Biophysical Specializations of Neurons that Encode Timing

The Senses: A Comprehensive Reference

Volumn 3, Issue , 2008, Pages 565-586

  Manis, P B ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Auditory system; Electrical excitability; Hearing; Ion channels; Potassium channels

Indexed keywords

EID: 84882457595     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012370880-9.00044-X     Document Type: Chapter

References (175)

1. Adam T.J., Finlayson P., Schwarz D.W. Membrane properties of principal neurons of the lateral superior olive. J. Neurophysiol. 2001, 86:922-934.
2. Adam T.J., Schwarz D.W., Finlayson P. Firing properties of chopper and delay neurons in the lateral superior olive of the rat. Exp. Brain Res. 1999, 124:489-502.
3. Adamson C.L., Reid M.A., Davis R.L. Opposite actions of brain-derived neurotrophic factor and neurotrophin-3 on firing features and ion channel composition of murine spiral ganglion neurons. J. Neurosci. 2002, 22:1385-1396.
4. Adamson C.L., Reid M.A., Mo Z.L., Bowne-English J., Davis R.L. Firing features and potassium channel content of murine spiral ganglion neurons vary with cochlear location. J. Comp. Neurol. 2002, 447:331-350.
5. Agmon-Snir H., Carr C.E., Rinzel J. The role of dendrites in auditory coincidence detection. Nature 1998, 393:268-272.
6. Alonso G., Widmer H. Clustering of Kv4.2 potassium channels in postsynaptic membrane of rat supraoptic neurons: an ultrastructural study. Neuroscience 1997, 77:617-621.
7. An W.F., Bowlby M.R., Betty M., Cao J., Ling H.P., Mendoza G., Hinson J.W., Strassle B.W., Trimmer J.S., Rhodes K.J. Modulation of A-type potassium channels by a family of calcium sensors. Nature 2000, 403:553-556.
8. h) in octopus cells of the mammalian cochlear nucleus. J. Neurophysiol. 2000, 84:806-817.
9. Bal R., Oertel D. Potassium currents in octopus cells of the mammalian cochlear nucleus. J. Neurophysiol. 2001, 86:2299-2311.
10. Banks M.I., Smith P.H. Intracellular recordings from neurobiotin-labeled cells in brain slices of the rat medial nucleus of the trapezoid body. J. Neurosci. 1992, 12:2819-2837.
11. h) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in auditory brain stem. J. Neurophysiol. 1993, 70:1420-1432.
12. Barnes-Davies M., Barker M.C., Osmani F., Forsythe I.D. Kv1 currents mediate a gradient of principal neuron excitability across the tonotopic axis in the rat lateral superior olive. Eur. J. Neurosci. 2004, 19:325-333.
13. Baro D.J., Levini R.M., Kim M.T., Willms A.R., Lanning C.C., Rodriguez H.E., Harris-Warrick R.M. Quantitative single-cell-reverse transcription-PCR demonstrates that A-current magnitude varies as a linear function of shal gene expression in identified stomatogastric neurons. J. Neurosci. 1997, 17:6597-6610.
14. 2+. Trends Neurosci. 2005, 28:422-428.
15. Bhattacharjee A., Gan L., Kaczmarek L.K. Localization of the Slack potassium channel in the rat central nervous system. J. Comp. Neurol. 2002, 454:241-254.
16. + channel Slick in the rat central nervous system. J. Comp. Neurol. 2005, 484:80-92.
17. Bortone D.S., Mitchell K., Manis P.B. Developmental time course of potassium channel expression in the rat cochlear nucleus. Hear. Res. 2006, 211:114-125.
18. + currents in rat atrial myocytes. J. Physiol. (Lond.) 1999, 517:407-420.
19. Brand A., Behrend O., Marquardt T., McAlpine D., Grothe B. Precise inhibition is essential for microsecond interaural time difference coding. Nature 2002, 417:543-547.
20. B receptors. Neuron 1998, 20:135-141.
21. + conductances with complementary functions in postsynaptic integration at a central auditory synapse. J. Neurosci. 1995, 15:8011-8022.
