Endothelin-1 inhibits the slow component of cardiac delayed rectifier K+ currents via a pertussis toxin-sensitive mechanism

Circulation Research

Volumn 81, Issue 2, 1997, Pages 211-218

  Washizuka, Takashi ^a   Horie, Minoru ^a   Watanuki, Masato ^a   Sasayama, Shigetake ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Delayed rectifier K+ current; Endothelin A receptor; Endothelin 1; G protein; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; PERTUSSIS TOXIN;

ADOLESCENT; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; GUINEA PIG; HEART ELECTROPHYSIOLOGY; HEART FAILURE; HEART MUSCLE ISCHEMIA; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL;

EID: 0030798910     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.81.2.211     Document Type: Article

References (44)

1. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. Masaki T, Yanagisawa Y, Goto K. Physiology and pharmacology of endothelins. Med Res Rev. 1992;12:391-421.
3. Miyauchi T, Yanagisawa M, Tomizawa T, Sugishita Y, Suzuki N, Fujino M, Ajisaka R, Goto K, Masaki T. Increased plasma concentrations of endothelin-1 and big endothelin-l in acute myocardial infarction. Lancet. 1989;2:53-54.
4. Saitoh Y, Nakao K, Mukoyama M, Imura H. Increased plasma endothelin level in patients with essential hypertension. N Engl J Med. 1990;322:205.
5. Koseki C, Imai M, Hirata Y, Yanagisawa M, Masaki T. Autoradiographic distribution in rat tissues of binding sites for endothelin: a neuropeptide? Am J Physiol. 1989;256:R858-R866.
6. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature. 1990;348:730-732.
7. Sakurai T, Yanagisawa M, Takuma Ym Miyazaki H, Kimura S, Goto K, Masaki T. Cloning of a cDNA encoding a non-isopeptide-selcctive subtype of the endothelin receptor. Nature. 1990;348: 732-735.
8. Ishikawa T, Li L, Shinmi O, Kimura S, Yanagisawa M, Goto K, Masaki T. Characteristics of binding of endotltelin-1 and endothelin-3 to rat hearts: developmental changes in mechanical responses and receptor subtypes, Circ Res. 1991;69:918-926.
9. Ishikawa T, Yanagisawa M, Kimura S, Goto K, Masaki T. Positive chronotrophic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide. Pflugers Arch. 1988;413:108-110.
10. - conductance by endothelin-1. Nature. 1994;370:297-300.
11. - current via pertussis toxin-sensitive mechanism. Heart Vessels. 1995;59:83-85.
12. Jones LG, Rozich JD, Tsutsui H, Cooper G. Endothelin stimulates multiple responses in isolated adult ventricular cardiac myocytes. Am J Physiol. 1992;263:H1447-H1454.
13. Hilal-Danden RH, Urasawa K, Bruton LL. Endothelin inhibits adenylate cyclase and stimulates phosphoinositide hydrolysis in adult cardiac myocytes. J Biol Chem. 1992;267:10620-10624.
14. Joncs LG. Inhibition of cyclic AMP accumulation by endothelin is pertussis toxin sensitive and calcium independent in isolated adult Mine cardiac myocytes. Life Sci. 1996;58:115-123.
15. 2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes. J Physiol (Lond). 1992;448:729-747.
16. Furukawa T, Ito H, Nitta J, Tsujino M, Adachi S, Hirose M, Marumo F, Sawanobori T, Hiraoka M. Endothelin-1 enhances calcium entry through T-type calcium channels in cultured neonatal rat ventricular myocytes. Circ Res. 1992;71:1242-1253.
17. 2+ current in guinea-pig heart cells, Br J Pharmacol. 1990;99:437-438.
18. Xie L-H, Horie M, James AF, Watanuki M, Sasayama S. Endothelin-1 inhibits L-type Ca-currents enhanced by isoproterenol in guinea pig ventricular myocytes. Pflugers Arch. 1996;431: 533-539.
19. Ono K, Tsujimoto G, Sakamoto A, Eto K, Masaki T, Ozaki Y, Satake M. Endothelin-A receptor mediates cardiac inhibition by regulating calcium and potassium currents. Nature. 1994;370: 301-304.
