-
1
-
-
0033565915
-
Induction of antitumor immunity with dendritic cells transduced with adenovirus vector-encoding endogenous tumor-associated antigens
-
Kaplan J.M., Yu Q., Piraino S.T., Pennington S.E., Shankara S., Woodworth L.A., et al. Induction of antitumor immunity with dendritic cells transduced with adenovirus vector-encoding endogenous tumor-associated antigens. JImmunol 1999, 163:699-707.
-
(1999)
JImmunol
, vol.163
, pp. 699-707
-
-
Kaplan, J.M.1
Yu, Q.2
Piraino, S.T.3
Pennington, S.E.4
Shankara, S.5
Woodworth, L.A.6
-
2
-
-
12444262198
-
Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors
-
Okada N., Masunaga Y., Okada Y., Iiyama S., Mori N., Tsuda T., et al. Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors. Cancer Gene Ther 2003, 10:421-431.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 421-431
-
-
Okada, N.1
Masunaga, Y.2
Okada, Y.3
Iiyama, S.4
Mori, N.5
Tsuda, T.6
-
3
-
-
84874288984
-
Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia
-
Sundarasetty B.S., Singh V.K., Salguero G., Geffers R., Rickmann M., Macke L., et al. Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia. Hum Gene Ther 2013, 24:220-237.
-
(2013)
Hum Gene Ther
, vol.24
, pp. 220-237
-
-
Sundarasetty, B.S.1
Singh, V.K.2
Salguero, G.3
Geffers, R.4
Rickmann, M.5
Macke, L.6
-
4
-
-
33750571162
-
Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors
-
Lotem M., Zhao Y., Riley J., Hwu P., Morgan R.A., Rosenberg S.A., et al. Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors. JImmunother 2006, 29:616-627.
-
(2006)
JImmunother
, vol.29
, pp. 616-627
-
-
Lotem, M.1
Zhao, Y.2
Riley, J.3
Hwu, P.4
Morgan, R.A.5
Rosenberg, S.A.6
-
5
-
-
0037448352
-
Aserious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S., von Kalle C., Schmidt M., Le Deist F., Wulffraat N., McIntyre E., et al. Aserious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. NEngl J Med 2003, 348:255-256.
-
(2003)
NEngl J Med
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
Le Deist, F.4
Wulffraat, N.5
McIntyre, E.6
-
6
-
-
0033579358
-
Gene therapy death prompts review of adenovirus vector
-
Marshall E. Gene therapy death prompts review of adenovirus vector. Science 1999, 286:2244-2245.
-
(1999)
Science
, vol.286
, pp. 2244-2245
-
-
Marshall, E.1
-
7
-
-
78650476432
-
The proton sponge: a trick to enter cells the viruses did not exploit
-
Behr J.P. The proton sponge: a trick to enter cells the viruses did not exploit. Chimia 1997, 51:34-36.
-
(1997)
Chimia
, vol.51
, pp. 34-36
-
-
Behr, J.P.1
-
8
-
-
67649491055
-
Understanding biophysicochemical interactions at the nano-bio interface
-
Nel A.E., Madler L., Velegol D., Xia T., Hoek E.M., Somasundaran P., et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 2009, 8:543-557.
-
(2009)
Nat Mater
, vol.8
, pp. 543-557
-
-
Nel, A.E.1
Madler, L.2
Velegol, D.3
Xia, T.4
Hoek, E.M.5
Somasundaran, P.6
-
9
-
-
1942438703
-
GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery
-
Li W., Nicol F., Szoka F.C. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv Rev 2004, 56:967-985.
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 967-985
-
-
Li, W.1
Nicol, F.2
Szoka, F.C.3
-
10
-
-
0025042733
-
Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA
-
Parente R.A., Nir S., Szoka F.C. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry 1990, 29:8720-8728.
-
(1990)
Biochemistry
, vol.29
, pp. 8720-8728
-
-
Parente, R.A.1
Nir, S.2
Szoka, F.C.3
-
11
-
-
0037345795
-
Can nuclear localization signals enhance nuclear localization of plasmid DNA?
-
Nagasaki T., Myohoji T., Tachibana T., Futaki S., Tamagaki S. Can nuclear localization signals enhance nuclear localization of plasmid DNA?. Bioconjug Chem 2003, 14:282-286.
