-
1
-
-
84861120187
-
Role of basic science in the development of new medicines: Examples from the eicosanoid field
-
Samuelsson B (2012) Role of basic science in the development of new medicines: examples from the eicosanoid field. J Biol Chem 287:10070-10080.
-
(2012)
J Biol Chem
, vol.287
, pp. 10070-10080
-
-
Samuelsson, B.1
-
2
-
-
33846473252
-
Cytochrome P450 systems-biological variations of electron transport chains
-
Hannemann F, Bichet A, Ewen KM, Bernhardt R (2007) Cytochrome P450 systems-biological variations of electron transport chains. Biochim Biophys Acta 1770:330-344.
-
(2007)
Biochim Biophys Acta
, vol.1770
, pp. 330-344
-
-
Hannemann, F.1
Bichet, A.2
Ewen, K.M.3
Bernhardt, R.4
-
3
-
-
33744520321
-
Cytochromes P450 as versatile biocatalysts
-
Bernhardt R (2006) Cytochromes P450 as versatile biocatalysts. J Biotechnol 124:128-145.
-
(2006)
J Biotechnol
, vol.124
, pp. 128-145
-
-
Bernhardt, R.1
-
4
-
-
34047173527
-
Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues
-
Delozier TC, Kissling GE, Coulter SJ, Dai D, Foley JF, Bradbury JA, Murphy E, Steenbergen C, Zeldin DC, Goldstein J (2007) Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues. Drug Metab Dispos 35:682-688.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 682-688
-
-
Delozier, T.C.1
Kissling, G.E.2
Coulter, S.J.3
Dai, D.4
Foley, J.F.5
Bradbury, J.A.6
Murphy, E.7
Steenbergen, C.8
Zeldin, D.C.9
Goldstein, J.10
-
6
-
-
32044443160
-
CYP2J27 single nucleotide polymorphism in a Chinese population
-
Wang H, Jiang Y, Liu Y, Lin C, Cheng G, Chen X, Hao B, Tan W, Lin D, He F (2006) CYP2J27 single nucleotide polymorphism in a Chinese population. Clin Chim Acta 365:125-128.
-
(2006)
Clin Chim Acta
, vol.365
, pp. 125-128
-
-
Wang, H.1
Jiang, Y.2
Liu, Y.3
Lin, C.4
Cheng, G.5
Chen, X.6
Hao, B.7
Tan, W.8
Lin, D.9
He, F.10
-
7
-
-
77956252084
-
Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide
-
Xiao B, Li X, Yan J, Yu X, Yang G, Xiao X, Voltz JW, Zeldin DC, Wang DW (2010) Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide. J Pharmacol Exp Ther 334:784-794.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 784-794
-
-
Xiao, B.1
Li, X.2
Yan, J.3
Yu, X.4
Yang, G.5
Xiao, X.6
Voltz, J.W.7
Zeldin, D.C.8
Wang, D.W.9
-
8
-
-
84856747668
-
Epoxides and soluble epoxide hydrolase in cardiovascular physiology
-
Imig JD (2012) Epoxides and soluble epoxide hydrolase in cardiovascular physiology. Physiol Rev 92:101-130.
-
(2012)
Physiol Rev
, vol.92
, pp. 101-130
-
-
Imig, J.D.1
-
9
-
-
70349636047
-
Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases
-
Imig JD, Hammock BD (2009) Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat Rev Drug Discov 8:794-805.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 794-805
-
-
Imig, J.D.1
Hammock, B.D.2
-
10
-
-
67650073361
-
Overexpression of CYP2J2 provides protection against doxorubicininduced cardiotoxicity
-
Zhang Y, El-Sikhry H, Chaudhary KR, Batchu SN, Shayeganpour A, Jukar TO, Bradbury JA, Graves JP, DeGraff LM, Myers P, Rouse DC, Foley J, Nyska A, Zeldin DC, Seubert JM (2009) Overexpression of CYP2J2 provides protection against doxorubicininduced cardiotoxicity. Am J Physiol Heart Circ Physiol 297:H37-H46.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Zhang, Y.1
El-Sikhry, H.2
Chaudhary, K.R.3
Batchu, S.N.4
Shayeganpour, A.5
Jukar, T.O.6
Bradbury, J.A.7
Graves, J.P.8
Degraff, L.M.9
Myers, P.10
Rouse, D.C.11
Foley, J.12
Nyska, A.13
Zeldin, D.C.14
Seubert, J.M.15
-
11
-
-
84871346041
-
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia
-
Herse F, Lamarca B, Hubel CA, Kaartokallio T, Lokki AI, Ekholm E, Laivuori H, Gauster M, Huppertz B, Sugulle M, Ryan MJ, Novotny S, Brewer J, Park JK, Kacik M, Hoyer J, Verlohren S, Wallukat G, Rothe M, Luft FC, Muller DN, Schunck WH, Staff AC, Dechend R (2012) Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia. Circulation 126:2990-2999.
