Tezosentan in patients with acute heart failure and acute coronary syndromes: Results of the Randomized Intravenous TeZosentan Study (RITZ-4)
    • O'Connor CM, Gattis WA, Adams KF Jr, et al.; Randomized Intravenous TeZosentan Study-4 Investigators. Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4). J Am Coll Cardiol. 2003;41:1452-1457.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1452-1457
    • O'connor, C.M.1    Gattis, W.A.2    Adams Jr., K.F.3
  • 77
    • 35848944656 scopus 로고    scopus 로고
    • VERITAS Investigators. Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: The VERITAS randomized controlled trials
    • McMurray JJ, Teerlink JR, Cotter G, et al.; VERITAS Investigators. Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials. JAMA. 2007;298:2009-2019.
    • (2007) JAMA , vol.298 , pp. 2009-2019
    • McMurray, J.J.1    Teerlink, J.R.2    Cotter, G.3
  • 79
    • 15244363201 scopus 로고    scopus 로고
    • Chemokines in the ischemic myocardium: From inflammation to fibrosis
    • Frangogiannis NG. Chemokines in the ischemic myocardium: from inflammation to fibrosis. Inflamm Res. 2004;53:585-595.
    • (2004) Inflamm Res , vol.53 , pp. 585-595
    • Frangogiannis, N.G.1
  • 80
    • 0034074371 scopus 로고    scopus 로고
    • Infarct scar: A dynamic tissue
    • Sun Y, Weber KT. Infarct scar: a dynamic tissue. Cardiovasc Res. 2000;46: 250-256.
    • (2000) Cardiovasc Res , vol.46 , pp. 250-256
    • Sun, Y.1    Weber, K.T.2
  • 81
    • 85047675578 scopus 로고
    • Endothelin receptors in cultured adult rat cardiac fibroblasts
    • Katwa LC, Guarda E, Weber KT. Endothelin receptors in cultured adult rat cardiac fibroblasts. Cardiovasc Res. 1993;27:2125-2129.
    • (1993) Cardiovasc Res , vol.27 , pp. 2125-2129
    • Katwa, L.C.1    Guarda, E.2    Weber, K.T.3
  • 82
    • 85047679521 scopus 로고
    • Effects of endothelins on collagen turnover in cardiac fibroblasts
    • Guarda E, Katwa LC, Myers PR, et al. Effects of endothelins on collagen turnover in cardiac fibroblasts. Cardiovasc Res. 1993;27:2130-2134.
    • (1993) Cardiovasc Res , vol.27 , pp. 2130-2134
    • Guarda, E.1    Katwa, L.C.2    Myers, P.R.3
  • 83
    • 0034747794 scopus 로고    scopus 로고
    • Regulation of endothelin-1 synthesis in human pulmonary arterial smooth muscle cells. Effects of transforming growth factor-beta and hypoxia
    • Markewitz BA, Farrukh IS, Chen Y, et al. Regulation of endothelin-1 synthesis in human pulmonary arterial smooth muscle cells. Effects of transforming growth factor-beta and hypoxia. Cardiovasc Res. 2001;49:200-206.
    • (2001) Cardiovasc Res , vol.49 , pp. 200-206
    • Markewitz, B.A.1    Farrukh, I.S.2    Chen, Y.3
  • 84
    • 77958504428 scopus 로고    scopus 로고
    • Endothelin-1 stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by endothelin receptor transactivation of the transforming growth factor-[beta] type i receptor
    • Little PJ, Burch ML, Getachew R, et al. Endothelin-1 stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by endothelin receptor transactivation of the transforming growth factor-[beta] type I receptor. J Cardiovasc Pharmacol. 2010;56:360-368.
    • (2010) J Cardiovasc Pharmacol , vol.56 , pp. 360-368
    • Little, P.J.1    Burch, M.L.2    Getachew, R.3
  • 85
    • 22744459775 scopus 로고    scopus 로고
    • Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells
    • Rodriguez-Vita J, Ruiz-Ortega M, Rupérez M, et al. Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells. Circ Res. 2005;97:125-134.
    • (2005) Circ Res , vol.97 , pp. 125-134
    • Rodriguez-Vita, J.1    Ruiz-Ortega, M.2    Rupérez, M.3
  • 86
    • 0030691955 scopus 로고    scopus 로고
    • Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: Possible involvement of myocardial endothelin system in ventricular remodeling
    • Fraccarollo D, Hu K, Galuppo P, et al. Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: possible involvement of myocardial endothelin system in ventricular remodeling. Circulation. 1997;96:3963-3973.