-
(2003)
Bioconjug Chem
, vol.14
, pp. 282-286
-
-
Nagasaki, T.1
Myohoji, T.2
Tachibana, T.3
Futaki, S.4
Tamagaki, S.5
-
12
-
-
33744906509
-
Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells
-
Nakamura T., Moriguchi R., Kogure K., Minoura A., Masuda T., Akita H., et al. Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells. Biol Pharm Bull 2006, 29:1290-1293.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 1290-1293
-
-
Nakamura, T.1
Moriguchi, R.2
Kogure, K.3
Minoura, A.4
Masuda, T.5
Akita, H.6
-
13
-
-
0344616895
-
Anovel transfecting peptide comprising a tetrameric nuclear localization sequence
-
Ritter W., Plank C., Lausier J., Rudolph C., Zink D., Reinhardt D., et al. Anovel transfecting peptide comprising a tetrameric nuclear localization sequence. JMol Med (Berl) 2003, 81:708-717.
-
(2003)
JMol Med (Berl)
, vol.81
, pp. 708-717
-
-
Ritter, W.1
Plank, C.2
Lausier, J.3
Rudolph, C.4
Zink, D.5
Reinhardt, D.6
-
14
-
-
0344494606
-
No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA
-
Tanimoto M., Kamiya H., Minakawa N., Matsuda A., Harashima H. No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA. Bioconjug Chem 2003, 14:1197-1202.
-
(2003)
Bioconjug Chem
, vol.14
, pp. 1197-1202
-
-
Tanimoto, M.1
Kamiya, H.2
Minakawa, N.3
Matsuda, A.4
Harashima, H.5
-
15
-
-
84867337397
-
HVJ-E/importin-beta hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery
-
Kawazu T., Kanzaki H., Uno A., Azuma H., Nagasaki T. HVJ-E/importin-beta hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery. Biomed Pharmacother 2012, 66:519-524.
-
(2012)
Biomed Pharmacother
, vol.66
, pp. 519-524
-
-
Kawazu, T.1
Kanzaki, H.2
Uno, A.3
Azuma, H.4
Nagasaki, T.5
-
16
-
-
59449093594
-
Oligosaccharide-mediated nuclear transport of nanoparticles
-
Niikura K., Sekiguchi S., Nishio T., Masuda T., Akita H., Matsuo Y., et al. Oligosaccharide-mediated nuclear transport of nanoparticles. Chembiochem 2008, 9:2623-2627.
-
(2008)
Chembiochem
, vol.9
, pp. 2623-2627
-
-
Niikura, K.1
Sekiguchi, S.2
Nishio, T.3
Masuda, T.4
Akita, H.5
Matsuo, Y.6
-
17
-
-
0038495795
-
Sugar-dependent nuclear import of glycosylated proteins in living cells
-
Rondanino C., Bousser M.T., Monsigny M., Roche A.C. Sugar-dependent nuclear import of glycosylated proteins in living cells. Glycobiology 2003, 13:509-519.
-
(2003)
Glycobiology
, vol.13
, pp. 509-519
-
-
Rondanino, C.1
Bousser, M.T.2
Monsigny, M.3
Roche, A.C.4
-
18
-
-
79961075704
-
Improving invivo hepatic transfection activity by controlling intracellular trafficking: the function of GALA and maltotriose
-
Akita H., Masuda T., Nishio T., Niikura K., Ijiro K., Harashima H. Improving invivo hepatic transfection activity by controlling intracellular trafficking: the function of GALA and maltotriose. Mol Pharm 2011, 8:1436-1442.
-
(2011)
Mol Pharm
, vol.8
, pp. 1436-1442
-
-
Akita, H.1
Masuda, T.2
Nishio, T.3
Niikura, K.4
Ijiro, K.5
Harashima, H.6
-
19
-
-
62149137705
-
Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process
-
Akita H., Kudo A., Minoura A., Yamaguti M., Khalil I.A., Moriguchi R., et al. Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process. Biomaterials 2009, 30:2940-2949.
