-
1
-
-
77952779305
-
Hsc70 rapidly engages tau after microtubule destabilization
-
Jinwal, U. K., O'Leary, J. C., 3rd, Borysov, S. I., Jones, J. R., Li, Q., Koren, J., 3rd, Abisambra, J. F., Vestal, G. D., Lawson, L. Y., Johnson, A. G., Blair, L. J., Jin, Y., Miyata, Y., Gestwicki, J. E., and Dickey, C. A. (2010) Hsc70 rapidly engages tau after microtubule destabilization. J. Biol. Chem. 285, 16798-16805.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 16798-16805
-
-
Jinwal, U.K.1
O'Leary III, J.C.2
Borysov, S.I.3
Jones, J.R.4
Li, Q.5
Koren III, J.6
Abisambra, J.F.7
Vestal, G.D.8
Lawson, L.Y.9
Johnson, A.G.10
Blair, L.J.11
Jin, Y.12
Miyata, Y.13
Gestwicki, J.E.14
Dickey, C.A.15
-
2
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease
-
Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., and Mandelkow, E. (1998) Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J. Cell Biol. 143, 777-794.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
Mandelkow, E.6
-
3
-
-
0026650367
-
Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons
-
Mattson, M. P. (1992) Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons. Brain Res. 582, 107-118.
-
(1992)
Brain Res.
, vol.582
, pp. 107-118
-
-
Mattson, M.P.1
-
4
-
-
0028143773
-
Distribution of the phosphorylated microtubule-associated protein tau in developing cortical neurons
-
Brion, J. P., Octave, J. N., and Couck, A. M. (1994) Distribution of the phosphorylated microtubule-associated protein tau in developing cortical neurons. Neuroscience 63, 895-909.
-
(1994)
Neuroscience
, vol.63
, pp. 895-909
-
-
Brion, J.P.1
Octave, J.N.2
Couck, A.M.3
-
5
-
-
11144356089
-
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
-
Petrucelli, L., Dickson, D. Kehoe, K., Taylor, J., Snyder, H., Grover, A. De Lucia, M., McGowan, E., Lewis, J., Prihar, G., Kim, J., Dillmann, W. H., Browne, S. E., Hall, A., Voellmy, R., Tsuboi, Y., Dawson, T. M., Wolozin, B., Hardy, J. and Hutton, M. (2004) CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Hum. Mol. Genet. 13, 703-714.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 703-714
-
-
Petrucelli, L.1
Dickson, D.2
Kehoe, K.3
Taylor, J.4
Snyder, H.5
Grover, A.6
De Lucia, M.7
McGowan, E.8
Lewis, J.9
Prihar, G.10
Kim, J.11
Dillmann, W.H.12
Browne, S.E.13
Hall, A.14
Voellmy, R.15
Tsuboi, Y.16
Dawson, T.M.17
Wolozin, B.18
Hardy, J.19
Hutton, M.20
more..
-
6
-
-
33745959291
-
Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species
-
Dickey, C. A., Yue, M., Lin, W. L., Dickson, D. W., Dunmore, J. H., Lee, W. C., Zehr, C., West, G., Cao, S., Clark, A. M., Caldwell, G. A., Caldwell, K. A., Eckman, C., Patterson, C., Hutton, M., and Petrucelli, L. (2006) Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species. J. Neurosci. 26, 6985-6996.
-
(2006)
J. Neurosci.
, vol.26
, pp. 6985-6996
-
-
Dickey, C.A.1
Yue, M.2
Lin, W.L.3
Dickson, D.W.4
Dunmore, J.H.5
Lee, W.C.6
Zehr, C.7
West, G.8
Cao, S.9
Clark, A.M.10
Caldwell, G.A.11
Caldwell, K.A.12
Eckman, C.13
Patterson, C.14
Hutton, M.15
Petrucelli, L.16
-
7
-
-
0037457966
-
Chaperones increase association of tau protein with microtubules
-
Dou, F., Netzer, W. J., Tanemura, K., Li, F., Hartl, F. U., Takashima, A., Gouras, G. K., Greengard, P., and Xu, H. (2003) Chaperones increase association of tau protein with microtubules. Proc. Natl. Acad. Sci. U. S. A. 100, 721-726.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 721-726
-
-
Dou, F.1
Netzer, W.J.2
Tanemura, K.3
Li, F.4
Hartl, F.U.5
Takashima, A.6
Gouras, G.K.7
Greengard, P.8
Xu, H.9
-
8
-
-
84860369416
-
Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance
-
Koren, J., 3rd, Miyata, Y., Kiray, J., O'Leary, J. C., 3rd, Nguyen, L., Guo, J., Blair, L. J., Li, X., Jinwal, U. K., Cheng, J. Q., Gestwicki, J. E., and Dickey, C. A. (2012) Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance. PloS ONE 7, e35566.
