Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis

Cell Cycle

Volumn 12, Issue 16, 2013, Pages 2691-2702

  Rady, Brian ^a,b   Chen, Yanmei ^b   Vaca, Pilar ^b   Wang, Qian ^a,b   Wang, Yong ^a,b   Salmon, Patrick ^c   Oberholzer, José ^a,b  

^a University of Illinois at Chicago   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Beta cell proliferation; Beta cell replication; Cell cycle; E2F; E2F3; Insulinlin secreting cells; Insulinoma; Islet transplant; Type I diabetes

Indexed keywords

INSULIN; TRANSCRIPTION FACTOR E2F3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; INSULIN RELEASE; INSULINOMA; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; RAT;

MUS; RATTUS;

BETA-CELL PROLIFERATION; BETA-CELL REPLICATION; CELL CYCLE; E2F; E2F3; INSULIN-SECRETING CELLS; INSULINOMA; ISLET TRANSPLANT; TYPE I DIABETES;

ANALYSIS OF VARIANCE; ANIMALS; CELL PROLIFERATION; E2F3 TRANSCRIPTION FACTOR; HUMANS; IMMUNOBLOTTING; INSULIN-SECRETING CELLS; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSCOPY, FLUORESCENCE; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84883249699     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.25834     Document Type: Article

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