-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
4
-
-
77957859044
-
Modeling core metabolism in cancer cells: surveying the topology underlying the Warburg effect
-
Resendis-Antonio O., Checa A., Encarnación S. Modeling core metabolism in cancer cells: surveying the topology underlying the Warburg effect. PLoS ONE 2010, 5:1-11.
-
(2010)
PLoS ONE
, vol.5
, pp. 1-11
-
-
Resendis-Antonio, O.1
Checa, A.2
Encarnación, S.3
-
5
-
-
79953661070
-
Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect
-
Shlomi T., Benyamini T., Gottlieb E., Sharan R., Ruppin E. Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect. PLoS Computational Biology 2011, 7:1-8.
-
(2011)
PLoS Computational Biology
, vol.7
, pp. 1-8
-
-
Shlomi, T.1
Benyamini, T.2
Gottlieb, E.3
Sharan, R.4
Ruppin, E.5
-
6
-
-
77951803596
-
Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited
-
Vazquez A., Liu J., Zhou Y., Oltvai Z.N. Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited. BMC Systems Biology 2010, 4:1-9.
-
(2010)
BMC Systems Biology
, vol.4
, pp. 1-9
-
-
Vazquez, A.1
Liu, J.2
Zhou, Y.3
Oltvai, Z.N.4
-
7
-
-
43749083041
-
Brick by brick: metabolism and tumor cell growth
-
DeBerardinis R.J., Sayed N., Ditsworth D., Thompson C.B. Brick by brick: metabolism and tumor cell growth. Current Opinion in Genetics and Development 2008, 18:54-61.
-
(2008)
Current Opinion in Genetics and Development
, vol.18
, pp. 54-61
-
-
DeBerardinis, R.J.1
Sayed, N.2
Ditsworth, D.3
Thompson, C.B.4
-
8
-
-
37449034854
-
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis R.J., Mancuso A., Daikhin E., Nissim I., Yudkoff M., Wehrli S., et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:19345-19350.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 19345-19350
-
-
DeBerardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
-
9
-
-
57749088701
-
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
Wise D.R., DeBerardinis R.J., Mancuso A., Sayed N., Zhang X.Y., Pfeiffer H.K., et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:18782-18787.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 18782-18787
-
-
Wise, D.R.1
DeBerardinis, R.J.2
Mancuso, A.3
Sayed, N.4
Zhang, X.Y.5
Pfeiffer, H.K.6
-
10
-
-
77952836390
-
PathWave: discovering patterns of differentially regulated enzymes in metabolic pathways
-
Schramm G., Wiesberg S., Diessl N., Kranz A.L., Sagulenko V., Oswald M., et al. PathWave: discovering patterns of differentially regulated enzymes in metabolic pathways. Bioinformatics 2010, 26:1225-1231.
-
(2010)
Bioinformatics
, vol.26
, pp. 1225-1231
-
-
Schramm, G.1
Wiesberg, S.2
Diessl, N.3
Kranz, A.L.4
Sagulenko, V.5
Oswald, M.6
-
11
-
-
84880291912
-
BCAT1 promotes cell proliferation via amino acid catabolism in IDH1 wildtype gliomas
-
(in press)
-
Tönjes M., Barbus S., Park Y.J., Wang W., Schlotter M., Lindroth A.M., et al. BCAT1 promotes cell proliferation via amino acid catabolism in IDH1 wildtype gliomas. Nature Medicine 2013, (in press).
-
(2013)
Nature Medicine
-
-
Tönjes, M.1
Barbus, S.2
Park, Y.J.3
Wang, W.4
Schlotter, M.5
Lindroth, A.M.6
-
12
-
-
74949089659
-
Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
-
Samudio I., Harmancey R., Fiegl M., Kantarjian H., Konopleva M., Korchin B., et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. Journal of Clinical Investigation 2010, 120:142-156.
-
(2010)
Journal of Clinical Investigation
, vol.120
, pp. 142-156
-
-
Samudio, I.1
Harmancey, R.2
Fiegl, M.3
Kantarjian, H.4
Konopleva, M.5
Korchin, B.6
-
13
-
-
77956461211
-
Analyzing the regulation of metabolic pathways in human breast cancer
-
Schramm G., Surmann E.M., Wiesberg S., Oswald M., Reinelt G., Eils R., et al. Analyzing the regulation of metabolic pathways in human breast cancer. BMC Medical Genomics 2010, 3:1-10.
-
(2010)
BMC Medical Genomics
, vol.3
, pp. 1-10
-
-
Schramm, G.1
Surmann, E.M.2
Wiesberg, S.3
Oswald, M.4
Reinelt, G.5
Eils, R.6
-
14
-
-
77957656146
-
MiR-378* mediates metabolic shift in breast cancer cells via the PGC-1beta/ERRgamma transcriptional pathway
-
Eichner L.J., Perry M.C., Dufour C.R., Bertos N., Park M., St-Pierre J., et al. miR-378* mediates metabolic shift in breast cancer cells via the PGC-1beta/ERRgamma transcriptional pathway. Cell Metabolism 2010, 12:352-361.
