메뉴 건너뛰기




Volumn 77, Issue 1, 2014, Pages 39-54

Phosphate: An old bone molecule but new cardiovascular risk factor

Author keywords

cardiovascular disease; chronic kidney disease; hyperphosphataemia; phosphate; SLC20 (PiT1 and 2); vascular calcification

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CALCITRIOL; CINACALCET; FARNOQUINONE; LANTHANUM CARBONATE; PHOSPHATE; PHOSPHATE TRANSPORTER; PLACEBO; PYROPHOSPHATE; TRANSCRIPTION FACTOR PIT 1; TRANSCRIPTION FACTOR PIT 2; UNCLASSIFIED DRUG; VITAMIN D; CALCIMIMETIC AGENT; CHELATING AGENT;

EID: 84881167256     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12117     Document Type: Article
Times cited : (21)

References (174)
  • 4
    • 0017584263 scopus 로고
    • The pathophysiology and clinical characteristics of severe hypophosphatemia
    • Knochel JP,. The pathophysiology and clinical characteristics of severe hypophosphatemia. Arch Intern Med 1977; 137: 203-220.
    • (1977) Arch Intern Med , vol.137 , pp. 203-220
    • Knochel, J.P.1
  • 5
    • 8644278672 scopus 로고    scopus 로고
    • Sodium-phosphate cotransporters, nephrolithiasis and bone demineralization
    • Prié D, Beck L, Friedlander G, Silve C,. Sodium-phosphate cotransporters, nephrolithiasis and bone demineralization. Curr Opin Nephrol Hypertens 2004; 13: 675-681.
    • (2004) Curr Opin Nephrol Hypertens , vol.13 , pp. 675-681
    • Prié, D.1    Beck, L.2    Friedlander, G.3    Silve, C.4
  • 6
    • 27444436252 scopus 로고    scopus 로고
    • Relation between serum phosphate level and cardiovascular event rate in people with coronary disease
    • Tonelli M, Sacks F, Pfeffer M, Gao Z, Curhan G,. Relation between serum phosphate level and cardiovascular event rate in people with coronary disease. Circulation 2005; 112: 2627-2633.
    • (2005) Circulation , vol.112 , pp. 2627-2633
    • Tonelli, M.1    Sacks, F.2    Pfeffer, M.3    Gao, Z.4    Curhan, G.5
  • 11
    • 60449096473 scopus 로고    scopus 로고
    • Serum phosphate and left ventricular hypertrophy in young adults: The coronary artery risk development in young adults study
    • Foley RN, Collins AJ, Herzog CA, Ishani A, Kalra PA,. Serum phosphate and left ventricular hypertrophy in young adults: the coronary artery risk development in young adults study. Kidney Blood Press Res 2009; 32: 37-44.
    • (2009) Kidney Blood Press Res , vol.32 , pp. 37-44
    • Foley, R.N.1    Collins, A.J.2    Herzog, C.A.3    Ishani, A.4    Kalra, P.A.5
  • 12
    • 69249231159 scopus 로고    scopus 로고
    • Phosphate levels and cardiovascular disease in the general population
    • Foley RN,. Phosphate levels and cardiovascular disease in the general population. Clin J Am Soc Nephrol. 2009; 4: 1136-1139.
    • (2009) Clin J Am Soc Nephrol. , vol.4 , pp. 1136-1139
    • Foley, R.N.1
  • 13
    • 0018547632 scopus 로고
    • The enzymatic replication of DNA
    • Kornberg A,. The enzymatic replication of DNA. CRC Crit Rev Biochem 1979; 7: 23-43.
    • (1979) CRC Crit Rev Biochem , vol.7 , pp. 23-43
    • Kornberg, A.1
  • 16
    • 0018337894 scopus 로고
    • Phosphorylation-dephosphorylation of enzymes
    • Krebs EG, Beavo JA,. Phosphorylation-dephosphorylation of enzymes. Annu Rev Biochem 1979; 48: 923-959.
    • (1979) Annu Rev Biochem , vol.48 , pp. 923-959
    • Krebs, E.G.1    Beavo, J.A.2
  • 17
    • 0033786922 scopus 로고    scopus 로고
    • Protein tyrosine kinase structure and function
    • Hubbard SR, Till JH,. Protein tyrosine kinase structure and function. Annu Rev Biochem 2000; 69: 373-398.
    • (2000) Annu Rev Biochem , vol.69 , pp. 373-398
    • Hubbard, S.R.1    Till, J.H.2
  • 18
    • 0141783912 scopus 로고
    • Hidden sources of phosphorus in the typical American diet: Does it matter in nephrology?
    • Uribarri J, Calvo MS,. Hidden sources of phosphorus in the typical American diet: does it matter in nephrology? Semin Dial 1990; 16: 186-188.
    • (1990) Semin Dial , vol.16 , pp. 186-188
    • Uribarri, J.1    Calvo, M.S.2
  • 20
    • 0027160146 scopus 로고
    • Expression cloning of human and rat renal cortex Na/Pi cotransport
    • Magagnin S,. Expression cloning of human and rat renal cortex Na/Pi cotransport. Proc Natl Acad Sci U S A 1993; 90: 5979-5983.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5979-5983
    • Magagnin, S.1
  • 21
    • 0028341123 scopus 로고
    • Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters
    • Kavanaugh MP, Miller DG, Zhang W, Law W, Kozak SL, Kabat D, Miller D,. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters. Proc Natl Acad Sci U S A 1994; 91: 7071-7075.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7071-7075
    • Kavanaugh, M.P.1    Miller, D.G.2    Zhang, W.3    Law, W.4    Kozak, S.L.5    Kabat, D.6    Miller, D.7
  • 22
    • 0029930912 scopus 로고    scopus 로고
    • Identification and characterization of a widely expressed phosphate transporter/retrovirus receptor family
    • Kavanaugh MP, Kabat D,. Identification and characterization of a widely expressed phosphate transporter/retrovirus receptor family. Kidney Int 1996; 49: 959-963.
