Collagen accumulation after myocardial infarction: Effects of ETA receptor blockade and implications for early remodeling

Cardiovascular Research

Volumn 54, Issue 3, 2002, Pages 559-567

  Fraccarollo, Daniela ^a,b   Galuppo, Paolo ^a   Bauersachs, Johann ^a   Ertl, Georg ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

Endothelins; Extracellular matrix; Gene expression; Infarction; Remodeling

Indexed keywords

COLLAGEN; COLLAGEN TYPE 2; COLLAGEN TYPE 3; COLLAGENASE 3; DARUSENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; GELATINASE A; PLACEBO; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CORONARY ARTERY LIGATION; FEMALE; GENE EXPRESSION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE CONTRACTION; HEMODYNAMICS; MORPHOMETRICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; SCAR FORMATION; TISSUE LEVEL; TISSUE REPAIR; WESTERN BLOTTING;

EID: 0036272196     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00256-0     Document Type: Article

References (44)

1. Infarct scar: A dynamic tissue
2. Regulation of collagen degradation in the rat myocardium after infarction
3. Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat
4. Collagen remodeling after myocardial infarction in the rat heart
5. Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin
6. Role of collagen in acute myocardial infarct expansion
7. Effect of captopril and enalapril on left ventricular geometry, function and collagen during healing after anterior and inferior myocardial infarction in a dog model
8. Monitoring tissue repair and fibrosis from a distance
9. Extracellular matrix remodeling in heart failure: A role for de novo angiotensin II generation
10. Effects of endothelins on collagen turnover in cardiac fibroblasts
11. Selective ETA receptor blockade prevents left ventricular remodeling and deterioration of cardiac function in experimental heart failure
12. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure
13. Aggravation of left ventricular remodeling by a novel specific endothelin ET(A) antagonist EMD94246 in rats with experimental myocardial infarction
14. Endothelin A receptor blockade causes adverse left ventricular remodeling but improves pulmonary artery pressure after infarction in the rat
15. Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: Possible involvement of myocardial endothelin system in ventricular remodeling
16. Steroid administration after myocardial infarction promotes early infarct expansion
17. Aspirin enhances the benefits of late reperfusion on infarct shape. A possible mechanism of the beneficial effects of aspirin on survival after acute myocardial infarction
18. Advanced glycation end products: Activators of cardiac remodeling in primary fibroblasts from adult rat hearts
19. Quantitative zymography: Detection of picogram quantities of gelatinases
20. Quantitative reverse zymography: Analysis of picogram amounts of metalloproteinase inhibitors using gelatinase A and B reverse zymograms
21. Determination of hydroxyproline
22. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications
23. Differential effects of transforming growth factor-beta 1 and phorbol myristate acetate on cardiac fibroblasts. Regulation of fibrillar collagen mRNAs and expression of early transcription factors
24. Myocardial fibrosis in DOCA-salt hypertensive rats: Effect of endothelin ET(A) receptor antagonism
25. Nitric oxide inhibition induces early activation of type I collagen gene in renal resistance vessels and glomeruli in transgenic mice. Role of endothelin
26. Pulmonary and cardiac expression of preproendothelin-1 mRNA are increased in heart failure after myocardial infarction in rats. Localization of preproendothelin-1 mRNA and endothelin peptide
27. Unravelling the mysteries of collagen and cicatrix after myocardial infarction
28. Cellular mechanisms of myocardial infarct expansion
29. Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats
30. Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling
31. Remodeling of human myocardial collagen in idiopathic dilated cardiomyopathy. Role of metalloproteinases and pyridinoline cross-links
32. Post-transcriptional regulation of extracellular matrix metalloproteinase in human heart end-stage failure secondary to ischemic cardiomyopathy
33. TIMP-2 is required for efficient activation of proMMP-2 in vivo
34. The role of matrix metalloproteinases in heart disease
35. Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice
36. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
37. Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction
38. Structural basis of end-stage failure in ischemic cardiomyopathy in humans
39. Myocardial extracellular matrix remodeling in transgenic mice over-expressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy
40. ET(A)-receptor blockade prevents matrix metalloproteinase activation late post-myocardial infarction in the rat
41. Cardioprotection by long-term ETA receptor blockade and ACE inhibition in rats with congestive heart failure: Mono- versus combination therapy
42. Echocardiography-derived left ventricular end-systolic regional wall stress and matrix remodeling after experimental myocardial infarction
43. Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure
44. Fibroblast matrix gene expression and connective tissue remodeling: Role of endothelin-1