Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

Development

Volumn 139, Issue 3, 2012, Pages 488-497

  VanDussen, Kelli L ^a   Carulli, Alexis J ^a   Keeley, Theresa M ^a   Patel, Sanjeevkumar R ^b   Puthoff, Brent J ^c   Magness, Scott T ^c   Tran, Ivy T ^d   Maillard, Ivan ^b,d,e   Siebel, Christian ^f   Kolterud, Åsa ^e   Grosse, Ann S ^e   Gumucio, Deborah L ^e   Ernst, Stephen A ^e   Tsai, Yu Hwai ^g   Dempsey, Peter J ^a,g   Samuelson, Linda C ^a,b  

^a Departments of Molecular and Integrative Physiology   (United States)

^b Departments of Internal Medicine   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e Departments of Cell and Developmental Biology   (United States)

^f GENENTECH INC   (United States)

^g Departments of Pediatrics and Communicable Diseases   (United States)

Author keywords

Atoh1; Gamma secretase inhibitor; Lgr5; Mouse; Olfactomedin 4; Tuft cell

Indexed keywords

BIOLOGICAL MARKER; NOTCH RECEPTOR; OLFACTOMEDIN 4; PROTEIN ATOH1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CELL TYPE; COLUMNAR EPITHELIUM; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE TARGETING; GOBLET CELL; INTESTINE CRYPT; MARKER GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; SECRETORY CELL; SIGNAL TRANSDUCTION; STEM CELL; TRANSCRIPTION INITIATION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GOBLET CELLS; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; INTESTINE, SMALL; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; ORGAN CULTURE TECHNIQUES; PANETH CELLS; PROMOTER REGIONS, GENETIC; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; SIGNAL TRANSDUCTION; STEM CELLS;

MUS;

EID: 84855419201     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.070763     Document Type: Article

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