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Volumn 58, Issue 4, 2006, Pages 533-539

Pharmacological activity of calcimimetic NPS R-568 administered intravenously in rats: Dose dependency

Author keywords

Blood pressure; Calcimimetics; Parathormone; Parathyroid hypertensive factor; Pharmacological parathyroidectomy

Indexed keywords

CALCIMIMETIC AGENT; CALCIUM ION; INULIN; N [3 (2 CHLOROPHENYL)PROPYL] 1 (3 METHOXYPHENYL)ETHYLAMINE; PHOSPHATE; SODIUM CHLORIDE; THIOPENTAL; TRITIUM;

EID: 33748656065     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (21)
  • 1
    • 0031888842 scopus 로고    scopus 로고
    • A calcimimetic agent acutely suspresses parathyroid hormone levels in patients with chronic renal failure
    • Antonsen JE, Sherrard DJ, Andress DL: A calcimimetic agent acutely suspresses parathyroid hormone levels in patients with chronic renal failure. Kidney Int, 1998, 53, 223-227.
    • (1998) Kidney Int , vol.53 , pp. 223-227
    • Antonsen, J.E.1    Sherrard, D.J.2    Andress, D.L.3
  • 3
    • 0034012178 scopus 로고    scopus 로고
    • Activation of the calcium receptor by the calcimimetics halts progression of secondary hyperparathyroidism in uremic rats
    • Chin JI, Miller SC, Wada M, Nagano N, Nemeth EF, Fox J: Activation of the calcium receptor by the calcimimetics halts progression of secondary hyperparathyroidism in uremic rats. J Am Soc Nephrol, 2000, 11, 903-911.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 903-911
    • Chin, J.I.1    Miller, S.C.2    Wada, M.3    Nagano, N.4    Nemeth, E.F.5    Fox, J.6
  • 4
    • 0000154206 scopus 로고
    • The colorimetric determination of phosphorus
    • Fiske CH and SubbaRow Y: The colorimetric determination of phosphorus. J Biol Chem, 1925, 66, 375-400.
    • (1925) J Biol Chem , vol.66 , pp. 375-400
    • Fiske, C.H.1    SubbaRow, Y.2
  • 5
    • 0032808078 scopus 로고    scopus 로고
    • NPS R-568: A type II calcimimetic compound that acts on parathyroid cell calcium receptor of rats to reduce plasma levels of parathyroid hormone and calcium
    • Fox J, Lowe SH, Petty BA, Nemeth EF: NPS R-568: a type II calcimimetic compound that acts on parathyroid cell calcium receptor of rats to reduce plasma levels of parathyroid hormone and calcium. J Pharmacol Exp Ther, 1999, 290, 473-479.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 473-479
    • Fox, J.1    Lowe, S.H.2    Petty, B.A.3    Nemeth, E.F.4
  • 6
    • 0033935152 scopus 로고    scopus 로고
    • A calcimimetic agent lowers plasma parathyroid hormone levels in patients with secondary hyperparathyroidism
    • Goodman WG, Frazao JM, Goodkin DA, Turner GS, Liu W, Coburn JW: A calcimimetic agent lowers plasma parathyroid hormone levels in patients with secondary hyperparathyroidism. Kidney Int, 2000, 58, 436-445.
    • (2000) Kidney Int , vol.58 , pp. 436-445
    • Goodman, W.G.1    Frazao, J.M.2    Goodkin, D.A.3    Turner, G.S.4    Liu, W.5    Coburn, J.W.6
  • 7
    • 0036208986 scopus 로고    scopus 로고
    • The calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism
    • Goodman WG, Hladik DA, Turner SA, Blaisdell PW, Goodkin DA, Liu W, Bari YM et al.: The calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol, 2002, 13, 1017-1024.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1017-1024
    • Goodman, W.G.1    Hladik, D.A.2    Turner, S.A.3    Blaisdell, P.W.4    Goodkin, D.A.5    Liu, W.6    Bari, Y.M.7
  • 9
    • 0024533057 scopus 로고
    • Effects of spontaneously hypertensive rat plasma on blood pressure and tail artery calcium uptake in normotensive rats
    • Lewanczuk RZ, Wang J, Zhang ZR, Pang KT: Effects of spontaneously hypertensive rat plasma on blood pressure and tail artery calcium uptake in normotensive rats. Am J Hypertens, 1989, 2, 26-31.
    • (1989) Am J Hypertens , vol.2 , pp. 26-31
    • Lewanczuk, R.Z.1    Wang, J.2    Zhang, Z.R.3    Pang, K.T.4
  • 10
    • 0034503366 scopus 로고    scopus 로고
    • Pharmacological properties of the calcimimetic compound NPS R-568 in vitro and in vivo
    • Mukarami Y, Furuya Y, Wada M, Sakai T, Nagano N: Pharmacological properties of the calcimimetic compound NPS R-568 in vitro and in vivo. Clin Exp Nephrol, 2000, 4, 293-299.
    • (2000) Clin Exp Nephrol , vol.4 , pp. 293-299
    • Mukarami, Y.1    Furuya, Y.2    Wada, M.3    Sakai, T.4    Nagano, N.5
  • 11
    • 0031850886 scopus 로고    scopus 로고
    • Tricking the parathyroid glands with novel calcimimetric agents
