Structures of in Vitro Evolved Binding Sites on Neocarzinostatin Scaffold Reveal Unanticipated Evolutionary Pathways

Journal of Molecular Biology

Volumn 358, Issue 2, 2006, Pages 455-471

  Drevelle, Antoine ^a   Graille, Marc ^a   Heyd, Bernadette ^a   Sorel, Isabelle ^a   Ulryck, Nathalie ^a   Pecorari, Frédéric ^a   Desmadril, Michel ^a   van Tilbeurgh, Herman ^a   Minard, Philippe ^a  

^a INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

Author keywords

binding site; directed evolution; Neocarzinostatin; phage display; structure

Indexed keywords

DIMER; ZINOSTATIN;

ARTICLE; BINDING SITE; CONFORMATION; IN VITRO STUDY; LIGAND BINDING; MOLECULE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; WILD TYPE; X RAY;

EID: 33646519459     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.02.002     Document Type: Article

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