Oxidative stress increases endothelin-1 synthesis in human coronary artery smooth muscle cells

Journal of Cardiovascular Pharmacology

Volumn 38, Issue 1, 2001, Pages 49-57

  Kähler, Jan ^a   Ewert, Anne ^a   Weckmüller, Jörn ^a   Stobbe, Silvia ^a   Mittmann, Clemens ^a   Köster, Ralf ^a   Paul, Martin ^b   Meinertz, Thomas ^a   Münzel, Thomas ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Endothelins; Nitric oxide; Oxygen derived radicals; Vascular smooth muscle cells

Indexed keywords

CATALASE; ENDOTHELIN 1; HYDROGEN PEROXIDE; MESSENGER RNA; OXYGEN RADICAL; SUPEROXIDE DISMUTASE; XANTHINE; XANTHINE OXIDASE;

ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA ANALYSIS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

CELLS, CULTURED; CORONARY VESSELS; ENDOTHELIN-1; HUMANS; HYDROGEN PEROXIDE; MUSCLE, SMOOTH, VASCULAR; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; XANTHINE OXIDASE;

EID: 0034943021     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200107000-00006     Document Type: Article

References (24)

1. Cellular mechanism of thrombin on endothelin-1 biosynthesis and release in bovine endothelial cells
2. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells
3. Effect of reactive oxygen species on endothelin-1 production by human mesangial cells
4. Oxidant stress regulates basal endothelin-1 production by cultured rat pulmonary endothelial cells
5. Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter
6. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
7. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
8. Activation of mitogen-activated protein kinase
9. Endothelial dysfunction in atherosclerosis
10. Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction
11. The human preproendothelin-1 gene
12. Evidence for enhanced vascular superoxide anion production in nitrate tolerance
13. Does superoxide underlie the pathogenesis of hypertension?
14. Cyclic strain induces an oxidative stress in endothelial cells
15. Reduced endothelin-1 secretion by pulmonary vascular endothelial-cells exposed to hypoxanthine-xanthine oxidase
16. Oxidative stress suppresses the endothelial secretion of endothelin
17. Increased plasma endothelin-1 in pulmonary hypertension: Marker or mediator of disease?
18. Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance
19. Role for endothelin-1 in angiotensin II-mediated hypertension
20. In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats
21. Hypercholesterolemia increases endothelial superoxide anion production
22. Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation
23. S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells
24. Advanced glycation end product-induced activation of NF-kappa B is suppressed by alpha-lipoic acid in cultured endothelial cells