Delivery of Intercellular Adhesion Molecule-1 Antisense Oligonucleotides Using a Topical Hydrogel Tissue Sealant in a Murine Partial Nephrectomy/Ischemia Model

Urology

Volumn 72, Issue 3, 2008, Pages 690-695

  Phull, Hardeep ^a   Lien, Yeong Hau H ^a   Salkini, Mohamed W ^a   Escobar, Christina ^a   Lai, Li Wen ^a   Ramakumar, Sanjay ^b  

^a UNIVERSITY OF ARIZONA   (United States)

^b Urological Associates of Southern Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; INTERCELLULAR ADHESION MOLECULE 1; MACROGOL; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTISENSE THERAPY; ARTICLE; CONTROLLED STUDY; GENE DELIVERY SYSTEM; HISTOPATHOLOGY; HYDROGEL; IMMUNOHISTOCHEMISTRY; KIDNEY ISCHEMIA; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PARTIAL NEPHRECTOMY; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SCORING SYSTEM; SURVIVAL RATE; TISSUE INJURY;

ANIMALS; GENE THERAPY; HYDROGELS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; ISCHEMIA; KIDNEY; MALE; MICE; MICE, INBRED C57BL; NEPHRECTOMY; OLIGONUCLEOTIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; WARM ISCHEMIA;

EID: 50249132726     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2007.12.042     Document Type: Article

References (20)

1. Sheridan A.M., and Bonventre J.V. Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephrol Hypertens 9 (2000) 427-434
2. Etzioni A. Adhesion molecules-their role in health and disease. Pediatr Res 39 (1996) 191-198
3. Dragun D., Tulius S.G., Park J.K., et al. ICAM-1 antisense oligodeoxynucleotides prevent reperfusion injury and enhance immediate graft function in renal transplantation. Kidney Int 54 (1998) 590-602
4. Dong V.M., and Tilney N.L. Reduction of ischemia/reperfusion injury in organ transplants by cytoprotective strategies. Curr Opin Org Transplant 6 (2001) 69-74
5. Star R.A. Treatment of acute renal failure. Kidney Int 54 (1998) 1817-1831
6. Kelly K.J., Williams W.W., Colvin R.B., et al. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest 97 (1996) 1056-1063
7. Kausch I., and Bohle A. Antisense oligonucleotide therapy in urology. J Urol 168 (2002) 239-247
8. Chen W., Bennett C.F., Wang M.E., et al. Perfusion of kidneys with unformulated "naked" intercellular adhesion molecule-1 antisense oligodeoxynucleotides prevents ischemic/reperfusion injury. Transplantation 68 (1999) 880-887
9. Stepkowski S.M., Wang M.E., Condon T.P., et al. Protection against allograft rejection with intracellular adhesion molecule-1 antisense oligodeoxynucleotides. Transplantation 66 (1998) 699-707
10. Haller H., Maasch C., Dragun D., et al. Antisense oligodeoxynucleotide strategies in renal and cardiovascular disease. Kidney Int 53 (1998) 1550-1558
11. Patil S.D., Rhodes D.G., and Burgess D.J. DNA-based therapeutics and DNA delivery systems: a comprehensive review. AAPS J 7 (2005) E61-E77
12. Ramakumar S., Phull H., Purves T., et al. Novel delivery of oligonucleotides using a topical hydrogel tissue sealant in a murine partial nephrectomy model. J Urol 174 (2005) 1133-1136
13. Melnikov V.Y., Ecder T., Fantuzzi G., et al. Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. J Clin Invest 107 (2001) 1145-1152
14. Azuma H., Tomita N., Kaneda Y., et al. Transfection of NFkappaB-decoy oligodeoxynucleotides using efficient ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat renal allografts. Gene Ther 10 (2003) 415-425
15. Lee C.T., Shang S., Lai L.W., et al. Effect of thiazide on renal gene expression of apical calcium channels and calbindins. Am J Physiol Renal Physiol 287 (2004) F1164-F1170
16. Azuma H., Nadeau K., Takada M., et al. Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/reperfusion injury of a single kidney. Transplantation 64 (1997) 190-197
17. Kelly K.J., Williams W.W., Colvin R.B., et al. Antibody to intercellular adhesion molecule-1 protects the kidney against ischemic injury. Proc Natl Acad Sci U S A 91 (1994) 812-816
18. DeGreef K.E., Ysebaert D.K., Persy V., et al. ICAM-1 expression and leukocyte accumulation in inner stripe of outer medulla in early phase of ischemic compared to HgCl2-induced ARF. Kidney Int 63 (2003) 1697-1707
19. Okusa M.D., Linden J., Huang L., et al. A2A adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion. Am J Physiol Renal Physiol 279 (2000) F809-F818
20. Olof P., Hellberg A., Kallskog O., et al. Red cell trapping and postischemic renal blood flow. Differences between the cortex, outer and inner medulla. Kidney Int 40 (1991) 625-631