    • (1997) Circulation , vol.96 , pp. 3963-3973
    • Fraccarollo, D.1    Hu, K.2    Galuppo, P.3
  • 87
    • 0035940394 scopus 로고    scopus 로고
    • Long-term effects of nonselective endothelin A and B receptor antagonism in postinfarction rat: Importance of timing
    • Nguyen QT, Cernacek P, Sirois MG, et al. Long-term effects of nonselective endothelin A and B receptor antagonism in postinfarction rat: importance of timing. Circulation. 2001;104:2075-2081.
    • (2001) Circulation , vol.104 , pp. 2075-2081
    • Nguyen, Q.T.1    Cernacek, P.2    Sirois, M.G.3
  • 88
    • 0036272196 scopus 로고    scopus 로고
    • Collagen accumulation after myocardial infarction: Effects of ETA receptor blockade and implications for early remodeling
    • Fraccarollo D, Galuppo P, Bauersachs J, et al. Collagen accumulation after myocardial infarction: effects of ETA receptor blockade and implications for early remodeling. Cardiovasc Res. 2002;54:559-567.
    • (2002) Cardiovasc Res , vol.54 , pp. 559-567
    • Fraccarollo, D.1    Galuppo, P.2    Bauersachs, J.3
  • 89
    • 0031657424 scopus 로고    scopus 로고
    • Aggravation of left ventricular remodeling by a novel specific endothelin ET(A) antagonist EMD94246 in rats with experimental myocardial infarction
    • Hu K, Gaudron P, Schmidt TJ, et al. Aggravation of left ventricular remodeling by a novel specific endothelin ET(A) antagonist EMD94246 in rats with experimental myocardial infarction. J Cardiovasc Pharmacol. 1998;32:505-508.
    • (1998) J Cardiovasc Pharmacol , vol.32 , pp. 505-508
    • Hu, K.1    Gaudron, P.2    Schmidt, T.J.3
  • 90
    • 18344385479 scopus 로고    scopus 로고
    • Early intervention with a potent endothelin-A/endothelin-B receptor antagonist aggravates left ventricular remodeling after myocardial infarction in rats
    • Oie E, Yndestad A, Robins SP, et al. Early intervention with a potent endothelin-A/endothelin-B receptor antagonist aggravates left ventricular remodeling after myocardial infarction in rats. Basic Res Cardiol. 2002;97:239-247.
    • (2002) Basic Res Cardiol , vol.97 , pp. 239-247
    • Oie, E.1    Yndestad, A.2    Robins, S.P.3
  • 91
    • 0034691270 scopus 로고    scopus 로고
    • Long-term endothelin receptor antagonist administration improves alterations in expression of various cardiac genes in failing myocardium of rats with heart failure
    • Sakai S, Miyauchi T, Yamaguchi I. Long-term endothelin receptor antagonist administration improves alterations in expression of various cardiac genes in failing myocardium of rats with heart failure. Circulation. 2000;101:2849-2853.
    • (2000) Circulation , vol.101 , pp. 2849-2853
    • Sakai, S.1    Miyauchi, T.2    Yamaguchi, I.3
  • 92
    • 19944394185 scopus 로고    scopus 로고
    • Chronic administration of an endothelin- A receptor antagonist improves exercise capacity in rats with myocardial infarction-induced congestive heart failure
    • Miyauchi T, Fujimori A, Maeda S, et al. Chronic administration of an endothelin- A receptor antagonist improves exercise capacity in rats with myocardial infarction-induced congestive heart failure. J Cardiovasc Pharmacol. 2004;44(suppl 1):S64-S67.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.SUPPL. 1
    • Miyauchi, T.1    Fujimori, A.2    Maeda, S.3
  • 93
    • 0034971752 scopus 로고    scopus 로고
    • ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat
    • Podesser BK, Siwik DA, Eberli FR, et al. ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat. Am J Physiol Heart Circ Physiol. 2001;280:H984-H991.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Podesser, B.K.1    Siwik, D.A.2    Eberli, F.R.3
  • 94
    • 0036220503 scopus 로고    scopus 로고
    • Cardioprotection by longterm ET(A) receptor blockade and ACE inhibition in rats with congestive heart failure: Mono- versus combination therapy
    • Fraccarollo D, Bauersachs J, Kellner M, et al. Cardioprotection by longterm ET(A) receptor blockade and ACE inhibition in rats with congestive heart failure: mono- versus combination therapy. Cardiovasc Res. 2002;54:85-94.
    • (2002) Cardiovasc Res , vol.54 , pp. 85-94
    • Fraccarollo, D.1    Bauersachs, J.2    Kellner, M.3
  • 95
    • 0029918005 scopus 로고    scopus 로고
    • Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart
    • Sakai S, Miyauchi T, Sakurai T, et al. Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart. Circulation. 1996;93:1214-1222.
