Animal, In Vitro, and Cell Culture Models to Study the Role of Dietary Fibers in the Gastrointestinal Tract of Humans

Nondigestible Carbohydrates and Digestive Health

Volumn , Issue , 2011, Pages 97-123

  Faber, Trevor A ^a   Fahey, George C ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Animal evaluations of test substrates cost effective method to prescreen efficacy of substrate before human trials; Animal, in vitro and cell culture models dietary fiber role in gastrointestinal tract of humans; Beneficial physiological roles of plant fiber in human diet, presently undisputed; EnteroMix Colon Simulator semicontinuous device of four vessels connected consecutively; Fermentative in vitro systems in vitro systems, simulating entire gastrointestinal tract; Host microbiota substrate interaction key determinant of fermentable ingredient efficacy; Human subjects, gold standard in substrate evaluation; Hydrolytic and fermentative digestion systems; In vitro systems, screening test substrates for hydrolytic and or fermentative digestion capacity and kinetics; Simulated human intestinal microbial ecosystem (SHIME) chemostatic system, evaluating complete digestive process

Indexed keywords

EID: 84882238674     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470958186.ch5     Document Type: Chapter

References (80)

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