-
(2012)
PloS ONE
, vol.7
-
-
Koren III, J.1
Miyata, Y.2
Kiray, J.3
O'Leary III, J.C.4
Nguyen, L.5
Guo, J.6
Blair, L.J.7
Li, X.8
Jinwal, U.K.9
Cheng, J.Q.10
Gestwicki, J.E.11
Dickey, C.A.12
-
9
-
-
33645803596
-
Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels
-
Goldfarb, S. B., Kashlan, O. B., Watkins, J. N., Suaud, L., Yan, W., Kleyman, T. R., and Rubenstein, R. C. (2006) Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels. Proc. Natl. Acad. Sci. U. S. A. 103, 5817-5822.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 5817-5822
-
-
Goldfarb, S.B.1
Kashlan, O.B.2
Watkins, J.N.3
Suaud, L.4
Yan, W.5
Kleyman, T.R.6
Rubenstein, R.C.7
-
10
-
-
0026009921
-
Stable clathrin: Uncoating protein (Hsc70) complexes in intact neurons and their axonal transport
-
Black, M. M., Chestnut, M. H., Pleasure, I. T., and Keen, J. H. (1991) Stable clathrin: uncoating protein (Hsc70) complexes in intact neurons and their axonal transport. J. Neurosci. 11, 1163-1172.
-
(1991)
J. Neurosci.
, vol.11
, pp. 1163-1172
-
-
Black, M.M.1
Chestnut, M.H.2
Pleasure, I.T.3
Keen, J.H.4
-
11
-
-
0025332857
-
Maximal stressinduced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment
-
Williams, G. T., and Morimoto, R. I. (1990) Maximal stressinduced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment. Mol. Cell. Biol. 10, 3125-3136.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 3125-3136
-
-
Williams, G.T.1
Morimoto, R.I.2
-
12
-
-
0030112681
-
A hitchhiker's guide to the human Hsp70 family
-
Tavaria, M., Gabriele, T., Kola, I., and Anderson, R. L. (1996) A hitchhiker's guide to the human Hsp70 family. Cell Stress Chaperones 1, 23-28.
-
(1996)
Cell Stress Chaperones
, vol.1
, pp. 23-28
-
-
Tavaria, M.1
Gabriele, T.2
Kola, I.3
Anderson, R.L.4
-
13
-
-
33645293437
-
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70
-
Qian, S. B., McDonough, H., Boellmann, F., Cyr, D. M., and Patterson, C. (2006) CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70. Nature 440, 551-555.
-
(2006)
Nature
, vol.440
, pp. 551-555
-
-
Qian, S.B.1
McDonough, H.2
Boellmann, F.3
Cyr, D.M.4
Patterson, C.5
-
14
-
-
74949110831
-
The Hsp90 cochaperone, FKBP51, increases tau stability and polymerizes microtubules
-
Jinwal, U. K., Koren, J., 3rd, Borysov, S. I., Schmid, A. B., Abisambra, J. F., Blair, L. J., Johnson, A. G., Jones, J. R., Shults, C. L., O'Leary, J. C., 3rd, Jin, Y., Buchner, J., Cox, M. B., and Dickey, C. A. (2010) The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. J. Neurosci. 30, 591-599.
-
(2010)
J. Neurosci.
, vol.30
, pp. 591-599
-
-
Jinwal, U.K.1
Koren III, J.2
Borysov, S.I.3
Schmid, A.B.4
Abisambra, J.F.5
Blair, L.J.6
Johnson, A.G.7
Jones, J.R.8
Shults, C.L.9
O'Leary III, J.C.10
Jin, Y.11
Buchner, J.12
Cox, M.B.13
Dickey, C.A.14
-
15
-
-
77958566761
-
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
-
O'Leary, J. C., 3rd, Li, Q., Marinec, P., Blair, L. J., Congdon, E. E., Johnson, A. G., Jinwal, U. K., Koren, J., 3rd, Jones, J. R., Kraft, C., Peters, M., Abisambra, J. F., Duff, K. E., Weeber, E. J., Gestwicki, J. E., and Dickey, C. A. (2010) Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden. Mol. Neurodegener. 5, 45.