-
(2012)
Circulation
, vol.126
, pp. 2990-2999
-
-
Herse, F.1
Lamarca, B.2
Hubel, C.A.3
Kaartokallio, T.4
Lokki, A.I.5
Ekholm, E.6
Laivuori, H.7
Gauster, M.8
Huppertz, B.9
Sugulle, M.10
Ryan, M.J.11
Novotny, S.12
Brewer, J.13
Park, J.K.14
Kacik, M.15
Hoyer, J.16
Verlohren, S.17
Wallukat, G.18
Rothe, M.19
Luft, F.C.20
Muller, D.N.21
Schunck, W.H.22
Staff, A.C.23
Dechend, R.24
more..
-
12
-
-
84855453198
-
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
-
Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnes CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC (2012) Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest 122:178-191.
-
(2012)
J Clin Invest
, vol.122
, pp. 178-191
-
-
Panigrahy, D.1
Edin, M.L.2
Lee, C.R.3
Huang, S.4
Bielenberg, D.R.5
Butterfield, C.E.6
Barnes, C.M.7
Mammoto, A.8
Mammoto, T.9
Luria, A.10
Benny, O.11
Chaponis, D.M.12
Dudley, A.C.13
Greene, E.R.14
Vergilio, J.A.15
Pietramaggiori, G.16
Scherer-Pietramaggiori, S.S.17
Short, S.M.18
Seth, M.19
Lih, F.B.20
Tomer, K.B.21
Yang, J.22
Schwendener, R.A.23
Hammock, B.D.24
Falck, J.R.25
Manthati, V.L.26
Ingber, D.E.27
Kaipainen, A.28
D'amore, P.A.29
Kieran, M.W.30
Zeldin, D.C.31
more..
-
13
-
-
83855160837
-
EET signaling in cancer
-
Panigrahy D, Greene ER, Pozzi A, Wang DW, Zeldin DC (2011) EET signaling in cancer. Cancer Metastasis Rev 30:525-540.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 525-540
-
-
Panigrahy, D.1
Greene, E.R.2
Pozzi, A.3
Wang, D.W.4
Zeldin, D.C.5
-
15
-
-
21144459060
-
Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors
-
Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN, Ning YG, Xiao X, Zeldin DC, Wang DW (2005) Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res 65:4707-4715.
-
(2005)
Cancer Res
, vol.65
, pp. 4707-4707
-
-
Jiang, J.G.1
Chen, C.L.2
Card, J.W.3
Yang, S.4
Chen, J.X.5
Fu, X.N.6
Ning, Y.G.7
Xiao, X.8
Zeldin, D.C.9
Wang, D.W.10
-
16
-
-
34547092185
-
Cytochrome p450 epoxygenase promotes human cancer metastasis
-
Jiang JG, Ning YG, Chen C, Ma D, Liu ZJ, Yang S, Zhou J, Xiao X, Zhang XA, Edin ML, Card JW, Wang J, Zeldin DC, Wang DW (2007) Cytochrome p450 epoxygenase promotes human cancer metastasis. Cancer Res 67:6665-6674.
