Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Guellouz, Asma ^a,b   Valerio Lepiniec, Marie ^a,b   Urvoas, Agathe ^a,b   Chevrel, Anne ^a,b   Graille, Marc ^a,b,c   Fourati Kammoun, Zaineb ^a,b,c   Desmadril, Michel ^a,b   van Tilbeurgh, Herman ^a,b   Minard, Philippe ^a,b  

^a INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

^b CNRS   (France)

^c LABORATOIRE DE BIOCHIMIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL HELICOIDAL REPEAT PROTEIN; BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE LIBRARY; MOLECULAR CLONING; PHAGE DISPLAY; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN POLYMERIZATION; PROTEIN TARGETING; SEQUENCE HOMOLOGY; THERMOSTABILITY; VARIABLE NUMBER OF TANDEM REPEAT;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GREEN FLUORESCENT PROTEINS; IMMOBILIZED PROTEINS; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84883158675     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071512     Document Type: Article

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