Selective inhibition of acetylcholine-evoked responses of α7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists

Molecular Pharmacology

Volumn 76, Issue 3, 2009, Pages 652-666

  López Hernández, Gretchen Y ^a   Thinschmidt, Jeffrey S ^a   Zheng, Guangrong ^b   Zhang, Zhenfa ^b   Crooks, Peter A ^b   Dwoskin, Linda P ^b   Papke, Roger L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4,5 TETRA [5 [1 (3 BENZYL)PYRIDINIUM]PENT 1 YL]BENZENE TETRABROMIDE; 1,3,5 TRI [5 (1 QUINOLINUM) PENT 1 YN 1 YL] BENZENE TRIBROMIDE; 1,3,5, TRI [5 [1 (2 PICOPICOLINIUM)]PENT 1 YN 1 YL]BENZENE TRIBROMIDE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ACETYLCHOLINE; BENZENE DERIVATIVE; BROMINE DERIVATIVE; METHYLLYCACONITINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; EVOKED RESPONSE; HIPPOCAMPUS; INTERNEURON; MALE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS LAEVIS;

ACETYLCHOLINE; ANIMALS; NEURONS; OOCYTES; QUATERNARY AMMONIUM COMPOUNDS; RATS; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 69549124713     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.056176     Document Type: Article

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