-
1
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
2
-
-
77952896646
-
TGFbeta signalling: a complex web in cancer progression
-
Ikushima H, Miyazono K, (2010) TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer 10: 415-424.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 415-424
-
-
Ikushima, H.1
Miyazono, K.2
-
3
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
-
4
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, et al. (2008) Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One 3: e2888.
-
(2008)
PLoS One
, vol.3
-
-
Morel, A.P.1
Lievre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
-
5
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, et al. (2011) Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. United States: 2011 Elsevier Inc. pp. 926-940.
-
(2011)
Cell. United States: 2011 Elsevier Inc
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
-
6
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H, (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
7
-
-
77951833781
-
Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells
-
Barker N, Clevers H, (2010) Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells. Gastroenterology 138: 1681-1696.
-
(2010)
Gastroenterology
, vol.138
, pp. 1681-1696
-
-
Barker, N.1
Clevers, H.2
-
8
-
-
73049116186
-
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, et al. (2010) Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6: 25-36.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
Huch, M.2
Kujala, P.3
van de Wetering, M.4
Snippert, H.J.5
-
9
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
de Lau W, Barker N, Low TY, Koo BK, Li VS, et al. (2011) Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476: 293-297.
-
(2011)
Nature
, vol.476
, pp. 293-297
-
-
de Lau, W.1
Barker, N.2
Low, T.Y.3
Koo, B.K.4
Li, V.S.5
-
10
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
-
He XC, Zhang J, Tong WG, Tawfik O, Ross J, et al. (2004) BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 36: 1117-1121.
-
(2004)
Nat Genet
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
Tawfik, O.4
Ross, J.5
-
11
-
-
84855419201
-
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
-
VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, et al. (2012) Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells. Development 139: 488-497.
-
(2012)
Development
, vol.139
, pp. 488-497
-
-
VanDussen, K.L.1
Carulli, A.J.2
Keeley, T.M.3
Patel, S.R.4
Puthoff, B.J.5
-
12
-
-
84859196824
-
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
-
Powell AE, Wang Y, Li Y, Poulin EJ, Means AL, et al. (2012) The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 149: 146-158.
-
(2012)
Cell
, vol.149
, pp. 146-158
-
-
Powell, A.E.1
Wang, Y.2
Li, Y.3
Poulin, E.J.4
Means, A.L.5
-
13
-
-
78650977190
-
EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila
-
Jiang H, Grenley MO, Bravo MJ, Blumhagen RZ, Edgar BA, (2011) EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell 8: 84-95.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 84-95
-
-
Jiang, H.1
Grenley, M.O.2
Bravo, M.J.3
Blumhagen, R.Z.4
Edgar, B.A.5
-
14
-
-
58449088387
-
Gastrointestinal stem cells in development and cancer
-
Brabletz S, Schmalhofer O, Brabletz T, (2009) Gastrointestinal stem cells in development and cancer. J Pathol 217: 307-317.
-
(2009)
J Pathol
, vol.217
, pp. 307-317
-
-
Brabletz, S.1
Schmalhofer, O.2
Brabletz, T.3
-
15
-
-
84867097416
-
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
-
van Es JH, Sato T, van de Wetering M, Lyubimova A, Nee AN, et al. (2012) Dll1+ secretory progenitor cells revert to stem cells upon crypt damage. Nat Cell Biol 14: 1099-1104.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1099-1104
-
-
van Es, J.H.1
Sato, T.2
van de Wetering, M.3
Lyubimova, A.4
Nee, A.N.5
-
16
-
-
84864854371
-
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas
-
Schepers AG, Snippert HJ, Stange DE, van den Born M, van Es JH, et al. (2012) Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas. Science 337: 730-735.
-
(2012)
Science
, vol.337
, pp. 730-735
-
-
Schepers, A.G.1
Snippert, H.J.2
Stange, D.E.3
van den Born, M.4
van Es, J.H.5
-
17
-
-
84867917224
-
Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells
-
Kemper K, Prasetyanti PR, De Lau W, Rodermond H, Clevers H, et al. (2012) Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. Stem Cells 30: 2378-2386.
-
(2012)
Stem Cells
, vol.30
, pp. 2378-2386
-
-
Kemper, K.1
Prasetyanti, P.R.2
De Lau, W.3
Rodermond, H.4
Clevers, H.5
-
18
-
-
84866659449
-
Runx3 protects gastric epithelial cells against epithelial-mesenchymal transition-induced cellular plasticity and tumorigenicity
-
Voon DC, Wang H, Koo JK, Nguyen TA, Hor YT, et al. (2012) Runx3 protects gastric epithelial cells against epithelial-mesenchymal transition-induced cellular plasticity and tumorigenicity. Stem Cells 30: 2088-2099.