    • (1996) Kidney Int , vol.49 , pp. 959-963
    • Kavanaugh, M.P.1    Kabat, D.2
  • 26
    • 34547735935 scopus 로고    scopus 로고
    • Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements
    • Ravera S, Virkki LV, Murer H, Forster IC,. Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements. Am J Physiol Cell Physiol 2007; 293: C606-620.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Ravera, S.1    Virkki, L.V.2    Murer, H.3    Forster, I.C.4
  • 27
    • 0017747466 scopus 로고
    • Role of 1,25-dihydroxyvitamin D3 on intestinal phosphate absorption in rats with a normal vitamin D supply
    • Rizzoli R, Fleisch H, Bonjour JP,. Role of 1,25-dihydroxyvitamin D3 on intestinal phosphate absorption in rats with a normal vitamin D supply. J Clin Invest 1977; 60: 639-647.
    • (1977) J Clin Invest , vol.60 , pp. 639-647
    • Rizzoli, R.1    Fleisch, H.2    Bonjour, J.P.3
  • 28
    • 0141844575 scopus 로고    scopus 로고
    • Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX
    • Liu S, Guo R, Simpson LG, Xiao Z-S, Burnham CE, Quarles LD,. Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX. J Biol Chem 2003; 278: 37419-37426.
    • (2003) J Biol Chem , vol.278 , pp. 37419-37426
    • Liu, S.1    Guo, R.2    Simpson, L.G.3    Xiao, Z.-S.4    Burnham, C.E.5    Quarles, L.D.6
  • 29
    • 8444223088 scopus 로고    scopus 로고
    • Bone as a source of FGF23: Regulation by phosphate?
    • Mirams M, Robinson BG, Mason RS, Nelson AE,. Bone as a source of FGF23: regulation by phosphate? Bone 2004; 35: 1192-1199.
    • (2004) Bone , vol.35 , pp. 1192-1199
    • Mirams, M.1    Robinson, B.G.2    Mason, R.S.3    Nelson, A.E.4
  • 33
    • 3042634460 scopus 로고    scopus 로고
    • Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis
    • Larsson T, Marsell R, Schipani E, Ohlsson C, Ljunggren O, Tenenhouse HS, Jüppner H, Jonsson KB,. Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis. Endocrinology 2004; 145: 3087-3094.
    • (2004) Endocrinology , vol.145 , pp. 3087-3094
    • Larsson, T.1    Marsell, R.2    Schipani, E.3    Ohlsson, C.4    Ljunggren, O.5    Tenenhouse, H.S.6    Jüppner, H.7    Jonsson, K.B.8
  • 35
    • 34250667000 scopus 로고    scopus 로고
    • Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice
    • Stubbs JR, Liu S, Tang W, Zhou J, Wang Y, Yao X, Quarles LD,. Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice. J Am Soc Nephrol 2007; 18: 2116-2124.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2116-2124
    • Stubbs, J.R.1    Liu, S.2    Tang, W.3    Zhou, J.4    Wang, Y.5    Yao, X.6    Quarles, L.D.7
  • 38
    • 65649103814 scopus 로고    scopus 로고
    • Initial FGF23-mediated signaling occurs in the distal convoluted tubule
    • Farrow EG, Davis SI, Summers LJ, White KE,. Initial FGF23-mediated signaling occurs in the distal convoluted tubule. J Am Soc Nephrol 2009; 20: 955-960.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 955-960
    • Farrow, E.G.1    Davis, S.I.2    Summers, L.J.3    White, K.E.4
  • 40
    • 36049037977 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro
    • Perwad F, Zhang MYH, Tenenhouse HS, Portale AA,. Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro. Am J Physiol Renal Physiol 2007; 293: F1577-1583.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Perwad, F.1    Zhang, M.Y.H.2    Tenenhouse, H.S.3    Portale, A.A.4
  • 43
    • 0002869763 scopus 로고    scopus 로고
    • Vitamin D: From photosynthesis, metabolism, and action to clinical applications
    • eds DeGroot L.J. Jameson J.L. Philadelphia, PA: W.B. Saunders
    • Bouillon R,. Vitamin D: from photosynthesis, metabolism, and action to clinical applications. In: Endocrinology eds, DeGroot LJ, Jameson JL,. Philadelphia, PA: W.B. Saunders 2001; 1009-1028.
    • (2001) Endocrinology , pp. 1009-1028
    • Bouillon, R.1
  • 44
    • 77951920659 scopus 로고    scopus 로고
    • Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23
    • Bergwitz C, Jüppner H,. Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23. Annu Rev Med 2010; 61: 91-104.
    • (2010) Annu Rev Med , vol.61 , pp. 91-104
    • Bergwitz, C.1    Jüppner, H.2
  • 45
    • 0031660004 scopus 로고    scopus 로고
    • Parathyroid hormone and dietary phosphate provoke a lysosomal routing of the proximal tubular Na/Pi-cotransporter type II
    • Keusch I, Traebert M, Lötscher M, Kaissling B, Murer H, Biber J,. Parathyroid hormone and dietary phosphate provoke a lysosomal routing of the proximal tubular Na/Pi-cotransporter type II. Kidney Int 1998; 54: 1224-1232.
    • (1998) Kidney Int , vol.54 , pp. 1224-1232
    • Keusch, I.1    Traebert, M.2    Lötscher, M.3    Kaissling, B.4    Murer, H.5    Biber, J.6
  • 46
    • 0032539622 scopus 로고    scopus 로고
    • Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter
    • Pfister MF,. Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter. Proc Natl Acad Sci U S A 1998; 95: 1909-1914.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1909-1914
    • Pfister, M.F.1
  • 47
    • 0025268141 scopus 로고
    • PTH receptor coupling to phospholipase C is an alternate pathway of signal transduction in bone and kidney
    • Dunlay R, Hruska K,. PTH receptor coupling to phospholipase C is an alternate pathway of signal transduction in bone and kidney. Am J Physiol Renal Physiol 1990; 258: F223-231.
