Investigation of the molecular mechanism of the α7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states

Molecular Pharmacology

Volumn 80, Issue 6, 2011, Pages 1013-1032

  Williams, Dustin K ^a   Wang, Jingyi ^b   Papke, Roger L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; ION CHANNEL; N (5 CHLORO 2,4 DIMETHOXYPHENYL) N' (5 METHYL 3 ISOXAZOLYL)UREA; PNU 120596; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; DESENSITIZATION; DRUG RECEPTOR BINDING; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS LAEVIS;

ALLOSTERIC REGULATION; ANIMALS; CELLS, CULTURED; FEMALE; HUMANS; ISOXAZOLES; NICOTINIC AGONISTS; PHENYLUREA COMPOUNDS; PROTEIN STABILITY; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 81555222819     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.074302     Document Type: Article

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