22. Brew H.M., Forsythe I.D. Systematic variation of potassium current amplitudes across the tonotopic axis of the rat medial nucleus of the trapezoid body. Hear. Res. 2005, 206:116-132.
23. Brew H.M., Hallows J.L., Tempel B.L. Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1. J. Physiol. 2003, 548:1-20.
24. Cai Y., Walsh E.J., McGee J. Mechanisms of onset responses in octopus cells of the cochlear nucleus: implications of a model. J. Neurophysiol. 1997, 78:872-883.
25. Caminos E., Vale C., Lujan R., Martinez-Galan J.R., Juiz J.M. Developmental regulation and adult maintenance of potassium channel proteins (Kv 1.1 and Kv 1.2) in the cochlear nucleus of the rat. Brain Res. 2005, 1056:118-131.
26. Caspary D.M., Backoff P.M., Finlayson P.G., Palombi P.S. Inhibitory inputs modulate discharge rate within frequency receptive fields of anteroventral cochlear nucleus neurons. J. Neurophysiol. 1994, 72:2124-2133.
27. Castellino R.C., Morales M.J., Strauss H.C., Rasmusson R.L. Time- and voltage-dependent modulation of a Kv1.4 channel by a beta-subunit (KvBeta3) cloned from ferret ventricle. Am. J. Physiol. 1995, 269:H385-H391.
28. Chen W.C., Davis R.L. Voltage-gated and two-pore-domain potassium channels in murine spiral ganglion neurons. Hear. Res. 2006, 222:89-99.
29. + channel activities in plants. from physiological to molecular aspects. J. Exp. Bot. 2004, 55:337-351.
30. + channels. Ann. N. Y. Acad. Sci. 1999, 868:233-285.
31. + channel densities in the soma and axon initial segment of subicular pyramidal neurons. J. Neurosci. 1996, 16:6676-6686.
32. Colbert C.M., Pan E. Ion channel properties underlying axonal action potential initiation in pyramidal neurons. Nat. Neurosci. 2002, 5:533-538.
33. Cook D.L., Schwindt P.C., Grande L.A., Spain W.J. Synaptic depression in the localization of sound. Nature 2003, 421:66-70.
34. Covey E., Casseday J.H. The monaural nuclei of the lateral lemniscus in an echolocating bat: parallel pathways for analyzing temporal features of sound. J. Neurosci. 1991, 11:3456-3470.
35. Dodson P.D., Barker M.C., Forsythe I.D. Two heteromeric Kv1 potassium channels differentially regulate action potential firing. J. Neurosci. 2002, 22:6953-6961.
36. Dodson P.D., Billups B., Rusznak Z., Szucs G., Barker M.C., Forsythe I.D. Presynaptic rat Kv1.2 channels suppress synaptic terminal hyperexcitability following action potential invasion. J. Physiol. 2003, 550:27-33.
37. + current. J. Neurosci. 2005, 25:363-371.
38. Ferragamo M.J., Oertel D. Octopus cells of the mammalian ventral cochlear nucleus sense the rate of depolarization. J. Neurophysiol. 2002, 87:2262-2270.
39. Fettiplace R., Fuchs P.A. Mechanisms of hair cell tuning. Annu. Rev. Physiol. 1999, 61:809-834.
40. Fitzakerley, J.L. and Quale, M. 2005. Differential expression of potassium channel Kv2.1 in the adult mouse cochlear nucleus. Association for Research in Otolaryngology, Midwinter Meeting, New Orleans, LA.
41. Fitzakerley J.L., Star K.V., Rinn J.L., Elmquist B.J. Expression of Shal potassium channel subunits in the adult and developing cochlear nucleus of the mouse. Hear. Res. 2000, 147:31-45.
42. Forsythe I.D., Barnes-Davies M. The binaural auditory pathway: membrane currents limiting multiple action potential generation in the rat medial nucleus of the trapezoid body. Proc. Biol. Sci. 1993, 251:143-150.
43. Francis H.W., Manis P.B. Effects of deafferentation on the electrophysiology of ventral cochlear nucleus neurons. Hear. Res. 2000, 149:91-105.
