Off-rate screening for selection of high-affinity anti-drug antibodies

Analytical Biochemistry

Volumn 441, Issue 2, 2013, Pages 208-213

  Ylera, Francisco ^a   Harth, Stefan ^a   Waldherr, Dirk ^a   Frisch, Christian ^a   Knappik, Achim ^a  

^a Division of MorphoSys   (Germany)

Author keywords

Affinity screening; Anti idiotype; Biolayer interferometry; Cetuximab; HuCAL; Trastuzumab

Indexed keywords

ANTIGENS; ESCHERICHIA COLI; MONOCLONAL ANTIBODIES; PHAGE DISPLAY;

ANTI-IDIOTYPIC ANTIBODIES; CETUXIMAB; CLINICAL DEVELOPMENT; HUCAL; IDIOTYPE; RECOMBINANT ANTIBODY; THERAPEUTIC ANTIBODIES; TRASTUZUMAB;

CHEMICAL DETECTION;

BACTERIUM LYSATE; CETUXIMAB; DRUG ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; TRASTUZUMAB;

ANTIBODY AFFINITY; ANTIBODY LIBRARY; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; SENSOR;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

AFFINITY SCREENING; ANTI-IDIOTYPE; BIOLAYER INTERFEROMETRY; CETUXIMAB; HUCAL; TRASTUZUMAB;

ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIBODY AFFINITY; CLONING, MOLECULAR; ESCHERICHIA COLI; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; PEPTIDE LIBRARY;

EID: 84882783415     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.07.025     Document Type: Article

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