An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

Pain

Volumn 154, Issue 9, 2013, Pages 1749-1757

  Deuis, Jennifer R ^a   Zimmermann, Katharina ^b   Romanovsky, Andrej A ^c   Possani, Lourival D ^d   Cabot, Peter J ^a   Lewis, Richard J ^a   Vetter, Irina ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c ST JOSEPH'S HOSPITAL AND MEDICAL CENTER   (United States)

^d INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

Allodynia; Voltage gated sodium channel

Indexed keywords

4 AMINOPYRIDINE; DELAYED RECTIFIER POTASSIUM CHANNEL; OXALIPLATIN; POTASSIUM CHANNEL; SODIUM CHANNEL NAV1.6; TETRODOTOXIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; COLD; CONTROLLED STUDY; IN VITRO STUDY; INHIBITION KINETICS; INJECTION; LICKING; MALE; MECHANICAL STIMULATION; MEMBRANE POTENTIAL; MEMBRANE RESISTANCE; MOLECULAR DYNAMICS; MOUSE; NERVE CELL MEMBRANE; NERVE EXCITABILITY; NEUROPATHIC PAIN; NONHUMAN; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSORY NERVE; SENSORY NERVE CELL;

ALLODYNIA; VOLTAGE-GATED SODIUM CHANNEL;

4-AMINOPYRIDINE; ANALYSIS OF VARIANCE; ANIMALS; ANTINEOPLASTIC AGENTS; COLD TEMPERATURE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HYPERALGESIA; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NAV1.3 VOLTAGE-GATED SODIUM CHANNEL; NAV1.6 VOLTAGE-GATED SODIUM CHANNEL; NAV1.9 VOLTAGE-GATED SODIUM CHANNEL; NEURALGIA; ORGANOPLATINUM COMPOUNDS; POTASSIUM CHANNEL BLOCKERS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPM CATION CHANNELS;

EID: 84881665070     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.05.032     Document Type: Article

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