44. Frisina R.D., Smith R.L., Chamberlain S.C. Encoding of amplitude modulation in the gerbil cochlear nucleus. I. A hierarchy of enhancement. Hear.Res. 1990, 44:99-122.
45. Fujino K., Oertel D. Cholinergic modulation of stellate cells in the mammalian ventral cochlear nucleus. J. Neurosci. 2001, 21:7372-7383.
46. Fujino K., Koyano K., Ohmori H. Lateral and medial olivocochlear neurons have distinct electrophysiological properties in the rat brain slice. J. Neurophysiol. 1997, 77:2788-2804.
47. Fukui I., Ohmori H. Developmental changes in membrane excitability and morphology of neurons in the nucleus angularis of the chicken. J. Physiol. 2003, 548:219-232.
48. Fukui I., Ohmori H. Tonotopic gradients of membrane and synaptic properties for neurons of the chicken nucleus magnocellularis. J. Neurosci. 2004, 24:7514-7523.
49. Gan L., Perney T.M., Kaczmarek L.K. Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons. J. Biol. Chem. 1996, 271:5859-5865.
50. Garcia-Diaz J.F. Development of a fast transient potassium current in chick cochlear ganglion neurons. Hear. Res. 1999, 135:124.
51. Gittelman J.X., Tempel B.L. Kv1.1-containing channels are critical for temporal precision during spike initiation. J. Neurophysiol. 2006, 96:1203-1214.
52. Godfrey D.A., Kiang N.Y., Norris B.E. Single unit activity in the dorsal cochlear nucleus of the cat. J. Comp. Neurol. 1975, 162:269-284.
53. Golding N.L., Ferragamo M.J., Oertel D. Role of intrinsic conductances underlying responses to transients in octopus cells of the cochlear nucleus. J. Neurosci. 1999, 19:2897-2905.
54. Grigg J.J., Brew H.M., Tempel B.L. Differential expression of voltage-gated potassium channel genes in auditory nuclei of the mouse brainstem. Hear. Res. 2000, 140:77-90.
55. Grothe B., Sanes D.H. Synaptic inhibition influences the temporal coding properties of medial superior olivary neurons: an in vitro study. J. Neurosci. 1994, 14:1701-1709.
56. Guo W., Li H., Aimond F., Johns D.C., Rhodes K.J., Trimmer J.S., Nerbonne J.M. Role of heteromultimers in the generation of myocardial transient outward K+ currents. Circ. Res. 2002, 90:586-593.
57. Hallows J.L., Tempel B.L. Expression of Kv1.1, a Shaker-like potassium channel, is temporally regulated in embryonic neurons and glia. J. Neurosci. 1998, 18:5682-5691.
58. Hefti B.J., Smith P.H. Distribution and kinetic properties of GABAergic inputs to layer V pyramidal cells in rat auditory cortex. J. Assoc. Res. Otolaryngol. 2003, 4:106-121.
59. von Hehn C.A., Bhattacharjee A., Kaczmarek L.K. Loss of Kv3.1 tonotopicity and alterations in cAMP response element-binding protein signaling in central auditory neurons of hearing impaired mice. J. Neurosci. 2004, 24:1936-1940.
60. Heusser K., Schwappach B. Trafficking of potassium channels. Curr. Opin. Neurobiol. 2005, 15:364-369.
61. Holt A.G., Asako M., Keith Duncan R., Lomax C.A., Juiz J.M., Altschuler R.A. Deafness associated changes in expression of two-pore domain potassium channels in the rat cochlear nucleus. Hear. Res. 2006, 216-217:146-153.
62. Hopkins W.F. Toxin and subunit specificity of blocking affinity of three peptide toxins for heteromultimeric, voltage-gated potassium channels expressed in Xenopus oocytes. J. Pharmacol. Exp. Ther. 1998, 285:1051-1060.
63. + channels of the Shab subfamily. J. Neurosci. 1993, 13:1569-1576.
64. Jang G.M., Leong L.E., Hoang L.T., Wang P.H., Gutman G.A., Semler B.L. Structurally distinct elements mediate internal ribosome entry within the 5′-noncoding region of a voltage-gated potassium channel mRNA. J. Biol. Chem. 2004, 279:47419-47430.