    • (1990) Am J Physiol Renal Physiol , vol.258
    • Dunlay, R.1    Hruska, K.2
  • 48
    • 0030044881 scopus 로고    scopus 로고
    • Parathyroid hormone stimulation of calcium transport is mediated by dual signaling mechanisms involving protein kinase A and protein kinase C
    • Friedman PA,. Parathyroid hormone stimulation of calcium transport is mediated by dual signaling mechanisms involving protein kinase A and protein kinase C. Endocrinology 1996; 137: 13-20.
    • (1996) Endocrinology , vol.137 , pp. 13-20
    • Friedman, P.A.1
  • 49
    • 0037142080 scopus 로고    scopus 로고
    • Na(+)/H(+) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling
    • Mahon MJ, Donowitz M, Yun CC, Segre GV,. Na(+)/H(+) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling. Nature 2002; 417: 858-861.
    • (2002) Nature , vol.417 , pp. 858-861
    • Mahon, M.J.1    Donowitz, M.2    Yun, C.C.3    Segre, G.V.4
  • 50
    • 0141864344 scopus 로고    scopus 로고
    • Inorganic phosphate as a signaling molecule in osteoblast differentiation
    • Beck GR,. Inorganic phosphate as a signaling molecule in osteoblast differentiation. J Cell Biochem 2003; 90: 234-243.
    • (2003) J Cell Biochem , vol.90 , pp. 234-243
    • Beck, G.R.1
  • 51
    • 0015953347 scopus 로고
    • Bone growth in organ culture: Effects of phosphate and other nutrients on bone and cartilage
    • Bingham PJ, Raisz LG,. Bone growth in organ culture: effects of phosphate and other nutrients on bone and cartilage. Calcif Tissue Res 1974; 14: 31-48.
    • (1974) Calcif Tissue Res , vol.14 , pp. 31-48
    • Bingham, P.J.1    Raisz, L.G.2
  • 52
    • 0026559372 scopus 로고
    • Inorganic phosphate added exogenously or released from β-glycerophosphate initiates mineralization of osteoid nodules in vitro
    • Bellows CG, Heersche JNM, Aubin JE,. Inorganic phosphate added exogenously or released from β-glycerophosphate initiates mineralization of osteoid nodules in vitro. Bone Miner 1992; 17: 15-29.
    • (1992) Bone Miner , vol.17 , pp. 15-29
    • Bellows, C.G.1    Heersche, J.N.M.2    Aubin, J.E.3
  • 53
    • 0033662188 scopus 로고    scopus 로고
    • Cbfa1: A molecular switch in osteoblast biology
    • Ducy P,. Cbfa1: a molecular switch in osteoblast biology. Dev Dyn 2000; 219: 461-471.
    • (2000) Dev Dyn , vol.219 , pp. 461-471
    • Ducy, P.1
  • 54
    • 0042665576 scopus 로고    scopus 로고
    • Inorganic phosphate regulates multiple genes during osteoblast differentiation, including Nrf2
    • Beck G,. Inorganic phosphate regulates multiple genes during osteoblast differentiation, including Nrf2. Exp Cell Res 2003; 288: 288-300.
    • (2003) Exp Cell Res , vol.288 , pp. 288-300
    • Beck, G.1
  • 55
    • 0026653092 scopus 로고
    • Osteogenic phase-specific co-regulation of collagen synthesis and mineralization by β-glycerophosphate in chick periosteal cultures
    • Tenenbaum HC, Limeback H, McCulloch CAG, Mamujee H, Sukhu B, Torontali M,. Osteogenic phase-specific co-regulation of collagen synthesis and mineralization by β-glycerophosphate in chick periosteal cultures. Bone 1992; 13: 129-138.
    • (1992) Bone , vol.13 , pp. 129-138
    • Tenenbaum, H.C.1    Limeback, H.2    McCulloch, C.A.G.3    Mamujee, H.4    Sukhu, B.5    Torontali, M.6
  • 56
    • 0026536882 scopus 로고
    • Studies of mineralization in tissue culture: Optimal conditions for cartilage calcification
    • Boskey AL, Stiner D, Doty SB, Binderman I, Leboy P,. Studies of mineralization in tissue culture: optimal conditions for cartilage calcification. Bone Miner 1992; 16: 11-36.
    • (1992) Bone Miner , vol.16 , pp. 11-36
    • Boskey, A.L.1    Stiner, D.2    Doty, S.B.3    Binderman, I.4    Leboy, P.5
  • 58
    • 0029061758 scopus 로고
    • Molecular biology of matrix vesicles
    • Anderson HC,. Molecular biology of matrix vesicles. Clin Orthop Relat Res 1995; 314: 266-280.
    • (1995) Clin Orthop Relat Res , vol.314 , pp. 266-280
    • Anderson, H.C.1
  • 59
    • 0029999082 scopus 로고    scopus 로고
    • Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism
    • Caverzasio J, Bonjour J,. Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism. Kidney Int 1996; 49: 975-980.
    • (1996) Kidney Int , vol.49 , pp. 975-980
    • Caverzasio, J.1    Bonjour, J.2
  • 60
    • 0030537068 scopus 로고    scopus 로고
    • Functional role of Pi transport in osteogenic cells
    • Caverzasio J, Montessuit C, Bonjour J-P,. Functional role of Pi transport in osteogenic cells. Physiology. 1996; 11: 119-125.
    • (1996) Physiology. , vol.11 , pp. 119-125
    • Caverzasio, J.1    Montessuit, C.2    Bonjour, J.-P.3
  • 61
    • 0035122861 scopus 로고    scopus 로고
    • Gene array analysis of osteoblast differentiation
    • Beck GR, Zerler B, Moran E,. Gene array analysis of osteoblast differentiation. Cell Growth Differ 2001; 12: 61-83.
