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Volumn 32, Issue 44, 2012, Pages 15511-15520

Loss of signal transducer and activator of transcription 3 (STAT3) signaling during elevated activity causes vulnerability in hippocampal neurons

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL) CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINOPYRIDINE; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM ION; CASPASE 3; K 252A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEURON SPECIFIC NUCLEAR PROTEIN; PROTEIN BAX; PROTEIN P53; RAPAMYCIN; ROSCOVITINE; SERINE; STAT3 PROTEIN; TETRODOTOXIN; UNCLASSIFIED DRUG;

EID: 84868159285     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2940-12.2012     Document Type: Article
Times cited : (24)

References (55)
  • 4
    • 0026512998 scopus 로고
    • K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity
    • Berg MM, Sternberg DW, Parada LF, Chao MV (1992) K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity. J Biol Chem 267:13-16.
    • (1992) J Biol Chem , vol.267 , pp. 13-16
    • Berg, M.M.1    Sternberg, D.W.2    Parada, L.F.3    Chao, M.V.4
  • 5
    • 77956648119 scopus 로고    scopus 로고
    • Signaling mechanisms regulating synapse formation and function in mental retardation
    • Boda B, Dubos A, Muller D (2010) Signaling mechanisms regulating synapse formation and function in mental retardation. Curr Opin Neurobiol 20:519-527.
    • (2010) Curr Opin Neurobiol , vol.20 , pp. 519-527
    • Boda, B.1    Dubos, A.2    Muller, D.3
  • 7
    • 0029943487 scopus 로고    scopus 로고
    • Insulin stimulates the serine phosphorylation of the signal transducer and activator of transcription (STAT3) isoform
    • Ceresa BP, Pessin JE (1996) Insulin stimulates the serine phosphorylation of the signal transducer and activator of transcription (STAT3) isoform. J Biol Chem 271:12121-12124.
    • (1996) J Biol Chem , vol.271 , pp. 12121-12124
    • Ceresa, B.P.1    Pessin, J.E.2
  • 8
    • 0030772458 scopus 로고    scopus 로고
    • STAT3 serine phosphorylation by ERK-dependent and-independent pathways negatively modulates its tyrosine phosphorylation
    • Chung J, Uchida E, Grammer TC, Blenis J (1997) STAT3 serine phosphorylation by ERK-dependent and-independent pathways negatively modulates its tyrosine phosphorylation. Mol Cell Biol 17:6508-6516.
    • (1997) Mol Cell Biol , vol.17 , pp. 6508-6516
    • Chung, J.1    Uchida, E.2    Grammer, T.C.3    Blenis, J.4
  • 9
    • 44649201117 scopus 로고    scopus 로고
    • Activity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrins
    • Cingolani LA, Thalhammer A, Yu LM, Catalano M, Ramos T, Colicos MA, Goda Y (2008) Activity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrins. Neuron 58:749-762.
    • (2008) Neuron , vol.58 , pp. 749-762
    • Cingolani, L.A.1    Thalhammer, A.2    Yu, L.M.3    Catalano, M.4    Ramos, T.5    Colicos, M.A.6    Goda, Y.7
  • 11
    • 33745734146 scopus 로고    scopus 로고
    • Homeostatic control of neural activity: From phenomenology to molecular design
    • Davis GW (2006) Homeostatic control of neural activity: from phenomenology to molecular design. Annu Rev Neurosci 29:307-323.
    • (2006) Annu Rev Neurosci , vol.29 , pp. 307-323
    • Davis, G.W.1
  • 12
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker T, Kovarik P (2000) Serine phosphorylation of STATs. Oncogene 19:2628-2637.
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 14
    • 70349838218 scopus 로고    scopus 로고
    • Cytokines and CNS development
    • Deverman BE, Patterson PH (2009) Cytokines and CNS development. Neuron 64:61-78.
    • (2009) Neuron , vol.64 , pp. 61-78
    • Deverman, B.E.1    Patterson, P.H.2
  • 15
    • 0032484019 scopus 로고    scopus 로고
    • CREB is a regulatory target for the protein kinase Akt/PKB
    • Du K, Montminy M (1998) CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem 273:32377-32379.