65. Jeffress L.A. A place theory of sound localization. J. Comp. Physiol. Pyschol. 1948, 41:35-39.
66. Joris P.X., Carney L.H., Smith P.H., Yin T.C. Enhancement of neural synchronization in the anteroventral cochlear nucleus. I. Responses to tones at the characteristic frequency. J. Neurophysiol. 1994, 71:1022-1036.
67. Kalman K., Nguyen A., Tseng-Crank J., Dukes I.D., Chandy G., Hustad C.M., Copeland N.G., Jenkins N.A., Mohrenweiser H., Brandriff B., Cahalan M., Gutman G.A., Chandy K.G. Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian shaker-related voltage-gated potassium channel, Kv1.7. J. Biol. Chem. 1998, 273:5851-5857.
68. Kanold P.O., Manis P.B. Transient potassium currents regulate the discharge patterns of dorsal cochlear nucleus pyramidal cells. J. Neurosci. 1999, 19:2195-2208.
69. Kanold P.O., Manis P.B. Encoding the timing of inhibition. J. Neurophysiol. 2005, 93:2887-2897.
70. Karschin C., Wischmeyer E., Preisig-Muller R., Rajan S., Derst C., Grzeschik K.H., Daut J., Karschin A. Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system. Mol. Cell. Neurosci. 2001, 18:632-648.
71. + channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:4333-4338.
72. Kim D.O., Sirianni J.G., Chang S.O. Responses of DCN-PVCN neurons and auditory nerve fibers in unanesthetized decerebrate cats to AM and pures tones: analysis with autocorrelation/power-spectrum. Hear. Res. 1990, 45:95-113.
73. + channels during synaptically driven action potentials in the MNTB. J. Neurophysiol. 2006, 96:1547-1555.
74. Koch U., Braun M., Kapfer C., Grothe B. Distribution of HCN1 and HCN2 in rat auditory brainstem nuclei. Eur. J. Neurosci. 2004, 20:79-91.
75. Koppl C. Phase locking to high frequencies in the auditory nerve and cochlear nucleus magnocellularis of the barn owl, Tyto alba. J. Neurosci. 1997, 17:3312-3321.
76. Kopp-Scheinpflug C., Dehmel S., Dorrscheidt G.J., Rubsamen R. Interaction of excitation and inhibition in anteroventral cochlear nucleus neurons that receive large endbulb synaptic endings. J. Neurosci. 2002, 22:11004-11018.
77. Kopp-Scheinpflug C., Lippe W.R., Dorrscheidt G.J., Rubsamen R. The medial nucleus of the trapezoid body in the gerbil is more than a relay: comparison of pre- and postsynaptic activity. J. Assoc. Res. Otolaryngol. 2003, 4:1-23.
78. Kossl M., Vater M. Noradrenaline enhances temporal auditory contrast and neuronal timing precision in the cochlear nucleus of the mustache bat. J. Neurosci. 1989, 9:4169-4179.
79. Kuba H., Koyano K., Ohmori H. Development of membrane conductance improves coincidence detection in the nucleus laminaris of the chicken. J. Physiol. 2002, 540:529-542.
80. Kuba H., Yamada R., Fukui I., Ohmori H. Tonotopic specialization of auditory coincidence detection in nucleus laminaris of the chick. J. Neurosci. 2005, 25:1924-1934.
81. Li R.Y.-S., Guinan J.J. Antidromic and orthodromic stimulation of neurons receiving calyces of Held. MIT Q. Progr. Rep. No 1966, 100:227-234.
82. Li W., Kaczmarek L.K., Perney T.M. Localization of two high-threshold potassium channel subunits in the rat central auditory system. J. Comp. Neurol. 2001, 437:196-218.
83. Liss B., Franz O., Sewing S., Bruns R., Neuhoff H., Roeper J. Tuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcription. EMBO J. 2001, 20:5715-5724.
84. Liu S.J., Kaczmarek L.K. The expression of two splice variants of the Kv3.1 potassium channel gene is regulated by different signaling pathways. J. Neurosci. 1998, 18:2881-2890.
85. Liu S.Q., Kaczmarek L.K. Depolarization selectively increases the expression of the Kv3.1 potassium channel in developing inferior colliculus neurons. J. Neurosci. 1998, 18:8758-8769.
