Bone Marrow Stem Cells. Properties and Pluripotency

Principles of Regenerative Medicine

Volumn , Issue , 2008, Pages 268-283

  Xaymardan, Munira ^a   Cimini, Massimo ^a   Weisel, Richard D ^a   Li, Ren Ke ^b  

^a Toronto Medical Discover Tower   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882916675     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012369410-2.50018-8     Document Type: Chapter

References (84)

1. Abbott J.D., Huang Y., Liu D., Hickey R., Krause D.S., Giordano F.J. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce hom. Circulation 2004, 110(21):3300-3305.
2. Abe S., Lauby G., Boyer C., Rennard S.I., Sharp J.G. Transplanted BM and BM side population cells contribute progeny to the lung and liver in irradiated mice. Cytotherapy 2003, 5(6):523-533.
3. Achen M.G., Stacker S.A. The vascular endothelial growth factor family; proteins which guide the development of the vasculature. Int. J. Exp. Pathol. 1998, 79(5):255-265.
4. Asahara T., Masuda H., Takahashi T., Kalka C., Pastore C., Silver M., Kearne M., Magner M., Isner J.M. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ. Res. 1999, 85(3):221-228.
5. Barria E., Mikels A., Haas M. Maintenance and self-renewal of long-term reconstituting hematopoietic stem cells supported by amniotic fluid. Stem Cells Dev. 2004, 13(5):548-562.
6. Behfar A., Zingman L.V., Hodgson D.M., Rauzier J.M., Kane G.C., Terzic A., Puceat M. Stem cell differentiation requires a paracrine pathway in the heart. Faseb J. 2002, 16(12):1558-1566.
7. Beltrami A.P., Urbanek K., Kajstura J., Yan S.M., Finato N., Bussani R., Nadal-Ginard B., Silvestri F., Leri A., Beltrami C.A. Evidence that human cardiac myocytes divide after myocardial infarction. N. Engl. J. Med. 2001, 344(23):1750-1757.
8. Beltrami A.P., Barlucchi L., Torella D., Baker M., Limana F., Chimenti S., Kasahara H., Rota M., Musso E., Urbanek K. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003, 114(6):763-776.
9. Bittira B., Kuang J.Q., Al-Khaldi A., Shum-Tim D., Chiu R.C. In vitro preprogramming of marrow stromal cells for myocardial regeneration. Ann. Thorac. Surg. 2002, 74(4):1154-1159. discussion 1159-1160.
10. Bossolasco P., Corti S., Strazzer S., Borsotti C., Del Bo R., Fortunato F., Salani S., Quirici N., Bertolini F., Gobbi A. Skeletal muscle differentiation potential of human adult bone marrow cells. Exp. Cell Res. 2004, 295(1):66-78.
11. Bradfute S.B., Graubert T.A., Goodell M.A. Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp. Hematol. 2005, 33(7):836-843.
12. Brazelton T.R., Rossi F.M., Keshet G.I., Blau H.M. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 2000, 290(5497):1775-1779.
13. Britten M.B., Abolmaali N.D., Assmus B., Lehmann R., Honold J., Schmitt J., Vogl T.J., Martin H., Schachinger V., Dimmeler S. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial. Circulation 2003, 108(18):2212-2218.
14. Carmeliet P., Ferreira V., Breier G., Pollefeyt S., Kieckens L., Gertsenstein M., Fahrig M., Vandenhoeck A., Harpal K., Eberhardt C. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996, 380(6573):435-439.
15. Ceradini D.J., Gurtner G.C. Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue. Trends Cardiovasc.Med. 2005, 15(2):57-63.
16. Chandrashekhar Y. Role of apoptosis in ventricular remodeling. Curr. Heart Fail. Rep. 2005, 2(1):18-22.
17. Chute J.P., Muramoto G.G., Dressman H.K., Wolfe G., Chao N.J., Lin S. Molecular profile and partial functional analysis of novel endothelial cell derived growth factors that regulate hematopoiesis. Stem Cells 2006, 24(5):1315-1327.
