A lesson learned from the H3.3K27M mutation found in pediatric glioma A new approach to the study of the function of histone modifications in vivo?

Cell Cycle

Volumn 12, Issue 16, 2013, Pages 2546-2552

  Chan, Kui Ming ^a   Han, Jing ^a   Fang, Dong ^a   Gan, Haiyun ^a   Zhang, Zhiguo ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

Cancer epigenetics; Diffuse intrinsic pontine glioma (DIPGs); EZH2; Glioblastoma (GBM); H3K27me3; H3K79me2; H4K20me3; Histone modification; PRC2 complex; SET domain; Tumorigenesis

Indexed keywords

HISTONE H3; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; METHIONINE;

ARTICLE; CARCINOGENESIS; CHILDHOOD DISEASE; CHROMATIN; ENZYME ACTIVE SITE; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GLIOBLASTOMA; HISTONE METHYLATION; HUMAN; IN VIVO STUDY;

MAMMALIA;

CANCER EPIGENETICS; DIFFUSE INTRINSIC PONTINE GLIOMA (DIPGS); EZH2; GLIOBLASTOMA (GBM); H3K27ME3; H3K79ME2; H4K20ME3; HISTONE MODIFICATION; PRC2 COMPLEX; SET-DOMAIN; TUMORIGENESIS;

AMINO ACID SEQUENCE; CHILD; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE;

EID: 84883226328     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.25625     Document Type: Article

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