86. Louage D.H., van der Heijden M., Joris P.X. Temporal properties of responses to broadband noise in the auditory nerve. J. Neurophysiol. 2004, 91:2051-2065.
87. Louage D.H., van der Heijden M., Joris P.X. Enhanced temporal response properties of anteroventral cochlear nucleus neurons to broadband noise. J. Neurosci. 2005, 25:1560-1570.
88. Lu Y., Monsivais P., Tempel B.L., Rubel E.W. Activity-dependent regulation of the potassium channel subunits Kv1.1 and Kv3.1. J. Comp. Neurol. 2004, 470:93-106.
89. + channel diversity in the mammalian central nervous system. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:3932-3936.
90. Mainen Z.F., Sejnowski T.J. Influence of dendritic structure on firing pattern in model neocortical neurons. Nature 1996, 382:363-366.
91. Manis P.B. Membrane properties and discharge characteristics of guinea pig dorsal cochlear nucleus neurons studied in vitro. J. Neurosci. 1990, 10:2338-2351.
92. Manis P., Marx S. Outward currents in isolated ventral cochlear nucleus neurons. J. Neurosci. 1991, 11:2865-2880.
93. Manis P., Marx S., White J. Integrative Mechanisms of Ventral Cochlear Nucleus Stellate Cells: Membrane Conductances and Electrotonic Structure. Cochlear Nucleus: Structure and Function in Relation to Modeling 1996, 3:213-229. JAI Press. W.A. Ainsworth, E.F. Evans, C.M. Hackney (Eds.).
94. Manis, P., Mitchell, K., Bortone, D. 2002 Developmental pattern of potassium channel expression in rat cochlear nucleus. Association for Research in Otolaryngology, Midwinter Meeting, St. Petersburg, FL .
95. Manis P.B., Molitor S.C., Wu H. Subthreshold oscillations generated by TTX-sensitive sodium currents in dorsal cochlear nucleus pyramidal cells. Exp. Brain Res. 2003, 153:443-451.
96. Manis P.B., Spirou G.A., Wright D.D., Paydar S., Ryugo D.K. Physiology and morphology of complex spiking neurons in the guinea pig dorsal cochlear nucleus. J. Comp. Neurol. 1994, 348:261-276.
97. McFeeters R.L., Oswald R.E. Emerging structural explanations of ionotropic glutamate receptor function. FASEB J. 2004, 18:428-438.
98. McGinley M.J., Oertel D. Rate thresholds determine the precision of temporal integration in principal cells of the ventral cochlear nucleus. Hear. Res. 2006, 216-217:52-63.
99. Metherate R., Aramakis V. Intrinsic electrophysiology of neurons in thalamarecipient layers of developing rat auditory cortex. Brain Res. Dev. Brain Res. 1999, 115:131-144.
100. Mo Z.L., Adamson C.L., Davis R.L. Dendrotoxin-sensitive K(+) currents contribute to accommodation in murine spiral ganglion neurons. J. Physiol. 2002, 542:763-778.
101. + channels-molecular sensors. Biochim. Biophys. Acta 2002, 1566:152-161.
102. Oertel D. Synaptic responses and electrical properties of cells in brain slices of the mouse anteroventral cochlear nucleus. J. Neurosci. 1983, 3:2043-2053.
103. Oertel D. The role of timing in the brain stem auditory nuclei of vertebrates. Annu. Rev. Physiol. 1999, 61:497-519.
104. + channel alpha-subunit, Kv4.3 in the rat. FEBS Lett. 1997, 420:47-53.
105. + channel subunits expressed by the bushy cells of the rat cochlear nucleus. Hear. Res. 2005, 199:57-70.
106. + currents of the bushy neurones of the rat cochlear nucleus in a thin brain slice preparation. Acta. Physiol. Hung. 2004, 91:83-98.
107. Paolini A.G., FitzGerald J.V., Burkitt A.N., Clark G.M. Temporal processing from the auditory nerve to the medial nucleus of the trapezoid body in the rat. Hear. Res. 2001, 159:101-116.