18. Cleland J.G., Freemantle N., Coletta A.P., Clark A.L. Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE. Eur. J. Heart Fail. 2006, 8(1):105-110.
19. de Boer J., Siddappa R., Gaspar C., van Apeldoorn A., Fodde R., van Blitterswijk C. Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells. Bone 2004, 34(5):818-826.
20. Deb A., Wang S., Skelding K.A., Miller D., Simper D., Caplice N.M. Bone marrow-derived cardiomyocytes are present in adult human heart: a study of gender-mismatched bone marrow transplantation patients. Circulation 2003, 107(9):1247-1249.
21. Driessen R.L., Johnston H.M., Nilsson S.K. Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region. Exp. Hematol. 2003, 31(12):1284-1291.
22. Fibbe W.E., Pruijt J.F., van Kooyk Y., Figdor C.G., Opdenakker G., Willemze R. The role of metalloproteinases and adhesion molecules in interleukin-8-induced stem-cell mobilization. Semin. Hematol. 2000, 37:19-24. (1 Suppl 2).
23. Frangogiannis N.G., Lindsey M.L., Michael L.H., Youker K.A., Bressler R.B., Mendoza L.H., Spengler R.N., Smith C.W., Entman M.L. Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusio. Circulation 1998, 98(7):699-710.
24. Friedenstein A.J., Ivanov-Smolenski A.A., Chajlakjan R.K., Gorskaya U.F., Kuralesova A.I., Latzinik N.W., Gerasimow U.W. Origin of bone marrow stromal mechanocytes in radiochimeras and heterotopic transplants. Exp. Hematol. 1978, 6(5):440-444.
25. Fujii H., Hirose T., Oe S., Yasuchika K., Azuma H., Fujikawa T., Nagao M., Yamaoka Y. Contribution of bone marrow cells to liver regeneration after partial hepatectomy in mice. J. Hepatol. 2002, 36(5):653-659.
26. Fukuda K. Generation of cardiomyocytes from mesenchymal stem cells. Tanpakushitsu Kakusan Koso 2000, 45(13 Suppl):2078-2084.
27. Gehling U.M., Ergun S., Schumacher U., Wagener C., Pantel K., Otte M., Schuch G., Schafhausen P., Mende T., Kilic N. In vitroof endothelial cells from AC133-positive progenitor cells. Blood 2000, 95(10):3106-3112.
28. Gengozian N., Makinodan T. Antibody response of lethally x-irradiated mice treated with rat bone marrow. J. Immunol. 1956, 77(6):430-436.
29. Goodell M.A., Brose K., Paradis G., Conner A.S., Mulligan R.C. Isolation and functional properties of murine hematopoietic stem cells that are replicating. in vivo. J. Exp.Med. 1996, 183(4):1797-1806.
30. Gregory C.A., Prockop D.J., Spees J.L. Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation. Exp. Cell Res. 2005, 306(2):330-335.
31. Gronthos S., Graves S.E., Ohta S., Simmons P.J. The STRO-1 fraction of adult human bone marrow contains the osteogenic precursors. Blood 1994, 84(12):4164-4173.
32. Grunewald M., Avraham I., Dor Y., Bachar-Lustig E., Itin A., Yung S., Chimenti S., Landsman L., Abramovitch R., Keshet E. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell 2006, 124(1):175-189.
33. Hiasa K., Egashira K., Kitamoto S., Ishibashi M., Inoue S., Ni W., Zhao Q., Nagata S., Katoh M., Sata M. Bone marrow mononuclear cell therapy limits myocardial infarct size through vascular endothelial growth factor. Basic Res. Cardiol. 2004, 99(3):165-172.
34. Jiang Y., Jahagirdar B.N., Reinhardt R.L., Schwartz R.E., Keene C.D., Ortiz-Gonzalez X.R., Reyes M., Lenvik T., Lund T., Blackstad M. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002, 418(6893):41-49.