-
(2007)
Cancer Res
, vol.67
, pp. 6665-6674
-
-
Jiang, J.G.1
Ning, Y.G.2
Chen, C.3
Ma, D.4
Liu, Z.J.5
Yang, S.6
Zhou, J.7
Xiao, X.8
Zhang, X.A.9
Edin, M.L.10
Card, J.W.11
Wang, J.12
Zeldin, D.C.13
Wang, D.W.14
-
17
-
-
84859903692
-
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity
-
Lee CA, Jones JP III, Katayama J, Kaspera R, Jiang Y, Freiwald S, Smith E, Walker GS, Totah RA (2012) Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug Metab Dispos 40:943-951.
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 943-951
-
-
Lee, C.A.1
Jones, J.P.2
Katayama, J.3
Kaspera, R.4
Jiang, Y.5
Freiwald, S.6
Smith, E.7
Walker, G.S.8
Totah, R.A.9
-
18
-
-
66749159294
-
Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo
-
Chen C, Li G, Liao W, Wu J, Liu L, Ma D, Zhou J, Elbekai RH, Edin ML, Zeldin DC, Wang DW (2009) Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther 329:908-918.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 908-918
-
-
Chen, C.1
Li, G.2
Liao, W.3
Wu, J.4
Liu, L.5
Ma, D.6
Zhou, J.7
Elbekai, R.H.8
Edin, M.L.9
Zeldin, D.C.10
Wang, D.W.11
-
19
-
-
0036842039
-
Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole
-
Matsumoto S, Hirama T, Matsubara T, Nagata K, Yamazoe Y (2002) Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole. Drug Metab Dispos 30:1240-1245.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1240-1245
-
-
Matsumoto, S.1
Hirama, T.2
Matsubara, T.3
Nagata, K.4
Yamazoe, Y.5
-
20
-
-
0642315074
-
Signals for retention of cytochrome P450 in the endoplasmic reticulum
-
Skorupa E, Kemper B (1998) Signals for retention of cytochrome P450 in the endoplasmic reticulum. Methods Mol Biol 107:251-266.
-
(1998)
Methods Mol Biol
, vol.107
, pp. 251-266
-
-
Skorupa, E.1
Kemper, B.2
-
21
-
-
0036028821
-
Analyzing binding of Nterminal truncated, microsomal cytochrome P450s to membranes
-
Cosme J, Johnson EF (2002) Analyzing binding of Nterminal truncated, microsomal cytochrome P450s to membranes. Methods Enzymol 357:116-120.
-
(2002)
Methods Enzymol
, vol.357
, pp. 116-120
-
-
Cosme, J.1
Johnson, E.F.2
-
22
-
-
0034738973
-
Microsomal cytochrome P450 2C5: Comparison to microbial P450s and unique features
-
Williams PA, Cosme J, Sridhar V, Johnson EF, McRee DE (2000) Microsomal cytochrome P450 2C5: comparison to microbial P450s and unique features. J Inorg Biochem 81:183-190.
-
(2000)
J Inorg Biochem
, vol.81
, pp. 183-190
-
-
Williams, P.A.1
Cosme, J.2
Sridhar, V.3
Johnson, E.F.4
McRee, D.E.5
-
23
-
-
0038690559
-
Protein engineering of thromboxane synthase: Conversion of membrane-bound to soluble form
-
Hsu PY, Wang LH (2003) Protein engineering of thromboxane synthase: conversion of membrane-bound to soluble form. Arch Biochem Biophys 416:38-46.
-
(2003)
Arch Biochem Biophys
, vol.416
, pp. 38-46
-
-
Hsu, P.Y.1
Wang, L.H.2
-
24
-
-
0034723195
-
Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme
-
Cosme J, Johnson EF (2000) Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding. J Biol Chem 275:2545-2553.
-
(2000)
Mutations That Alter Aggregation, Phospholipid Dependence of Catalysis, and Membrane Binding. J Biol Chem
, vol.275
, pp. 2545-2553
-
-
Cosme, J.1
Johnson, E.F.2
-
25
-
-
0031106366
-
Microsomal P450 2C3 is expressed as a soluble dimer in Escherichia coli following modification of its N-terminus
-
von Wachenfeldt C, Richardson TH, Cosme J, Johnson EF (1997) Microsomal P450 2C3 is expressed as a soluble dimer in Escherichia coli following modification of its N-terminus. Arch Biochem Biophys 339:107-114.
