Beneficial effects of (RS)-glucoraphanin on the tight junction dysfunction in a mouse model of restraint stress

Life Sciences

Volumn 93, Issue 7, 2013, Pages 288-305

  Foti Cuzzola, Valeria ^a   Galuppo, Maria ^a   Iori, Renato ^b   De Nicola, Gina Rosalinda ^b   Cassata, Giovanni ^c   Giacoppo, Sabrina ^a   Bramanti, Placido ^a   Mazzon, Emanuela ^a  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^c ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA SICILIA A MIRRI   (Italy)

Author keywords

Blood brain barrier; Claudins; RS glucoraphanin; Restraint stress; Tight junctions; ZO 1

Indexed keywords

3 NITROTYROSINE; CLAUDIN 1; CLAUDIN 3; GLUCORAPHANIN; GLUCOSINOLATE; I KAPPA B ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; PROTEIN ZO1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-NITROTYROSINE; CASPASE 3; CLAUDIN; COLORING AGENT; CYTOKINE; DRUG DERIVATIVE; EVANS BLUE; GA BINDING PROTEIN; GABPA PROTEIN, MOUSE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOSIDASE; IMIDOESTER; THIOGLUCOSIDASE; TRANSCRIPTION FACTOR RELA; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL INDUSTRY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EXTRAVASATION; HISTOPATHOLOGY; HOMEOSTASIS; IMMOBILIZATION STRESS; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TIGHT JUNCTION; ANIMAL; BLOOD BRAIN BARRIER; DRUG EFFECT; ENZYME ACTIVATION; EXERCISE; ISOLATION AND PURIFICATION; MENTAL STRESS; METABOLISM; PATHOLOGY; R(S)-GLUCORAPHANIN; ZO-1;

ANIMALIA; BRASSICACEAE; MUS;

BLOOD-BRAIN BARRIER; CLAUDINS; R(S)-GLUCORAPHANIN; RESTRAINT STRESS; TIGHT JUNCTIONS; ZO-1;

ANIMALS; BLOOD-BRAIN BARRIER; CASPASE 3; CLAUDINS; COLORING AGENTS; CYTOKINES; ENZYME ACTIVATION; EVANS BLUE; GA-BINDING PROTEIN TRANSCRIPTION FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSINOLATES; GLYCOSIDE HYDROLASES; IMIDOESTERS; MICE; NITRIC OXIDE SYNTHASE TYPE II; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL; TIGHT JUNCTIONS; TRANSCRIPTION FACTOR RELA; TYROSINE;

EID: 84881316076     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.07.003     Document Type: Article

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