-
(2009)
Biomaterials
, vol.30
, pp. 2940-2949
-
-
Akita, H.1
Kudo, A.2
Minoura, A.3
Yamaguti, M.4
Khalil, I.A.5
Moriguchi, R.6
-
20
-
-
79954599765
-
Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET
-
Shaheen S.M., Akita H., Yamashita A., Katoono R., Yui N., Biju V., et al. Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET. Nucleic Acids Res 2011, 39:e48.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Shaheen, S.M.1
Akita, H.2
Yamashita, A.3
Katoono, R.4
Yui, N.5
Biju, V.6
-
21
-
-
0030890748
-
Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
-
Wyman T.B., Nicol F., Zelphati O., Scaria P.V., Plank C., Szoka F.C. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry 1997, 36:3008-3017.
-
(1997)
Biochemistry
, vol.36
, pp. 3008-3017
-
-
Wyman, T.B.1
Nicol, F.2
Zelphati, O.3
Scaria, P.V.4
Plank, C.5
Szoka, F.C.6
-
22
-
-
79959900553
-
KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine
-
Shaheen S.M., Akita H., Nakamura T., Takayama S., Futaki S., Yamashita A., et al. KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine. Biomaterials 2011, 32:6342-6350.
-
(2011)
Biomaterials
, vol.32
, pp. 6342-6350
-
-
Shaheen, S.M.1
Akita, H.2
Nakamura, T.3
Takayama, S.4
Futaki, S.5
Yamashita, A.6
-
23
-
-
42549161844
-
The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver
-
McCaffrey A.P., Fawcett P., Nakai H., McCaffrey R.L., Ehrhardt A., Pham T.T., et al. The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver. Mol Ther 2008, 16:931-941.
-
(2008)
Mol Ther
, vol.16
, pp. 931-941
-
-
McCaffrey, A.P.1
Fawcett, P.2
Nakai, H.3
McCaffrey, R.L.4
Ehrhardt, A.5
Pham, T.T.6
-
24
-
-
24644504130
-
Toxicogenomics of cationic lipid-based vectors forgene therapy: impact of microarray technology
-
Omidi Y., Barar J., Akhtar S. Toxicogenomics of cationic lipid-based vectors forgene therapy: impact of microarray technology. Curr Drug Deliv 2005, 2:429-441.
-
(2005)
Curr Drug Deliv
, vol.2
, pp. 429-441
-
-
Omidi, Y.1
Barar, J.2
Akhtar, S.3
-
25
-
-
30644478022
-
Polypropylenimine dendrimer-induced gene expression changes: the effect of complexation with DNA, dendrimer generation and cell type
-
Omidi Y., Hollins A.J., Drayton R.M., Akhtar S. Polypropylenimine dendrimer-induced gene expression changes: the effect of complexation with DNA, dendrimer generation and cell type. JDrug Target 2005, 13:431-443.
-
(2005)
JDrug Target
, vol.13
, pp. 431-443
-
-
Omidi, Y.1
Hollins, A.J.2
Drayton, R.M.3
Akhtar, S.4
-
26
-
-
79961031809
-
ADNA microarray-based analysis of the host response to a nonviral gene carrier: a strategy for improving the immune response
-
Hatakeyama H., Ito E., Yamamoto M., Akita H., Hayashi Y., Kajimoto K., et al. ADNA microarray-based analysis of the host response to a nonviral gene carrier: a strategy for improving the immune response. Mol Ther 2011, 19:1487-1498.
-
(2011)
Mol Ther
, vol.19
, pp. 1487-1498
-
-
Hatakeyama, H.1
Ito, E.2
Yamamoto, M.3
Akita, H.4
Hayashi, Y.5
Kajimoto, K.6
-
27
-
-
1842846611
-
Inhibition of cytokine-induced JAK-STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid
-
Chen C.W., Chao Y., Chang Y.H., Hsu M.J., Lin W.W. Inhibition of cytokine-induced JAK-STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid. Br J Pharmacol 2002, 137:1011-1020.
