Microprecision delivery of oligonucleotides in a 3D tissue model and its characterization using optical imaging

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 2868-2879

  Luo, Zhen ^a   Ye, Ting ^a   Ma, Yunzhe ^b   Gill, Harvinder Singh ^b   Nitin, N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Electrical and Computer Engineering   (United States)

Author keywords

antisense; cholesterol; imaging; microneedle; oligonucleotide delivery; silencing; streptolysin O; tissue

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CHOLESTEROL; CHOLESTEROL OLIGONUCLEOTIDE CONJUGATE; GREEN FLUORESCENT PROTEIN; OLIGONUCLEOTIDE; OLIGONUCLEOTIDE STREPTOLYSIN O CONJUGATE; STREPTOLYSIN O; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; FLUORESCENCE IMAGING; GENE EXPRESSION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; MICRONEEDLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE DISTRIBUTION; TISSUES;

COLLAGEN; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; OLIGONUCLEOTIDES;

EID: 84881361987     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300717f     Document Type: Article

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