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Volumn 66, Issue 16, 2006, Pages 7983-7990

Hypoxia enhances lysophosphatidic acid responsiveness in ovarian cancer cells and lysophosphatidic acid induces ovarian tumor metastasis in vivo

Author keywords

[No Author keywords available]

Indexed keywords

17 DIMETHYLAMINOETHYLAMINO 17 DEMETHOXYGELDANAMYCIN; COLLAGEN TYPE 1; GELDANAMYCIN; HEAT SHOCK PROTEIN 90 INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LYSOPHOSPHATIDIC ACID; PHOSPHOLIPASE A2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 33748056087     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-4381     Document Type: Article
Times cited : (126)

References (47)
  • 2
    • 10644247638 scopus 로고    scopus 로고
    • Promising directions for the diagnosis and management of gynecological cancers
    • Kohn EC, Mills GB, Liotta L. Promising directions for the diagnosis and management of gynecological cancers. Int J Gynaecol Obstet 2003;83 Suppl 1:203-9.
    • (2003) Int J Gynaecol Obstet , vol.83 , Issue.SUPPL. 1 , pp. 203-209
    • Kohn, E.C.1    Mills, G.B.2    Liotta, L.3
  • 3
    • 0037271783 scopus 로고    scopus 로고
    • Specific keynote: Molecular therapeutics in ovarian cancer
    • discussion S93-86
    • Mills GB, Fang X, Lu Y, et al. Specific keynote: molecular therapeutics in ovarian cancer. Gynecol Oncol 2003;88:S88-92;discussion S93-86.
    • (2003) Gynecol Oncol , vol.88
    • Mills, G.B.1    Fang, X.2    Lu, Y.3
  • 7
    • 0029010592 scopus 로고
    • Expression of cell adhesion molecules on ovarian tumour cell lines and mesothelial cells, in relation to ovarian cancer metastasis
    • Gardner MJ, Jones LM, Catterall JB, Turner GA. Expression of cell adhesion molecules on ovarian tumour cell lines and mesothelial cells, in relation to ovarian cancer metastasis. Cancer Lett 1995;91:229-34.
    • (1995) Cancer Lett , vol.91 , pp. 229-234
    • Gardner, M.J.1    Jones, L.M.2    Catterall, J.B.3    Turner, G.A.4
  • 8
    • 0029126484 scopus 로고
    • Lysophospholipids activate ovarian and breast cancer cells
    • Xu Y, Fang XJ, Casey G, Mills GB. Lysophospholipids activate ovarian and breast cancer cells. Biochem J 1995;309:933-40.
    • (1995) Biochem J , vol.309 , pp. 933-940
    • Xu, Y.1    Fang, X.J.2    Casey, G.3    Mills, G.B.4
  • 9
    • 0028871499 scopus 로고
    • Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients
    • Xu Y, Gaudette DC, Boynton JD, et al. Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients. Clin Cancer Res 1995;1:1223-32.
    • (1995) Clin Cancer Res , vol.1 , pp. 1223-1232
    • Xu, Y.1    Gaudette, D.C.2    Boynton, J.D.3
  • 12
    • 0042887042 scopus 로고    scopus 로고
    • The emerging role of lysophosphatidic acid in cancer
    • Mills GB, Moolenaar WH. The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer 2003;3:582-91.
    • (2003) Nat Rev Cancer , vol.3 , pp. 582-591
    • Mills, G.B.1    Moolenaar, W.H.2
  • 13
    • 0942301169 scopus 로고    scopus 로고
    • Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2)
    • Huang MC, Lee HY, Yeh CC, Kong Y, Zaloudek CJ, Goetzl EJ. Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2). Oncogene 2004;23:122-9.
    • (2004) Oncogene , vol.23 , pp. 122-129
    • Huang, M.C.1    Lee, H.Y.2    Yeh, C.C.3    Kong, Y.4    Zaloudek, C.J.5    Goetzl, E.J.6
  • 14
    • 0042704741 scopus 로고    scopus 로고
    • A novel laminin-induced LPA autocrme loop in the migration of ovarian cancer cells
    • Sengupta S, Xiao YJ, Xu Y. A novel laminin-induced LPA autocrme loop in the migration of ovarian cancer cells. FASEB J 2003;17:1570-2.
    • (2003) FASEB J , vol.17 , pp. 1570-1572
    • Sengupta, S.1    Xiao, Y.J.2    Xu, Y.3
  • 15
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 18
    • 0028948002 scopus 로고
    • The significance of urokinase-type plasminogen activator, its inhibitors, and its receptor in ascites of patients with epithelial ovarian cancer