-
(1997)
Arch Biochem Biophys
, vol.339
, pp. 107-114
-
-
Von Wachenfeldt, C.1
Richardson, T.H.2
Cosme, J.3
Johnson, E.F.4
-
26
-
-
34147188077
-
Effects of N-terminal modification of recombinant human cytochrome P450 1A2 on catalytic activity
-
Kim HJ, Lee SB, Guengerich FP, Park YI, Dong MS (2007) Effects of N-terminal modification of recombinant human cytochrome P450 1A2 on catalytic activity. Xenobiotica 37:356-365.
-
(2007)
Xenobiotica
, vol.37
, pp. 356-365
-
-
Kim, H.J.1
Lee, S.B.2
Guengerich, F.P.3
Park, Y.I.4
Dong, M.S.5
-
27
-
-
80054709526
-
Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site
-
Berka K, Hendrychova T, Anzenbacher P, Otyepka M (2011) Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site. J Phys Chem A 115:11248-11255.
-
(2011)
J Phys Chem A
, vol.115
, pp. 11248-11255
-
-
Berka, K.1
Hendrychova, T.2
Anzenbacher, P.3
Otyepka, M.4
-
30
-
-
77951903021
-
Membrane protein assembly into Nanodiscs
-
Bayburt TH, Sligar SG (2010) Membrane protein assembly into Nanodiscs. FEBS Lett 584:1721-1727.
-
(2010)
FEBS Lett
, vol.584
, pp. 1721-1727
-
-
Bayburt, T.H.1
Sligar, S.G.2
-
31
-
-
71549142855
-
Chapter 11-Reconstitution of membrane proteins in phospholipid bilayer nanodiscs
-
Ritchie TK, Grinkova YV, Bayburt TH, Denisov IG, Zolnerciks JK, Atkins WM, Sligar SG (2009) Chapter 11-Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Methods Enzymol 464:211-231.
-
(2009)
Methods Enzymol
, vol.464
, pp. 211-231
-
-
Ritchie, T.K.1
Grinkova, Y.V.2
Bayburt, T.H.3
Denisov, I.G.4
Zolnerciks, J.K.5
Atkins, W.M.6
Sligar, S.G.7
-
32
-
-
33745511381
-
Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology
-
Leitz AJ, Bayburt TH, Barnakov AN, Springer BA, Sligar SG (2006) Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology. Biotechniques 40:601-612.
-
(2006)
Biotechniques
, vol.40
, pp. 601-612
-
-
Leitz, A.J.1
Bayburt, T.H.2
Barnakov, A.N.3
Springer, B.A.4
Sligar, S.G.5
-
33
-
-
33746856934
-
Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties
-
Boldog T, Grimme S, Li M, Sligar SG, Hazelbauer GL (2006) Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties. Proc Natl Acad Sci USA 103:11509-11514.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11509-11514
-
-
Boldog, T.1
Grimme, S.2
Li, M.3
Sligar, S.G.4
Hazelbauer, G.L.5
-
34
-
-
33847639732
-
Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins
-
Nath A, Atkins WM, Sligar SG (2007) Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins. Biochemistry 46:2059-2069.
-
(2007)
Biochemistry
, vol.46
, pp. 2059-2069
-
-
Nath, A.1
Atkins, W.M.2
Sligar, S.G.3
-
35
-
-
36148934091
-
Redox potential control by drug binding to cytochrome P450 3A4
-
Das A, Grinkova YV, Sligar SG (2007) Redox potential control by drug binding to cytochrome P450 3A4. J Am Chem Soc 129:13778-13779.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 13778-13779
-
-
Das, A.1
Grinkova, Y.V.2
Sligar, S.G.3
-
36
-
-
73149090794
-
Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer
-
Das A, Sligar SG (2009) Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer. Biochemistry 48:12104-12112.