35. Kajstura J., Leri A., Finato N., Di Loreto C., Beltrami C.A., Anversa P. Myocyte proliferation in end-stage cardiac failure in humans. Proc. Natl Acad. Sci. USA 1998, 95(15):8801-8805.
36. Kamihata H., Matsubara H., Nishiue T., Fujiyama S., Tsutsumi Y., Ozono R., Masaki H., Mori Y., Iba O., Tateishi E. Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, ang. Circulation 2001, 104(9):1046-1052.
37. Kang H.J., Kim H.S., Zhang S.Y., Park K.W., Cho H.J., Koo B.K., Kim Y.J., Soo Lee D., Sohn D.W., Han K.S. Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function an. Lancet 2004, 363(9411):751-756.
38. Kawada H., Fujita J., Kinjo K., Matsuzaki Y., Tsuma M., Miyatake H., Muguruma Y., Tsuboi K., Itabashi Y., Ikeda Y. Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood 2004, 104(12):3581-3587.
39. Kocher A.A., Schuster M.D., Szabolcs M.J., Takuma S., Burkhoff D., Wang J., Homma S., Edwards N.M., Itescu S. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac f. Nat.Med. 2001, 7(4):430-436.
40. Kucia M., Dawn B., Hunt G., Guo Y., Wysoczynski M., Majka M., Ratajczak J., Rezzoug F., Ildstad S.T., Bolli R. Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction. Circ. Res. 2004, 95(12):1191-1199.
41. Kuethe F., Figulla H.R., Herzau M., Voth M., Fritzenwanger M., Opfermann T., Pachmann K., Krack A., Sayer H.G., Gottschild D. Treatment with granulocyte colony-stimulating factor for mobilization of bone marrow cells in patients with acute myocardial infarction. Am. Heart J. 2005, 150(1):115.
42. Kukielka G.L., Smith C.W., LaRosa G.J., Manning A.M., Mendoza L.H., Daly T.J., Hughes B.J., Youker K.A., Hawkins H.K., Michael L.H. Interleukin-8 gene induction in the myocardium after ischemia and reperfusion. in vivo. J. Clin. Invest. 1995, 95(1):89-103.
43. Lagostena L., Avitabile D., De Falco E., Orlandi A., Grassi F., Iachininoto M.G., Ragone G., Fucile S., Pompilio G., Eusebi F. Electrophysiological properties of mouse bone marrow c-kit + cells co-cultured onto neonatal cardiac myocytes. Cardiovasc. Res. 2005, 66(3):482-492.
44. Laguens R., Cabeza Meckert P., Vera Janavel G., Del Valle H., Lascano E., Negroni J., Werba P., Cuniberti L., Martinez V., Melo C. Entrance in mitosis of adult cardiomyocytes in ischemic pig hearts after plasmid-mediated rhVEGF165 gene transfer. Gene Ther. 2002, 9(24):1676-1681.
45. Leone A.M., Rutella S., Bonanno G., Contemi A.M., de Ritis D.G., Giannico M.B., Rebuzzi A.G., Leone G., Crea F. Endogenous G-CSF and CD34() cell mobilization after acute myocardial infarction. Int. J. Cardiol. 2005, 111(2):202-208.
46. Leone A.M., Rutella S., Bonanno G., Abbate A., Rebuzzi A.G., Giovannini S., Lombardi M., Galiuto L., Liuzzo G., Andreotti F. Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function. Eur. Heart J. 2005, 26(12):1196-1204.
47. Levesque J.P., Takamatsu Y., Nilsson S.K., Haylock D.N., Simmons P.J. Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granul. Blood 2001, 98(5):1289-1297.
48. Li T.S., Hayashi M., Ito H., Furutani A., Murata T., Matsuzaki M., Hamano K. Regeneration of infarcted myocardium by intramyocardial implantation of ex vivo transforming growth factor-beta-preprogrammed bone marrow stem cells. Circulation 2005, 111(19):2438-2445.
49. Liadaki K., Kho A.T., Sanoudou D., Schienda J., Flint A., Beggs A.H., Kohane I.S., Kunkel L.M. Side population cells isolated from different tissues share transcriptome signatures and express tissue-specific markers. Exp. Cell Res. 2005, 303(2):360-374.