    • Chambers SK, Gertz RE, Jr., Ivins CM, Kacinski BM. The significance of urokinase-type plasminogen activator, its inhibitors, and its receptor in ascites of patients with epithelial ovarian cancer. Cancer 1995;75:1627-33.
    • (1995) Cancer , vol.75 , pp. 1627-1633
    • Chambers, S.K.1    Gertz Jr., R.E.2    Ivins, C.M.3    Kacinski, B.M.4
  • 19
    • 0035025317 scopus 로고    scopus 로고
    • Lysophospholipids increase interleukin-8 expression in ovarian cancer cells
    • Schwartz BM, Hong G, Morrison BH, et al. Lysophospholipids increase interleukin-8 expression in ovarian cancer cells. Gynecol Oncol 2001;81:291-300.
    • (2001) Gynecol Oncol , vol.81 , pp. 291-300
    • Schwartz, B.M.1    Hong, G.2    Morrison, B.H.3
  • 20
    • 0035897531 scopus 로고    scopus 로고
    • Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells
    • Hu YL, Tee MK, Goetzl EJ, et al. Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells. J Natl Cancer Inst 2001;93:762-8.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 762-768
    • Hu, Y.L.1    Tee, M.K.2    Goetzl, E.J.3
  • 21
    • 0032712996 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells
    • Pustilnik TB, Estrella V, Wiener JR, et al. Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells. Clin Cancer Res 1999;5:3704-10.
    • (1999) Clin Cancer Res , vol.5 , pp. 3704-3710
    • Pustilnik, T.B.1    Estrella, V.2    Wiener, J.R.3
  • 22
    • 10744225477 scopus 로고    scopus 로고
    • Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells
    • Fang X, Yu S, Bast RC, et al. Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells. J Biol Chem 2004;279:9653-61.
    • (2004) J Biol Chem , vol.279 , pp. 9653-9661
    • Fang, X.1    Yu, S.2    Bast, R.C.3
  • 23
    • 0024411016 scopus 로고
    • A new in vitro assay for quantitating tumor cell invasion
    • Repesh LA. A new in vitro assay for quantitating tumor cell invasion. Invasion Metastasis 1989;9:192-208.
    • (1989) Invasion Metastasis , vol.9 , pp. 192-208
    • Repesh, L.A.1
  • 24
    • 0036208331 scopus 로고    scopus 로고
    • Role of ether-linked lysophosphatidic acids in ovarian cancer cells
    • Lu J, Xiao YJ, Baudhuin LM, Hong G, Xu Y. Role of ether-linked lysophosphatidic acids in ovarian cancer cells. J Lipid Res 2002;43:463-76.
    • (2002) J Lipid Res , vol.43 , pp. 463-476
    • Lu, J.1    Xiao, Y.J.2    Baudhuin, L.M.3    Hong, G.4    Xu, Y.5
  • 25
    • 33645525087 scopus 로고    scopus 로고
    • Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration and invasion of ovarian cancer cells
    • Ren J, Xiao XJ, Singh LS, et al. Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration and invasion of ovarian cancer cells. Cancer Res 2006;66:3006-14.
    • (2006) Cancer Res , vol.66 , pp. 3006-3014
    • Ren, J.1    Xiao, X.J.2    Singh, L.S.3
  • 26
    • 0036569704 scopus 로고    scopus 로고
    • Geldanamycin induces degradation of hypoxia-inducible factor 1α protein via the proteosome pathway in prostate cancer cells
    • Mabjeesh NJ, Post DE, Willard MT, et al. Geldanamycin induces degradation of hypoxia-inducible factor 1α protein via the proteosome pathway in prostate cancer cells. Cancer Res 2002;62:2478-82.
    • (2002) Cancer Res , vol.62 , pp. 2478-2482
    • Mabjeesh, N.J.1    Post, D.E.2    Willard, M.T.3
  • 27
    • 0034532066 scopus 로고    scopus 로고
    • Modulation of metastasis phenotypes of non-small cell lung cancer cells by 17-allylamino 17-demethoxy geldanamycin
    • Nguyen DM, Desai S, Chen A, Weiser TS, Schrump DS. Modulation of metastasis phenotypes of non-small cell lung cancer cells by 17-allylamino 17-demethoxy geldanamycin. Ann Thorac Surg 2000;70:1853-60.
    • (2000) Ann Thorac Surg , vol.70 , pp. 1853-1860
    • Nguyen, D.M.1    Desai, S.2    Chen, A.3    Weiser, T.S.4    Schrump, D.S.5
  • 28
    • 0033566822 scopus 로고    scopus 로고
