Multiple modes of α7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents

Molecular Pharmacology

Volumn 84, Issue 3, 2013, Pages 459-475

  Peng, Can ^a   Kimbrell, Matthew R ^a   Tian, Chengju ^a   Pack, Thomas F ^a   Crooks, Peter A ^b   Fifer, E Kim ^b   Papke, Roger L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4,5 TETRA [5 [1(3 BENZYL)PYRIDINIUM]PENT 1 YL]TETRABROMIDE; 2,2,6,6 TETRAMETHYLPIPERIDIN 4 YL HEPTANOATE; BIS (2,2,6,6 TETRAMETHYL 4 PIPERIDINYL)SEBACATE; BUNGAROTOXIN RECEPTOR; CALCIUM ION; CHOLINE; ION CHANNEL; LIDOCAINE ETHOBROMIDE; MECAMYLAMINE; PNU 120596; PROTEIN INHIBITOR; TETRACAINE; UNCLASSIFIED DRUG; 1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-METHYLISOXAZOL-3-YL)UREA; CALCIUM; CARBANILAMIDE DERIVATIVE; CYTOTOXIN; ISOXAZOLE DERIVATIVE; NICOTINIC AGENT; NICOTINIC RECEPTOR BLOCKING AGENT;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ION CURRENT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS LAEVIS; ANIMAL; CELL LINE; DRUG EFFECTS; FEMALE; HUMAN; METABOLISM; NERVE CELL; PATCH CLAMP TECHNIQUE; PHYSIOLOGY;

ALLOSTERIC REGULATION; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; CALCIUM; CELL LINE; CHOLINE; CYTOTOXINS; FEMALE; HUMANS; ISOXAZOLES; NEURONS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; PHENYLUREA COMPOUNDS; XENOPUS LAEVIS;

EID: 84883164868     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.086462     Document Type: Article

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