Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau

Biological Psychiatry

Volumn 74, Issue 5, 2013, Pages 367-374

  Abisambra, Jose ^a   Jinwal, Umesh K ^b   Miyata, Yoshinari ^d   Rogers, Justin ^c   Blair, Laura ^a   Li, Xiaokai ^d   Seguin, Sandlin P ^e   Wang, Li ^a   Jin, Ying ^a   Bacon, Justin ^a   Brady, Sarah ^a   Cockman, Matthew ^a   Guidi, Chantal ^a   Zhang, Juan ^a   Koren, John ^a   Young, Zapporah T ^d   Atkins, Christopher A ^a   Zhang, Bo ^a   Lawson, Lisa Y ^a   Weeber, Edwin J ^c   Brodsky, Jeffrey L ^e   Gestwicki, Jason E ^d   Dickey, Chad A ^a   more..

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Alzheimer's disease; chaperones; Hsc70; rhodacyanine; tau; YM 01

Indexed keywords

CHAPERONE; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; TAU PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BIOCHEMISTRY; BRAIN SLICE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEARNING; MEMORY; MICROTUBULE; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; TAUOPATHY;

EID: 84882250523     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.02.027     Document Type: Article

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