    • (2001) Cell Growth Differ , vol.12 , pp. 61-83
    • Beck, G.R.1    Zerler, B.2    Moran, E.3
  • 62
    • 0142149155 scopus 로고    scopus 로고
    • Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent
    • Beck GR, Knecht N,. Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent. J Biol Chem 2003; 278: 41921-41929.
    • (2003) J Biol Chem , vol.278 , pp. 41921-41929
    • Beck, G.R.1    Knecht, N.2
  • 64
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X, Yang H-Y, Giachelli CM,. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 2006; 98: 905-912.
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.-Y.2    Giachelli, C.M.3
  • 65
    • 71449092846 scopus 로고    scopus 로고
    • Identification of a novel function of PiT1 critical for cell proliferation and independent of its phosphate transport activity
    • Beck L, Leroy C, Salaün C, Margall-Ducos G, Desdouets C, Friedlander G,. Identification of a novel function of PiT1 critical for cell proliferation and independent of its phosphate transport activity. J Biol Chem 2009; 284: 31363-31374.
    • (2009) J Biol Chem , vol.284 , pp. 31363-31374
    • Beck, L.1    Leroy, C.2    Salaün, C.3    Margall-Ducos, G.4    Desdouets, C.5    Friedlander, G.6
  • 66
    • 33646265494 scopus 로고    scopus 로고
    • Enhanced expression of the inorganic phosphate transporter Pit-1 is involved in BMP-2-induced matrix mineralization in osteoblast-like cells
    • Cells O, Suzuki A, Ghayor C, Guicheux J, Magne D, Quillard S, Kakita A,. Enhanced expression of the inorganic phosphate transporter Pit-1 is involved in BMP-2-induced matrix mineralization in osteoblast-like cells. J Bone Miner Res 2006; 21: 674-683.
    • (2006) J Bone Miner Res , vol.21 , pp. 674-683
    • Cells, O.1    Suzuki, A.2    Ghayor, C.3    Guicheux, J.4    Magne, D.5    Quillard, S.6    Kakita, A.7
  • 67
    • 34250613172 scopus 로고    scopus 로고
    • Sodium-dependent phosphate cotransporters and vascular calcification
    • Li X, Giachelli CM,. Sodium-dependent phosphate cotransporters and vascular calcification. Curr Opin Nephrol Hypertens 2007; 16: 325-328.
    • (2007) Curr Opin Nephrol Hypertens , vol.16 , pp. 325-328
    • Li, X.1    Giachelli, C.M.2
  • 68
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz S, Speer MY, Curinga G, Yang H-Y, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM,. Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res 2001; 89: 1147-1154.
    • (2001) Circ Res , vol.89 , pp. 1147-1154
    • Steitz, S.1    Speer, M.Y.2    Curinga, G.3    Yang, H.-Y.4    Haynes, P.5    Aebersold, R.6    Schinke, T.7    Karsenty, G.8    Giachelli, C.M.9
  • 72
    • 40949158527 scopus 로고    scopus 로고
    • BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells
    • Li X, Yang H-Y, Giachelli CM,. BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. Atherosclerosis 2008; 199: 271-277.
    • (2008) Atherosclerosis , vol.199 , pp. 271-277
    • Li, X.1    Yang, H.-Y.2    Giachelli, C.M.3
  • 77
    • 1642313676 scopus 로고    scopus 로고
    • Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: An integrated model of the pathogenesis of mineralization disorders
    • Harmey D, Hessle L, Narisawa S, Johnson KA, Terkeltaub R, Millán JL,. Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol 2004; 164: 1199-1209.
    • (2004) Am J Pathol , vol.164 , pp. 1199-1209
    • Harmey, D.1    Hessle, L.2    Narisawa, S.3    Johnson, K.A.4    Terkeltaub, R.5    Millán, J.L.6
  • 78
    • 33745911180 scopus 로고    scopus 로고
    • Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease
    • Mathew S, Davies M, Lund R, Saab G, Hruska KA,. Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease. Eur J Clin Invest 2006; 36: (Suppl 2): 43-50.
    • (2006) Eur J Clin Invest , vol.36 , Issue.SUPPL. 2 , pp. 43-50
    • Mathew, S.1    Davies, M.2    Lund, R.3    Saab, G.4    Hruska, K.A.5
  • 80
    • 0027367239 scopus 로고
    • Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques
    • Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM,. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest 1993; 92: 1686-1696.
    • (1993) J Clin Invest , vol.92 , pp. 1686-1696
    • Giachelli, C.M.1    Bae, N.2    Almeida, M.3    Denhardt, D.T.4    Alpers, C.E.5    Schwartz, S.M.6
  • 83
    • 2942666581 scopus 로고    scopus 로고
    • Phosphate uptake and PiT-1 protein expression in rat skeletal muscle
    • Abraham K, Brault JJ, Terjung RL,. Phosphate uptake and PiT-1 protein expression in rat skeletal muscle. Am J Physiol Cell Physiol 2004; 287: C73-78.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Abraham, K.1    Brault, J.J.2    Terjung, R.L.3
  • 84
    • 78951478417 scopus 로고    scopus 로고
    • Cellular ATP synthesis mediated by type III sodium-dependent phosphate transporter Pit-1 is critical to chondrogenesis
    • Sugita A, Kawai S, Hayashibara T, Amano A, Ooshima T, Michigami T, Yoshikawa H, Yoneda T,. Cellular ATP synthesis mediated by type III sodium-dependent phosphate transporter Pit-1 is critical to chondrogenesis. J Biol Chem 2011; 286: 3094-3103.