-
(2002)
Br J Pharmacol
, vol.137
, pp. 1011-1020
-
-
Chen, C.W.1
Chao, Y.2
Chang, Y.H.3
Hsu, M.J.4
Lin, W.W.5
-
28
-
-
53749106185
-
NF-kappaB signaling differentially regulates influenza virus RNA synthesis
-
Kumar N., Xin Z.T., Liang Y., Ly H., Liang Y. NF-kappaB signaling differentially regulates influenza virus RNA synthesis. JVirol 2008, 82:9880-9889.
-
(2008)
JVirol
, vol.82
, pp. 9880-9889
-
-
Kumar, N.1
Xin, Z.T.2
Liang, Y.3
Ly, H.4
Liang, Y.5
-
29
-
-
0035210533
-
Stearylated arginine-rich peptides: a new class of transfection systems
-
Futaki S., Ohashi W., Suzuki T., Niwa M., Tanaka S., Ueda K., et al. Stearylated arginine-rich peptides: a new class of transfection systems. Bioconjug Chem 2001, 12:1005-1011.
-
(2001)
Bioconjug Chem
, vol.12
, pp. 1005-1011
-
-
Futaki, S.1
Ohashi, W.2
Suzuki, T.3
Niwa, M.4
Tanaka, S.5
Ueda, K.6
-
30
-
-
2442421428
-
Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system
-
Kakudo T., Chaki S., Futaki S., Nakase I., Akaji K., Kawakami T., et al. Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system. Biochemistry 2004, 43:5618-5628.
-
(2004)
Biochemistry
, vol.43
, pp. 5618-5628
-
-
Kakudo, T.1
Chaki, S.2
Futaki, S.3
Nakase, I.4
Akaji, K.5
Kawakami, T.6
-
31
-
-
9144255378
-
Adjuvant-mediated tumor regression and tumor-specific cytotoxic response are impaired in MyD88-deficient mice
-
Akazawa T., Masuda H., Saeki Y., Matsumoto M., Takeda K., Tsujimura K., et al. Adjuvant-mediated tumor regression and tumor-specific cytotoxic response are impaired in MyD88-deficient mice. Cancer Res 2004, 64:757-764.
-
(2004)
Cancer Res
, vol.64
, pp. 757-764
-
-
Akazawa, T.1
Masuda, H.2
Saeki, Y.3
Matsumoto, M.4
Takeda, K.5
Tsujimura, K.6
-
32
-
-
78650871053
-
Small molecule inhibitors of NF-kB and JAK/STAT signal transduction pathways as promising anti-inflammatory therapeutics
-
Ivanenkov Y.A., Balakin K.V., Lavrovsky Y. Small molecule inhibitors of NF-kB and JAK/STAT signal transduction pathways as promising anti-inflammatory therapeutics. Mini Rev Med Chem 2011, 11:55-78.
-
(2011)
Mini Rev Med Chem
, vol.11
, pp. 55-78
-
-
Ivanenkov, Y.A.1
Balakin, K.V.2
Lavrovsky, Y.3
-
33
-
-
84855832580
-
Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins
-
Knosp C.A., Johnston J.A. Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins. Immunology 2012, 135:101-111.
-
(2012)
Immunology
, vol.135
, pp. 101-111
-
-
Knosp, C.A.1
Johnston, J.A.2
-
34
-
-
0030755934
-
Structure and function of a new STAT-induced STAT inhibitor
-
Naka T., Narazaki M., Hirata M., Matsumoto T., Minamoto S., Aono A., et al. Structure and function of a new STAT-induced STAT inhibitor. Nature 1997, 387:924-929.
-
(1997)
Nature
, vol.387
, pp. 924-929
-
-
Naka, T.1
Narazaki, M.2
Hirata, M.3
Matsumoto, T.4
Minamoto, S.5
Aono, A.6
-
35
-
-
79955509835
-
Direct effects of type I interferons on cells of the immune system
-
Hervas-Stubbs S., Perez-Gracia J.L., Rouzaut A., Sanmamed M.F., Le Bon A., Melero I. Direct effects of type I interferons on cells of the immune system. Clin Cancer Res 2011, 17:2619-2627.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2619-2627
-
-
Hervas-Stubbs, S.1
Perez-Gracia, J.L.2
Rouzaut, A.3
Sanmamed, M.F.4
Le Bon, A.5
Melero, I.6
-
36
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434:772-777.
