Design, Production and Molecular Structure of a New Family of Artificial Alpha-helicoidal Repeat Proteins (αRep) Based on Thermostable HEAT-like Repeats

Journal of Molecular Biology

Volumn 404, Issue 2, 2010, Pages 307-327

  Urvoas, Agathe ^a,b   Guellouz, Asma ^a,b   Valerio Lepiniec, Marie ^a,b   Graille, Marc ^a,b   Durand, Dominique ^a,b   Desravines, Danielle C ^a,b,c   van Tilbeurgh, Herman ^a,b   Desmadril, Michel ^a,b   Minard, Philippe ^a,b  

^a INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

^b CNRS   (France)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

Combinatorial library; HEAT repeat protein; Protein design; Protein scaffold

Indexed keywords

ALPHA HELICOIDAL REPEAT PROTEIN; DIMER; TETRATRICOPEPTIDE REPEAT PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL STRUCTURE; CRYSTALLIZATION; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN SYNTHESIS; RADIATION SCATTERING; SEQUENCE ANALYSIS; THERMOSTABILITY;

EID: 78349304669     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.09.048     Document Type: Article

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