    • (2011) J Biol Chem , vol.286 , pp. 3094-3103
    • Sugita, A.1    Kawai, S.2    Hayashibara, T.3    Amano, A.4    Ooshima, T.5    Michigami, T.6    Yoshikawa, H.7    Yoneda, T.8
  • 85
    • 3042844136 scopus 로고    scopus 로고
    • Regulation of phosphate (Pi) transport and NaPi-III transporter (Pit-1) mRNA in rat osteoblasts
    • Zoidis E, Ghirlanda-Keller C, Gosteli-Peter M, Zapf J, Schmid C,. Regulation of phosphate (Pi) transport and NaPi-III transporter (Pit-1) mRNA in rat osteoblasts. J Endocrinol 2004; 181: 531-540.
    • (2004) J Endocrinol , vol.181 , pp. 531-540
    • Zoidis, E.1    Ghirlanda-Keller, C.2    Gosteli-Peter, M.3    Zapf, J.4    Schmid, C.5
  • 86
    • 77949261522 scopus 로고    scopus 로고
    • Dexamethasone and cyclic AMP regulate sodium phosphate cotransporter (NaPi-IIb and Pit-1) mRNA and phosphate uptake in rat alveolar type II epithelial cells
    • Jin C, Zoidis E, Ghirlanda C, Schmid C,. Dexamethasone and cyclic AMP regulate sodium phosphate cotransporter (NaPi-IIb and Pit-1) mRNA and phosphate uptake in rat alveolar type II epithelial cells. Lung 2010; 188: 51-61.
    • (2010) Lung , vol.188 , pp. 51-61
    • Jin, C.1    Zoidis, E.2    Ghirlanda, C.3    Schmid, C.4
  • 88
    • 34250197188 scopus 로고    scopus 로고
    • Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization
    • Yoshiko Y, Candeliere GA, Maeda N, Aubin JE,. Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization. Mol Cell Biol 2007; 27: 4465-4474.
    • (2007) Mol Cell Biol , vol.27 , pp. 4465-4474
    • Yoshiko, Y.1    Candeliere, G.A.2    Maeda, N.3    Aubin, J.E.4
  • 89
    • 0036227649 scopus 로고    scopus 로고
    • Pit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentration
    • Salaun C, Gyan E, Rodrigues P, Heard JM,. Pit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentration. J Virol 2002; 76: 4304-4311.
    • (2002) J Virol , vol.76 , pp. 4304-4311
    • Salaun, C.1    Gyan, E.2    Rodrigues, P.3    Heard, J.M.4
  • 90
    • 73649138204 scopus 로고    scopus 로고
    • Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1
    • Festing MH, Speer MY, Yang H-Y, Giachelli CM,. Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. Genesis 2009; 47: 858-863.
    • (2009) Genesis , vol.47 , pp. 858-863
    • Festing, M.H.1    Speer, M.Y.2    Yang, H.-Y.3    Giachelli, C.M.4
  • 92
    • 33947303700 scopus 로고    scopus 로고
    • The vascular biology of calcification
    • Shroff RC, Shanahan CM,. The vascular biology of calcification. Semin Dial 2007; 20: 103-109.
    • (2007) Semin Dial , vol.20 , pp. 103-109
    • Shroff, R.C.1    Shanahan, C.M.2
  • 93
    • 70349576584 scopus 로고    scopus 로고
    • Vascular smooth muscle cell calcification and SLC20 inorganic phosphate transporters: Effects of PDGF, TNF-alpha, and Pi
    • Villa-Bellosta R, Levi M, Sorribas V,. Vascular smooth muscle cell calcification and SLC20 inorganic phosphate transporters: effects of PDGF, TNF-alpha, and Pi. Pflugers Arch-Eur J Physiol 2009; 458: 1151-1161.
    • (2009) Pflugers Arch - Eur J Physiol , vol.458 , pp. 1151-1161
    • Villa-Bellosta, R.1    Levi, M.2    Sorribas, V.3
  • 94
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL,. Osteoclast differentiation and activation. Nature 2003; 423: 337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 96
    • 38449108005 scopus 로고    scopus 로고
    • Regulation of osteoclast differentiation and function by phosphate: Potential role of osteoclasts in the skeletal abnormalities in hypophosphatemic conditions
    • Hayashibara T, Hiraga T, Sugita A, Wang L, Hata K, Ooshima T, Yoneda T,. Regulation of osteoclast differentiation and function by phosphate: potential role of osteoclasts in the skeletal abnormalities in hypophosphatemic conditions. J Bone Miner Res 2007; 22: 1743-1751.
    • (2007) J Bone Miner Res , vol.22 , pp. 1743-1751
    • Hayashibara, T.1    Hiraga, T.2    Sugita, A.3    Wang, L.4    Hata, K.5    Ooshima, T.6    Yoneda, T.7
  • 98
    • 38749126786 scopus 로고    scopus 로고
    • Exploring the biology of vascular calcification in chronic kidney disease: What's circulating?
    • Schoppet M, Shroff RC, Hofbauer LC, Shanahan CM,. Exploring the biology of vascular calcification in chronic kidney disease: what's circulating? Kidney Int 2008; 73: 384-390.
    • (2008) Kidney Int , vol.73 , pp. 384-390
    • Schoppet, M.1    Shroff, R.C.2    Hofbauer, L.C.3    Shanahan, C.M.4
  • 100
    • 0032494113 scopus 로고    scopus 로고
    • TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
    • Fuller K, Wong B, Fox S, Choi Y, Chambers TJ,. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. Isr J Exp Med 1998; 188: 997-1001.
    • (1998) Isr J Exp Med , vol.188 , pp. 997-1001
    • Fuller, K.1    Wong, B.2    Fox, S.3    Choi, Y.4    Chambers, T.J.5
  • 102
    • 33645757920 scopus 로고    scopus 로고
    • Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    • Moe S, Drüeke T, Cunningham J, Goodman W, Martin K, Olgaard K, Ott S, Sprague S, Lameire N, Eknoyan G,. Definition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: improving Global Outcomes (KDIGO). Kidney Int 2006; 69: 1945-1953.