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
Mizutani, T.6
-
37
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
-
Sato M., Suemori H., Hata N., Asagiri M., Ogasawara K., Nakao K., et al. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 2000, 13:539-548.
-
(2000)
Immunity
, vol.13
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
Asagiri, M.4
Ogasawara, K.5
Nakao, K.6
-
38
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010, 11:373-384.
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
39
-
-
84865298775
-
Dissecting negative regulation of Toll-like receptor signaling
-
Kondo T., Kawai T., Akira S. Dissecting negative regulation of Toll-like receptor signaling. Trends Immunol 2012, 33:449-458.
-
(2012)
Trends Immunol
, vol.33
, pp. 449-458
-
-
Kondo, T.1
Kawai, T.2
Akira, S.3
-
40
-
-
80052164116
-
Cytoplasmic DNA innate immune pathways
-
Barber G.N. Cytoplasmic DNA innate immune pathways. Immunol Rev 2011, 243:99-108.
-
(2011)
Immunol Rev
, vol.243
, pp. 99-108
-
-
Barber, G.N.1
-
41
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu Y.H., Macmillan J.B., Chen Z.J. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 2009, 138:576-591.
-
(2009)
Cell
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
Macmillan, J.B.2
Chen, Z.J.3
-
42
-
-
58049217490
-
RNA recognition and signal transduction by RIG-I-like receptors
-
Yoneyama M., Fujita T. RNA recognition and signal transduction by RIG-I-like receptors. Immunol Rev 2009, 227:54-65.
-
(2009)
Immunol Rev
, vol.227
, pp. 54-65
-
-
Yoneyama, M.1
Fujita, T.2
-
43
-
-
0038393016
-
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald K.A., McWhirter S.M., Faia K.L., Rowe D.C., Latz E., Golenbock D.T., et al. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 2003, 4:491-496.
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
-
44
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma S., tenOever B.R., Grandvaux N., Zhou G.P., Lin R., Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science 2003, 300:1148-1151.
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
tenOever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.5
Hiscott, J.6
-
45
-
-
84871218439
-
STING and the innate immune response to nucleic acids in the cytosol
-
Burdette D.L., Vance R.E. STING and the innate immune response to nucleic acids in the cytosol. Nat Immunol 2013, 14:19-26.
-
(2013)
Nat Immunol
, vol.14
, pp. 19-26
-
-
Burdette, D.L.1
Vance, R.E.2
-
46
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A., Wang Z., Choi M.K., Yanai H., Negishi H., Ban T., et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007, 448:501-505.
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
-
47
-
-
84874278336
-
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
-
Kondo T., Kobayashi J., Saitoh T., Maruyama K., Ishii K.J., Barber G.N., et al. DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking. Proc Natl Acad Sci U S A 2013, 110:2969-2974.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 2969-2974
-
-
Kondo, T.1
Kobayashi, J.2
Saitoh, T.3
Maruyama, K.4
Ishii, K.J.5
Barber, G.N.6
-
48
-
-
84859986329
-
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor
-
Jin T., Perry A., Jiang J., Smith P., Curry J.A., Unterholzner L., et al. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity 2012, 36:561-571.
-
(2012)
Immunity
, vol.36
, pp. 561-571
-
-
Jin, T.1
Perry, A.2
Jiang, J.3
Smith, P.4
Curry, J.A.5
Unterholzner, L.6
-
49
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner L., Keating S.E., Baran M., Horan K.A., Jensen S.B., Sharma S., et al. IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol 2010, 11:997-1004.
-
(2010)
Nat Immunol
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
Sharma, S.6
-
50
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve D.A., Petrilli V., Zaiss A.K., White L.R., Clark S.A., Ross P.J., et al. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 2008, 452:103-107.
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
-
51
-
-
74049160009
-
Mechanisms maintaining peripheral tolerance
-
Mueller D.L. Mechanisms maintaining peripheral tolerance. Nat Immunol 2010, 11:21-27.
-
(2010)
Nat Immunol
, vol.11
, pp. 21-27
-
-
Mueller, D.L.1
-
52
-
-
3042699400
-
Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A
-
Genin P., Morin P., Civas A. Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A. JVirol 2003, 77:7113-7119.
