The G protein Gα11 is essential for hypertrophic signalling in diabetic myocardium

International Journal of Cardiology

Volumn 167, Issue 4, 2013, Pages 1476-1485

  Reuter, Hannes ^a   Seuthe, Katharina ^a   Korkmaz, Yüksel ^b   Grönke, Sabine ^a   Hoyer, Dieter Paul ^a   Rottlaender, Dennis ^a   Zobel, Carsten ^a   Addicks, Klaus ^a   Hoyer, Johanna ^a   Grimminger, Peter ^a   Brabender, Jan ^d   Wilkie, Thomas M ^c   Erdmann, Erland ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d St Antonius Krankenhaus Kon   (Germany)

Author keywords

G protein signalling; G 11 knockout; Myocardial hypertrophy; NF B; Protein kinase C; Type 1 diabetes

Indexed keywords

CALCINEURIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT 11; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA2; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C LAMBDA; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; ECHOCARDIOGRAPHY; FEMALE; HEART VENTRICLE HYPERTROPHY; HYPERGLYCEMIA; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES;

G PROTEIN SIGNALLING; GΑ(11) KNOCKOUT; MYOCARDIAL HYPERTROPHY; NF-ΚB; PROTEIN KINASE C; TYPE 1 DIABETES;

ANIMALS; CARDIOMEGALY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; SIGNAL TRANSDUCTION;

EID: 84881478425     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.04.039     Document Type: Article

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