-
(2010)
Mol. Neurodegener
, vol.5
, pp. 45
-
-
O'Leary III, J.C.1
Li, Q.2
Marinec, P.3
Blair, L.J.4
Congdon, E.E.5
Johnson, A.G.6
Jinwal, U.K.7
Koren III, J.8
Jones, J.R.9
Kraft, C.10
Peters, M.11
Abisambra, J.F.12
Duff, K.E.13
Weeber, E.J.14
Gestwicki, J.E.15
Dickey, C.A.16
-
16
-
-
58249116541
-
Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy
-
Dickey, C., Kraft, C., Jinwal, U., Koren, J., Johnson, A., Anderson, L., Lebson, L., Lee, D., Dickson, D., de Silva, R., Binder, L. I., Morgan, D., and Lewis, J. (2009) Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy. Am. J. Pathol. 174, 228-238.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 228-238
-
-
Dickey, C.1
Kraft, C.2
Jinwal, U.3
Koren, J.4
Johnson, A.5
Anderson, L.6
Lebson, L.7
Lee, D.8
Dickson, D.9
De Silva, R.10
Binder, L.I.11
Morgan, D.12
Lewis, J.13
-
17
-
-
0033534575
-
Kin I kinesins are microtubule-destabilizing enzymes
-
Desai, A., Verma, S., Mitchison, T. J., and Walczak, C. E. (1999) Kin I kinesins are microtubule-destabilizing enzymes. Cell 96, 69-78.
-
(1999)
Cell
, vol.96
, pp. 69-78
-
-
Desai, A.1
Verma, S.2
Mitchison, T.J.3
Walczak, C.E.4
-
18
-
-
29044434835
-
Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts
-
Budde, P. P., Desai, A., and Heald, R. (2006) Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts. Methods 38, 29-34.
-
(2006)
Methods
, vol.38
, pp. 29-34
-
-
Budde, P.P.1
Desai, A.2
Heald, R.3
-
19
-
-
21644446496
-
Sites of tau important for aggregation populate β-structure and bind to microtubules and polyanions
-
Mukrasch, M. D., Biernat, J., von Bergen, M., Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2005) Sites of tau important for aggregation populate β-structure and bind to microtubules and polyanions. J. Biol. Chem. 280, 24978-24986.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 24978-24986
-
-
Mukrasch, M.D.1
Biernat, J.2
Von Bergen, M.3
Griesinger, C.4
Mandelkow, E.5
Zweckstetter, M.6
-
20
-
-
0029400480
-
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
-
Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR 6, 277-293.
-
(1995)
J. Biomol. NMR
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
Bax, A.6
-
21
-
-
19444382397
-
The CCPN data model for NMR spectroscopy: Development of a software pipeline
-
Vranken, W. F., Boucher, W., Stevens, T. J., Fogh, R. H., Pajon, A., Llinas, M., Ulrich, E. L., Markley, J. L., Ionides, J., and Laue, E. D. (2005) The CCPN data model for NMR spectroscopy: development of a software pipeline. Proteins 59, 687-696.
-
(2005)
Proteins
, vol.59
, pp. 687-696
-
-
Vranken, W.F.1
Boucher, W.2
Stevens, T.J.3
Fogh, R.H.4
Pajon, A.5
Llinas, M.6
Ulrich, E.L.7
Markley, J.L.8
Ionides, J.9
Laue, E.D.10
-
22
-
-
78449254717
-
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
-
Abisambra, J. F., Blair, L. J., Hill, S. E., Jones, J. R., Kraft, C., Rogers, J., Koren, J., 3rd, Jinwal, U. K., Lawson, L., Johnson, A. G., Wilcock, D., O'Leary, J. C., Jansen-West, K., Muschol, M., Golde, T. E., Weeber, E. J., Banko, J., and Dickey, C. A. (2010) Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice. J. Neurosci. 30, 15374-15382.
