-
1
-
-
77951115122
-
International network of cancer genome projects
-
International Cancer Genome Consortium. et al.
-
International Cancer Genome Consortium. et al. International network of cancer genome projects. Nature 464, 993-998 (2010).
-
(2010)
Nature
, vol.464
, pp. 993-998
-
-
-
2
-
-
64749094310
-
The cancer genome
-
Stratton, M.R., Campbell, P.J. & Futreal, P.A. The cancer genome. Nature 458, 719-724 (2009).
-
(2009)
Nature
, vol.458
, pp. 719-724
-
-
Stratton, M.R.1
Campbell, P.J.2
Futreal, P.A.3
-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. & Weinberg, R.A. The hallmarks of cancer. Cell 100, 57-70 (2000). (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. & Weinberg, R.A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
1542515338
-
A census of human cancer genes
-
Futreal, P.A. et al. A census of human cancer genes. Nat. Rev. Cancer 4, 177-183 (2004). (Pubitemid 38337497)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.3
, pp. 177-183
-
-
Futreal, P.A.1
Coin, L.2
Marshall, M.3
Down, T.4
Hubbard, T.5
Wooster, R.6
Rahman, N.7
Stratton, M.R.8
-
6
-
-
0037805547
-
RAS oncogenes: The frst 30 years
-
Malumbres, M. & Barbacid, M. RAS oncogenes: the frst 30 years. Nat. Rev. Cancer 3, 459-465 (2003).
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
7
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
DOI 10.1038/nature00766
-
Davies, H. et al. Mutations of the BRAF gene in human cancer. Nature 417, 949-954 (2002). (Pubitemid 34716871)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmleri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.C.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
8
-
-
77955405475
-
Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor
-
McLaren, W. et al. Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor. Bioinformatics 26, 2069-2070 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2069-2070
-
-
McLaren, W.1
-
9
-
-
84862506964
-
118; Iso-2; iso-3
-
118; iso-2; iso-3. Fly 6, 80-92 (2012).
-
(2012)
Fly
, vol.6
, pp. 80-92
-
-
Cingolani, P.1
-
10
-
-
84864486576
-
VARIANT: Command line, web service and web interface for fast and accurate functional characterization of variants found by next-generation sequencing
-
Medina, I. et al. VARIANT: command line, web service and web interface for fast and accurate functional characterization of variants found by next-generation sequencing. Nucleic Acids Res. 40, W54-W58 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Medina, I.1
-
11
-
-
71549143170
-
The ontology of biological sequences
-
Hoehndorf, R., Kelso, J. & Herre, H. The ontology of biological sequences. BMC Bioinformatics 10, 377 (2009).
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 377
-
-
Hoehndorf, R.1
Kelso, J.2
Herre, H.3
-
12
-
-
84865760395
-
GENCODE: The reference human genome annotation for the ENCODE Project
-
Harrow, J. et al. GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res. 22, 1760-1774 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1760-1774
-
-
Harrow, J.1
-
14
-
-
43349105560
-
The UCSC genome browser
-
(eds. Baxevanis, A.D. et al.)
-
Karolchik, D., Hinrichs, A.S. & Kent, W.J. The UCSC Genome Browser. in Current Protocols in Bioinformatics (eds. Baxevanis, A.D. et al.) 1.4 (2012).
-
(2012)
Current Protocols in Bioinformatics
, pp. 14
-
-
Karolchik, D.1
Hinrichs, A.S.2
Kent, W.J.3
-
15
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Dunham, I. et al. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Dunham, I.1
-
16
-
-
0035173378
-
DbSNP: The NCBI database of genetic variation
-
Sherry, S.T. et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 29, 308-311 (2001). (Pubitemid 32054478)
-
(2001)
Nucleic Acids Research
, vol.29
, Issue.1
, pp. 308-311
-
-
Sherry, S.T.1
Ward, M.-H.2
Kholodov, M.3
Baker, J.4
Phan, L.5
Smigielski, E.M.6
Sirotkin, K.7
-
17
-
-
84975795680
-
An integrated map of genetic variation from 1, 092 human genomes
-
1000 Genomes Project Consortium. et al.
-
1000 Genomes Project Consortium. et al. An integrated map of genetic variation from 1, 092 human genomes. Nature 491, 56- 65 (2012).