108. Parameshwaran S., Carr C.E., Perney T.M. Expression of the Kv3.1 potassium channel in the avian auditory brainstem. J. Neurosci. 2001, 21:485-494.
109. Perney T.M., Kaczmarek L.K. Localization of a high threshold potassium channel in the rat cochlear nucleus. J. Comp. Neurol. 1997, 386:178-202.
110. Perney T.M., Marshall J., Martin K.A., Hockfield S., Kaczmarek L.K. Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain. J. Neurophysiol. 1992, 68:756-766.
111. Peruzzi D., Sivaramakrishnan S., Oliver D. Identification of cell types in brain slices of the inferior colliculus. Neuroscience 2000, 101:403-416.
112. Rasband M.N. It's "juxta" potassium channel!. J. Neurosci. Res. 2004, 76:749-757.
113. Rasband M.N., Trimmer J.S. Developmental clustering of ion channels at and near the node of Ranvier. Dev. Biol. 2001, 236:5-16.
114. Rathouz M., Trussell L. Characterization of outward currents in neurons of the avian nucleus magnocellularis. J. Neurophysiol. 1998, 80:2824-2835.
115. Reyes A.D., Rubel E.W., Spain W.J. Membrane properties underlying the firing of neurons in the avian cochlear nucleus. J. Neurosci. 1994, 14:5352-5364.
116. Reyes A.D., Rubel E.W., Spain W.J. In vitro analysis of optimal stimuli for phase-locking and time-delayed modulation of firing in avian nucleus laminaris neurons. J. Neurosci. 1996, 16:993-1007.
117. Rhode W.S., Kettner R.E. Physiological study of neurons in the dorsal and posteroventral cochlear nucleus of the unanesthetized cat. J. Neurophysiol. 1987, 57:414-442.
118. Rhode W.S., Smith P.H. Encoding timing and intensity in the ventral cochlear nucleus of the cat. J. Neurophysiol. 1986, 56:261-286.
119. Rhode W.S., Smith P.H., Oertel D. Physiological response properties of cells labeled intracellularly with horseradish peroxidase in cat dorsal cochlear nucleus. J. Comp. Neurol. 1983, 213:426-447.
120. Richardson F.C., Kaczmarek L.K. Modification of delayed rectifier potassium currents by the Kv9.1 potassium channel subunit. Hear. Res. 2000, 147:21.
121. + channels mediates dendritic targeting. Nat. Neurosci. 2003, 6:243-250.
122. Robbins J. KCNQ potassium channels: physiology, pathophysiology, and pharmacology. Pharmacol. Ther. 2001, 90:1-19.
123. Robinson R.B., Siegelbaum S.A. Hyperpolarization-activated cation currents: from molecules to physiological function. Annu. Rev. Physiol. 2003, 65:453-480.
124. Rodrigues A.R., Oertel D. Hyperpolarization-activated currents regulate excitability in stellate cells of the mammalian ventral cochlear nucleus. J. Neurophysiol. 2006, 95:76-87.
125. Rosenberger M.H., Fremouw T., Casseday J.H., Covey E. Expression of the Kv1.1 ion channel subunit in the auditory brainstem of the big brown bat, Eptesicus fuscus. J. Comp. Neurol. 2003, 462:101-120.
126. Rothman J.S., Manis P.B. Kinetic analyses of three distinct potassium conductances in ventral cochlear nucleus neurons. J. Neurophysiol. 2003, 89:3083-3096.
127. Rothman J.S., Manis P.B. The roles potassium currents play in regulating the electrical activity of ventral cochlear nucleus neurons. J. Neurophysiol. 2003, 89:3097-3113.
128. Rothman J.S., Manis P.B. Differential expression of three distinct potassium currents in the ventral cochlear nucleus. J. Neurophysiol. 2003, 89:3070-3082.
129. Rothman J., Young E. Enhancement of neural synchronization in computational models of ventral cochlear nucleus bushy cells. Aud. Neurosci. 1996, 2:47-62.
130. Rusznak Z., Forsythe I.D., Stanfield P.R. Characterization of the hyperpolarization activated nonspecific cation current (Ih) of bushy neurones from the rat anteroventral cochlear nucleus studied in a thin brain slice preparation. Neurobiology (Bp) 1996, 4:275-276.