    • (1998) J Biol Chem , vol.273 , pp. 32377-32379
    • Du, K.1    Montminy, M.2
  • 16
    • 34447116951 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection
    • Dziennis S, Jia T, Rønnekleiv OK, Hurn PD, Alkayed NJ (2007) Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection. J Neurosci 27:7268-7274.
    • (2007) J Neurosci , vol.27 , pp. 7268-7274
    • Dziennis, S.1    Jia, T.2    Rønnekleiv, O.K.3    Hurn, P.D.4    Alkayed, N.J.5
  • 17
    • 0031438851 scopus 로고    scopus 로고
    • Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: A phenotype indistinguishable from Bax deletion
    • Easton RM, Deckwerth TL, Parsadanian AS, Johnson EM Jr (1997) Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion. J Neurosci 17:9656-9666.
    • (1997) J Neurosci , vol.17 , pp. 9656-9666
    • Easton, R.M.1    Deckwerth, T.L.2    Parsadanian, A.S.3    Johnson Jr., E.M.4
  • 18
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
    • Fernandes-Alnemri T, Litwack G, Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem 269:30761-30764.
    • (1994) J Biol Chem , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 20
    • 2342483179 scopus 로고    scopus 로고
    • Cyclindependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
    • Fu AK, Fu WY, Ng AK, Chien WW, Ng YP, Wang JH, Ip NY (2004) Cyclindependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity. Proc Natl Acad Sci U S A 101:6728-6733.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6728-6733
    • Fu, A.K.1    Fu, W.Y.2    Ng, A.K.3    Chien, W.W.4    Ng, Y.P.5    Wang, J.H.6    Ip, N.Y.7
  • 22
    • 1842505722 scopus 로고    scopus 로고
    • Basic mechanisms of partial epilepsies
    • Heinemann U (2004) Basic mechanisms of partial epilepsies. Curr Opin Neurol 17:155-159.
    • (2004) Curr Opin Neurol , vol.17 , pp. 155-159
    • Heinemann, U.1
  • 23
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • Huang EJ, Reichardt LF (2003) Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72:609-642.
    • (2003) Annu Rev Biochem , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 24
    • 0019050811 scopus 로고
    • Microtubule-associated proteins: A monoclonal antibody to MAP2 binds to differentiated neurons
    • Izant JG, McIntosh JR (1980) Microtubule-associated proteins: a monoclonal antibody to MAP2 binds to differentiated neurons. Proc Natl Acad Sci USA77:4741-4745.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 4741-4745
    • Izant, J.G.1    McIntosh, J.R.2
  • 25
    • 33749076673 scopus 로고    scopus 로고
    • SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
    • Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B (2006) SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127:125-137.
    • (2006) Cell , vol.127 , pp. 125-137
    • Jacinto, E.1    Facchinetti, V.2    Liu, D.3    Soto, N.4    Wei, S.5    Jung, S.Y.6    Huang, Q.7    Qin, J.8    Su, B.9
  • 26
    • 0032542211 scopus 로고    scopus 로고
    • Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)
    • Jain N, Zhang T, Fong SL, Lim CP, Cao X (1998) Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK). Oncogene 17:3157-3167.
    • (1998) Oncogene , vol.17 , pp. 3157-3167
    • Jain, N.1    Zhang, T.2    Fong, S.L.3    Lim, C.P.4    Cao, X.5
  • 27
    • 0033588229 scopus 로고    scopus 로고
    • Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
    • Jain N, Zhang T, Kee WH, Li W, Cao X (1999) Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. J Biol Chem 274:24392-24400.
    • (1999) J Biol Chem , vol.274 , pp. 24392-24400
    • Jain, N.1    Zhang, T.2    Kee, W.H.3    Li, W.4    Cao, X.5
  • 28
    • 66149171367 scopus 로고    scopus 로고
    • Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia
    • Jung JE, Kim GS, Narasimhan P, Song YS, Chan PH (2009) Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia. J Neurosci 29:7003-7014.