-
(2012)
Nature
, vol.491
, pp. 56-65
-
-
-
18
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes, S.A. et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 39, D945-D950 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Forbes, S.A.1
-
19
-
-
77953446523
-
The Human Gene Mutation Database: 2008 update
-
Stenson, P.D. et al. The Human Gene Mutation Database: 2008 update. Genome Med. 1, 13 (2009).
-
(2009)
Genome Med.
, vol.1
, pp. 13
-
-
Stenson, P.D.1
-
20
-
-
58149189856
-
McKusick's Online Mendelian Inheritance in Man (OMIM)
-
Amberger, J., Bocchini, CA., Scott, A.F. & Hamosh, A. McKusick's Online Mendelian Inheritance in Man (OMIM). Nucleic Acids Res 37, D793-D796 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Amberger, J.1
Bocchini, C.A.2
Scott, A.F.3
Hamosh, A.4
-
21
-
-
68149165614
-
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
-
Kumar, P., Henikoff, S. & Ng, P.C. Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat. Protoc. 4, 1073-1081 (2009).
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1073-1081
-
-
Kumar, P.1
Henikoff, S.2
Ng, P.C.3
-
22
-
-
0043122919
-
SIFT: Predicting amino acid changes that affect protein function
-
DOI 10.1093/nar/gkg509
-
Ng, P.C. & Henikoff, S. SIFT: predicting amino acid changes that affect protein function. Nucleic Acids Res. 31, 3812-3814 (2003). (Pubitemid 37442253)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.13
, pp. 3812-3814
-
-
Ng, P.C.1
Henikoff, S.2
-
23
-
-
79953715693
-
Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, condel
-
González-Pérez, A. & López-Bigas, N. Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, condel. Am. J. Hum. Genet. 88, 440-449 (2011).
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 440-449
-
-
González-Pérez, A.1
López-Bigas, N.2
-
24
-
-
80053189298
-
Predicting the functional impact of protein mutations: Application to cancer genomics
-
Reva, B., Antipin, Y. & Sander, C. Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Res. 39, e118 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Reva, B.1
Antipin, Y.2
Sander, C.3
-
25
-
-
65649143465
-
LS-SNP/PDB: Annotated non-synonymous SNPs mapped to Protein Data Bank structures
-
Ryan, M., Diekhans, M., Lien, S., Liu, Y. & Karchin, R. LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures. Bioinformatics 25, 1431-1432 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1431-1432
-
-
Ryan, M.1
Diekhans, M.2
Lien, S.3
Liu, Y.4
Karchin, R.5
-
26
-
-
22244437614
-
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
-
DOI 10.1101/gr.3804205
-
Stone, E.A. & Sidow, A. Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity. Genome Res. 15, 978-986 (2005). (Pubitemid 40994218)
-
(2005)
Genome Research
, vol.15
, Issue.7
, pp. 978-986
-
-
Stone, E.A.1
Sidow, A.2
-
27
-
-
84869873569
-
Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation
-
Gonzalez-Perez, A., Deu-Pons, J. & Lopez-Bigas, N. Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation. Genome Med. 4, 89 (2012).
-
(2012)
Genome Med.
, vol.4
, Issue.89
-
-
Gonzalez-Perez, A.1
Deu-Pons, J.2
Lopez-Bigas, N.3
-
28
-
-
69249115697
-
Cancer-specifc high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations
-
Carter, H. et al. Cancer-specifc high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. Cancer Res. 69, 6660-6667 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 6660-6667
-
-
Carter, H.1
-
29
-
-
34547566118
-
CanPredict: A computational tool for predicting cancer-associated missense mutations
-
Kaminker, J.S., Zhang, Y, Watanabe, C. & Zhang, Z. CanPredict: a computational tool for predicting cancer-associated missense mutations. Nucleic Acids Res. 35, W595-W598 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Kaminker, J.S.1
Zhang, Y.2
Watanabe, C.3
Zhang, Z.4
-
30
-
-
80053297561
-
A new disease-specifc machine learning approach for the prediction of cancer-causing missense variants
-
Capriotti, E. & Altman, R.B. A new disease-specifc machine learning approach for the prediction of cancer-causing missense variants. Genomics 98, 310-317 (2011).
