Berberine metabolites exhibit triglyceride-lowering effects via activation of AMP-activated protein kinase in Hep G2 cells

Journal of Ethnopharmacology

Volumn 149, Issue 2, 2013, Pages 576-582

  Cao, Shijie ^a   Zhou, Yan ^a   Xu, Peixiang ^a   Wang, Ying ^a   Yan, Jiankun ^a   Bin, Wen ^a   Qiu, Feng ^a   Kang, Ning ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

AMPK; Berberine; Hyperlipidemia; Metabolites; Triglyceride

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ANTILIPEMIC AGENT; BERBERINE; BERBERINE DERIVATIVE; BEROLINE; COLUMBAMINE; DEMETHYLENEBERBERINE; FATTY ACID SYNTHASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; JATRORRHIZINE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANTIHYPERLIPIDEMIC ACTIVITY; ARTICLE; CELL LEVEL; CELL STRAIN HEPG2; CHINESE HERB; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG METABOLISM; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPERLIPIDEMIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

RATTUS;

AMPK; BERBERINE; HYPERLIPIDEMIA; METABOLITES; TRIGLYCERIDE;

AMP-ACTIVATED PROTEIN KINASES; BERBERINE ALKALOIDS; CELL SURVIVAL; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; HYPOLIPIDEMIC AGENTS; LIPID METABOLISM; TRIGLYCERIDES;

EID: 84883165966     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.07.025     Document Type: Article

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