메뉴 건너뛰기




Volumn 47, Issue 10, 2013, Pages 1432-1437

Decreased levels of d-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia

Author keywords

D Aspartate; D Serine; NMDA receptors; Schizophrenia

Indexed keywords

DEXTRO AMINO ACID; DEXTRO ASPARTIC ACID; GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 84881557265     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2013.06.013     Document Type: Article
Times cited : (82)

References (59)
  • 2
    • 84868146492 scopus 로고    scopus 로고
    • D-Amino acids in brain neurotransmission and synaptic plasticity
    • Billard J.M. d-Amino acids in brain neurotransmission and synaptic plasticity. Amino Acids 2012, 43:1851-1860.
    • (2012) Amino Acids , vol.43 , pp. 1851-1860
    • Billard, J.M.1
  • 3
    • 84866712322 scopus 로고    scopus 로고
    • NMDA receptor and schizophrenia: a brief history
    • Coyle J.T. NMDA receptor and schizophrenia: a brief history. Schizophrenia Bulletin 2012, 38:920-926.
    • (2012) Schizophrenia Bulletin , vol.38 , pp. 920-926
    • Coyle, J.T.1
  • 5
    • 0034077625 scopus 로고    scopus 로고
    • Occurrence of d-aspartic acid and N-methyl-d-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release
    • D'Aniello A., Di Fiore M.M., Fisher G.H., Milone A., Seleni A., et al. Occurrence of d-aspartic acid and N-methyl-d-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release. FASEB Journal 2000, 14:699-714.
    • (2000) FASEB Journal , vol.14 , pp. 699-714
    • D'Aniello, A.1    Di Fiore, M.M.2    Fisher, G.H.3    Milone, A.4    Seleni, A.5
  • 6
    • 0033735457 scopus 로고    scopus 로고
    • The role of d-aspartic acid and N-methyl-d-aspartic acid in the regulation of prolactin release
    • D'Aniello G., Tolino A., D'Aniello A., Errico F., Fisher G.H., Di Fiore M.M. The role of d-aspartic acid and N-methyl-d-aspartic acid in the regulation of prolactin release. Endocrinology 2000, 141:3862-3870.
    • (2000) Endocrinology , vol.141 , pp. 3862-3870
    • D'Aniello, G.1    Tolino, A.2    D'Aniello, A.3    Errico, F.4    Fisher, G.H.5    Di Fiore, M.M.6
  • 9
    • 84859106184 scopus 로고    scopus 로고
    • Targeting glutamate system for novel antipsychotic approaches: relevance for residual psychotic symptoms and treatment resistant schizophrenia
    • de Bartolomeis A., Sarappa C., Magara S., Iasevoli F. Targeting glutamate system for novel antipsychotic approaches: relevance for residual psychotic symptoms and treatment resistant schizophrenia. European Journal of Pharmacology 2012, 682:1-11.
    • (2012) European Journal of Pharmacology , vol.682 , pp. 1-11
    • de Bartolomeis, A.1    Sarappa, C.2    Magara, S.3    Iasevoli, F.4
  • 10
    • 0034843740 scopus 로고    scopus 로고
    • N-methyl-d-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia
    • Dracheva S., Marras S.A., Elhakem S.L., Kramer F.R., Davis K.L., Haroutunian V. N-methyl-d-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. American Journal of Psychiatry 2001, 158:1400-1410.
    • (2001) American Journal of Psychiatry , vol.158 , pp. 1400-1410
    • Dracheva, S.1    Marras, S.A.2    Elhakem, S.L.3    Kramer, F.R.4    Davis, K.L.5    Haroutunian, V.6
  • 11
    • 84868107074 scopus 로고    scopus 로고
    • New insights on the role of free d-aspartate in the mammalian brain
    • Errico F., Napolitano F., Nistico R., Usiello A. New insights on the role of free d-aspartate in the mammalian brain. Amino Acids 2012, 43:1861-1871.
    • (2012) Amino Acids , vol.43 , pp. 1861-1871
    • Errico, F.1    Napolitano, F.2    Nistico, R.3    Usiello, A.4
  • 12
    • 80053625200 scopus 로고    scopus 로고
    • Increased d-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice
    • Errico F., Nistico R., Napolitano F., Mazzola C., Astone D., Pisapia T., et al. Increased d-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice. Neurobiology of Aging 2011, 32:2229-2243.