-
(2009)
Biochemistry
, vol.48
, pp. 12104-12112
-
-
Das, A.1
Sligar, S.G.2
-
37
-
-
77958613305
-
Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs
-
Tark SH, Das A, Sligar S, Dravid VP (2010) Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs. Nanotechnology 21:435502.
-
(2010)
Nanotechnology
, vol.21
, pp. 435502
-
-
Tark, S.H.1
Das, A.2
Sligar, S.3
Dravid, V.P.4
-
38
-
-
84856228232
-
Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs
-
Marty MT, Das A, Sligar SG (2012) Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs. Anal Bioanal Chem 402:721-729.
-
(2012)
Anal Bioanal Chem
, vol.402
, pp. 721-729
-
-
Marty, M.T.1
Das, A.2
Sligar, S.G.3
-
39
-
-
66149100484
-
Screening of type i and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy
-
Das A, Zhao J, Schatz GC, Sligar SG, Van Duyne RP (2009) Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy. Anal Chem 81:3754-3759.
-
(2009)
Anal Chem
, vol.81
, pp. 3754-3759
-
-
Das, A.1
Zhao, J.2
Schatz, G.C.3
Sligar, S.G.4
Van Duyne, R.P.5
-
40
-
-
33748029518
-
Resonance surface plasmon spectroscopy: Low molecular weight substrate binding to cytochrome p450
-
Zhao J, Das A, Zhang X, Schatz GC, Sligar SG, Van Duyne RP (2006) Resonance surface plasmon spectroscopy: low molecular weight substrate binding to cytochrome p450. J Am Chem Soc 128:11004-11005.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 11004-11005
-
-
Zhao, J.1
Das, A.2
Zhang, X.3
Schatz, G.C.4
Sligar, S.G.5
Van Duyne, R.P.6
-
41
-
-
37349017983
-
Heterologous expression and characterization of wild-type human cytochrome P450 1A2 without conventional N-terminal modification in Escherichia coli
-
Kim DH, Kim KH, Isin EM, Guengerich FP, Chae HZ, Ahn T, Yun CH (2008) Heterologous expression and characterization of wild-type human cytochrome P450 1A2 without conventional N-terminal modification in Escherichia coli. Protein Expr Purif 57:188-200.
-
(2008)
Protein Expr Purif
, vol.57
, pp. 188-200
-
-
Kim, D.H.1
Kim, K.H.2
Isin, E.M.3
Guengerich, F.P.4
Chae, H.Z.5
Ahn, T.6
Yun, C.H.7
-
42
-
-
0028846823
-
Universal approach to the expression of human and rabbit cytochrome P450s of the 2c subfamily in Escherichia coli
-
Richardson TH, Jung F, Griffin KJ, Wester M, Raucy JL, Kemper B, Bornheim LM, Hassett C, Omiecinski CJ, Johnson EF (1995) Universal approach to the expression of human and rabbit cytochrome P450s of the 2c subfamily in Escherichia coli. Arch Biochem Biophys 323:87-96.
-
(1995)
Arch Biochem Biophys
, vol.323
, pp. 87-96
-
-
Richardson, T.H.1
Jung, F.2
Griffin, K.J.3
Wester, M.4
Raucy, J.L.5
Kemper, B.6
Bornheim, L.M.7
Hassett, C.8
Omiecinski, C.J.9
Johnson, E.F.10
-
43
-
-
0023395492
-
Influence of the codon following the aug initiation codon on the expression of a modified Lacz gene in Escherichia coli
-
Looman AC, Bodlaender J, Comstock LJ, Eaton D, Jhurani P, Deboer HA, Vanknippenberg PH (1987) Influence of the codon following the aug initiation codon on the expression of a modified Lacz gene in Escherichia coli. EMBO J 6:2489-2492.