-
(2012)
Stem Cells
, vol.30
, pp. 2088-2099
-
-
Voon, D.C.1
Wang, H.2
Koo, J.K.3
Nguyen, T.A.4
Hor, Y.T.5
-
19
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
Li QL, Ito K, Sakakura C, Fukamachi H, Inoue K, et al. (2002) Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 109: 113-124.
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
Ito, K.2
Sakakura, C.3
Fukamachi, H.4
Inoue, K.5
-
20
-
-
79953690315
-
Loss of Runx3 Is a Key Event in Inducing Precancerous State of the Stomach
-
Ito K, Chuang LS, Ito T, Chang TL, Fukamachi H, et al. (2011) Loss of Runx3 Is a Key Event in Inducing Precancerous State of the Stomach. Gastroenterology 140: 1536-1546.
-
(2011)
Gastroenterology
, vol.140
, pp. 1536-1546
-
-
Ito, K.1
Chuang, L.S.2
Ito, T.3
Chang, T.L.4
Fukamachi, H.5
-
21
-
-
20844462896
-
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
-
Gur G, Rubin C, Katz M, Amit I, Citri A, et al. (2004) LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO J 23: 3270-3281.
-
(2004)
EMBO J
, vol.23
, pp. 3270-3281
-
-
Gur, G.1
Rubin, C.2
Katz, M.3
Amit, I.4
Citri, A.5
-
22
-
-
53749098061
-
Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression
-
Nishino J, Kim I, Chada K, Morrison SJ, (2008) Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 135: 227-239.
-
(2008)
Cell
, vol.135
, pp. 227-239
-
-
Nishino, J.1
Kim, I.2
Chada, K.3
Morrison, S.J.4
-
23
-
-
36849078711
-
let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, et al. (2007) let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131: 1109-1123.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
-
24
-
-
84876835924
-
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma
-
Snyder EL, Watanabe H, Magendantz M, Hoersch S, Chen TA, et al. (2013) Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Mol Cell 50: 185-199.
-
(2013)
Mol Cell
, vol.50
, pp. 185-199
-
-
Snyder, E.L.1
Watanabe, H.2
Magendantz, M.3
Hoersch, S.4
Chen, T.A.5
-
25
-
-
77249151403
-
Transforming growth factorbeta(1) transactivates EGFR via an H(2)O(2)-dependent mechanism in squamous carcinoma cell line
-
Lee E, Yi JY, Chung E, Son Y, (2010) Transforming growth factorbeta(1) transactivates EGFR via an H(2)O(2)-dependent mechanism in squamous carcinoma cell line. Cancer Lett 290: 43-48.
-
(2010)
Cancer Lett
, vol.290
, pp. 43-48
-
-
Lee, E.1
Yi, J.Y.2
Chung, E.3
Son, Y.4
-
26
-
-
84861762280
-
Mediators of induced pluripotency and their role in cancer cells - current scientific knowledge and future perspectives
-
Bernhardt M, Galach M, Novak D, Utikal J, (2012) Mediators of induced pluripotency and their role in cancer cells- current scientific knowledge and future perspectives. Biotechnol J 7: 810-821.
-
(2012)
Biotechnol J
, vol.7
, pp. 810-821
-
-
Bernhardt, M.1
Galach, M.2
Novak, D.3
Utikal, J.4
-
27
-
-
66149179125
-
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine
-
Knoepfler PS, (2009) Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells 27: 1050-1056.
-
(2009)
Stem Cells
, vol.27
, pp. 1050-1056
-
-
Knoepfler, P.S.1
-
29
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, et al. (2012) EMT and dissemination precede pancreatic tumor formation. Cell 148: 349-361.
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
-
30
-
-
57149133671
-
HMGA2, microRNAs, and stem cell aging
-
Hammond SM, Sharpless NE, (2008) HMGA2, microRNAs, and stem cell aging. Cell 135: 1013-1016.
-
(2008)
Cell
, vol.135
, pp. 1013-1016
-
-
Hammond, S.M.1
Sharpless, N.E.2
-
31
-
-
38849089984
-
The HMGA proteins: a myriad of functions (Review)
-
Cleynen I, Van de Ven WJ, (2008) The HMGA proteins: a myriad of functions (Review). Int J Oncol 32: 289-305.
-
(2008)
Int J Oncol
, vol.32
, pp. 289-305
-
-
Cleynen, I.1
van de Ven, W.J.2
-
32
-
-
0019303558
-
Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction
-
Roberts AB, Lamb LC, Newton DL, Sporn MB, De Larco JE, et al. (1980) Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction. Proc Natl Acad Sci U S A 77: 3494-3498.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 3494-3498
-
-
Roberts, A.B.1
Lamb, L.C.2
Newton, D.L.3
Sporn, M.B.4
De Larco, J.E.5
-
33
-
-
0020465034
-
Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells
-
Anzano MA, Roberts AB, Meyers CA, Komoriya A, Lamb LC, et al. (1982) Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells. Cancer Res 42: 4776-4778.