-
(2011)
Genomics
, vol.98
, pp. 310-317
-
-
Capriotti, E.1
Altman, R.B.2
-
31
-
-
79952764520
-
Performance of mutation pathogenicity prediction methods on missense variants
-
Thusberg, J., Olatubosun, A. & Vihinen, M. Performance of mutation pathogenicity prediction methods on missense variants. Hum. Mutat. 32, 358-368 (2011).
-
(2011)
Hum. Mutat.
, vol.32
, pp. 358-368
-
-
Thusberg, J.1
Olatubosun, A.2
Vihinen, M.3
-
32
-
-
79960763462
-
DbNSFP: A lightweight database of human non-synonymous SNPs and their functional predictions
-
Liu, X., Jian, X. & Boerwinkle, E. dbNSFP: a lightweight database of human non-synonymous SNPs and their functional predictions. Hum. Mutat. 32, 894-899 (2011).
-
(2011)
Hum. Mutat.
, vol.32
, pp. 894-899
-
-
Liu, X.1
Jian, X.2
Boerwinkle, E.3
-
33
-
-
84881433937
-
MuPIT Interactive: Webserver for mapping variant positions to annotated, interactive 3D structures
-
in the press)
-
Niknafs, N. et al. MuPIT Interactive: Webserver for mapping variant positions to annotated, interactive 3D structures. Hum. Genet. (in the press).
-
Hum. Genet
-
-
Niknafs, N.1
-
34
-
-
33846467150
-
A systems approach to measuring the binding energy landscapes of transcription factors
-
DOI 10.1126/science.1131007
-
Maerkl, S.J. & Quake, S.R. A systems approach to measuring the binding energy landscapes of transcription factors. Science 315, 233-237 (2007). (Pubitemid 46166367)
-
(2007)
Science
, vol.315
, Issue.5809
, pp. 233-237
-
-
Maerkl, S.J.1
Quake, S.R.2
-
35
-
-
67649982744
-
Diversity and complexity in DNA recognition by transcription factors
-
Badis, G. et al. Diversity and complexity in DNA recognition by transcription factors. Science 324, 1720-1723 (2009).
-
(2009)
Science
, vol.324
, pp. 1720-1723
-
-
Badis, G.1
-
36
-
-
67849122320
-
MEME SUITE: Tools for motif discovery and searching
-
Bailey, T.L. et al. MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res. 37, W202-W208 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Bailey, T.L.1
-
37
-
-
84865712382
-
Annotation of functional variation in personal genomes using RegulomeDB
-
Boyle, A.P. et al. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22, 1790-1797 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1790-1797
-
-
Boyle, A.P.1
-
38
-
-
38549096565
-
JASPAR, the open access database of transcription factor-binding profiles: New content and tools in the 2008 update
-
DOI 10.1093/nar/gkm955
-
Bryne, J.C. et al. JASPAR, the open access database of transcription factor-binding profles: new content and tools in the 2008 update. Nucleic Acids Res. 36, D102-D106 (2008). (Pubitemid 351149704)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.SUPPL. 1
-
-
Bryne, J.C.1
Valen, E.2
Tang, M.-H.E.3
Marstrand, T.4
Winther, O.5
Da Piedade, I.6
Krogh, A.7
Lenhard, B.8
Sandelin, A.9
-
39
-
-
2442694043
-
Large-scale analysis of non-synonymous coding region single nucleotide polymorphisms
-
DOI 10.1093/bioinformatics/bth029
-
Clifford, R.J., Edmonson, M.N., Nguyen, C. & Buetow, K.H. Large-scale analysis of non-synonymous coding region single nucleotide polymorphisms. Bioinformatics 20, 1006-1014 (2004). (Pubitemid 38660336)
-
(2004)
Bioinformatics
, vol.20
, Issue.7
, pp. 1006-1014
-
-
Clifford, R.J.1
Edmonson, M.N.2
Nguyen, C.3
Buetow, K.H.4
-
40
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance, E.D. et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 463, 184-190 (2010).
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
-
41
-
-
77951800353
-
An effective model for natural selection in promoters
-
Hoffman, M.M. & Birney, E. An effective model for natural selection in promoters. Genome Res. 20, 685-692 (2010).
-
(2010)
Genome Res.