    • Effects of geldanamycin on signaling through activator-protein 1 in hypoxic HT29 human colon adenocarcinoma cells
    • Vasilevskaya IA, O'Dwyer PJ. Effects of geldanamycin on signaling through activator-protein 1 in hypoxic HT29 human colon adenocarcinoma cells. Cancer Res 1999;59:3935-40.
    • (1999) Cancer Res , vol.59 , pp. 3935-3940
    • Vasilevskaya, I.A.1    O'Dwyer, P.J.2
  • 30
    • 0035869447 scopus 로고    scopus 로고
    • Electrospray ionization mass spectrometry analysis of lysophospholipids in human ascitic fluids: Comparison of the lysophospholipid contents in malignant vs nonmalignant ascitic fluids
    • Xiao YJ, Schwartz B, Washington M, et al. Electrospray ionization mass spectrometry analysis of lysophospholipids in human ascitic fluids: comparison of the lysophospholipid contents in malignant vs nonmalignant ascitic fluids. Anal Biochem 2001;290:302-13.
    • (2001) Anal Biochem , vol.290 , pp. 302-313
    • Xiao, Y.J.1    Schwartz, B.2    Washington, M.3
  • 31
    • 0034015340 scopus 로고    scopus 로고
    • Evaluation of plasma lysophospholipids for diagnostic significance using electrospray ionization mass spectrometry (ESI-MS) analyses
    • Xiao Y, Chen Y, Kennedy AW, Belinson J, Xu Y. Evaluation of plasma lysophospholipids for diagnostic significance using electrospray ionization mass spectrometry (ESI-MS) analyses. Ann N Y Acad Sci 2000;905:242-59.
    • (2000) Ann N Y Acad Sci , vol.905 , pp. 242-259
    • Xiao, Y.1    Chen, Y.2    Kennedy, A.W.3    Belinson, J.4    Xu, Y.5
  • 32
    • 0032414989 scopus 로고    scopus 로고
    • A patient-like orthotopic implantation nude mouse model of highly metastatic human ovarian cancer
    • Kiguchi K, Kubota T, Aoki D, et al. A patient-like orthotopic implantation nude mouse model of highly metastatic human ovarian cancer. Clin Exp Metastasis 1998;16:751-6.
    • (1998) Clin Exp Metastasis , vol.16 , pp. 751-756
    • Kiguchi, K.1    Kubota, T.2    Aoki, D.3
  • 33
    • 0034083409 scopus 로고    scopus 로고
    • Constitutive and lysophosphatidic acid (LPA)-induced LPA production: Role of phospholipase D and phospholipase A2
    • Eder AM, Sasagawa T, Mao M, Aoki J, Mills GB. Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2. Clin Cancer Res 2000;6:2482-91.
    • (2000) Clin Cancer Res , vol.6 , pp. 2482-2491
    • Eder, A.M.1    Sasagawa, T.2    Mao, M.3    Aoki, J.4    Mills, G.B.5
  • 34
    • 0035793032 scopus 로고    scopus 로고
    • The role and clinical applications of bioactive lysolipids in ovarian cancer
    • Xu Y, Xiao YJ, Baudhuin LM, Schwartz BM. The role and clinical applications of bioactive lysolipids in ovarian cancer. J Soc Gynecol Investig 2001;8:1-13.
    • (2001) J Soc Gynecol Investig , vol.8 , pp. 1-13
    • Xu, Y.1    Xiao, Y.J.2    Baudhuin, L.M.3    Schwartz, B.M.4
  • 35
    • 0024435434 scopus 로고
    • Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy
    • Massazza G, Tomasini A, Lucchini V, et al. Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy. Int J Cancer 1989;44:494-500.
    • (1989) Int J Cancer , vol.44 , pp. 494-500
    • Massazza, G.1    Tomasini, A.2    Lucchini, V.3
  • 36
    • 0034100051 scopus 로고    scopus 로고
    • In viro and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002)
    • Hu L, Zaloudek C, Mills GB, Gray J, Jaffe RB. In viro and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002). Clin Cancer Res 2000;6:880-6.
    • (2000) Clin Cancer Res , vol.6 , pp. 880-886
    • Hu, L.1    Zaloudek, C.2    Mills, G.B.3    Gray, J.4    Jaffe, R.B.5
  • 37
    • 21244462689 scopus 로고    scopus 로고
    • In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17- demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative
    • Hollingshead M, Alley M, Burger AM, et al. In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative. Cancer Chemother Pharmacol 2005;56:115-25.
    • (2005) Cancer Chemother Pharmacol , vol.56 , pp. 115-125
    • Hollingshead, M.1    Alley, M.2    Burger, A.M.3