    • (2009) J Neurosci , vol.29 , pp. 7003-7014
    • Jung, J.E.1    Kim, G.S.2    Narasimhan, P.3    Song, Y.S.4    Chan, P.H.5
  • 29
    • 34250222419 scopus 로고    scopus 로고
    • Regulation of dendritic excitability by activity-dependent trafficking of the A-type K channel subunit Kv4.2 in hippocampal neurons
    • Kim J, Jung SC, Clemens AM, Petralia RS, Hoffman DA (2007) Regulation of dendritic excitability by activity-dependent trafficking of the A-type K channel subunit Kv4.2 in hippocampal neurons. Neuron 54:933-947.
    • (2007) Neuron , vol.54 , pp. 933-947
    • Kim, J.1    Jung, S.C.2    Clemens, A.M.3    Petralia, R.S.4    Hoffman, D.A.5
  • 30
    • 0029810181 scopus 로고    scopus 로고
    • Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
    • Kohn AD, Takeuchi F, Roth RA (1996) Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J Biol Chem 271:21920-21926.
    • (1996) J Biol Chem , vol.271 , pp. 21920-21926
    • Kohn, A.D.1    Takeuchi, F.2    Roth, R.A.3
  • 31
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE Jr (2002) Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3:651-662.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 32
    • 0006603039 scopus 로고    scopus 로고
    • Serine phosphorylation and negative regulation of Stat3 by JNK
    • Lim CP, Cao X (1999) Serine phosphorylation and negative regulation of Stat3 by JNK. J Biol Chem 274:31055-31061.
    • (1999) J Biol Chem , vol.274 , pp. 31055-31061
    • Lim, C.P.1    Cao, X.2
  • 33
    • 0035877595 scopus 로고    scopus 로고
    • Regulation of Stat3 activation by MEK kinase 1
    • Lim CP, Cao X (2001) Regulation of Stat3 activation by MEK kinase 1. J Biol Chem 276:21004-21011.
    • (2001) J Biol Chem , vol.276 , pp. 21004-21011
    • Lim, C.P.1    Cao, X.2
  • 34
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 37
    • 33748917421 scopus 로고    scopus 로고
    • A specific survival response in dopamine neurons at most risk in Parkinson's disease
    • Murase S, McKay RD (2006) A specific survival response in dopamine neurons at most risk in Parkinson's disease. J Neurosci 26:9750-9760.
    • (2006) J Neurosci , vol.26 , pp. 9750-9760
    • Murase, S.1    McKay, R.D.2
  • 38
    • 79957636752 scopus 로고    scopus 로고
    • In the newborn hippocampus, neurotrophin-dependent survival requires spontaneous activity and integrin signaling
    • Murase S, Owens DF, McKay RD (2011a) In the newborn hippocampus, neurotrophin-dependent survival requires spontaneous activity and integrin signaling. J Neurosci 31:7791-7800.
    • (2011) J Neurosci , vol.31 , pp. 7791-7800
    • Murase, S.1    Owens, D.F.2    McKay, R.D.3
  • 39
    • 79960953206 scopus 로고    scopus 로고
    • McKay RD (2011b) p53 controls neuronal death in the CA3 region of the newborn mouse hippocampus
    • Murase S, Poser SW, Joseph J, McKay RD (2011b) p53 controls neuronal death in the CA3 region of the newborn mouse hippocampus. Eur J Neurosci 34:374-381.
    • Eur J Neurosci , vol.34 , pp. 374-381
    • Murase, S.1    Poser, S.W.2    Joseph, J.3
  • 40
    • 33744925451 scopus 로고    scopus 로고
    • STAT3 as a downstream mediator of Trk signaling and functions
    • Ng YP, Cheung ZH, Ip NY (2006) STAT3 as a downstream mediator of Trk signaling and functions. J Biol Chem 281:15636-15644.
    • (2006) J Biol Chem , vol.281 , pp. 15636-15644
    • Ng, Y.P.1    Cheung, Z.H.2    Ip, N.Y.3
  • 42
    • 0032540252 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes
    • Oh H, Fujio Y, Kunisada K, Hirota H, Matsui H, Kishimoto T, Yamauchi-Takihara K (1998) Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes. J Biol Chem 273:9703-9710.