131. Sah P., Faber E.S. Channels underlying neuronal calcium-activated potassium currents. Prog. Neurobiol. 2002, 66:345-353.
132. Santos-Sacchi J. Voltage-dependent ionic conductances of type I spiral ganglion cells from the guinea pig inner ear. J. Neurosci. 1993, 13:3599-3611.
133. Schwarz D.W., Puil E. Firing properties of spherical bushy cells in the anteroventral cochlear nucleus of the gerbil. Hear. Res. 1997, 114:127-138.
134. + channels in excitable cells. J. Cell. Mol. Med. 2004, 8:22-30.
135. Scott L.L., Mathews P.J., Golding N.L. Posthearing developmental refinement of temporal processing in principal neurons of the medial superior olive. J. Neurosci. 2005, 25:7887-7895.
136. + channel subunits mediating subthreshold transient K+ (A-type) currents in rat brain. J. Neurophysiol. 1998, 79:1081-1091.
137. + channel proteins in rat central neurons. Neuron 1992, 9:271-284.
138. + channel subunit in different neurons of rat brain. J. Neurosci. 1994, 14:2408-2417.
139. Sheppard D.N., Valverde M.A., Represa J., Giraldez F. Transient outward currents in cochlear ganglion neurons of the chick embryo. Neuroscience 1992, 51:631-639.
140. + channels expressed in transfected mammalian cells. J. Biol. Chem. 1994, 269:23204-23211.
141. Sivaramakrishnan S., Oliver D. Distinct K currents result in physiologically distinct cell types in the inferior colliculus of the rat. J. Neurosci. 2001, 21:2861-2877.
142. Slee S.J., Higgs M.H., Fairhall A.L., Spain W.J. Two-dimensional time coding in the auditory brainstem. J. Neurosci. 2005, 25:9978-9988.
143. Smith P.H. Structural and functional differences distinguish principal from nonprincipal cells in the guinea pig MSO slice. J. Neurophysiol. 1995, 73:1653-1667.
144. Smith P.H., Populin L.C. Fundamental differences between the thalamocortical recipient layers of the cat auditory and visual cortices. J. Comp. Neurol. 2001, 436:508-519.
145. Sonnenburg, R., Bortone, D., Manis, P. 2002. Differential potassium channel gene expression in ventral cochlear nucleus neurons. American Academy of Otolaryngology-Head and Neck Surgery Annual Meeting, San Diego, CA.
146. Spirou G.A., Smith P.H., Manis P.B. Intracellular recording and labeling of neurons in the lateral nucleus of the trapezoid body. Soc. Neurosci. Abstr. 1995, 21:400.
147. + channels: molecular determinants and function of the SK family. Nat. Rev. Neurosci. 2004, 5:758-770.
148. Stuart G., Schiller J., Sakmann B. Action potential initiation and propagation in rat neocortical pyramidal neurons. J. Physiol. 1997, 505(Pt 3):617-632.
149. Sullivan W.E., Konishi M. Segregation of stimulus phase and intensity coding in the cochlear nucleus of the barn owl. J. Neurosci. 1984, 4:1787-1799.
150. Svirskis G. Enhancement of signal-to-noise ratio and phase locking for small inputs by a low-threshold outward current in auditory neurons. J. Neurosci. 2002, 22:11019-11025.
151. Svirskis G., Kotak V., Sanes D.H., Rinzel J. Sodium along with low-threshold potassium currents enhance coincidence detection of subthreshold noisy signals in MSO neurons. J. Neurophysiol. 2004, 91:2465-2473.
152. Thornhill W., Wu M.B., Jiang X., Wu X., Morgan P.T., Margiotta J.F. Expression of Kv1.1 delayed rectifier potassium channels in Lec mutant Chinese hamster ovary cell lines reveals a role for sialidation in channel function. J. Biol. Chem. 1996, 271:19093-19098.
153. Tkatch T., Baranauskas G., Surmeier D.J. Kv4.2 mRNA abundance and A-type K(+) current amplitude are linearly related in basal ganglia and basal forebrain neurons. J. Neurosci. 2000, 20:579-588.
