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Volumn 38, Issue 1, 2008, Pages 47-56

Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase

Author keywords

JNK; Oncogenic ras p21; Phosphorylation; raf; raf Ser259; raf Ser338

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P21; RAF PROTEIN; RAS PROTEIN; SERINE; STRESS ACTIVATED PROTEIN KINASE;

EID: 40049106639     PISSN: 00917370     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (24)
  • 1
    • 23844542139 scopus 로고    scopus 로고
    • Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins
    • Pincus MR. Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins. Front Biosci 2004;9:3486-3509.
    • (2004) Front Biosci , vol.9 , pp. 3486-3509
    • Pincus, M.R.1
  • 2
    • 0033950650 scopus 로고    scopus 로고
    • ras-p21-Induced cell transformation: Unique signal transduction pathways and implications for the design of new chemotherapeutic agents
    • Pincus MR, Brandt-Rauf PW, Michl J, Friedman FK. ras-p21-Induced cell transformation: unique signal transduction pathways and implications for the design of new chemotherapeutic agents. Cancer Invest 2000;18:39-50.
    • (2000) Cancer Invest , vol.18 , pp. 39-50
    • Pincus, M.R.1    Brandt-Rauf, P.W.2    Michl, J.3    Friedman, F.K.4
  • 3
    • 0028970732 scopus 로고
    • Complexes of ras-p21 with jun-n-kinase and c-jun proteins
    • Adler V, Pincus MR, Brandt-Rauf PW, Ronai Z. Complexes of ras-p21 with jun-n-kinase and c-jun proteins. PNAS USA 1995;92:10585-10589.
    • (1995) PNAS USA , vol.92 , pp. 10585-10589
    • Adler, V.1    Pincus, M.R.2    Brandt-Rauf, P.W.3    Ronai, Z.4
  • 6
    • 0022319149 scopus 로고
    • ras Proteins can induce meiosis in Xenopus oocytes
    • Birchmeier C, Broek D, Wigler M. ras Proteins can induce meiosis in Xenopus oocytes. Cell 1985;43:615-621.
    • (1985) Cell , vol.43 , pp. 615-621
    • Birchmeier, C.1    Broek, D.2    Wigler, M.3
  • 7
    • 0023117310 scopus 로고
    • Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins
    • Deshpande AK, Kung H-F. Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins. Mol Cell Biol 1987;7:1285-1288.
    • (1987) Mol Cell Biol , vol.7 , pp. 1285-1288
    • Deshpande, A.K.1    Kung, H.-F.2
  • 10
    • 0038697566 scopus 로고    scopus 로고
    • Raf proteins and cancer: B-raf is identified as a mutational target
    • Mercer KE, Pritchard CA. Raf proteins and cancer: b-raf is identified as a mutational target. Biochim Biophys Acta 2003;1653:25-40.
    • (2003) Biochim Biophys Acta , vol.1653 , pp. 25-40
    • Mercer, K.E.1    Pritchard, C.A.2
  • 13
    • 40049088732 scopus 로고    scopus 로고
    • Anticancer peptides from the ras-p21 and p53 proteins
    • RM Mohan, Ed Global Research Network Pub, Kerala, India, in press
    • Pincus MR, Michl J, Bowne W, Zenilman M. Anticancer peptides from the ras-p21 and p53 proteins. In: Research Advances in Cancer (RM Mohan, Ed) Global Research Network Pub, Kerala, India, 2007; in press.
    • (2007) Research Advances in Cancer
    • Pincus, M.R.1    Michl, J.2    Bowne, W.3    Zenilman, M.4
  • 14
    • 0141452187 scopus 로고    scopus 로고
    • Peptides, designed from molecular modeling studies of the ras-p21 protein, induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth
    • Kanovsky M, Michl J, Botzolaki G, Morin J, Kovac C, Chunh D, Friedman FK, Pincus MR. Peptides, designed from molecular modeling studies of the ras-p21 protein, induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth. Cancer Chemother Pharmacol. 2003;52:202-208.
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. 202-208
    • Kanovsky, M.1    Michl, J.2    Botzolaki, G.3    Morin, J.4    Kovac, C.5    Chunh, D.6    Friedman, F.K.7    Pincus, M.R.8
  • 15
    • 0036637644 scopus 로고    scopus 로고
    • Identification of the site of inhibition of mitogenic signaling by oncogenic ras-p21 by a ras effector peptide
    • Chie L, Friedman, FK, Kung H-F, Lim MCM, Chung DL, Pincus MR. Identification of the site of inhibition of mitogenic signaling by oncogenic ras-p21 by a ras effector peptide. J Protein Chem 2002;21:367-369.
    • (2002) J Protein Chem , vol.21 , pp. 367-369
    • Chie, L.1    Friedman, F.K.2    Kung, H.-F.3    Lim, M.C.M.4    Chung, D.L.5    Pincus, M.R.6
  • 16
    • 33744503401 scopus 로고    scopus 로고
    • Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic ras-p21 in Xenopus oocytes
    • Qu Y, Adler V, Chu T, Platica O, Michl J, Pestka S, Izotova L, Boutjdir M, Pincus MR. Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic ras-p21 in Xenopus oocytes. Front Biosci 2006;11:2420-2427.
    • (2006) Front Biosci , vol.11 , pp. 2420-2427
    • Qu, Y.1    Adler, V.2    Chu, T.3    Platica, O.4    Michl, J.5    Pestka, S.6    Izotova, L.7    Boutjdir, M.8    Pincus, M.R.9
  • 17
    • 34547702362 scopus 로고    scopus 로고
    • Dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type- but not by oncogenic-ras-p21 protein
    • Qu Y, Adler V, Izotova L, Pestka S, Bowne W, Michl J, Boutjdir M, Friedman FK, Pincus MR. Dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type- but not by oncogenic-ras-p21 protein. Front Biosci 2007;12,5089-5097.
    • (2007) Front Biosci , vol.12 , pp. 5089-5097
    • Qu, Y.1    Adler, V.2    Izotova, L.3    Pestka, S.4    Bowne, W.5    Michl, J.6    Boutjdir, M.7    Friedman, F.K.8    Pincus, M.R.9
  • 18
    • 0037294199 scopus 로고    scopus 로고
    • Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis
    • Yuryev A, Wennogle LP Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. Genomics 2003;81;112-125.
    • (2003) Genomics , vol.81 , pp. 112-125
    • Yuryev, A.1    Wennogle, L.P.2
  • 20
    • 0036236897 scopus 로고    scopus 로고
    • Cyclic AMP-dependent kinase regulates raf-1 kinase mainly by phosphorylation of serine 259
    • Dhillon AS, Pollock C, Steen H, Mischak H, Kolch W. Cyclic AMP-dependent kinase regulates raf-1 kinase mainly by phosphorylation of serine 259. Mol Cell Biol 2002;22:3237-3246.
    • (2002) Mol Cell Biol , vol.22 , pp. 3237-3246
    • Dhillon, A.S.1    Pollock, C.2    Steen, H.3    Mischak, H.4    Kolch, W.5
  • 24
    • 0033607633 scopus 로고    scopus 로고
    • Phosphorylation and regulation of RAF by Akt (protein kinase B)
    • Zimmerman S, Moelling, K. Phosphorylation and regulation of RAF by Akt (protein kinase B) Science 1999;26:1741-1744.
    • (1999) Science , vol.26 , pp. 1741-1744
    • Zimmerman, S.1    Moelling, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.