-
1
-
-
23844542139
-
Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins
-
Pincus MR. Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins. Front Biosci 2004;9:3486-3509.
-
(2004)
Front Biosci
, vol.9
, pp. 3486-3509
-
-
Pincus, M.R.1
-
2
-
-
0033950650
-
ras-p21-Induced cell transformation: Unique signal transduction pathways and implications for the design of new chemotherapeutic agents
-
Pincus MR, Brandt-Rauf PW, Michl J, Friedman FK. ras-p21-Induced cell transformation: unique signal transduction pathways and implications for the design of new chemotherapeutic agents. Cancer Invest 2000;18:39-50.
-
(2000)
Cancer Invest
, vol.18
, pp. 39-50
-
-
Pincus, M.R.1
Brandt-Rauf, P.W.2
Michl, J.3
Friedman, F.K.4
-
3
-
-
0028970732
-
Complexes of ras-p21 with jun-n-kinase and c-jun proteins
-
Adler V, Pincus MR, Brandt-Rauf PW, Ronai Z. Complexes of ras-p21 with jun-n-kinase and c-jun proteins. PNAS USA 1995;92:10585-10589.
-
(1995)
PNAS USA
, vol.92
, pp. 10585-10589
-
-
Adler, V.1
Pincus, M.R.2
Brandt-Rauf, P.W.3
Ronai, Z.4
-
4
-
-
0029789849
-
Activation of c-jun nh2 kinase by uv irradiation is dependent on p21ras
-
Adler V, Pincus MR, Polatskaya A, Montano X, Friedman FK, Ronai Z. Activation of c-jun nh2 kinase by uv irradiation is dependent on p21ras. J Biol Chem 1996;271,23304-23309.
-
(1996)
J Biol Chem
, vol.271
, pp. 23304-23309
-
-
Adler, V.1
Pincus, M.R.2
Polatskaya, A.3
Montano, X.4
Friedman, F.K.5
Ronai, Z.6
-
5
-
-
17944371722
-
Differences in patterns of activation of map kinases induced by oncogenic ras-p21 and insulin in oocytes
-
Ranginwale M, Smith S, Flom J, Chie L, Kanovsky M, Chung D, Friedman FK, Robinson RC, Brandt-Rauf PW, Yamaizumi Z, Michl J, Pincus MR. Differences in patterns of activation of map kinases induced by oncogenic ras-p21 and insulin in oocytes. Exp Cell Res 2001;269:162-169.
-
(2001)
Exp Cell Res
, vol.269
, pp. 162-169
-
-
Ranginwale, M.1
Smith, S.2
Flom, J.3
Chie, L.4
Kanovsky, M.5
Chung, D.6
Friedman, F.K.7
Robinson, R.C.8
Brandt-Rauf, P.W.9
Yamaizumi, Z.10
Michl, J.11
Pincus, M.R.12
-
6
-
-
0022319149
-
ras Proteins can induce meiosis in Xenopus oocytes
-
Birchmeier C, Broek D, Wigler M. ras Proteins can induce meiosis in Xenopus oocytes. Cell 1985;43:615-621.
-
(1985)
Cell
, vol.43
, pp. 615-621
-
-
Birchmeier, C.1
Broek, D.2
Wigler, M.3
-
7
-
-
0023117310
-
Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins
-
Deshpande AK, Kung H-F. Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins. Mol Cell Biol 1987;7:1285-1288.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 1285-1288
-
-
Deshpande, A.K.1
Kung, H.-F.2
-
8
-
-
0034033611
-
Induction of oocyte maturation by jun-n-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-mek signal transduction pathway
-
Chie L, Amar S, Kung H-F, Lin MCM, Chen H, Chung D, Adler V, Ronai Z, Friedman FK, Robinson RC, Kovac C, Brandt-Rauf PW, Yamaizumi Z, Michl J, Pincus MR. Induction of oocyte maturation by jun-n-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-mek signal transduction pathway. Cancer Chemother Pharmacol 2000;45:441-449.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 441-449
-
-
Chie, L.1
Amar, S.2
Kung, H.-F.3
Lin, M.C.M.4
Chen, H.5
Chung, D.6
Adler, V.7
Ronai, Z.8
Friedman, F.K.9
Robinson, R.C.10
Kovac, C.11
Brandt-Rauf, P.W.12
Yamaizumi, Z.13
Michl, J.14
Pincus, M.R.15
-
9
-
-
23844438832
-
Functional interactions of raf and mek with jun-n-terminal kinase (JNK) result in a positive feedback pathway loop on the oncogenic ras signaling pathway
-
Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung H-F, Lin M, Friedman FK, Chie L, Chung DL, Boutjdir M, Pincus MR. Functional interactions of raf and mek with jun-n-terminal kinase (JNK) result in a positive feedback pathway loop on the oncogenic ras signaling pathway. Biochemistry 2005;44:10784-10795.