-
(1987)
EMBO J
, vol.6
, pp. 2489-2492
-
-
Looman, A.C.1
Bodlaender, J.2
Comstock, L.J.3
Eaton, D.4
Jhurani, P.5
Deboer, H.A.6
Vanknippenberg, P.H.7
-
44
-
-
0025994649
-
Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli
-
Barnes HJ, Arlotto MP, Waterman MR (1991) Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli. Proc Natl Acad Sci USA 88:5597-5601.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5597-5601
-
-
Barnes, H.J.1
Arlotto, M.P.2
Waterman, M.R.3
-
46
-
-
0024344770
-
The role of bases upstream of the Shine-Dalgarno region and in the coding sequence in the control of gene expression in Escherichia coli: Translation and stability of mRNAs in vivo
-
Schauder B, McCarthy JE (1989) The role of bases upstream of the Shine-Dalgarno region and in the coding sequence in the control of gene expression in Escherichia coli: translation and stability of mRNAs in vivo. Gene 78:59-72.
-
(1989)
Gene
, vol.78
, pp. 59-72
-
-
Schauder, B.1
McCarthy, J.E.2
-
47
-
-
2542433007
-
Identification of a novel rat microsomal vitamin D3 25-hydroxylase
-
Yamasaki T, Izumi S, Ide H, Ohyama Y (2004) Identification of a novel rat microsomal vitamin D3 25-hydroxylase. J Biol Chem 279:22848-22856.
-
(2004)
J Biol Chem
, vol.279
, pp. 22848-22856
-
-
Yamasaki, T.1
Izumi, S.2
Ide, H.3
Ohyama, Y.4
-
48
-
-
84856477784
-
Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001
-
DeVore NM, Scott E (2012) Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. Nature 482:116-119.
-
(2012)
Nature
, vol.482
, pp. 116-119
-
-
Devore, N.M.1
Scott, E.2
-
49
-
-
0026601890
-
High-level expression of functional human cytochrome P450 1A2 in Escherichia coli
-
Fisher CW, Caudle DL, Martin-Wixtrom C, Quattrochi LC, Tukey RH, Waterman MR, Estabrook R (1992) High-level expression of functional human cytochrome P450 1A2 in Escherichia coli. FASEB J 6:759-764.
-
(1992)
FASEB J
, vol.6
, pp. 759-764
-
-
Fisher, C.W.1
Caudle, D.L.2
Martin-Wixtrom, C.3
Quattrochi, L.C.4
Tukey, R.H.5
Waterman, M.R.6
Estabrook, R.7
-
50
-
-
75649097836
-
Molecular cloning and enzymatic characterization of sheep CYP2J
-
Messina A, Nencioni S, Gervasi PG, Gotlinger KH, Schwartzman ML, Longo V (2010) Molecular cloning and enzymatic characterization of sheep CYP2J. Xenobiotica 40:109-118.
-
(2010)
Xenobiotica
, vol.40
, pp. 109-118
-
-
Messina, A.1
Nencioni, S.2
Gervasi, P.G.3
Gotlinger, K.H.4
Schwartzman, M.L.5
Longo, V.6
-
51
-
-
0032464019
-
GroEL/GroES: Structure and function of a two-stroke folding machine
-
Xu Z, Sigler P (1998) GroEL/GroES: structure and function of a two-stroke folding machine. J Struct Biol 124:129-141.
-
(1998)
J Struct Biol
, vol.124
, pp. 129-141
-
-
Xu, Z.1
Sigler, P.2
-
53
-
-
0017170343
-
Coupling of spin, substrate, and redox equilibria in cytochrome P450
-
Sligar SG (1976) Coupling of spin, substrate, and redox equilibria in cytochrome P450. Biochemistry 15:5399-5406.
-
(1976)
Biochemistry
, vol.15
, pp. 5399-5406
-
-
Sligar, S.G.1
-
54
-
-
34147112191
-
Cooperativity in cytochrome P450 3A4: Linkages in substrate binding, spin state, uncoupling, and product formation
-
Denisov IG, Baas BJ, Grinkova YV, Sligar SG (2007) Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation. J Biol Chem 282:7066-7076.
-
(2007)
J Biol Chem
, vol.282
, pp. 7066-7076
-
-
Denisov, I.G.1
Baas, B.J.2
Grinkova, Y.V.3
Sligar, S.G.4
-
55
-
-
0030923112
-
Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes
-
Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR, Zeldin DC (1997) Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J Biol Chem 272:12551-12559.
