Parallel kinetic analysis and affinity determination of hundreds of monoclonal antibodies using the ProteOn XPR36

Analytical Biochemistry

Volumn 383, Issue 1, 2008, Pages 52-60

  Nahshol, Oded ^a   Bronner, Vered ^a   Notcovich, Ariel ^a   Rubrecht, Laetitia ^b   Laune, Daniel ^b   Bravman, Tsafrir ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b CNRS   (France)

Author keywords

High throughput screening; IL 12; Monoclonal antibodies; ProteOn XPR36; SPR

Indexed keywords

ANTIGENS; BIOCHEMISTRY; THROUGHPUT;

AFFINITY CONSTANTS; HIGH THROUGHPUT SCREENING; HUMAN INTERLEUKIN; IL-12; PHARMACEUTICAL COMPANY; PROTEIN INTERACTION; PROTEON XPR36; THERAPEUTIC APPLICATION;

MONOCLONAL ANTIBODIES;

HEMOGLOBIN VARIANT; INTERLEUKIN 12; MONOCLONAL ANTIBODY;

ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIBODY SCREENING; ANTIBODY SPECIFICITY; ARTICLE; CROSS REACTION; KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BIOSENSING TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYBRIDOMAS; INTERLEUKIN-12; KINETICS; MICE; MICE, INBRED BALB C; MODELS, THEORETICAL;

EID: 53049105640     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2008.08.017     Document Type: Article

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