-
(2005)
Biochemistry
, vol.44
, pp. 10784-10795
-
-
Adler, V.1
Qu, Y.2
Smith, S.J.3
Izotova, L.4
Pestka, S.5
Kung, H.-F.6
Lin, M.7
Friedman, F.K.8
Chie, L.9
Chung, D.L.10
Boutjdir, M.11
Pincus, M.R.12
-
10
-
-
0038697566
-
Raf proteins and cancer: B-raf is identified as a mutational target
-
Mercer KE, Pritchard CA. Raf proteins and cancer: b-raf is identified as a mutational target. Biochim Biophys Acta 2003;1653:25-40.
-
(2003)
Biochim Biophys Acta
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
11
-
-
0022620602
-
Synthesis and expression of a synthetic gene for the activated human c-Ha-ras protein
-
Miura K, Inouye Y, Nakamor H, Iwai S, Ohtsuka E, Ikehara M, Noguchi S, Nishimura S. Synthesis and expression of a synthetic gene for the activated human c-Ha-ras protein. Jpn J Cancer Res 1986;77:45-51.
-
(1986)
Jpn J Cancer Res
, vol.77
, pp. 45-51
-
-
Miura, K.1
Inouye, Y.2
Nakamor, H.3
Iwai, S.4
Ohtsuka, E.5
Ikehara, M.6
Noguchi, S.7
Nishimura, S.8
-
12
-
-
0034685656
-
Role of raf-1 conserved region 2 in regulation of ras-dependent raf-1 activation
-
Sendoh H, Hu C-D, Wu D, Song C, Yamawaki-Kataoka Y, Kotani J, Okada T, Shima F, Kariya K-I, Kataoka T. Role of raf-1 conserved region 2 in regulation of ras-dependent raf-1 activation. Biochem Biophys Res Commun 2000;271:596-602.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 596-602
-
-
Sendoh, H.1
Hu, C.-D.2
Wu, D.3
Song, C.4
Yamawaki-Kataoka, Y.5
Kotani, J.6
Okada, T.7
Shima, F.8
Kariya, K.-I.9
Kataoka, T.10
-
13
-
-
40049088732
-
Anticancer peptides from the ras-p21 and p53 proteins
-
RM Mohan, Ed Global Research Network Pub, Kerala, India, in press
-
Pincus MR, Michl J, Bowne W, Zenilman M. Anticancer peptides from the ras-p21 and p53 proteins. In: Research Advances in Cancer (RM Mohan, Ed) Global Research Network Pub, Kerala, India, 2007; in press.
-
(2007)
Research Advances in Cancer
-
-
Pincus, M.R.1
Michl, J.2
Bowne, W.3
Zenilman, M.4
-
14
-
-
0141452187
-
Peptides, designed from molecular modeling studies of the ras-p21 protein, induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth
-
Kanovsky M, Michl J, Botzolaki G, Morin J, Kovac C, Chunh D, Friedman FK, Pincus MR. Peptides, designed from molecular modeling studies of the ras-p21 protein, induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth. Cancer Chemother Pharmacol. 2003;52:202-208.
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 202-208
-
-
Kanovsky, M.1
Michl, J.2
Botzolaki, G.3
Morin, J.4
Kovac, C.5
Chunh, D.6
Friedman, F.K.7
Pincus, M.R.8
-
15
-
-
0036637644
-
Identification of the site of inhibition of mitogenic signaling by oncogenic ras-p21 by a ras effector peptide
-
Chie L, Friedman, FK, Kung H-F, Lim MCM, Chung DL, Pincus MR. Identification of the site of inhibition of mitogenic signaling by oncogenic ras-p21 by a ras effector peptide. J Protein Chem 2002;21:367-369.
-
(2002)
J Protein Chem
, vol.21
, pp. 367-369
-
-
Chie, L.1
Friedman, F.K.2
Kung, H.-F.3
Lim, M.C.M.4
Chung, D.L.5
Pincus, M.R.6
-
16
-
-
33744503401
-
Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic ras-p21 in Xenopus oocytes
-
Qu Y, Adler V, Chu T, Platica O, Michl J, Pestka S, Izotova L, Boutjdir M, Pincus MR. Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic ras-p21 in Xenopus oocytes. Front Biosci 2006;11:2420-2427.