    • Nemeth EF, Bennet SA: Tricking the parathyroid glands with novel calcimimetric agents. Nephrol Dial Transplant, 1999, 13, 1923-1925.
    • (1999) Nephrol Dial Transplant , vol.13 , pp. 1923-1925
    • Nemeth, E.F.1    Bennet, S.A.2
  • 12
    • 0037378029 scopus 로고    scopus 로고
    • Beneficial effects of calcimimetics on progression of renal failure and cardiovascular risk factors
    • Ogata H, Ritz E, Odoni G, Amann K, Orth SR: Beneficial effects of calcimimetics on progression of renal failure and cardiovascular risk factors. J Am Soc Nephrol, 2003, 14, 959-967.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 959-967
    • Ogata, H.1    Ritz, E.2    Odoni, G.3    Amann, K.4    Orth, S.R.5
  • 13
    • 0027966468 scopus 로고
    • Phosphaturic effect of parathyroids hormone in the spontaneously hypertensive rats
    • Onsgaard-Meyer MJ, Berndt TJ, Khraibi AA, Knox FG: Phosphaturic effect of parathyroids hormone in the spontaneously hypertensive rats. Am J Physiol, 1994, 267, R78-R83.
    • (1994) Am J Physiol , vol.267
    • Onsgaard-Meyer, M.J.1    Berndt, T.J.2    Khraibi, A.A.3    Knox, F.G.4
  • 14
    • 45949119372 scopus 로고
    • 1H-NMR assay of the enantiomeric composition of amines and β-amino alkohols using O-acetyl mandelic acid as a chiral solvating agent
    • 1H-NMR assay of the enantiomeric composition of amines and β-amino alkohols using O-acetyl mandelic acid as a chiral solvating agent. Tetrahedron, 1987, 43, 5451-5456.
    • (1987) Tetrahedron , vol.43 , pp. 5451-5456
    • Parker, D.1    Taylor, R.J.2
  • 15
    • 2342597749 scopus 로고    scopus 로고
    • Effect of the calcimimetic NPS R-467 on furosemide-induced nephrocalcinosis in the young rat
    • Pattaragam A, Fox J, Alon US: Effect of the calcimimetic NPS R-467 on furosemide-induced nephrocalcinosis in the young rat. Kidney Int, 2004, 65, 1684-1689.
    • (2004) Kidney Int , vol.65 , pp. 1684-1689
    • Pattaragam, A.1    Fox, J.2    Alon, U.S.3
  • 16
    • 0025139726 scopus 로고
    • Propranolol restores phosphaturic effect of PTH in short-term phosphate deprivation
    • Rybczyńska A, Hoppe A, Knox FG: Propranolol restores phosphaturic effect of PTH in short-term phosphate deprivation. Am J Physiol, 1990, 258, R120-R123.
    • (1990) Am J Physiol , vol.258
    • Rybczyńska, A.1    Hoppe, A.2    Knox, F.G.3
  • 17
    • 0030667380 scopus 로고    scopus 로고
    • Short-term inhibition of parathyroid hormone secretion by a calcium receptor agonist in patients with primary hyperparathyroidism
    • Silverberg SJ, Bone III HG, Mariott TB, Locker FG, Thys-Jacobs S, Dziem G et al.: Short-term inhibition of parathyroid hormone secretion by a calcium receptor agonist in patients with primary hyperparathyroidism. N Engl J Med, 1997, 337, 1506-1510.
    • (1997) N Engl J Med , vol.337 , pp. 1506-1510
    • Silverberg, S.J.1    Bone III, H.G.2    Mariott, T.B.3    Locker, F.G.4    Thys-Jacobs, S.5    Dziem, G.6
  • 18
    • 1442323838 scopus 로고    scopus 로고
    • Regulation of parathyroid hypertensive factor secretion by Ca2+ in spontaneously hypertensive rat parathyroid cells
    • Sutherland SK, Benishin CG: Regulation of parathyroid hypertensive factor secretion by Ca2+ in spontaneously hypertensive rat parathyroid cells. Am J Hypertens, 2004, 17, 266-272.
    • (2004) Am J Hypertens , vol.17 , pp. 266-272
    • Sutherland, S.K.1    Benishin, C.G.2
  • 20
    • 0033998869 scopus 로고    scopus 로고
    • Calcimimetic NPS R-568 prevents parathyroid hyperplasia in rats with severe secondary hyperparathyroidism
    • Wada M, Nagano N, Furuya Y, Chin J, Nemeth EF, Fox J: Calcimimetic NPS R-568 prevents parathyroid hyperplasia in rats with severe secondary hyperparathyroidism. Kidney Int, 2000, 57, 50-58.
    • (2000) Kidney Int , vol.57 , pp. 50-58
    • Wada, M.1    Nagano, N.2    Furuya, Y.3    Chin, J.4    Nemeth, E.F.5    Fox, J.6
  • 21
    • 0035939471 scopus 로고    scopus 로고
    • Nucleophilic addition of methyllithium to chiral oxime ethers: Asymmetric preparation of 1-(aryl)ethylamines and application to a synthesis of calcimimetics (+)-NPS R-568 and its thio analog
    • Yamazaki N, Atobe M, Kibayashi C: Nucleophilic addition of methyllithium to chiral oxime ethers: asymmetric preparation of 1-(aryl)ethylamines and application to a synthesis of calcimimetics (+)-NPS R-568 and its thio analog. Tetrahedron Lett, 2001, 42, 5029-5032.
    • (2001) Tetrahedron Lett , vol.42 , pp. 5029-5032
    • Yamazaki, N.1    Atobe, M.2    Kibayashi, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.