    • (2011) Neurobiology of Aging , vol.32 , pp. 2229-2243
    • Errico, F.1    Nistico, R.2    Napolitano, F.3    Mazzola, C.4    Astone, D.5    Pisapia, T.6
  • 13
    • 80052624160 scopus 로고    scopus 로고
    • Persistent increase of d-aspartate in d-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay
    • Errico F., Nistico R., Napolitano F., Oliva A.B., Romano R., Barbieri F., et al. Persistent increase of d-aspartate in d-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay. Neurobiology of Aging 2011, 32:2061-2074.
    • (2011) Neurobiology of Aging , vol.32 , pp. 2061-2074
    • Errico, F.1    Nistico, R.2    Napolitano, F.3    Oliva, A.B.4    Romano, R.5    Barbieri, F.6
  • 14
    • 38649143611 scopus 로고    scopus 로고
    • Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility
    • Errico F., Nistico R., Palma G., Federici M., Affuso A., Brilli E., et al. Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility. Molecular and Cellular Neuroscience 2008, 37:236-246.
    • (2008) Molecular and Cellular Neuroscience , vol.37 , pp. 236-246
    • Errico, F.1    Nistico, R.2    Palma, G.3    Federici, M.4    Affuso, A.5    Brilli, E.6
  • 15
    • 33746196730 scopus 로고    scopus 로고
    • Aphysiological mechanism to regulate d-aspartic acid and NMDA levels in mammals revealed by d-aspartate oxidase deficient mice
    • Errico F., Pirro M.T., Affuso A., Spinelli P., De Felice M., D'Aniello A., et al. Aphysiological mechanism to regulate d-aspartic acid and NMDA levels in mammals revealed by d-aspartate oxidase deficient mice. Gene 2006, 374:50-57.
    • (2006) Gene , vol.374 , pp. 50-57
    • Errico, F.1    Pirro, M.T.2    Affuso, A.3    Spinelli, P.4    De Felice, M.5    D'Aniello, A.6
  • 16
    • 55249126223 scopus 로고    scopus 로고
    • D-Aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801
    • Errico F., Rossi S., Napolitano F., Catuogno V., Topo E., Fisone G., et al. d-Aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801. Journal of Neuroscience 2008, 28:10404-10414.
    • (2008) Journal of Neuroscience , vol.28 , pp. 10404-10414
    • Errico, F.1    Rossi, S.2    Napolitano, F.3    Catuogno, V.4    Topo, E.5    Fisone, G.6
  • 17
    • 0007336643 scopus 로고
    • Selective association of N-methyl aspartate and quisqualate types of l-glutamate receptor with brain postsynaptic densities
    • Fagg G.E., Matus A. Selective association of N-methyl aspartate and quisqualate types of l-glutamate receptor with brain postsynaptic densities. Proceedings of the National Academy of Sciences of the United States of America 1984, 81:6876-6880.
    • (1984) Proceedings of the National Academy of Sciences of the United States of America , vol.81 , pp. 6876-6880
    • Fagg, G.E.1    Matus, A.2
  • 19
    • 0029116094 scopus 로고
    • Dose-finding trial of d-cycloserine added to neuroleptics for negative symptoms in schizophrenia
    • Goff D.C., Tsai G., Manoach D.S., Coyle J.T. Dose-finding trial of d-cycloserine added to neuroleptics for negative symptoms in schizophrenia. American Journal of Psychiatry 1995, 152:1213-1215.
    • (1995) American Journal of Psychiatry , vol.152 , pp. 1213-1215
    • Goff, D.C.1    Tsai, G.2    Manoach, D.S.3    Coyle, J.T.4
  • 20
    • 0027267388 scopus 로고
    • Embryonic development and postnatal changes in free d-aspartate and d-serine in the human prefrontal cortex
    • Hashimoto A., Kumashiro S., Nishikawa T., Oka T., Takahashi K., Mito T., et al. Embryonic development and postnatal changes in free d-aspartate and d-serine in the human prefrontal cortex. Journal of Neurochemistry 1993, 61:348-351.
    • (1993) Journal of Neurochemistry , vol.61 , pp. 348-351
    • Hashimoto, A.1    Kumashiro, S.2    Nishikawa, T.3    Oka, T.4    Takahashi, K.5    Mito, T.6
  • 21
    • 0030850891 scopus 로고    scopus 로고
    • Free d-aspartate and d-serine in the mammalian brain and periphery
    • Hashimoto A., Oka T. Free d-aspartate and d-serine in the mammalian brain and periphery. Progress in Neurobiology 1997, 52:325-353.
