Identification of an allosteric modulator of the serotonin transporter with novel mechanism of action

Neuropharmacology

Volumn 72, Issue , 2013, Pages 282-290

  Kortagere, Sandhya ^a   Fontana, Andreia Cristina Karklin ^a   Renée Rose, Deja ^a   Mortensen, Ole Valente ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Allosteric modulator; Hybrid structure based method; Molecular dynamics; Monoamine transporters; Psychostimulants; Virtual screening

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ATM 7; SEROTONIN RECEPTOR AFFECTING AGENT; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID ANALYSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA TEMPLATE; DRUG BINDING SITE; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; ENZYME SUBSTRATE COMPLEX; EXTRACELLULAR SPACE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; SEROTONIN UPTAKE; SITE DIRECTED MUTAGENESIS; VIRTUAL REALITY;

EID: 84881168900     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.04.026     Document Type: Article

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