    • (1998) J Biol Chem , vol.273 , pp. 9703-9710
    • Oh, H.1    Fujio, Y.2    Kunisada, K.3    Hirota, H.4    Matsui, H.5    Kishimoto, T.6    Yamauchi-Takihara, K.7
  • 44
    • 77949418629 scopus 로고    scopus 로고
    • Three hypotheses for developmental defects that may underlie some forms of autism spectrum disorder
    • Rubenstein JL (2010) Three hypotheses for developmental defects that may underlie some forms of autism spectrum disorder. Curr Opin Neurol 23:118-123.
    • (2010) Curr Opin Neurol , vol.23 , pp. 118-123
    • Rubenstein, J.L.1
  • 45
    • 0037148523 scopus 로고    scopus 로고
    • Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult
    • Schweizer U, Gunnersen J, Karch C, Wiese S, Holtmann B, Takeda K, Akira S, Sendtner M (2002) Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. J Cell Biol 156:287-297.
    • (2002) J Cell Biol , vol.156 , pp. 287-297
    • Schweizer, U.1    Gunnersen, J.2    Karch, C.3    Wiese, S.4    Holtmann, B.5    Takeda, K.6    Akira, S.7    Sendtner, M.8
  • 46
    • 43649097642 scopus 로고    scopus 로고
    • Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity
    • Seeburg DP, Feliu-Mojer M, Gaiottino J, Pak DT, Sheng M (2008) Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity. Neuron 58:571-583.
    • (2008) Neuron , vol.58 , pp. 571-583
    • Seeburg, D.P.1    Feliu-Mojer, M.2    Gaiottino, J.3    Pak, D.T.4    Sheng, M.5
  • 47
    • 0026785441 scopus 로고
    • Subcellular segregation of two A-type K channel proteins in rat central neurons
    • Sheng M, Tsaur ML, Jan YN, Jan LY (1992) Subcellular segregation of two A-type K channel proteins in rat central neurons. Neuron 9:271-284.
    • (1992) Neuron , vol.9 , pp. 271-284
    • Sheng, M.1    Tsaur, M.L.2    Jan, Y.N.3    Jan, L.Y.4
  • 49
    • 0029790656 scopus 로고    scopus 로고
    • FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2
    • Tan Y, Rouse J, Zhang A, Cariati S, Cohen P, Comb MJ (1996) FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2. EMBO J 15:4629-4642.
    • (1996) EMBO J , vol.15 , pp. 4629-4642
    • Tan, Y.1    Rouse, J.2    Zhang, A.3    Cariati, S.4    Cohen, P.5    Comb, M.J.6
  • 50
    • 0034644523 scopus 로고    scopus 로고
    • Cellular signaling: Pivoting around PDK-1
    • Toker A, Newton AC (2000) Cellular signaling: pivoting around PDK-1. Cell 103:185-188.
    • (2000) Cell , vol.103 , pp. 185-188
    • Toker, A.1    Newton, A.C.2
  • 51
    • 34249936485 scopus 로고    scopus 로고
    • Homeostatic signaling: The positive side of negative feedback
    • Turrigiano G (2007) Homeostatic signaling: the positive side of negative feedback. Curr Opin Neurobiol 17:318-324.
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 318-324
    • Turrigiano, G.1
  • 52
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen Z, Zhong Z, Darnell JE Jr (1995) Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 54
    • 0024253427 scopus 로고
    • Single-channel analysis of four distinct classes of potassium channels in Drosophila muscle
    • Zagotta WN, Brainard MS, Aldrich RW (1988) Single-channel analysis of four distinct classes of potassium channels in Drosophila muscle. J Neurosci 8:4765-4779.
    • (1988) J Neurosci , vol.8 , pp. 4765-4779
    • Zagotta, W.N.1    Brainard, M.S.2    Aldrich, R.W.3
  • 55
    • 23044515099 scopus 로고    scopus 로고
    • Functions and mechanisms of retrograde neurotrophin signalling
    • Zweifel LS, Kuruvilla R, Ginty DD (2005) Functions and mechanisms of retrograde neurotrophin signalling. Nat Rev Neurosci 6:615-625.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 615-625
    • Zweifel, L.S.1    Kuruvilla, R.2    Ginty, D.D.3


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