    • (1997) Progress in Neurobiology , vol.52 , pp. 325-353
    • Hashimoto, A.1    Oka, T.2
  • 22
    • 0029156742 scopus 로고
    • Anatomical distribution and postnatal changes in endogenous free d-aspartate and d-serine in rat brain and periphery
    • Hashimoto A., Oka T., Nishikawa T. Anatomical distribution and postnatal changes in endogenous free d-aspartate and d-serine in rat brain and periphery. European Journal of Neuroscience 1995, 7:1657-1663.
    • (1995) European Journal of Neuroscience , vol.7 , pp. 1657-1663
    • Hashimoto, A.1    Oka, T.2    Nishikawa, T.3
  • 24
    • 0037977113 scopus 로고    scopus 로고
    • Decreased serum levels of d-serine in patients with schizophrenia: evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia
    • Hashimoto K., Fukushima T., Shimizu E., Komatsu N., Watanabe H., Shinoda N., et al. Decreased serum levels of d-serine in patients with schizophrenia: evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia. Archives of General Psychiatry 2003, 60:572-576.
    • (2003) Archives of General Psychiatry , vol.60 , pp. 572-576
    • Hashimoto, K.1    Fukushima, T.2    Shimizu, E.3    Komatsu, N.4    Watanabe, H.5    Shinoda, N.6
  • 25
    • 35848939420 scopus 로고    scopus 로고
    • Increased levels of glutamate in brains from patients with mood disorders
    • Hashimoto K., Sawa A., Iyo M. Increased levels of glutamate in brains from patients with mood disorders. Biological Psychiatry 2007, 62:1310-1316.
    • (2007) Biological Psychiatry , vol.62 , pp. 1310-1316
    • Hashimoto, K.1    Sawa, A.2    Iyo, M.3
  • 26
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of d-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia
    • Heresco-Levy U., Ermilov M., Shimoni J., Shapira B., Silipo G., Javitt D.C. Placebo-controlled trial of d-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. American Journal of Psychiatry 2002, 159:480-482.
    • (2002) American Journal of Psychiatry , vol.159 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3    Shapira, B.4    Silipo, G.5    Javitt, D.C.6
  • 27
    • 15444377601 scopus 로고    scopus 로고
    • D-Serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia
    • Heresco-Levy U., Javitt D.C., Ebstein R., Vass A., Lichtenberg P., Bar G., et al. d-Serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia. Biological Psychiatry 2005, 57:577-585.
    • (2005) Biological Psychiatry , vol.57 , pp. 577-585
    • Heresco-Levy, U.1    Javitt, D.C.2    Ebstein, R.3    Vass, A.4    Lichtenberg, P.5    Bar, G.6
  • 28
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: version III - the final common pathway
    • Howes O.D., Kapur S. The dopamine hypothesis of schizophrenia: version III - the final common pathway. Schizophrenia Bulletin 2009, 35:549-562.
    • (2009) Schizophrenia Bulletin , vol.35 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 29
    • 33644824256 scopus 로고    scopus 로고
    • D-Aspartate regulates melanocortin formation and function: behavioral alterations in d-aspartate oxidase-deficient mice
    • Huang A.S., Beigneux A., Weil Z.M., Kim P.M., Molliver M.E., Blackshaw S., et al. d-Aspartate regulates melanocortin formation and function: behavioral alterations in d-aspartate oxidase-deficient mice. Journal of Neuroscience 2006, 26:2814-2819.
    • (2006) Journal of Neuroscience , vol.26 , pp. 2814-2819
    • Huang, A.S.1    Beigneux, A.2    Weil, Z.M.3    Kim, P.M.4    Molliver, M.E.5    Blackshaw, S.6
  • 31
    • 84866684683 scopus 로고    scopus 로고
    • Twenty-five years of glutamate in schizophrenia: are we there yet?
    • Javitt D.C. Twenty-five years of glutamate in schizophrenia: are we there yet?. Schizophrenia Bulletin 2012, 38:911-913.
    • (2012) Schizophrenia Bulletin , vol.38 , pp. 911-913
    • Javitt, D.C.1
  • 34
    • 0001062020 scopus 로고
    • Metabolism of amino-acids: deamination of amino-acids
    • Krebs H.A. Metabolism of amino-acids: deamination of amino-acids. Biochemical Journal 1935, 29:1620-1644.