    • (2006) Kidney Int , vol.69 , pp. 1945-1953
    • Moe, S.1    Drüeke, T.2    Cunningham, J.3    Goodman, W.4    Martin, K.5    Olgaard, K.6    Ott, S.7    Sprague, S.8    Lameire, N.9    Eknoyan, G.10
  • 104
    • 0034995079 scopus 로고    scopus 로고
    • Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells
    • Ahmed S, O'Neill KD, Hood AF, Evan AP, Moe SM,. Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells. Am J Kidney Dis 2001; 37: 1267-1276.
    • (2001) Am J Kidney Dis , vol.37 , pp. 1267-1276
    • Ahmed, S.1    O'Neill, K.D.2    Hood, A.F.3    Evan, A.P.4    Moe, S.M.5
  • 105
    • 0042885985 scopus 로고    scopus 로고
    • Arterial media calcification in end-stage renal disease: Impact on all-cause and cardiovascular mortality
    • London GM, Guerin AP, Marchais SJ, Metivier F, Pannier B, Adda H,. Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 2003; 18: 1731-1740.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1731-1740
    • London, G.M.1    Guerin, A.P.2    Marchais, S.J.3    Metivier, F.4    Pannier, B.5    Adda, H.6
  • 106
    • 0035725506 scopus 로고    scopus 로고
    • Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease
    • Blacher J, Guerin AP, Pannier B, Marchais SJ, London GM,. Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease. Hypertension 2001; 38: 938-942.
    • (2001) Hypertension , vol.38 , pp. 938-942
    • Blacher, J.1    Guerin, A.P.2    Pannier, B.3    Marchais, S.J.4    London, G.M.5
  • 107
    • 33947314500 scopus 로고    scopus 로고
    • The functional cardiovascular consequences of vascular calcification
    • McIntyre CW,. The functional cardiovascular consequences of vascular calcification. Semin Dial 2007; 20: 122-128.
    • (2007) Semin Dial , vol.20 , pp. 122-128
    • McIntyre, C.W.1
  • 108
    • 84871721782 scopus 로고    scopus 로고
    • Cardiovascular disease in an adenine-induced model of chronic kidney disease: The temporal link between vascular calcification and haemodynamic consequences
    • Shobeiri N, Pang J, Adams MA, Holden RM,. Cardiovascular disease in an adenine-induced model of chronic kidney disease: the temporal link between vascular calcification and haemodynamic consequences. J Hypertens 2013; 31: 160-168.
    • (2013) J Hypertens , vol.31 , pp. 160-168
    • Shobeiri, N.1    Pang, J.2    Adams, M.A.3    Holden, R.M.4
  • 111
    • 26944445097 scopus 로고    scopus 로고
    • Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: The USRDS waves 1, 3, and 4 study
    • Slinin Y, Foley RN, Collins AJ,. Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: the USRDS waves 1, 3, and 4 study. J Am Soc Nephrol 2005; 16: 1788-1793.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1788-1793
    • Slinin, Y.1    Foley, R.N.2    Collins, A.J.3
  • 112
    • 1542288794 scopus 로고    scopus 로고
    • Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: Evidence for the complexity of the association between mineral metabolism and outcomes
    • Stevens LA,. Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: evidence for the complexity of the association between mineral metabolism and outcomes. J Am Soc Nephrol 2004; 15: 770-779.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 770-779
    • Stevens, L.A.1
  • 114
    • 54149085758 scopus 로고    scopus 로고
    • Prevalence and associations of coronary artery calcification in patients with stages 3 to 5 CKD without cardiovascular disease
    • Garland J, Holden R, Groome P, Lam M, Nolan R, Morton R, Pickett W,. Prevalence and associations of coronary artery calcification in patients with stages 3 to 5 CKD without cardiovascular disease. Am J Kidney Dis 2008; 52: 849-858.
    • (2008) Am J Kidney Dis , vol.52 , pp. 849-858
    • Garland, J.1    Holden, R.2    Groome, P.3    Lam, M.4    Nolan, R.5    Morton, R.6    Pickett, W.7
  • 115
    • 0037138580 scopus 로고    scopus 로고
    • Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease?
    • Raggi P, Boulay A, Chasan-Taber S, Amin N, Dillon M, Burke SK, Chertow GM,. Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease? J Am Coll Cardiol 2002; 39: 695-701.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 695-701
    • Raggi, P.1    Boulay, A.2    Chasan-Taber, S.3    Amin, N.4    Dillon, M.5    Burke, S.K.6    Chertow, G.M.7
  • 116
    • 0036645027 scopus 로고    scopus 로고
    • Advanced coronary and carotid arteriopathy in young adults with childhood-onset chronic renal failure
    • Oh J, Wunsch R, Turzer M, Bahner M, Raggi P, Querfeld U, Mehls O, Schaefer F,. Advanced coronary and carotid arteriopathy in young adults with childhood-onset chronic renal failure. Circulation 2002; 106: 100-105.
    • (2002) Circulation , vol.106 , pp. 100-105
    • Oh, J.1    Wunsch, R.2    Turzer, M.3    Bahner, M.4    Raggi, P.5    Querfeld, U.6    Mehls, O.7    Schaefer, F.8
  • 118
    • 70450230670 scopus 로고    scopus 로고
    • Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
    • Mirza MAI, Larsson A, Melhus H, Lind L, Larsson TE,. Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population. Atherosclerosis 2009; 207: 546-551.
    • (2009) Atherosclerosis , vol.207 , pp. 546-551
    • Mirza, M.A.I.1    Larsson, A.2    Melhus, H.3    Lind, L.4    Larsson, T.E.5
  • 122
    • 84864863897 scopus 로고    scopus 로고
    • Dialysis Outcomes and Practice Patterns Study (DOPPS) (last accessed 27 September 2012)
    • Dialysis Outcomes and Practice Patterns Study (DOPPS). 2010 DOPPS Annual Report [Internet]. Available at http://www.dopps.org/annualreport/index.htm (last accessed 27 September 2012).