, vol.20
, pp. 685-692
-
-
Hoffman, M.M.1
Birney, E.2
-
42
-
-
84868198825
-
Breast cancer risk-associated SNPs modulate the affnity of chromatin for FOXA1 and alter gene expression
-
Cowper-Sal Lari, R. et al. Breast cancer risk-associated SNPs modulate the affnity of chromatin for FOXA1 and alter gene expression. Nat Genet. 44, 1191-1198 (2012).
-
(2012)
Nat Genet.
, vol.44
, pp. 1191-1198
-
-
Cowper-Sal Lari, R.1
-
43
-
-
84555171449
-
Exome sequencing identifes recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
-
Quesada, V. et al. Exome sequencing identifes recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat. Genet. 44, 47-52 (2011).
-
(2011)
Nat. Genet.
, vol.44
, pp. 47-52
-
-
Quesada, V.1
-
44
-
-
84874191269
-
TERT promoter mutations in familial and sporadic melanoma
-
Horn, S. et al. TERT promoter mutations in familial and sporadic melanoma. Science 339, 959-961 (2013).
-
(2013)
Science
, vol.339
, pp. 959-961
-
-
Horn, S.1
-
45
-
-
84874189784
-
Highly recurrent TERT promoter mutations in human melanoma
-
Huang, F.W. et al. Highly recurrent TERT promoter mutations in human melanoma. Science 339, 957-959 (2013).
-
(2013)
Science
, vol.339
, pp. 957-959
-
-
Huang, F.W.1
-
46
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance, E.D. et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463, 191-196 (2010).
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
-
47
-
-
84857942952
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
-
Lohr, J.G. et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc. Natl. Acad. Sci. USA 109, 3879-3884 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 3879-3884
-
-
Lohr, J.G.1
-
48
-
-
63449141981
-
Human mutation rate associated with DNA replication timing
-
Stamatoyannopoulos, J.A. et al. Human mutation rate associated with DNA replication timing. Nat. Genet. 41, 393-395 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 393-395
-
-
Stamatoyannopoulos, J.A.1
-
49
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
DOI 10.1038/nature05610, PII NATURE05610
-
Greenman, C. et al. Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158 (2007). (Pubitemid 46398669)
-
(2007)
Nature
, vol.446
, Issue.7132
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
Edkins, S.11
O'Meara, S.12
Vastrik, I.13
Schmidt, E.E.14
Avis, T.15
Barthorpe, S.16
Bhamra, G.17
Buck, G.18
Choudhury, B.19
Clements, J.20
Cole, J.21
Dicks, E.22
Forbes, S.23
Gray, K.24
Halliday, K.25
Harrison, R.26
Hills, K.27
Hinton, J.28
Jenkinson, A.29
Jones, D.30
Menzies, A.31
Mironenko, T.32
Perry, J.33
Raine, K.34
Richardson, D.35
Shepherd, R.36
Small, A.37
Tofts, C.38
Varian, J.39
Webb, T.40
West, S.41
Widaa, S.42
Yates, A.43
Cahill, D.P.44
Louis, D.N.45
Goldstraw, P.46
Nicholson, A.G.47
Brasseur, F.48
Looijenga, L.49
Weber, B.L.50
Chiew, Y.-E.51
DeFazio, A.52
Greaves, M.F.53
Green, A.R.54
Campbell, P.55
Birney, E.56
Easton, D.F.57
Chenevix-Trench, G.58
Tan, M.-H.59
Khoo, S.K.60
Teh, B.T.61
Yuen, S.T.62
Leung, S.Y.63
Wooster, R.64
Futreal, P.A.65
Stratton, M.R.66
more..
-
50
-
-
84864258996
-
A landscape of driver mutations in melanoma
-
Hodis, E. et al. A landscape of driver mutations in melanoma. Cell 150, 251-263 (2012).
-
(2012)
Cell
, vol.150
, pp. 251-263
-
-
Hodis, E.1
-
51
-
-
84864598664
-
MuSiC: Identifying mutational signifcance in cancer genomes
-
Dees, N.D. et al. MuSiC: identifying mutational signifcance in cancer genomes. Genome Res. 22, 1589-1598 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1589-1598
-
-
Dees, N.D.1
-
52
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
advance online publication doi:10.1038/nature12213 (16 June 2013)
-
Lawrence, M.S. et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature advance online publication, doi:10.1038/nature12213 (16 June 2013).