50. Lunde K., Solheim S., Aakhus S., Arnesen H., Abdelnoor M., Forfang K. Autologous stem cell transplantation in acute myocardial infarction: The ASTAMI randomized controlled trial. Intracoronary transplantation of autologous monon. Scand Cardiovasc. J. 2005, 39(3):150-158.
51. Murry C.E., Soonpaa M.H., Reinecke H., Nakajima H., Nakajima O.H., Rubart M., Pasumarthi K.B., Virag J.I., Bartelmez S.H., Pappa V. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarctions. Nature 2004, 428:664-668.
52. Menasche P. Cell transplantation in myocardium. Ann. Thorac. Surg. 2003, 75(6 Suppl):S20-S28.
53. Minatoguchi S., Takemura G., Chen X.H., Wang N., Uno Y., Koda M., Arai M., Misao Y., Lu C., Suzuki K. Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfar. Circulation 2004, 109(21):2572-2580.
54. Moscoso I., Centeno A., Lopez E., Rodriguez-Barbosa J.I., Santamarina I., Filgueira P., Sanchez M.J., Dominguez- Perles R., Penuelas-Rivas G., Domenech N. Differentiation in vitro of primary and immortalized porcine mesenchymal stem cells into cardiomyocytes for cell transplantationss. Transplant. Proc. 2005, 37(1):481-482.
55. NIH National Institutes of Health, Morbidity and Mortality 2000, NIH, Washington, DC.
56. Norol F., Merlet P., Isnard R., Sebillon P., Bonnet N., Cailliot C., Carrion C., Ribeiro M., Charlotte F., Pradeau P. Influence of mobilized stem cells on myocardial infarct repair in a nonhuman primate model. Blood 2003, 102(13):4361-4368.
57. Ohtsuka M., Takano H., Zou Y., Toko H., Akazawa H., Qin Y., Suzuki M., Hasegawa H., Nakaya H., Komuro I. Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization. Faseb J. 2004, 18(7):851-853.
58. Orlic D., Kajstura J., Chimenti S., Limana F., Jakoniuk I., Quaini F., Nadal-Ginard B., Bodine D.M., Leri A., Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc. Natl Acad. Sci. USA 2001, 98(18):10344-10349.
59. Orlic D., Kajstura J., Chimenti S., Jakoniuk I., Anderson S.M., Li B., Pickel J., McKay R., Nadal-Ginard B., Bodine D.M. Bone marrow cells regenerate infarcted myocardium. Nature 2001, 410(6829):701-705..
60. Oswald J., Boxberger S., Jorgensen B., Feldmann S., Ehninger G., Bornhauser M., Werner C. Mesenchymal stem cells can be differentiated into endothelial cells. in vitro. Stem Cells 2004, 22(3):377-384.
61. Ozturk M.A., Guven G.S., Haznedaroglu I.C. How hematopoietic stem cells know and act in cardiac microenvironment for stem cell plasticity? Impact of local renin-angiotensin systems. Med. Hypotheses 2004, 63(5):866-874.
62. Peled A., Kollet O., Ponomaryov T., Petit I., Franitza S., Grabovsky V., Slav M.M., Nagler A., Lider O., Alon R. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34() cells: role in transendothelial/stromal migration and engraftm. Blood 2000, 95(11):3289-3296.
63. Perin E.C., Silva G.V. Stem cell therapy for cardiac diseases. Curr. Opin. Hematol. 2004, 11(6):399-403.
64. Pittenger M.F., Martin B.J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 2004, 95(1):9-20.
65. Pompilio G., Cannata A., Peccatori F., Bertolini F., Nascimbene A., Capogrossi M.C., Biglioli P. Autologous peripheral blood stem cell transplantation for myocardial regeneration: a novel strategy for cell collection and surgical injection. Ann. Thorac. Surg. 2004, 78(5):1808-1812.