    • 2010 DOPPS Annual Report
  • 124
    • 33847223412 scopus 로고    scopus 로고
    • Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients
    • Block GA, Raggi P, Bellasi A, Kooienga L, Spiegel DM,. Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int 2007; 71: 438-441.
    • (2007) Kidney Int , vol.71 , pp. 438-441
    • Block, G.A.1    Raggi, P.2    Bellasi, A.3    Kooienga, L.4    Spiegel, D.M.5
  • 125
    • 84858038439 scopus 로고    scopus 로고
    • Mortality in kidney disease patients treated with phosphate binders: A randomized study
    • Di Iorio B, Bellasi A, Russo D,. Mortality in kidney disease patients treated with phosphate binders: a randomized study. Clin J Am Soc Nephrol. 2012; 7: 487-493.
    • (2012) Clin J Am Soc Nephrol. , vol.7 , pp. 487-493
    • Di Iorio, B.1    Bellasi, A.2    Russo, D.3
  • 127
    • 31644446801 scopus 로고    scopus 로고
    • Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis
    • Block GA, Spiegel DM, Ehrlich J, Mehta R, Lindbergh J, Dreisbach A, Raggi P,. Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis. Kidney Int 2005; 68: 1815-1824.
    • (2005) Kidney Int , vol.68 , pp. 1815-1824
    • Block, G.A.1    Spiegel, D.M.2    Ehrlich, J.3    Mehta, R.4    Lindbergh, J.5    Dreisbach, A.6    Raggi, P.7
  • 128
    • 43849094954 scopus 로고    scopus 로고
    • A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: The Calcium Acetate Renagel Evaluation-2 (CARE-2) study
    • Qunibi W, Moustafa M, Muenz LR, He DY, Kessler PD, Diaz-Buxo JA, Budoff M,. A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: the Calcium Acetate Renagel Evaluation-2 (CARE-2) study. Am J Kidney Dis 2008; 51: 952-965.
    • (2008) Am J Kidney Dis , vol.51 , pp. 952-965
    • Qunibi, W.1    Moustafa, M.2    Muenz, L.R.3    He, D.Y.4    Kessler, P.D.5    Diaz-Buxo, J.A.6    Budoff, M.7
  • 129
    • 0036310682 scopus 로고    scopus 로고
    • Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients
    • Chertow GM, Burke SK, Raggi P,. Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. Kidney Int 2002; 62: 245-252.
    • (2002) Kidney Int , vol.62 , pp. 245-252
    • Chertow, G.M.1    Burke, S.K.2    Raggi, P.3
  • 132
    • 77955129195 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)
    • Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group
    • Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int 2009; 76: S50-99.
    • (2009) Kidney Int , vol.76
  • 134
    • 0036707883 scopus 로고    scopus 로고
    • The effects of sevelamer hydrochloride and calcium carbonate on kidney calcification in uremic rats
    • Cozzolino M,. The effects of sevelamer hydrochloride and calcium carbonate on kidney calcification in uremic rats. J Am Soc Nephrol 2002; 13: 2299-2308.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2299-2308
    • Cozzolino, M.1
  • 135
    • 77951033351 scopus 로고    scopus 로고
    • Vascular calcification in animal models of CKD: A review
    • Shobeiri N, Adams MA, Holden RM, Adams A,. Vascular calcification in animal models of CKD: a review. Am J Nephrol 2010; 31: 471-481.
    • (2010) Am J Nephrol , vol.31 , pp. 471-481
    • Shobeiri, N.1    Adams, M.A.2    Holden, R.M.3    Adams, A.4
  • 136
    • 33845982605 scopus 로고    scopus 로고
    • A. Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy
    • Mathew S, Lund RJ, Strebeck F, Tustison KS, Geurs T, Hruska K,. a. Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy. J Am Soc Nephrol 2007; 18: 122-130.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 122-130
    • Mathew, S.1    Lund, R.J.2    Strebeck, F.3    Tustison, K.S.4    Geurs, T.5    Hruska, K.6
  • 137
    • 0038458791 scopus 로고    scopus 로고
    • Sevelamer hydrochloride prevents ectopic calcification and renal osteodystrophy in chronic renal failure rats
    • Katsumata K, Kusano K, Hirata M, Tsunemi K, Nagano N, Burke SK, Fukushima N,. Sevelamer hydrochloride prevents ectopic calcification and renal osteodystrophy in chronic renal failure rats. Kidney Int 2003; 64: 441-450.
    • (2003) Kidney Int , vol.64 , pp. 441-450
    • Katsumata, K.1    Kusano, K.2    Hirata, M.3    Tsunemi, K.4    Nagano, N.5    Burke, S.K.6    Fukushima, N.7
  • 139
    • 20844462829 scopus 로고    scopus 로고
    • A. Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome
    • Davies MR, Lund RJ, Mathew S, Hruska K,. a. Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome. J Am Soc Nephrol 2005; 16: 917-928.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 917-928
    • Davies, M.R.1    Lund, R.J.2    Mathew, S.3    Hruska, K.4
  • 140
    • 79951977919 scopus 로고    scopus 로고
    • Pharmacology of the phosphate binder, lanthanum carbonate
    • Damment SJP,. Pharmacology of the phosphate binder, lanthanum carbonate. Ren Fail 2011; 33: 217-224.
