Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries

Circulation

Volumn 104, Issue 10, 2001, Pages 1114-1118

  Kinlay, Scott ^a   Behrendt, Dominik ^a   Wainstein, Marco ^a   Beltrame, John ^a   Fang, James C ^a   Creager, Mark A ^a   Selwyn, Andrew P ^a   Ganz, Peter ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Atherosclerosis; Endothelin; Endothelium; Vasoconstriction

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; GLYCERYL TRINITRATE;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY TONE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY OBSTRUCTION; HUMAN; INTRACORONARY INFUSION; PRIORITY JOURNAL;

EID: 0035806922     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc3501.095707     Document Type: Article

References (33)

1. The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress
2. Paradoxical narrowing of atherosclerotic coronary arteries induced by increases in heart rate
3. Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test
4. Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise
5. Local coronary supersensitivity to diverse vasoconstrictive stimuli in patients with variant angina
6. Relation between endothelial dysfunction and the acute coronary syndrome: Implications for therapy
7. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries
8. Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis
9. Endothelin-1 and endothelin receptor mRNA expression in normal and atherosclerotic human arteries
10. Tissue endothelin-1 immunoreactivity in the active coronary atherosclerotic plaque: A clue to the mechanism of increased vasoreactivity of the culprit lesion in unstable angina
11. Endothelin-1 as a mediator in cardiovascular disease
12. Endothelins: An overview of recent achievements
13. B receptors cause vasoconstriction of human resistance and capacitance vessels in vivo
14. Role of endothelin in the increased vascular tone of patients with essential hypertension
15. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade
16. Endothelin ETA and ETB mRNA and receptors expressed by smooth muscle in the human vasculature: Majority of the ETA sub-type
17. Measurement of coronary sinus blood flow by continuous thermodilution in man
18. Vasoconstriction to endogenous endothelin-1 is increased in the peripheral circulation of patients with essential hypertension
19. Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor
20. Contribution of endogenous generation of endothelin-1 to basal vascular tone
21. Endothelins, peptides with potent vasoactive properties, are produced by human macrophages
22. Effect of cytokines on the production of endothelin by endothelial cells
23. Modified low density lipoproteins activate human macrophages to secrete immunoreactive endothelin
24. Granulocyte-macrophage colonystimulating factor and interleukin-3 potentiate interferon-gamma mediated endothelin production by human monocytes: Role of protein kinase C
25. Secretion of endothelin-1 and endothelin-3 by human cultured vascular smooth muscle cells
26. Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: Evidence for intracellular endothelin-converting enzyme
27. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
28. Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines
29. Role of thromboxane and serotonin as mediators in the development of spontaneous alterations in coronary blood flow and neointimal proliferation in canine models with chronic coronary artery stenoses and endothelial injury
30. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction
31. Nitric oxide activity in the atherosclerotic human coronary circulation
32. Modulation of coronary vasomotor tone in humans: Progressive endothelial dysfunction with different early stages of coronary atherosclerosis
33. The physiological role of endogenous endothelin in the regulation of human coronary vasomotor tone