Kinetic screening of antibodies from crude hybridoma samples using Biacore

Analytical Biochemistry

Volumn 325, Issue 2, 2004, Pages 301-307

  Canziani, Gabriela A ^a   Klakamp, Scott ^b   Myszka, David G ^a  

^a UNIVERSITY OF UTAH   (United States)

^b Abgenix Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; KINETICS; RATE CONSTANTS; SCREENING; SURFACE PLASMON RESONANCE;

CONCENTRATION MEASUREMENT; DATA ANALYSIS PROTOCOL; IDENTICAL CONDITIONS; INTERACTION MODEL; KINETIC RATE CONSTANTS; SCREENING METHODS; SCREENING PROTOCOL; SURFACE PLASMON RESONANCE BIOSENSOR;

ANTIBODIES;

IMMUNOGLOBULIN FC FRAGMENT; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY SCREENING; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; AUTOANALYSIS; BINDING KINETICS; BIOSENSOR; CONTROLLED STUDY; HUMAN; HYBRIDOMA; NONHUMAN; PRIORITY JOURNAL; SUPERNATANT; SURFACE PLASMON RESONANCE;

EID: 1642578938     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2003.11.004     Document Type: Article

References (20)

1. Milstein C. The hybridoma revolution: an offshoot of basic research. Biossays. 21:1999;966-973.
2. Souriau C., Hudson P.J. Recombinant antibodies for cancer diagnosis and therapy. Expert Opin. Biol. Ther. 3:2003;305-318.
3. Karlsson R., Michaelsson A., Mattsson L. Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. J. Immunol. Methods. 145:1991;229-240.
4. Karlsson R., Fägerstam L., Nilshans H., Persson B. Analysis of active antibody concentration. Separation of affinity and concentration parameters. J. Immunol. Methods. 166:1993;75-84.
5. Daiss J.L., Scalice E.R. Epitope Mapping on BIAcore: theoretical and practical considerations. Methods. 6:1994;143-156.
6. Rich R.L., Myszka D.G. Survey of the year 2000 commercial optical biosensor literature. J. Mol. Recognit. 14:2001;273-294.
7. Rich R.L., Myszka D.G. Survey of the year 2001 commercial optical biosensor literature. J. Mol. Recognit. 15:2002;352-376.
8. Laricchia Robbio L., Uboldi P., Marcovina S., Revoltella R.P., Catapano A.L. Epitope mapping of apolipoprotein B-100 using surface plasmon resonance-based biosensor. Biosensors and Bioelectronics. 16:2001;963-969.
9. Frank D.W., Vallis A., Wiener-Kronish J.P., Roy-Burman A., Spack E.G., Mullaney B.P., Megdoud M., Marks J.D., Fritz R., Sawa T. Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV. J. Infect. Dis. 186:2002;64-73.
10. Jone D.W., Nicholls P.J., Donohoe S., Gallimore M.J., Winter M. Antibodies to factor XII are distinct from antibodies to prothrombin in patients with the anti-phospholipid syndrome. Thromb. Haemost. 87:2002;426-430.
11. Zhu Z., Hattori K., Zhang H., Jimenez X., Ludwig D.L., Dias S., Kussie P., Koo H., Kim H.J., Lu D., Liu M., Tejada R., Friedrich M., Bohlen P., Witte L., Rafii S. Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity. Leukemia. 17:2003;604-611.
12. Takacs M.A., Jacobs S.J., Bordens R.M., Swanson S.J. Detection and characterization of antibodies to PEG-IFN-alpha2b using surface plasmon resonance. J. Interferon Cytokine Res. 19:1999;781-789.
13. Ohkura N., Soe G., Kohno I., Kumeda K., Wada H., Kamikubo Y., Shiku H., Kato H. Monoclonal antibody specific for tissue factor pathway inhibitor-factor Xa complex: its characterization and application to plasmas from patients with disseminated intravascular coagulation and predisseminated intravascular coagulation. Blood Coagul. Fibrinolysis. 10:1999;309-319.
14. Spalter S.H., Kaveri S.V., Bonnin E., Mani J.C., Cartron J.P., Kazatchkine M.D. Normal human serum contains natural antibodies reactive with autologous ABO blood group antigens. Blood. 93:1999;4418-4424.
15. Pei R., Cui X., Yang X., Wang E. Real-time immunoassay of antibody activity in serum by surface plasmon resonance. Talanta. 53:2000;481-488.
16. Mendez M.J., Green L.L., Corvalan J.R., Jia X.C., Maynard-Currie C.E., Yang X.D., Gallo M.L., Louie D.M., Lee D.V., Erickson K.L., Luna J., Roy C.M., Abderrahim H., Kirschenbaum F., Noguchi M., Smith D.H., Fukushima A., Hales J.F., Klapholz S., Finer M.H., Davis C.G., Zsebo K.M., Jakobovits A. Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice. Nat. Genet. 15:1997;146-156.
17. Johnsson B., Löfås S., Lindquist G. Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors. Anal. Biochem. 198:1991;268-277.
18. Jönsson U., Fägerstam L., Ivarsson B., Johnsson B., Karlsson R., Lundh K., Löfås S., Persson B., Roos H., Rönnberg I.et al. Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology. Biotechniques. 11:1991;620-627.
19. Myszka D.G. Improving biosensor analysis. J. Mol. Recognit. 12:1999;279-284.
20. Myszka D.G., Morton T.A. CLAMP: a biosensor kinetic data analysis program. Trends Biochem. Sci. 23:1998;149-150.