Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5

Journal of Biological Chemistry

Volumn 288, Issue 35, 2013, Pages 25244-25253

  Lee, Sei Jung ^a   No, Yi Ran ^a   Dang, Duyen T ^b   Dang, Long H ^c   Yang, Vincent W ^d   Shim, Hyunsuk ^a,e   Yun, C Chris ^a,e  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d STONY BROOK UNIVERSITY   (United States)

^e EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLON CANCER; HYPOXIA-INDUCIBLE FACTOR 1; LYSOPHOSPHATIDIC ACID; NEW DIMENSIONS;

BIOCHEMISTRY; BIOLOGY;

PHOSPHOLIPIDS;

HYPOXIA INDUCIBLE FACTOR 1ALPHA; KRUPPEL LIKE FACTOR 5; LYSOPHOSPHATIDIC ACID; PROTEIN MDM2; PROTEIN P53; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CHROMATIN IMMUNOPRECIPITATION; COLON CANCER; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; HIF 1ALPHA GENE; HUMAN; HUMAN CELL; KLF5 GENE; LOSS OF FUNCTION MUTATION; MDM2 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

COLON CANCER; G PROTEIN-COUPLED RECEPTOR (GPCR); HYPOXIA-INDUCIBLE FACTOR (HIF); LYSOPHOSPHOLIPID; PROLIFERATION;

CELL LINE, TUMOR; COLONIC NEOPLASMS; GENE SILENCING; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LYSOPHOSPHOLIPIDS; MUTATION; PROTEIN BINDING; RESPONSE ELEMENTS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84883313474     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.489708     Document Type: Article

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