20. + current in guinea pig heart cells. Am J Physiol. 1987;253:H1321-H1324.
21. Hartzell HC. Regulation of cardiac ion channels by catecholamines, acetylcholine. and second messenger system. Prog Biophys Mol Biol. 1988;52:165-247.
22. Walsh KB, Kass RS. Regulation of a heart potassium channel by protein kinase A and C. Science. 1988;242:67-69.
23. Yazawa K, Kameyama M. Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytes. J Physiol (Lond). 1990;421:135-150.
24. Sanguinetti MC, Jurkiewicz NK, Scott A, Siegl PKS. Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes: mechanism of action. Circ Res. 1991;68:77-84.
25. Habuchi Y, Tanaka H, Furukawa T, Tsujimura Y, Takahashi H, Yoshimura M. Endothelin enhances delayed potassium current via phospholipase C in guinea pig ventricular myocytes. Am J Physiol. 1992;262:H345-H354.
26. Sakai S, Miyauchi T, Kobayashi M, Yamaguchi I, Goto K, Sugishita Y. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure. Nature. 1996;384:353-355.
27. Hwang T-C, Horie M, Nairn AC, Gadsby DC. Roles of GTP-binding proteins in the regulation of cardiac chloride conductance. J Gen Physiol. 1992;99:465-489.
28. Isenberg G., Klöckner U. Calcium tolerant ventricular myocytes prepared by preincubation in a 'KB medium.' Pflugers Arch. 1982; 395:6-18.
29. Fabiato A, Fabiato F. Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J Physiol (Paris). 1979;75:463-505.
30. Tsien RY, Rink TJ. Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. Biochcm Biophys Acta. 1980;599:623-638.
31. Horn R, Marty A. Muscarinic activation of ionic currents measured by a new whole cell recording method. J Gen Physiol. 1988;92: 145-159.
32. Yawo H, Chuhma N. An improved method for perforated patch recordings using nystatin-fluorescein mixture. Jpn J Physiol. 1993; 43:267-273.
33. Harvey RD, Hume JR. Autonomic regulation of delayed rectifier K current in mammalian heart involves G proteins. Am J Physiol. 1989;257:H818-H823.
34. + current: differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol. 1990;96:195-215.
35. Rubanyi GM, Polokoff MA. Endothelins: molecular biology, biochemistry, pharmacology, and pathophysiology. Pharmacol Rev. 1994;46:325-415.
36. Sogabe K, Nirei H, Shoubo M, Nomoto A, Ao S, Yoshida N, Ono T. Pharmacological profile of FR-139317, a novel, potent endothelin ETA receptor antagonist. J Pharmacol Exp Ther. 1993;264: 1040-1046.
37. Simonson MS. Endothelins: multifunctional renal peptides. Physiol Rev. 1993;73:375-411.
38. Tanaka H, Furukawa T, Hayafuji M, Habuchi Y. Modulation of the delayed K current by histamine in guinea pig ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol. 1991;344:582-588.
39. Seamon KB, Daly JW. Forskolin: its biological and chemical properties. In: Greengard P, Robinson GA, eds. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 1986;20:1-150.
40. + current of guinea pig ventricular cells through the activation of protein kinase C. Circ Res. 1992;71: 1441-1446.
41. Yorikane R, Koike H, Miyake S. Electrophysiological effects of endothelin-1 on canine myocardial cells. J Candiovasc Pharmacol. 1991;17(suppl 7):S159-S162.
42. Merkely B, Miklos T, Solti F, Kekesi V, Kiss O, Vecsey T, Horkay F, Szokodi I, Tenezer I, Tenczer J, Juhasz-Nagy A. A new ventricular tachycardia model: endothelin-induced triggered arrhythmias in dogs. Circulation. 1995;92(.suppl 1): 1-641. Abstract.
43. Ezra D, Goldstein RB, Czala JF, Feuerstein GZ. Lethal ischemia due to intracoronary endotholin in pigs. Am J Physiol. 1989;257: H339-H343.
44. A-receptor antagonist, BQ-123, on ischemic arrhythmias in anesthetized rats. J Cardiovasc Pharmacol. 1995; 25:634-642.