-
(1997)
J Biol Chem
, vol.272
, pp. 12551-12559
-
-
Wu, S.1
Chen, W.2
Murphy, E.3
Gabel, S.4
Tomer, K.B.5
Foley, J.6
Steenbergen, C.7
Falck, J.R.8
Moomaw, C.R.9
Zeldin, D.C.10
-
56
-
-
47749092044
-
Determinants of cytochrome P450 2C8 substrate binding: Structures of complexes with montelukast, troglitazone, felodipine, and 9-cisretinoic acid
-
Schoch GA, Yano JK, Sansen S, Dansette PM, Stout CD, Johnson EF (2008) Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cisretinoic acid. J Biol Chem 283:17227-17237.
-
(2008)
J Biol Chem
, vol.283
, pp. 17227-17237
-
-
Schoch, G.A.1
Yano, J.K.2
Sansen, S.3
Dansette, P.M.4
Stout, C.D.5
Johnson, E.F.6
-
57
-
-
1542364450
-
Structure of human microsomal cytochrome P450 2C8
-
Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF (2004) Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem 279:9497-9503.
-
(2004)
Evidence for A Peripheral Fatty Acid Binding Site. J Biol Chem
, vol.279
, pp. 9497-9503
-
-
Schoch, G.A.1
Yano, J.K.2
Wester, M.R.3
Griffin, K.J.4
Stout, C.D.5
Johnson, E.F.6
-
58
-
-
0036138172
-
Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes
-
Hashizume T, Imaoka S, Mise M, Terauchi Y, Fujii T, Miyazaki H, Kamataki T, Funae Y (2002) Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes. J Pharmacol Exp Ther 300:298-304.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 298-304
-
-
Hashizume, T.1
Imaoka, S.2
Mise, M.3
Terauchi, Y.4
Fujii, T.5
Miyazaki, H.6
Kamataki, T.7
Funae, Y.8
-
59
-
-
63849246525
-
Protein structure prediction on the Web: A case study using the Phyre server
-
Kelley LA, Sternberg M (2009) Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc 4:363-371.
-
(2009)
Nat Protoc
, vol.4
, pp. 363-371
-
-
Kelley, L.A.1
Sternberg, M.2
-
61
-
-
8844229574
-
Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry
-
Kang W, Liu KH, Ryu JY, Shin J (2004) Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 813:75-80.
-
(2004)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.813
, pp. 75-80
-
-
Kang, W.1
Liu, K.H.2
Ryu, J.Y.3
Shin, J.4
-
62
-
-
33751112296
-
Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: Major roles for CYP2J2 and CYP3A
-
Liu KH, Kim MG, Lee DJ, Yoon YJ, Kim MJ, Shon JH, Choi CS, Choi YK, Desta Z, Shin JG (2006) Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A. Drug Metab Dispos 34:1793-1797.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1793-1797
-
-
Liu, K.H.1
Kim, M.G.2
Lee, D.J.3
Yoon, Y.J.4
Kim, M.J.5
Shon, J.H.6
Choi, C.S.7
Choi, Y.K.8
Desta, Z.9
Shin, J.G.10
-
64
-
-
21344472349
-
Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds
-
Sulistyaningdyah WT, Ogawa J, Li QS, Maeda C, Yano Y, Schmid RD, Shimizu S (2005) Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds. Appl Microbiol Biotechnol 67:556-562.
-
(2005)
Appl Microbiol Biotechnol
, vol.67
, pp. 556-562
-
-
Sulistyaningdyah, W.T.1
Ogawa, J.2
Li, Q.S.3
Maeda, C.4
Yano, Y.5
Schmid, R.D.6
Shimizu, S.7
-
65
-
-
54949132112
-
Substrate binding to cytochromes P450
-
Isin EM, Guengerich FP (2008) Substrate binding to cytochromes P450. Anal Bioanal Chem 392:1019-1030.
-
(2008)
Anal Bioanal Chem
, vol.392
, pp. 1019-1030
-
-
Isin, E.M.1
Guengerich, F.P.2
-
66
-
-
33845379583
-
Control of heme protein redox potential and reduction rate-linear free-energy relation between potential and ferric spin state equilibrium
-
Fisher MT, Sligar SG (1985) Control of heme protein redox potential and reduction rate-linear free-energy relation between potential and ferric spin state equilibrium. J Am Chem Soc 107:5018-5019.