-
Nature
-
-
Lawrence, M.S.1
-
54
-
-
84873802661
-
Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers
-
Reimand, J. & Bader, G.D. Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers. Mol. Syst. Biol. 9, 637 (2013).
-
(2013)
Mol. Syst. Biol.
, vol.9
, pp. 637
-
-
Reimand, J.1
Bader, G.D.2
-
55
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
DOI 10.1126/science.1133427
-
Sjöblom, T. et al. The consensus coding sequences of human breast and colorectal cancers. Science 314, 268-274 (2006). (Pubitemid 44571966)
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
Szabo, S.11
Buckhaults, P.12
Farrell, C.13
Meeh, P.14
Markowitz, S.D.15
Willis, J.16
Dawson, D.17
Willson, J.K.V.18
Gazdar, A.F.19
Hartigan, J.20
Wu, L.21
Liu, C.22
Parmigiani, G.23
Park, B.H.24
Bachman, K.E.25
Papadopoulos, N.26
Vogelstein, B.27
Kinzler, K.W.28
Velculescu, V.E.29
more..
-
56
-
-
84866122803
-
Navigating cancer network attractors for tumor-specifc therapy
-
Creixell, P., Schoof, E.M., Erler, J.T. & Linding, R. Navigating cancer network attractors for tumor-specifc therapy. Nat. Biotechnol. 30, 842-848 (2012).
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 842-848
-
-
Creixell, P.1
Schoof, E.M.2
Erler, J.T.3
Linding, R.4
-
57
-
-
84874732372
-
CRAVAT: Cancer-related analysis of variants toolit
-
Douville, C. et al. CRAVAT: Cancer-Related Analysis of VAriants Toolit. Bioinformatics 29, 647-648 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 647-648
-
-
Douville, C.1
-
58
-
-
84874741731
-
Identifying Mendelian disease genes with the Variant Effect Scoring Tool
-
Carter, H. et al. Identifying Mendelian disease genes with the Variant Effect Scoring Tool. BMC Genomics 14 (suppl. 3), S3 (2013).
-
(2013)
BMC Genomics
, vol.14
, Issue.SUPPL. 3
-
-
Carter, H.1
-
59
-
-
77449141217
-
IntOGen: Integration and data-mining of multidimensional oncogenomic data
-
Gundem, G. et al. IntOGen: integration and data-mining of multidimensional oncogenomic data. Nat. Methods 7, 92-93 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 92-93
-
-
Gundem, G.1
-
60
-
-
77951640946
-
A method and server for predicting damaging missense mutations
-
Adzhubei, I.A. et al. A method and server for predicting damaging missense mutations. Nat. Methods 7, 248-249 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 248-249
-
-
Adzhubei, I.A.1
-
61
-
-
79959873016
-
Correlation of somatic mutation and expression identifes genes important in human glioblastoma progression and survival
-
Masica, D.L. & Karchin, R. Correlation of somatic mutation and expression identifes genes important in human glioblastoma progression and survival. Cancer Res. 71, 4550-4561 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 4550-4561
-
-
Masica, D.L.1
Karchin, R.2
-
62
-
-
77949537825
-
Bi-directional SIFT predicts a subset of activating mutations
-
Lee, W., Zhang, Y., Mukhyala, K., Lazarus, R.A. & Zhang, Z. Bi-directional SIFT predicts a subset of activating mutations. PLoS ONE 4, e8311 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Lee, W.1
Zhang, Y.2
Mukhyala, K.3
Lazarus, R.A.4
Zhang, Z.5
-
63
-
-
84866436691
-
PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis
-
Ng, S. et al. PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis. Bioinformatics 28, i640-i646 (2012).
-
(2012)
Bioinformatics
, vol.28
-
-
Ng, S.1
-
64
-
-
84867333656
-
Genome sequencing identifes a basis for everolimus sensitivity
-
Iyer, G. et al. Genome sequencing identifes a basis for everolimus sensitivity. Science 338, 221 (2012).
-
(2012)
Science
, vol.338
, pp. 221
-
-
Iyer, G.1
-
65
-
-
84864185889
-
Getting personalized cancer genome analysis into the clinic: The challenges in bioinformatics
-
Valencia, A. & Hidalgo, M. Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics. Genome Med. 4, 61 (2012).
-
(2012)
Genome Med.
, vol.4
, pp. 61
-
-
Valencia, A.1
Hidalgo, M.2
|