-
(2010)
J. Neurosci.
, vol.30
, pp. 15374-15382
-
-
Abisambra, J.F.1
Blair, L.J.2
Hill, S.E.3
Jones, J.R.4
Kraft, C.5
Rogers, J.6
Koren III, J.7
Jinwal, U.K.8
Lawson, L.9
Johnson, A.G.10
Wilcock, D.11
O'Leary, J.C.12
Jansen-West, K.13
Muschol, M.14
Golde, T.E.15
Weeber, E.J.16
Banko, J.17
Dickey, C.A.18
-
23
-
-
85056045733
-
Development of fluorescence polarization assays for the molecular chaperone Hsp70 family members: Hsp72 and DnaK
-
Ricci, L., and Williams, K. P. (2008) Development of fluorescence polarization assays for the molecular chaperone Hsp70 family members: Hsp72 and DnaK. Curr. Chem. Genomics 2, 90 -95.
-
(2008)
Curr. Chem. Genomics
, vol.2
, pp. 90-95
-
-
Ricci, L.1
Williams, K.P.2
-
24
-
-
19944426695
-
Celastrols as inducers of the heat shock response and cytoprotection
-
Westerheide, S. D., Bosman, J. D., Mbadugha, B. N., Kawahara, T. L., Matsumoto, G., Kim, S., Gu, W., Devlin, J. P., Silverman, R. B., and Morimoto, R. I. (2004) Celastrols as inducers of the heat shock response and cytoprotection. J. Biol. Chem. 279, 56053-56060.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 56053-56060
-
-
Westerheide, S.D.1
Bosman, J.D.2
Mbadugha, B.N.3
Kawahara, T.L.4
Matsumoto, G.5
Kim, S.6
Gu, W.7
Devlin, J.P.8
Silverman, R.B.9
Morimoto, R.I.10
-
25
-
-
77956397168
-
Natural product Celastrol destabilizes tubulin heterodimer and facilitates mitotic cell death triggered by microtubule-targeting anti-cancer drugs
-
Jo, H., Loison, F., Hattori, H., Silberstein, L. E., Yu, H., and Luo, H. R. (2010) Natural product Celastrol destabilizes tubulin heterodimer and facilitates mitotic cell death triggered by microtubule-targeting anti-cancer drugs. PloS ONE 5, e10318.
-
(2010)
PloS ONE
, vol.5
-
-
Jo, H.1
Loison, F.2
Hattori, H.3
Silberstein, L.E.4
Yu, H.5
Luo, H.R.6
-
26
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: The dual role of lysosomal processing
-
Wang, Y., Martinez-Vicente, M., Kruger, U., Kaushik, S., Wong, E., Mandelkow, E. M., Cuervo, A. M., and Mandelkow, E. (2009) Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum. Mol. Genet. 18, 4153-4170.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Kruger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
Cuervo, A.M.7
Mandelkow, E.8
-
27
-
-
57049139853
-
Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone
-
Sarkar, M., Kuret, J., and Lee, G. (2008) Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone. J. Neurosci. Res. 86, 2763-2773.
-
(2008)
J. Neurosci. Res.
, vol.86
, pp. 2763-2773
-
-
Sarkar, M.1
Kuret, J.2
Lee, G.3
-
28
-
-
77954571538
-
A caspase cleaved form of tau is preferentially degraded through the autophagy pathway
-
Dolan, P. J., and Johnson, G. V. (2010) A caspase cleaved form of tau is preferentially degraded through the autophagy pathway. J. Biol. Chem. 285, 21978-21987.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 21978-21987
-
-
Dolan, P.J.1
Johnson, G.V.2
-
29
-
-
0041026092
-
Interaction of Hsp70 chaperones with substrates
-
Rudiger, S., Buchberger, A., and Bukau, B. (1997) Interaction of Hsp70 chaperones with substrates. Nat. Struc. Biol. 4, 342-349.
-
(1997)
Nat. Struc. Biol.
, vol.4
, pp. 342-349
-
-
Rudiger, S.1
Buchberger, A.2
Bukau, B.3
-
30
-
-
0029937037
-
Structural analysis of substrate binding by the molecular chaperone DnaK
-
Zhu, X., Zhao, X., Burkholder, W. F., Gragerov, A., Ogata, C. M., Gottesman, M. E., and Hendrickson, W. A. (1996) Structural analysis of substrate binding by the molecular chaperone DnaK. Science 272, 1606-1614.