-
(1985)
J Am Chem Soc
, vol.107
, pp. 5018-5019
-
-
Fisher, M.T.1
Sligar, S.G.2
-
67
-
-
0032479307
-
Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase
-
Bridges A, Gruenke L, Chang YT, Vakser IA, Loew G, Waskell L (1998) Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase. J Biol Chem 273:17036-17049.
-
(1998)
J Biol Chem
, vol.273
, pp. 17036-17049
-
-
Bridges, A.1
Gruenke, L.2
Chang, Y.T.3
Vakser, I.A.4
Loew, G.5
Waskell, L.6
-
68
-
-
0027216444
-
Role of lysine and arginine residues of cytochrome P450 in the interaction between cytochrome P4502B1 and NADPH-cytochrome P450 reductase
-
Shen S, Strobel HW (1993) Role of lysine and arginine residues of cytochrome P450 in the interaction between cytochrome P4502B1 and NADPH-cytochrome P450 reductase. Arch Biochem Biophys 304:257-265.
-
(1993)
Arch Biochem Biophys
, vol.304
, pp. 257-265
-
-
Shen, S.1
Strobel, H.W.2
-
70
-
-
0029763064
-
Approaches to crystallizing P450s
-
Poulos TL (1996) Approaches to crystallizing P450s. Methods Enzymol 272:358-368.
-
(1996)
Methods Enzymol
, vol.272
, pp. 358-368
-
-
Poulos, T.L.1
-
72
-
-
33747863597
-
Characterization of rat and human CYP2J enzymes as vitamin D 25-hydroxylases
-
Aiba I, Yamasaki T, Shinki T, Izumi S, Yamamoto K, Yamada S, Terato H, Ide H, Ohyama Y (2006) Characterization of rat and human CYP2J enzymes as vitamin D 25-hydroxylases. Steroids 71:849-856.
-
(2006)
Steroids
, vol.71
, pp. 849-856
-
-
Aiba, I.1
Yamasaki, T.2
Shinki, T.3
Izumi, S.4
Yamamoto, K.5
Yamada, S.6
Terato, H.7
Ide, H.8
Ohyama, Y.9
-
73
-
-
0035883794
-
Osmotic stress induced by carbohydrates enhances expression of foreign proteins in Escherichia coli
-
Kagawa N, Cao Q (2001) Osmotic stress induced by carbohydrates enhances expression of foreign proteins in Escherichia coli. Arch Biochem Biophys 393:290-296.
-
(2001)
Arch Biochem Biophys
, vol.393
, pp. 290-296
-
-
Kagawa, N.1
Cao, Q.2
-
74
-
-
45449113739
-
Bacterial expression and purification of interleukin-2 tyrosine kinase: Single step separation of the chaperonin impurity
-
Joseph RE, Andreotti AH (2008) Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurity. Protein Expr Purif 60:194-197.
-
(2008)
Protein Expr Purif
, vol.60
, pp. 194-197
-
-
Joseph, R.E.1
Andreotti, A.H.2
-
75
-
-
0025302128
-
Dual role of phospholipid in the reconstitution of cytochrome P-450 LM2-dependent activities
-
Causey KM, Eyer CS, Backes WL (1990) Dual role of phospholipid in the reconstitution of cytochrome P-450 LM2-dependent activities. Mol Pharmacol 38:134-142.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 134-142
-
-
Causey, K.M.1
Eyer, C.S.2
Backes, W.L.3
-
76
-
-
0035711194
-
Tobacco etch virus protease: Mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency
-
Kapust RB, Tozser J, Fox JD, Anderson DE, Cherry S, Copeland TD, Waugh D (2001) Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency. Protein Eng 14:993-1000.
-
(2001)
Protein Eng
, vol.14
, pp. 993-1000
-
-
Kapust, R.B.1
Tozser, J.2
Fox, J.D.3
Anderson, D.E.4
Cherry, S.5
Copeland, T.D.6
Waugh, D.7
|