Antitumor effect of Japanese apricot extract (MK615) on human cancer cells in vitro and in vivo through a reactive oxygen species-dependent mechanism

Tumori

Volumn 99, Issue 2, 2013, Pages 239-248

  Hattori, Miho ^a   Kawakami, Koshi ^a   Akimoto, Miho ^a   Takenaga, Keizo ^a   Suzumiya, Junji ^a   Honma, Yoshio ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

Combination therapy; Gemcitabine; Japanese apricot extract; Pancreatic cancer; Reactive oxygen species; Triterpene; Xenograft

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; BETULIC ACID; GEMCITABINE; INDOMETACIN; LUPEOL; MISATOL; OLEANOLIC ACID; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; URSOLIC ACID; DEOXYCYTIDINE; DRUG DERIVATIVE; MK615 EXTRACT;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BONE MARROW CELL; CANCER CELL; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PANCREAS CANCER; UMBILICAL VEIN ENDOTHELIAL CELL; BREAST TUMOR; DRUG EFFECT; FEMALE; LUNG TUMOR; MALE; METABOLISM; NEOPLASM; OVARY TUMOR; PANCREAS TUMOR; PRUNUS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CELL LINE, TUMOR; DEOXYCYTIDINE; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; NEOPLASMS; OVARIAN NEOPLASMS; PANCREATIC NEOPLASMS; PLANT EXTRACTS; PRUNUS; REACTIVE OXYGEN SPECIES;

MLCS; MLOWN;

EID: 84881237288     PISSN: 03008916     EISSN: 20382529     Source Type: Journal    
DOI: 10.1700/1283.14199     Document Type: Article

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