-
(2003)
JVirol
, vol.77
, pp. 7113-7119
-
-
Genin, P.1
Morin, P.2
Civas, A.3
-
53
-
-
0034644718
-
Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon and silencing by hypermethylation
-
Lu R., Au W.C., Yeow W.S., Hageman N., Pitha P.M. Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon and silencing by hypermethylation. JBiol Chem 2000, 275:31805-31812.
-
(2000)
JBiol Chem
, vol.275
, pp. 31805-31812
-
-
Lu, R.1
Au, W.C.2
Yeow, W.S.3
Hageman, N.4
Pitha, P.M.5
-
54
-
-
38949093002
-
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
-
Ishii K.J., Kawagoe T., Koyama S., Matsui K., Kumar H., Kawai T., et al. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 2008, 451:725-729.
-
(2008)
Nature
, vol.451
, pp. 725-729
-
-
Ishii, K.J.1
Kawagoe, T.2
Koyama, S.3
Matsui, K.4
Kumar, H.5
Kawai, T.6
-
55
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008, 455:674-678.
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
56
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa H., Ma Z., Barber G.N. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 2009, 461:788-792.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
57
-
-
66649109939
-
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
-
Sun W., Li Y., Chen L., Chen H., You F., Zhou X., et al. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci U S A 2009, 106:8653-8658.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8653-8658
-
-
Sun, W.1
Li, Y.2
Chen, L.3
Chen, H.4
You, F.5
Zhou, X.6
-
58
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong B., Yang Y., Li S., Wang Y.Y., Li Y., Diao F., et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 2008, 29:538-550.
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
Yang, Y.2
Li, S.3
Wang, Y.Y.4
Li, Y.5
Diao, F.6
-
59
-
-
80054966913
-
STING is a direct innate immune sensor of cyclic di-GMP
-
Burdette D.L., Monroe K.M., Sotelo-Troha K., Iwig J.S., Eckert B., Hyodo M., et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature 2011, 478:515-518.
-
(2011)
Nature
, vol.478
, pp. 515-518
-
-
Burdette, D.L.1
Monroe, K.M.2
Sotelo-Troha, K.3
Iwig, J.S.4
Eckert, B.5
Hyodo, M.6
-
60
-
-
84864144593
-
Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING
-
Holm C.K., Jensen S.B., Jakobsen M.R., Cheshenko N., Horan K.A., Moeller H.B., et al. Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING. Nat Immunol 2012, 13:737-743.
-
(2012)
Nat Immunol
, vol.13
, pp. 737-743
-
-
Holm, C.K.1
Jensen, S.B.2
Jakobsen, M.R.3
Cheshenko, N.4
Horan, K.A.5
Moeller, H.B.6
-
61
-
-
79954631519
-
RNA species generated in vaccinia virus infected cells activate cell type-specific MDA5 or RIG-I dependent interferon gene transcription and PKR dependent apoptosis
-
Myskiw C., Arsenio J., Booy E.P., Hammett C., Deschambault Y., Gibson S.B., et al. RNA species generated in vaccinia virus infected cells activate cell type-specific MDA5 or RIG-I dependent interferon gene transcription and PKR dependent apoptosis. Virology 2011, 413:183-193.
-
(2011)
Virology
, vol.413
, pp. 183-193
-
-
Myskiw, C.1
Arsenio, J.2
Booy, E.P.3
Hammett, C.4
Deschambault, Y.5
Gibson, S.B.6
-
62
-
-
78049275345
-
Induction of type I interferon by adenovirus-encoded small RNAs
-
Yamaguchi T., Kawabata K., Kouyama E., Ishii K.J., Katayama K., Suzuki T., et al. Induction of type I interferon by adenovirus-encoded small RNAs. Proc Natl Acad Sci U S A 2010, 107:17286-17291.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 17286-17291
-
-
Yamaguchi, T.1
Kawabata, K.2
Kouyama, E.3
Ishii, K.J.4
Katayama, K.5
Suzuki, T.6
-
63
-
-
77950883727
-
Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA
-
Martinez J., Huang X., Yang Y. Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA. Proc Natl Acad Sci U S A 2010, 107:6442-6447.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 6442-6447
-
-
Martinez, J.1
Huang, X.2
Yang, Y.3
|