66. Powell T.M., Paul J.D., Hill J.M., Thompson M., Benjamin M., Rodrigo M., McCoy J.P., Read E.J., Khuu H.M., Leitman S.F. Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 2005, 25(2):296-301.
67. Quaini F., Urbanek K., Beltrami A.P., Finato N., Beltrami C.A., Nadal-Ginard B., Kajstura J., Leri A., Anversa P. Chimerism of the transplanted heart. N. Engl. J. Med. 2002, 346(1):5-15.
68. Reyes M., Dudek A., Jahagirdar B., Koodie L., Marker P.H., Verfaillie C.M. Origin of endothelial progenitors in human postnatal bone marrow. J. Clin. Invest. 2002, 109(3):337-346.
69. Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cell 1978, 4(1-2):7-25.
70. Schwartz R.E., Reyes M., Koodie L., Jiang Y., Blackstad M., Lund T., Lenvik T., Johnson S., Hu W.S., Verfaillie C.M. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J. Clin. Invest. 2002, 109(10):1291-1302.
71. Stamm C., Westphal B., Kleine H.D., Petzsch M., Kittner C., Klinge H., Schumichen C., Nienaber C.A., Freund M., Steinhoff G. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 2003, 361(9351):45-46.
72. Stocum D.L. Stem cells in regenerative biology and medicine. Wound Repair Regen. 2001, 9(6):429-442.
73. Theise N.D., Nimmakayalu M., Gardner R., Illei P.B., Morgan G., Teperman L., Henegariu O., Krause D.S. Liver from bone marrow in humans. Hepatology 2000, 32(1):11-16.
74. Tomita S., Li R.K., Weisel R.D., Mickle D.A., Kim E.J., Sakai T., Jia Z.Q. Autologoustransplantation of bone marrow cells improves damaged heart function. Circulation 1999, 100(19 Suppl):II247-II256.
75. Ueno H., Sakita-Ishikawa M., Morikawa Y., Nakano T., Kitamura T., Saito M. A stromal cell-derived membrane protein that supports hematopoietic stem cells. Nat. Immunol. 2003, 4(5):457-463.
76. Valgimigli M., Rigolin G.M., Cittanti C., Malagutti P., Curello S., Percoco G., Bugli A.M., Della Porta M., Bragotti L.Z., Ansani L. Use of granulocyte-colony stimulating factor during acute myocardial infarction to enhance bone marrow stem cell mobilization in humans: clinical and angiogra. Eur. Heart J. 2005, 26(18):1838-1845.
77. Vandervelde S., van Luyn M.J., Tio R.A., Harmsen M.C. Signaling factors in stem cell-mediated repair of infarcted myocardium. J.Mol. Cell Cardiol. 2005, 39(2):363-376.
78. Weissman I.L. Translating stem and progenitor cell biology to the clinic: barriers and opportunities. Science 2000, 287(5457):1442-1446.
79. Woldbaek P.R., Hoen I.B., Christensen G., Tonnessen T. Gene expression of colony-stimulating factors and stem cell factor after myocardial infarction in the mouse. Acta Physiol. Scand. 2002, 175(3):173-181.
80. Wollert K.C., Meyer G.P., Lotz J., Ringes-Lichtenberg S., Lippolt P., Breidenbach C., Fichtner S., Korte T., Hornig B., Messinger D. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004, 364(9429):141-148.
81. Woodbury D., Schwarz E.J., Prockop D.J., Black I.B. Adult rat and human bone marrow stromal cells differentiate into neurons. J. Neurosci. Res. 2000, 61(4):364-370.
82. Yoon J., Min B.G., Kim Y.H., Shim W.J., Ro Y.M., Lim D.S. Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model. Acta Cardiol. 2005, 60(3):277-284.
83. Zaffran S., Frasch M. Early signals in cardiac development. Circ. Res. 2002, 91(6):457-469.
84. Zhang J., Niu C., Ye L., Huang H., He X., Tong W.G., Ross J., Haug J., Johnson T., Feng J.Q. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003, 425(6960):836-841.