    • (1935) Biochemical Journal , vol.29 , pp. 1620-1644
    • Krebs, H.A.1
  • 35
    • 33746526525 scopus 로고    scopus 로고
    • Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia
    • Kristiansen L.V., Beneyto M., Haroutunian V., Meador-Woodruff J.H. Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Molecular Psychiatry 2006, 11:737-747. 705.
    • (2006) Molecular Psychiatry , vol.11 , Issue.737-747 , pp. 705
    • Kristiansen, L.V.1    Beneyto, M.2    Haroutunian, V.3    Meador-Woodruff, J.H.4
  • 37
    • 84856089057 scopus 로고    scopus 로고
    • Contributions of the d-serine pathway to schizophrenia
    • Labrie V., Wong A.H., Roder J.C. Contributions of the d-serine pathway to schizophrenia. Neuropharmacology 2012, 62:1484-1503.
    • (2012) Neuropharmacology , vol.62 , pp. 1484-1503
    • Labrie, V.1    Wong, A.H.2    Roder, J.C.3
  • 40
    • 0035878137 scopus 로고    scopus 로고
    • Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorder
    • Meador-Woodruff J.H., Hogg A.J., Smith R.E. Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorder. Brain Research Bulletin 2001, 55:631-640.
    • (2001) Brain Research Bulletin , vol.55 , pp. 631-640
    • Meador-Woodruff, J.H.1    Hogg, A.J.2    Smith, R.E.3
  • 41
    • 79953683678 scopus 로고    scopus 로고
    • Glycine transporter 1 as a potential therapeutic target for schizophrenia-related symptoms: evidence from genetically modified mouse models and pharmacological inhibition
    • Mohler H., Boison D., Singer P., Feldon J., Pauly-Evers M., Yee B.K. Glycine transporter 1 as a potential therapeutic target for schizophrenia-related symptoms: evidence from genetically modified mouse models and pharmacological inhibition. Biochemical Pharmacology 2011, 81:1065-1077.
    • (2011) Biochemical Pharmacology , vol.81 , pp. 1065-1077
    • Mohler, H.1    Boison, D.2    Singer, P.3    Feldon, J.4    Pauly-Evers, M.5    Yee, B.K.6
  • 42
    • 33645100452 scopus 로고    scopus 로고
    • The role of N-methyl-d-aspartate receptors in neurogenesis
    • Nacher J., McEwen B.S. The role of N-methyl-d-aspartate receptors in neurogenesis. Hippocampus 2006, 16:267-270.
    • (2006) Hippocampus , vol.16 , pp. 267-270
    • Nacher, J.1    McEwen, B.S.2
  • 44
    • 84868118002 scopus 로고    scopus 로고
    • D-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems
    • Ota N., Shi T., Sweedler J.V. d-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems. Amino Acids 2012, 43:1873-1886.
    • (2012) Amino Acids , vol.43 , pp. 1873-1886
    • Ota, N.1    Shi, T.2    Sweedler, J.V.3
  • 45
    • 84864634182 scopus 로고    scopus 로고
    • Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists
    • Papouin T., Ladepeche L., Ruel J., Sacchi S., Labasque M., Hanini M., et al. Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists. Cell 2012, 150:633-646.
    • (2012) Cell , vol.150 , pp. 633-646
    • Papouin, T.1    Ladepeche, L.2    Ruel, J.3    Sacchi, S.4    Labasque, M.5    Hanini, M.6
  • 48
    • 0032511830 scopus 로고    scopus 로고
    • Emergence of d-aspartic acid in the differentiating neurons of the rat central nervous system
    • Sakai K., Homma H., Lee J.A., Fukushima T., Santa T., Tashiro K., et al. Emergence of d-aspartic acid in the differentiating neurons of the rat central nervous system. Brain Research 1998, 808:65-71.
    • (1998) Brain Research , vol.808 , pp. 65-71
    • Sakai, K.1    Homma, H.2    Lee, J.A.3    Fukushima, T.4    Santa, T.5    Tashiro, K.6
  • 49
    • 0037530516 scopus 로고    scopus 로고
    • Schizophrenia: neural mechanisms for novel therapies
    • Sawa A., Snyder S.H. Schizophrenia: neural mechanisms for novel therapies. Molecular Medicine 2003, 9:3-9.
    • (2003) Molecular Medicine , vol.9 , pp. 3-9
    • Sawa, A.1    Snyder, S.H.2
  • 50
    • 0031774346 scopus 로고    scopus 로고
    • Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of neuroleptic-free schizophrenics: evidence on reversible up-regulation by typical neuroleptics
    • Sokolov B.P. Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of neuroleptic-free schizophrenics: evidence on reversible up-regulation by typical neuroleptics. Journal of Neurochemistry 1998, 71:2454-2464.