-
(1982)
Cancer Res
, vol.42
, pp. 4776-4778
-
-
Anzano, M.A.1
Roberts, A.B.2
Meyers, C.A.3
Komoriya, A.4
Lamb, L.C.5
-
34
-
-
0021338856
-
Transforming growth factor-beta controls receptor levels for epidermal growth factor in NRK fibroblasts
-
Assoian RK, Frolik CA, Roberts AB, Miller DM, Sporn MB, (1984) Transforming growth factor-beta controls receptor levels for epidermal growth factor in NRK fibroblasts. Cell 36: 35-41.
-
(1984)
Cell
, vol.36
, pp. 35-41
-
-
Assoian, R.K.1
Frolik, C.A.2
Roberts, A.B.3
Miller, D.M.4
Sporn, M.B.5
-
35
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, et al. (2009) Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457: 608-611.
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
van Es, J.H.3
van de Wetering, M.4
Begthel, H.5
-
36
-
-
0029662049
-
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M, Peli J, Rudaz C, Schwarz H, Beug H, et al. (1996) TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 10: 2462-2477.
-
(1996)
Genes Dev
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
-
37
-
-
84860158588
-
Cross-talk between TGFbeta1 and EGFR signalling pathways induces TM4SF5 expression and epithelial-mesenchymal transition
-
Kang M, Choi S, Jeong SJ, Lee SA, Kwak TK, et al. (2012) Cross-talk between TGFbeta1 and EGFR signalling pathways induces TM4SF5 expression and epithelial-mesenchymal transition. Biochem J 443: 691-700.
-
(2012)
Biochem J
, vol.443
, pp. 691-700
-
-
Kang, M.1
Choi, S.2
Jeong, S.J.3
Lee, S.A.4
Kwak, T.K.5
-
38
-
-
33847025287
-
Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis
-
Caja L, Ortiz C, Bertran E, Murillo MM, Miro-Obradors MJ, et al. (2007) Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis. Cell Signal 19: 683-694.
-
(2007)
Cell Signal
, vol.19
, pp. 683-694
-
-
Caja, L.1
Ortiz, C.2
Bertran, E.3
Murillo, M.M.4
Miro-Obradors, M.J.5
-
39
-
-
70349142665
-
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
-
Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, et al. (2009) Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev 23: 2140-2151.
-
(2009)
Genes Dev
, vol.23
, pp. 2140-2151
-
-
Gibbons, D.L.1
Lin, W.2
Creighton, C.J.3
Rizvi, Z.H.4
Gregory, P.A.5
-
40
-
-
3543001646
-
Runx3-/- gastric epithelial cells differentiate into intestinal type cells
-
Fukamachi H, Ito K, Ito Y, (2004) Runx3-/- gastric epithelial cells differentiate into intestinal type cells. Biochem Biophys Res Commun 321: 58-64.
-
(2004)
Biochem Biophys Res Commun
, vol.321
, pp. 58-64
-
-
Fukamachi, H.1
Ito, K.2
Ito, Y.3
-
41
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G, (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-5121.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
42
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
-
43
-
-
33748198771
-
Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles
-
Edelman E, Porrello A, Guinney J, Balakumaran B, Bild A, et al. (2006) Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles. Bioinformatics 22: e108-116.
-
(2006)
Bioinformatics
, vol.22
-
-
Edelman, E.1
Porrello, A.2
Guinney, J.3
Balakumaran, B.4
Bild, A.5
-
44
-
-
4644335010
-
Dominant negative Ras enhances lactogenic hormone-induced differentiation by blocking activation of the Raf-Mek-Erk signal transduction pathway
-
Cerrito MG, Galbaugh T, Wang W, Chopp T, Salomon D, et al. (2004) Dominant negative Ras enhances lactogenic hormone-induced differentiation by blocking activation of the Raf-Mek-Erk signal transduction pathway. J Cell Physiol 201: 244-258.
-
(2004)
J Cell Physiol
, vol.201
, pp. 244-258
-
-
Cerrito, M.G.1
Galbaugh, T.2
Wang, W.3
Chopp, T.4
Salomon, D.5
-
45
-
-
67650504966
-
TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays
-
England
-
Geback T, Schulz MM, Koumoutsakos P, Detmar M (2009) TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques. England. pp. 265-274.
-
(2009)
Biotechniques
, pp. 265-274
-
-
Geback, T.1
Schulz, M.M.2
Koumoutsakos, P.3
Detmar, M.4
|