154. Trussell L.O. Synaptic mechanisms for coding timing in auditory neurons. Annu. Rev. Physiol. 1999, 61:477-496.
155. Valverde M.A., Sheppard D.N., Represa J., Giraldez F. Development of Na(+)- and K(+)-currents in the cochlear ganglion of the chick embryo. Neuroscience 1992, 51:621-630.
156. Varga A.W., Yuan L.L., Anderson A.E., Schrader L.A., Wu G.Y., Gatchel J.R., Johnston D., Sweatt J.D. Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents. J. Neurosci. 2004, 24:3643-3654.
157. + currrents by arachidonic acid. J. Neurosci. 1996, 16:2522-2532.
158. Wagner T. Intrinsic properties of identified neurones in the central nucleus of mouse inferior colliculus. NeuroReport 1994, 6:89-93.
159. Wang L.Y., Gan L., Forsythe I.D., Kaczmarek L.K. Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones. J. Physiol. 1998, 509(Pt 1):183-194.
160. + channel subtypes fractioned from rat brain using dendrotoxins. Eur. J. BioChem. 1999, 263:230-237.
161. Wang Y., Manis P.B. Synaptic transmission at the cochlear nucleus endbulb synapse during age-related hearing loss in mice. J Neurophysiol. 2005, 94:1814-1824.
162. Weiser M., Vega-Saenz de Miera E., Kentros C., Moreno H., Franzen L., Hillman D., Baker H., Rudy B. Differential expression of Shaw-related K+ channels in the rat central nervous system. J. Neurosci. 1994, 14:949-972.
163. White J.A., Young E.D., Manis P.B. The electrotonic structure of regular-spiking neurons in the ventral cochlear nucleus may determine their response properties. J. Neurophysiol. 1994, 71:1774-1786.
164. Wo Z.G., Oswald R.E. Unraveling the modular design of glutamate-gated ion channels. Trends Neurosci. 1995, 18:161-168.
165. Wu S.H. Physiological properties of neurons in the ventral nucleus of the lateral lemniscus of the rat: intrinsic membrane properties and synaptic response. J. Neurophysiol. 1999, 81:2862-2874.
166. Wu S.H., Kelly J.B. Physiological properties of neurons in the mouse superior olive: membrane characteristics and postsynaptic responses studied in vitro. J. Neurophysiol. 1991, 65:230-246.
167. Wu S.H., Kelly J.B. In vitro brain slice studies of the rat's dorsal nucleus of the lateral lemniscus. I. Membrane and synaptic response properties. J. Neurophysiol. 1995, 73:780-793.
168. Wu S.H., Oertel D. Intracellular injection with horseradish peroxidase of physiologically characterized stellate and bushy cells in slices of mouse anteroventral cochlear nucleus. J. Neurosci. 1984, 4:1577-1588.
169. Wymore R.S., Negulescu D., Kinoshita K., Kalman K., Aiyar J., Gutman G.A., Chandy K.G. Characterization of the transcription unit of mouse Kv1.4, a voltage-gated potassium channel gene. J. Biol. Chem. 1996, 271:15629-15634.
170. Yamaguchi K., Ohmori H. Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick. J. Physiol. 1990, 420:185-206.
171. + channels in hippocampus involves a mitogen-activated protein kinase pathway. J. Neurosci. 2002, 22:4860-4868.
172. Zhang S., Oertel D. Cartwheel and superficial stellate cells of the dorsal cochlear nucleus of mice: intracellular recordings in slices. J. Neurophysiol. 1993, 69:1384-1397.
173. Zhang S., Trussell L.O. A characterization of excitatory postsynaptic potentials in the avian nucleus magnocellularis. J. Neurophysiol. 1994, 72:705-718.
174. Zheng Q.Y., Johnson K.R., Erway L.C. Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses. Hear. Res. 1999, 130:94-107.
175. Zhou Y., Carney L.H., Colburn H.S. A model for interaural time difference sensitivity in the medial superior olive: interaction of excitatory and inhibitory synaptic inputs, channel dynamics, and cellular morphology. J. Neurosci. 2005, 25:3046-3058.