Growth, metabolic activity, and productivity of immobilized and freely suspended CHO cells in perfusion culture

Biotechnology and Applied Biochemistry

Volumn 60, Issue 4, 2013, Pages 436-445

  Hilal Alnaqbi, Ali ^a,b   Hu, Alan Y C ^c   Zhang, Zhibing ^c   Al Rubeai, Mohamed ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

3D culture; cell cycle; CHO cells; microcarriers; oxygen uptake rate; perfusion culture

Indexed keywords

3-D CULTURES; CELL CYCLE; CHO CELL; MICROCARRIERS; OXYGEN UPTAKE RATES; PERFUSION CULTURES;

BATCH CELL CULTURE; BIOREACTORS; CARRIER CONCENTRATION; CYTOLOGY; METABOLISM; OXYGEN; PRODUCTIVITY; SCANNING ELECTRON MICROSCOPY; SILICONES;

CELLS;

SILICONE;

ANIMAL CELL; ARTICLE; BIOREACTOR; CELL ACTIVITY; CELL ANCHORAGE; CELL CULTURE; CELL CYCLE S PHASE; CELL GROWTH; CELL METABOLISM; CELL STRUCTURE; CELL VIABILITY; CHO CELL; FEMALE; GROWTH RATE; IMMOBILIZED CELL; MICROCARRIER CULTURE; MICROVILLUS; NONHUMAN; OXYGEN CONSUMPTION; PERFUSION; PRODUCTIVITY;

CRICETULUS GRISEUS;

3D CULTURE; CELL CYCLE; CHO CELLS; MICROCARRIERS; OXYGEN UPTAKE RATE; PERFUSION CULTURE;

ANIMALS; BETA-GALACTOSIDASE; BIOLOGICAL TRANSPORT; BIOREACTORS; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL PROLIFERATION; CELLS, IMMOBILIZED; CHO CELLS; CRICETINAE; CRICETULUS; KINETICS; OXYGEN; PERFUSION; POROSITY; RECOMBINANT PROTEINS; SUSPENSIONS;

EID: 84883164684     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1103     Document Type: Article

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