-
(1996)
Science
, vol.272
, pp. 1606-1614
-
-
Zhu, X.1
Zhao, X.2
Burkholder, W.F.3
Gragerov, A.4
Ogata, C.M.5
Gottesman, M.E.6
Hendrickson, W.A.7
-
31
-
-
0033013126
-
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
-
Ballinger, C. A., Connell, P., Wu, Y., Hu, Z., Thompson, L. J., Yin, L. Y., and Patterson, C. (1999) Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol. Cell. Biol. 19, 4535-4545.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4535-4545
-
-
Ballinger, C.A.1
Connell, P.2
Wu, Y.3
Hu, Z.4
Thompson, L.J.5
Yin, L.Y.6
Patterson, C.7
-
32
-
-
24144440041
-
In vivo evidence of CHIP up-regulation attenuating tau aggregation
-
Sahara, N., Murayama, M., Mizoroki, T., Urushitani, M., Imai, Y., Takahashi, R., Murata, S., Tanaka, K., and Takashima, A. (2005) In vivo evidence of CHIP up-regulation attenuating tau aggregation. J. Neurochem. 94, 1254-1263.
-
(2005)
J. Neurochem.
, vol.94
, pp. 1254-1263
-
-
Sahara, N.1
Murayama, M.2
Mizoroki, T.3
Urushitani, M.4
Imai, Y.5
Takahashi, R.6
Murata, S.7
Tanaka, K.8
Takashima, A.9
-
33
-
-
0020287643
-
Diverse forms of stress lead to new patterns of gene expression through a common and essential metabolic pathway
-
Hammond, G. L., Lai, Y. K., and Markert, C. L. (1982) Diverse forms of stress lead to new patterns of gene expression through a common and essential metabolic pathway. Proc. Natl. Acad. Sci. U. S. A. 79, 3485-3488.
-
(1982)
Proc. Natl. Acad. Sci. U. S. A.
, vol.79
, pp. 3485-3488
-
-
Hammond, G.L.1
Lai, Y.K.2
Markert, C.L.3
-
34
-
-
0028586833
-
Effects of neurohormonal stress and aging on the activation of mammalian heat shock factor 1
-
Fawcett, T. W., Sylvester, S. L., Sarge, K. D., Morimoto, R. I., and Holbrook, N. J. (1994) Effects of neurohormonal stress and aging on the activation of mammalian heat shock factor 1. J. Biol. Chem. 269, 32272-32278.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32272-32278
-
-
Fawcett, T.W.1
Sylvester, S.L.2
Sarge, K.D.3
Morimoto, R.I.4
Holbrook, N.J.5
-
35
-
-
0027154719
-
Expression of heat shock protein 70 is altered by age and diet at the level of transcription
-
Heydari, A. R., Wu, B., Takahashi, R., Strong, R., and Richardson, A. (1993) Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol. Cell. Biol. 13, 2909-2918.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2909-2918
-
-
Heydari, A.R.1
Wu, B.2
Takahashi, R.3
Strong, R.4
Richardson, A.5
-
36
-
-
0034625060
-
Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
-
Von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. (2000) Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure. Proc. Natl. Acad. Sci. U. S. A. 97, 5129-5134.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5129-5134
-
-
Von Bergen, M.1
Friedhoff, P.2
Biernat, J.3
Heberle, J.4
Mandelkow, E.M.5
Mandelkow, E.6
-
37
-
-
0035930625
-
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
-
Von Bergen, M., Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001) Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure. J. Biol. Chem. 276, 48165-48174.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48165-48174
-
-
Von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
Mandelkow, E.7
-
38
-
-
77649240855
-
Identifying the amylome, proteins capable of forming amyloidlike fibrils
-
Goldschmidt, L., Teng, P. K., Riek, R., and Eisenberg, D. (2010) Identifying the amylome, proteins capable of forming amyloidlike fibrils. Proc. Natl. Acad. Sci. U. S. A. 107, 3487-3492.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 3487-3492
-
-
Goldschmidt, L.1
Teng, P.K.2
Riek, R.3
Eisenberg, D.4
-
39
-
-
13844313010
-
Role for Hsp70 chaperone ins cerevisiae prion seed replication
-
Song, Y., Wu, Y. X., Jung, G., Tutar, Y., Eisenberg, E., Greene, L. E., and Masison, D. C. (2005) Role for Hsp70 chaperone in Saccharomyces cerevisiae prion seed replication. Eukaryot. Cell 4, 289-297.
-
(2005)
Eukaryot. Cell
, vol.4
, pp. 289-297
-
-
Song, Y.1
Wu, Y.X.2
Jung, G.3
Tutar, Y.4
Eisenberg, E.5
Greene, L.E.6
Masison, D.C.7
-
40
-
-
33749818217
-
The structural biology of protein aggregation diseases: Fundamental questions and some answers
-
Eisenberg, D., Nelson, R., Sawaya, M. R., Balbirnie, M., Sambashivan, S., Ivanova, M. I., Madsen, A. O., and Riekel, C. (2006) The structural biology of protein aggregation diseases: fundamental questions and some answers. Acc. Chem. Res. 39, 568-575.