    • (2011) Ren Fail , vol.33 , pp. 217-224
    • Damment, S.J.P.1
  • 141
    • 79958123458 scopus 로고    scopus 로고
    • Long-term treatment with lanthanum carbonate reduces mineral and bone abnormalities in rats with chronic renal failure
    • Damment S, Secker R, Shen V, Lorenzo V, Rodriguez M,. Long-term treatment with lanthanum carbonate reduces mineral and bone abnormalities in rats with chronic renal failure. Nephrol Dial Transplant 2011; 26: 1803-1812.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 1803-1812
    • Damment, S.1    Secker, R.2    Shen, V.3    Lorenzo, V.4    Rodriguez, M.5
  • 144
    • 34548274602 scopus 로고    scopus 로고
    • Differential effects of vitamin D analogs on vascular calcification
    • Panizo S, Parisi E, Fernandez E, Valdivielso JM,. Differential effects of vitamin D analogs on vascular calcification. J Bone Miner Res 2007; 22: 860-866.
    • (2007) J Bone Miner Res , vol.22 , pp. 860-866
    • Panizo, S.1    Parisi, E.2    Fernandez, E.3    Valdivielso, J.M.4
  • 146
    • 58049199370 scopus 로고    scopus 로고
    • A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia
    • Koleganova N, Piecha G, Ritz E, Schmitt CP, Gross M-L,. A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia. Kidney Int 2009; 75: 60-71.
    • (2009) Kidney Int , vol.75 , pp. 60-71
    • Koleganova, N.1    Piecha, G.2    Ritz, E.3    Schmitt, C.P.4    Gross, M.-L.5
  • 152
    • 33748656065 scopus 로고    scopus 로고
    • Pharmacological activity of calcimimetic NPS R-568 administered intravenously in rats?: Dose dependency
    • Rybczyñska A, Boblewski K, Lehmann A, Orlewska C, Foks H,. Pharmacological activity of calcimimetic NPS R-568 administered intravenously in rats?: dose dependency. Pharmacol Rep 2006; 52: 533-539.
    • (2006) Pharmacol Rep , vol.52 , pp. 533-539
    • Rybczyñska, A.1    Boblewski, K.2    Lehmann, A.3    Orlewska, C.4    Foks, H.5
  • 160
    • 0025091788 scopus 로고
    • Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro
    • Carano A, Teitelbaum SL, Konsek JD, Schlesinger PH, Blair HC,. Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro. J Clin Invest 1990; 85: 456-461.
    • (1990) J Clin Invest , vol.85 , pp. 456-461
    • Carano, A.1    Teitelbaum, S.L.2    Konsek, J.D.3    Schlesinger, P.H.4    Blair, H.C.5
  • 161
    • 0029884643 scopus 로고    scopus 로고
    • Bisphosphonates: Mechanisms of action
    • Rodan GA, Fleisch HA,. Bisphosphonates: mechanisms of action. J Clin Invest 1996; 97: 2692-2696.
    • (1996) J Clin Invest , vol.97 , pp. 2692-2696
    • Rodan, G.A.1    Fleisch, H.A.2
  • 162
    • 15944429695 scopus 로고    scopus 로고
    • Long-term safety of bisphosphonates
    • Ott SM,. Long-term safety of bisphosphonates. J Clin Endocrinol Metab 2005; 90: 1897-1899.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1897-1899
    • Ott, S.M.1
  • 164
    • 33750220360 scopus 로고    scopus 로고
    • Artery calcification in uremic rats is increased by a low protein diet and prevented by treatment with ibandronate
    • Price PA, Roublick AM, Williamson MK,. Artery calcification in uremic rats is increased by a low protein diet and prevented by treatment with ibandronate. Kidney Int 2006; 70: 1577-1583.
    • (2006) Kidney Int , vol.70 , pp. 1577-1583
    • Price, P.A.1    Roublick, A.M.2    Williamson, M.K.3
  • 165
    • 3142654694 scopus 로고    scopus 로고
    • Inhibitory effects of etidronate on the progression of vascular calcification in hemodialysis patients
    • Hashiba H, Aizawa S, Tamura K, Shigematsu T, Kogo H,. Inhibitory effects of etidronate on the progression of vascular calcification in hemodialysis patients. Ther Apher Dial 2004; 8: 241-247.
    • (2004) Ther Apher Dial , vol.8 , pp. 241-247
    • Hashiba, H.1    Aizawa, S.2    Tamura, K.3    Shigematsu, T.4    Kogo, H.5
  • 166
    • 4544291461 scopus 로고    scopus 로고
    • Effects of cyclic intermittent etidronate therapy on coronary artery calcification in patients receiving long-term hemodialysis
    • Nitta K, Akiba T, Suzuki K, Uchida K, Watanabe R-I, Majima K, Aoki T, Nihei H,. Effects of cyclic intermittent etidronate therapy on coronary artery calcification in patients receiving long-term hemodialysis. Am J Kidney Dis 2004; 44: 680-688.
    • (2004) Am J Kidney Dis , vol.44 , pp. 680-688
    • Nitta, K.1    Akiba, T.2    Suzuki, K.3    Uchida, K.4    Watanabe, R.-I.5    Majima, K.6    Aoki, T.7    Nihei, H.8
  • 170
    • 34748904679 scopus 로고    scopus 로고
    • Vascular calcification in chronic kidney disease: The role of vitamin K
    • Holden RM, Booth SL,. Vascular calcification in chronic kidney disease: the role of vitamin K. Nat Clin Pract Nephrol 2007; 3: 522-523.
    • (2007) Nat Clin Pract Nephrol , vol.3 , pp. 522-523
    • Holden, R.M.1    Booth, S.L.2
  • 172
    • 22744434737 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in vascular calcification
    • Hruska KA, Mathew S, Saab G,. Bone morphogenetic proteins in vascular calcification. Circ Res 2005; 97: 105-114.
    • (2005) Circ Res , vol.97 , pp. 105-114
    • Hruska, K.A.1    Mathew, S.2    Saab, G.3
  • 173
    • 0037835949 scopus 로고    scopus 로고
    • BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure
    • Davies MR,. BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. J Am Soc Nephrol 2003; 14: 1559-1567.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1559-1567
    • Davies, M.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.