    • (1998) Journal of Neurochemistry , vol.71 , pp. 2454-2464
    • Sokolov, B.P.1
  • 51
    • 38449120712 scopus 로고    scopus 로고
    • Dysfunctional and compensatory prefrontal cortical systems, genes and the pathogenesis of schizophrenia
    • Tan H.Y., Callicott J.H., Weinberger D.R. Dysfunctional and compensatory prefrontal cortical systems, genes and the pathogenesis of schizophrenia. Cerebral Cortex 2007, 17(Suppl.1):i171-i181.
    • (2007) Cerebral Cortex , vol.17 , Issue.SUPPL.1
    • Tan, H.Y.1    Callicott, J.H.2    Weinberger, D.R.3
  • 52
    • 33750152689 scopus 로고    scopus 로고
    • Significant linkage and association between a functional (GT)n polymorphism in promoter of the N-methyl-d-aspartate receptor subunit gene (GRIN2A) and schizophrenia
    • Tang J., Chen X., Xu X., Wu R., Zhao J., Hu Z., et al. Significant linkage and association between a functional (GT)n polymorphism in promoter of the N-methyl-d-aspartate receptor subunit gene (GRIN2A) and schizophrenia. Neuroscience Letters 2006, 409:80-82.
    • (2006) Neuroscience Letters , vol.409 , pp. 80-82
    • Tang, J.1    Chen, X.2    Xu, X.3    Wu, R.4    Zhao, J.5    Hu, Z.6
  • 53
    • 0032403626 scopus 로고    scopus 로고
    • D-Serine added to antipsychotics for the treatment of schizophrenia
    • Tsai G., Yang P., Chung L.C., Lange N., Coyle J.T. d-Serine added to antipsychotics for the treatment of schizophrenia. Biological Psychiatry 1998, 44:1081-1089.
    • (1998) Biological Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.C.3    Lange, N.4    Coyle, J.T.5
  • 55
    • 77953231677 scopus 로고    scopus 로고
    • Expression of the hippocampal NMDA receptor GluN1 subunit and its splicing isoforms in schizophrenia: postmortem study
    • Vrajova M., Stastny F., Horacek J., Lochman J., Sery O., Pekova S., et al. Expression of the hippocampal NMDA receptor GluN1 subunit and its splicing isoforms in schizophrenia: postmortem study. Neurochemical Research 2010, 35:994-1002.
    • (2010) Neurochemical Research , vol.35 , pp. 994-1002
    • Vrajova, M.1    Stastny, F.2    Horacek, J.3    Lochman, J.4    Sery, O.5    Pekova, S.6
  • 57
    • 0034618848 scopus 로고    scopus 로고
    • D-Aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release
    • Wolosker H., D'Aniello A., Snyder S.H. d-Aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release. Neuroscience 2000, 100:183-189.
    • (2000) Neuroscience , vol.100 , pp. 183-189
    • Wolosker, H.1    D'Aniello, A.2    Snyder, S.H.3
  • 58
    • 84868092353 scopus 로고    scopus 로고
    • D-Amino acids in the brain and mutant rodents lacking d-amino-acid oxidase activity
    • Yamanaka M., Miyoshi Y., Ohide H., Hamase K., Konno R. d-Amino acids in the brain and mutant rodents lacking d-amino-acid oxidase activity. Amino Acids 2012, 43:1811-1821.
    • (2012) Amino Acids , vol.43 , pp. 1811-1821
    • Yamanaka, M.1    Miyoshi, Y.2    Ohide, H.3    Hamase, K.4    Konno, R.5
  • 59
    • 33645329090 scopus 로고    scopus 로고
    • Significant association between the genetic variations in the 5' end of the N-methyl-d-aspartate receptor subunit gene GRIN1 and schizophrenia
    • Zhao X., Li H., Shi Y., Tang R., Chen W., Liu J., et al. Significant association between the genetic variations in the 5' end of the N-methyl-d-aspartate receptor subunit gene GRIN1 and schizophrenia. Biological Psychiatry 2006, 59:747-753.
    • (2006) Biological Psychiatry , vol.59 , pp. 747-753
    • Zhao, X.1    Li, H.2    Shi, Y.3    Tang, R.4    Chen, W.5    Liu, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.