  • 38
    • 0036867668 scopus 로고    scopus 로고
    • Importance of hypoxia in the biology and treatment of brain tumors
    • Knisely JP, Rockwell S. Importance of hypoxia in the biology and treatment of brain tumors. Neuroimaging Clin N Am 2002;12:525-36.
    • (2002) Neuroimaging Clin N Am , vol.12 , pp. 525-536
    • Knisely, J.P.1    Rockwell, S.2
  • 39
    • 0037134949 scopus 로고    scopus 로고
    • Plasma lysophosphatidic acid concentration and ovarian cancer
    • Baker DL, Morrison P, Miller B, et al. Plasma lysophosphatidic acid concentration and ovarian cancer. JAMA 2002;287:3081-2.
    • (2002) JAMA , vol.287 , pp. 3081-3082
    • Baker, D.L.1    Morrison, P.2    Miller, B.3
  • 40
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-32.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 41
    • 0141484615 scopus 로고    scopus 로고
    • A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
    • Kamal A, Thao L, Sensintaffar J, et al. A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003;425:407-10.
    • (2003) Nature , vol.425 , pp. 407-410
    • Kamal, A.1    Thao, L.2    Sensintaffar, J.3
  • 42
    • 16644387827 scopus 로고    scopus 로고
    • Hot topics in phospholipase A2 field
    • Murakami M. Hot topics in phospholipase A2 field. Biol Pharm Bull 2004;27:1179-82.
    • (2004) Biol Pharm Bull , vol.27 , pp. 1179-1182
    • Murakami, M.1
  • 43
    • 0028930542 scopus 로고
    • Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a p42 mitogen-activated protein kinase-dependent phosphorylation pathway in endothelial cells
    • Sa G, Murugesan G, Jaye M, Ivashchenko Y, Fox PL. Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a p42 mitogen-activated protein kinase-dependent phosphorylation pathway in endothelial cells. J Biol Chem 1995;270:2360-6.
    • (1995) J Biol Chem , vol.270 , pp. 2360-2366
    • Sa, G.1    Murugesan, G.2    Jaye, M.3    Ivashchenko, Y.4    Fox, P.L.5
  • 44
    • 0242526758 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate effect on endothelial cell PAF synthesis: Role in cellular migration
    • Bernatchez PN, Tremblay F, Rollin S, Neagoe PE, Sirois MG. Sphingosine 1-phosphate effect on endothelial cell PAF synthesis: role in cellular migration. J Cell Biochem 2003;90:719-31.
    • (2003) J Cell Biochem , vol.90 , pp. 719-731
    • Bernatchez, P.N.1    Tremblay, F.2    Rollin, S.3    Neagoe, P.E.4    Sirois, M.G.5
  • 45
    • 0029090375 scopus 로고
    • Clara cell protein (CC-16) induces a phospholipase A2-mediated inhibition of fibroblast migration in vitro
    • Lesur O, Bernard A, Arsalane K, et al. Clara cell protein (CC-16) induces a phospholipase A2-mediated inhibition of fibroblast migration in vitro. Am J Respir Crit Care Med 1995;152:290-7.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 290-297
    • Lesur, O.1    Bernard, A.2    Arsalane, K.3
  • 46
    • 0037308080 scopus 로고    scopus 로고
    • Norepinephrine-induced stimulation of p38 mitogen-activated protein kinase is mediated by arachidonic acid metabolites generated by activation of cytosolic phospholipase A(2) in vascular smooth muscle cells
    • Kalyankrishna S, Malik KU. Norepinephrine-induced stimulation of p38 mitogen-activated protein kinase is mediated by arachidonic acid metabolites generated by activation of cytosolic phospholipase A(2) in vascular smooth muscle cells. J Pharmacol Exp Ther 2003;304:761-72.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 761-772
    • Kalyankrishna, S.1    Malik, K.U.2
  • 47
    • 13244283216 scopus 로고    scopus 로고
    • STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility
    • Dronadula N, Liu Z, Wang C, Cao H, Rao GN. STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility. J Biol Chem 2005;280:3112-20.
    • (2005) J Biol Chem , vol.280 , pp. 3112-3120
    • Dronadula, N.1    Liu, Z.2    Wang, C.3    Cao, H.4    Rao, G.N.5


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