-
(2006)
Acc. Chem. Res.
, vol.39
, pp. 568-575
-
-
Eisenberg, D.1
Nelson, R.2
Sawaya, M.R.3
Balbirnie, M.4
Sambashivan, S.5
Ivanova, M.I.6
Madsen, A.O.7
Riekel, C.8
-
41
-
-
0029837453
-
A receptor for the selective uptake and degradation of proteins by lysosomes
-
Cuervo, A. M., and Dice, J. F. (1996) A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273, 501-503.
-
(1996)
Science
, vol.273
, pp. 501-503
-
-
Cuervo, A.M.1
Dice, J.F.2
-
42
-
-
33646246733
-
HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites
-
Dickey, C. A., Dunmore, J., Lu, B., Wang, J. W., Lee, W. C., Kamal, A., Burrows, F., Eckman, C., Hutton, M., and Petrucelli, L. (2006) HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites. FASEB J. 20, 753-755.
-
(2006)
FASEB J.
, vol.20
, pp. 753-755
-
-
Dickey, C.A.1
Dunmore, J.2
Lu, B.3
Wang, J.W.4
Lee, W.C.5
Kamal, A.6
Burrows, F.7
Eckman, C.8
Hutton, M.9
Petrucelli, L.10
-
43
-
-
33847369469
-
The high-affinity HSP90- CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
-
Dickey, C. A., Kamal, A., Lundgren, K., Klosak, N., Bailey, R. M., Dunmore, J., Ash, P., Shoraka, S., Zlatkovic, J., Eckman, C. B., Patterson, C., Dickson, D. W., Nahman, N. S., Jr., Hutton, M., Burrows, F., and Petrucelli, L. (2007) The high-affinity HSP90- CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. J. Clin. Invest. 117, 648-658.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 648-658
-
-
Dickey, C.A.1
Kamal, A.2
Lundgren, K.3
Klosak, N.4
Bailey, R.M.5
Dunmore, J.6
Ash, P.7
Shoraka, S.8
Zlatkovic, J.9
Eckman, C.B.10
Patterson, C.11
Dickson, D.W.12
Nahman Jr., N.S.13
Hutton, M.14
Burrows, F.15
Petrucelli, L.16
-
44
-
-
70349617699
-
Chemical manipulation of hsp70 ATPase activity regulates tau stability
-
Jinwal, U. K., Miyata, Y., Koren, J., 3rd, Jones, J. R., Trotter, J. H., Chang, L., O'Leary, J., Morgan, D., Lee, D. C., Shults, C. L., Rousaki, A., Weeber, E. J., Zuiderweg, E. R., Gestwicki, J. E., and Dickey, C. A. (2009) Chemical manipulation of hsp70 ATPase activity regulates tau stability. J. Neurosci. 29, 12079-12088.
-
(2009)
J. Neurosci.
, vol.29
, pp. 12079-12088
-
-
Jinwal, U.K.1
Miyata, Y.2
Koren III, J.3
Jones, J.R.4
Trotter, J.H.5
Chang, L.6
O'Leary, J.7
Morgan, D.8
Lee, D.C.9
Shults, C.L.10
Rousaki, A.11
Weeber, E.J.12
Zuiderweg, E.R.13
Gestwicki, J.E.14
Dickey, C.A.15
-
45
-
-
0030969575
-
MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption
-
Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E. M., and Mandelkow, E. (1997) MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. Cell 89, 297-308.
-
(1997)
Cell
, vol.89
, pp. 297-308
-
-
Drewes, G.1
Ebneth, A.2
Preuss, U.3
Mandelkow, E.M.4
Mandelkow, E.5
-
46
-
-
82455208974
-
Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration
-
Li, X., Kumar, Y., Zempel, H., Mandelkow, E. M., Biernat, J., and Mandelkow, E. (2011) Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration. EMBO J. 30, 4825-4837.
-
(2011)
EMBO J.
, vol.30
, pp. 4825-4837
-
-
Li, X.1
Kumar, Y.2
Zempel, H.3
Mandelkow, E.M.4
Biernat, J.5
Mandelkow, E.6
|