    • (1996) Circulation , vol.93 , pp. 1214-1222
    • Sakai, S.1    Miyauchi, T.2    Sakurai, T.3
  • 96
    • 11044237893 scopus 로고    scopus 로고
    • Endothelin-1 gene polymorphism in patients with malignant arrhythmias
    • Kozák M, Izákovicová Hollá L, Krivan L, et al. Endothelin-1 gene polymorphism in patients with malignant arrhythmias. J Cardiovasc Pharmacol. 2004;44(suppl 1):S92-S95.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.SUPPL. 1
    • Kozák, M.1    Izákovicová Hollá, L.2    Krivan, L.3
  • 97
    • 1642453774 scopus 로고    scopus 로고
    • Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice
    • Yang LL, Gros R, Kabir MG, et al. Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice. Circulation. 2004;109:255-261.
    • (2004) Circulation , vol.109 , pp. 255-261
    • Yang, L.L.1    Gros, R.2    Kabir, M.G.3
  • 98
    • 79551490742 scopus 로고    scopus 로고
    • Electrical remodelling precedes heart failure in an endothelin-1-induced model of cardiomyopathy
    • Mueller EE, Momen A, Massé S, et al. Electrical remodelling precedes heart failure in an endothelin-1-induced model of cardiomyopathy. Cardiovasc Res. 2011;89:623-633.
    • (2011) Cardiovasc Res , vol.89 , pp. 623-633
    • Mueller, E.E.1    Momen, A.2    Massé, S.3
  • 99
    • 33744925913 scopus 로고    scopus 로고
    • Beneficial cardiovascular effects of endothelin ET(A) receptor blockade in established long-term heart failure after myocardial infarction
    • Vetter D, Shaw SG, Brandes RP, et al. Beneficial cardiovascular effects of endothelin ET(A) receptor blockade in established long-term heart failure after myocardial infarction. Exp Biol Med (Maywood). 2006;231:857-860.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 857-860
    • Vetter, D.1    Shaw, S.G.2    Brandes, R.P.3
  • 100
    • 0032543936 scopus 로고    scopus 로고
    • Short-term haemodynamic effects of BQ-123 a selective endothelin ET(A)-receptor antagonist in chronic heart failure
    • Cowburn PJ, Cleland JG, McArthur JD, et al. Short-term haemodynamic effects of BQ-123, a selective endothelin ET(A)-receptor antagonist, in chronic heart failure. Lancet. 1998;352:201-202.
    • (1998) Lancet , vol.352 , pp. 201-202
    • Cowburn, P.J.1    Cleland, J.G.2    McArthur, J.D.3
  • 101
    • 0029087262 scopus 로고
    • Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure
    • Kiowski W, Sütsch G, Hunziker P, et al. Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet. 1995;346:732-736.
    • (1995) Lancet , vol.346 , pp. 732-736
    • Kiowski, W.1    Sütsch, G.2    Hunziker, P.3
  • 102
    • 33846221367 scopus 로고    scopus 로고
    • Clinical trials of endothelin antagonists in heart failure: Publication is good for the public health
    • Kelland NF, Webb DJ. Clinical trials of endothelin antagonists in heart failure: publication is good for the public health. Heart. 2007;93:2-4.
    • (2007) Heart , vol.93 , pp. 2-4
    • Kelland, N.F.1    Webb, D.J.2
  • 103
    • 40949132561 scopus 로고    scopus 로고
    • The endothelin system as a therapeutic target in cardiovascular disease: Great expectations or bleak house?
    • Kirkby NS, Hadoke PW, Bagnall AJ, et al. The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? Br J Pharmacol. 2008;153:1105-1119.
    • (2008) Br J Pharmacol , vol.153 , pp. 1105-1119
    • Kirkby, N.S.1    Hadoke, P.W.2    Bagnall, A.J.3
  • 104
    • 84867578602 scopus 로고    scopus 로고
    • Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve?
    • Kohan DE, Cleland JG, Rubin LJ, et al. Clinical trials with endothelin receptor antagonists: what went wrong and where can we improve? Life Sci. 2012;91:528-539.
    • (2012) Life Sci , vol.91 , pp. 528-539
    • Kohan, D.E.1    Cleland, J.G.2    Rubin, L.J.3
  • 105
    • 84855474159 scopus 로고    scopus 로고
    • Endothelin antagonists in clinical trials: Lessons learned
    • Barton M, Kohan DE. Endothelin antagonists in clinical trials: lessons learned. Contrib Nephrol. 2011;172:255-260.
    • (2011) Contrib Nephrol , vol.172 , pp. 255-260
    • Barton, M.1    Kohan, D.E.2


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