Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 12, 2013, Pages 2996-3005

  Xiang, Lisha ^a   Xie, Ganfeng ^a   Liu, Chen ^a   Zhou, Jie ^a   Chen, Jianfang ^a   Yu, Songtao ^a   Li, Jianjun ^a   Pang, Xueli ^a   Shi, Hang ^b   Liang, Houjie ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Cervical cancer; Glutathione; Phosphate activated mitochondrial glutaminase; Radioresistance

Indexed keywords

GLUTAMINASE; GLUTAMINASE 2; GLUTATHIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER PATIENT; CANCER SURGERY; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; IRRADIATION; MOUSE; MULTIMODALITY CANCER THERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; RADIATION RESPONSE; RADIOSENSITIVITY; RADIOSENSITIZATION; TREATMENT FAILURE; TUMOR XENOGRAFT; UTERINE CERVIX CANCER; WESTERN BLOTTING; X RAY;

EID: 84883407636     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.08.003     Document Type: Article

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