Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes

International Journal of Pharmaceutics

Volumn 197, Issue 1-2, 2000, Pages 233-238

  Birchall, James C ^a   Marichal, Claire ^a,b   Campbell, Lee ^a   Alwan, Ashraf ^a   Hadgraft, Jonathan ^a   Gumbleton, Mark ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Cationic liposomes; Epidermis; Ex vivo model; Gene therapy; Skin

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CATIONIC SURFACTANT; NUCLEASE; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DEGRADATION; DRUG DELIVERY SYSTEM; EXPRESSION VECTOR; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; STRATUM CORNEUM;

ADMINISTRATION, TOPICAL; ANIMALS; DNA; DRUG CARRIERS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; LIPOSOMES; MALE; MICE; MICE, INBRED HRS; MICROSCOPY, ELECTRON; PLASMIDS; SKIN; SKIN ABSORPTION;

EID: 0033993424     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00336-7     Document Type: Article

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