-
(2006)
Front Biosci
, vol.11
, pp. 2420-2427
-
-
Qu, Y.1
Adler, V.2
Chu, T.3
Platica, O.4
Michl, J.5
Pestka, S.6
Izotova, L.7
Boutjdir, M.8
Pincus, M.R.9
-
17
-
-
34547702362
-
Dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type- but not by oncogenic-ras-p21 protein
-
Qu Y, Adler V, Izotova L, Pestka S, Bowne W, Michl J, Boutjdir M, Friedman FK, Pincus MR. Dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type- but not by oncogenic-ras-p21 protein. Front Biosci 2007;12,5089-5097.
-
(2007)
Front Biosci
, vol.12
, pp. 5089-5097
-
-
Qu, Y.1
Adler, V.2
Izotova, L.3
Pestka, S.4
Bowne, W.5
Michl, J.6
Boutjdir, M.7
Friedman, F.K.8
Pincus, M.R.9
-
18
-
-
0037294199
-
Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis
-
Yuryev A, Wennogle LP Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. Genomics 2003;81;112-125.
-
(2003)
Genomics
, vol.81
, pp. 112-125
-
-
Yuryev, A.1
Wennogle, L.P.2
-
19
-
-
0026527191
-
Evidence that the ras-oncogene-encoded 21 protein induces oocyte maturation via activation of protein kinase C
-
Chung DL, Brandt-Rauf PW, Weinstein IB, Nishimura S, Yamaizumi Z, Murphy RB, Pincus MR. Evidence that the ras-oncogene-encoded 21 protein induces oocyte maturation via activation of protein kinase C. PNAS USA 1992;89,1993-1996.
-
(1992)
PNAS USA
, vol.89
, pp. 1993-1996
-
-
Chung, D.L.1
Brandt-Rauf, P.W.2
Weinstein, I.B.3
Nishimura, S.4
Yamaizumi, Z.5
Murphy, R.B.6
Pincus, M.R.7
-
20
-
-
0036236897
-
Cyclic AMP-dependent kinase regulates raf-1 kinase mainly by phosphorylation of serine 259
-
Dhillon AS, Pollock C, Steen H, Mischak H, Kolch W. Cyclic AMP-dependent kinase regulates raf-1 kinase mainly by phosphorylation of serine 259. Mol Cell Biol 2002;22:3237-3246.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3237-3246
-
-
Dhillon, A.S.1
Pollock, C.2
Steen, H.3
Mischak, H.4
Kolch, W.5
-
21
-
-
0034306451
-
Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association
-
Yip-Schneider MT, Miao W, Lin A, Barnard S, Tzivion G, Marshall MS. Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association Biochem J 2000;351:151-159.
-
(2000)
Biochem J
, vol.351
, pp. 151-159
-
-
Yip-Schneider, M.T.1
Miao, W.2
Lin, A.3
Barnard, S.4
Tzivion, G.5
Marshall, M.S.6
-
22
-
-
0034698027
-
Raf-1-associated protein phosphatase 2a as a positive regulator of kinase activation
-
Abraham D, Podar K, Pacher M, Kubicek M, Welzel N, Hemmings BA, Dilworth, SM, Mischak H, Kolch W, Baccarini M. Raf-1-associated protein phosphatase 2a as a positive regulator of kinase activation. J Biol Chem 2000;275;22300-22304.
-
(2000)
J Biol Chem
, vol.275
, pp. 22300-22304
-
-
Abraham, D.1
Podar, K.2
Pacher, M.3
Kubicek, M.4
Welzel, N.5
Hemmings, B.A.6
Dilworth, S.M.7
Mischak, H.8
Kolch, W.9
Baccarini, M.10
-
23
-
-
0027326410
-
Protein kinase C-alpha activates RAF-1 by direct phosphorylation
-
Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, Mischak H, Finkenzeller G, Marme D, Rapp UR. Protein kinase C-alpha activates RAF-1 by direct phosphorylation. Nature 1993;364:249-252.
-
(1993)
Nature
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
Hummel, R.4
Vahidi, H.5
Mischak, H.6
Finkenzeller, G.7
Marme, D.8
Rapp, U.R.9
-
24
-
-
0033607633
-
Phosphorylation and regulation of RAF by Akt (protein kinase B)
-
Zimmerman S, Moelling, K. Phosphorylation and regulation of RAF by Akt (protein kinase B) Science 1999;26:1741-1744.
-
(1999)
Science
, vol.26
, pp. 1741-1744
-
-
Zimmerman, S.1
Moelling, K.2
|