-
(2010)
Cell Metabolism
, vol.12
, pp. 352-361
-
-
Eichner, L.J.1
Perry, M.C.2
Dufour, C.R.3
Bertos, N.4
Park, M.5
St-Pierre, J.6
-
15
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad K., Tsuruta A., Selak M.A., Vidal M.N., Nakano K., Bartrons R., et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 2006, 126:107-120.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
-
16
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
Matoba S., Kang J.G., Patino W.D., Wragg A., Boehm M., Gavrilova O., et al. p53 regulates mitochondrial respiration. Science 2006, 312:1650-1653.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
-
18
-
-
77649094375
-
Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol
-
Zhou M., Zhao Y., Ding Y., Liu H., Liu Z., Fodstad O., et al. Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol. Molecular Cancer 2010, 9:1-12.
-
(2010)
Molecular Cancer
, vol.9
, pp. 1-12
-
-
Zhou, M.1
Zhao, Y.2
Ding, Y.3
Liu, H.4
Liu, Z.5
Fodstad, O.6
-
19
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi Y., Naiman S., Amir G., Peshti V., Zinman G., Nahum L., et al. The sirtuin SIRT6 regulates lifespan in male mice. Nature 2012, 483:218-221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
-
20
-
-
84870874690
-
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism
-
Sebastián C., Zwaans B.M., Silberman D.M., Gymrek M., Goren A., Zhong L., et al. The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell 2012, 151:1185-1199.
-
(2012)
Cell
, vol.151
, pp. 1185-1199
-
-
Sebastián, C.1
Zwaans, B.M.2
Silberman, D.M.3
Gymrek, M.4
Goren, A.5
Zhong, L.6
-
21
-
-
77955077532
-
Identifying essential genes in bacterial metabolic networks with machine learning methods
-
Plaimas K., Eils R., König R. Identifying essential genes in bacterial metabolic networks with machine learning methods. BMC Systems Biology 2010, 4:1-16.
-
(2010)
BMC Systems Biology
, vol.4
, pp. 1-16
-
-
Plaimas, K.1
Eils, R.2
König, R.3
-
22
-
-
79957473580
-
Path finding methods accounting for stoichiometry in metabolic networks
-
Pey J., Prada J., Beasley J.E., Planes F.J. Path finding methods accounting for stoichiometry in metabolic networks. Genome Biology 2011, 12:1-14.
-
(2011)
Genome Biology
, vol.12
, pp. 1-14
-
-
Pey, J.1
Prada, J.2
Beasley, J.E.3
Planes, F.J.4
-
23
-
-
84881102877
-
Cellular systems biology
-
Wiley Blackwell, Weinheim, M. Wink (Ed.)
-
Schmidt-Gienewinkel H., Legewie S., Brors B., König R. Cellular systems biology. An introduction to molecular biotechnology 2011, 295-309. Wiley Blackwell, Weinheim. M. Wink (Ed.).
-
(2011)
An introduction to molecular biotechnology
, pp. 295-309
-
-
Schmidt-Gienewinkel, H.1
Legewie, S.2
Brors, B.3
König, R.4
-
24
-
-
77951612556
-
BiGG: a biochemical genetic and genomic knowledgebase of large scale metabolic reconstructions
-
Schellenberger J., Park J.O., Conrad T.M., Palsson B.Ø. BiGG: a biochemical genetic and genomic knowledgebase of large scale metabolic reconstructions. BMC Bioinformatics 2010, 11:1-10.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 1-10
-
-
Schellenberger, J.1
Park, J.O.2
Conrad, T.M.3
Palsson, B.Ø.4
-
25
-
-
14844326483
-
Computational prediction of human metabolic pathways from the complete human genome
-
Romero P., Wagg J., Green M.L., Kaiser D., Krummenacker M., Karp P.D. Computational prediction of human metabolic pathways from the complete human genome. Genome Biology 2005, 6:R2.1-R2.17.
-
(2005)
Genome Biology
, vol.6
-
-
Romero, P.1
Wagg, J.2
Green, M.L.3
Kaiser, D.4
Krummenacker, M.5
Karp, P.D.6
-
26
-
-
0033982936
-
KEGG: Kyoto Encyclopedia of genes and genomes
-
Kanehisa M., Goto S. KEGG: Kyoto Encyclopedia of genes and genomes. Nucleic Acids Research 2000, 28:27-30.
-
(2000)
Nucleic Acids Research
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
27
-
-
0002386913
-
On the interpretation of ?2 from contingency tables, and the calculation of P.
-
Fisher R.A. On the interpretation of ?2 from contingency tables, and the calculation of P. Journal of the Royal Statistical Society 1922, 85:87-94.
-
(1922)
Journal of the Royal Statistical Society
, vol.85
, pp. 87-94
-
-
Fisher, R.A.1
-
28
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A., Tamayo P., Mootha V.K., Mukherjee S., Ebert B.L., Gillette M.A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:15545-15550.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
-
30
-
-
0027677864
-
Texture analysis and classification with tree-structured wavelet transform
-
Chang T., Kuo C.-C. Texture analysis and classification with tree-structured wavelet transform. IEEE Transactions on Image Processing 1993, 2:429-441.
-
(1993)
IEEE Transactions on Image Processing
, vol.2
, pp. 429-441
-
-
Chang, T.1
Kuo, C.-C.2
-
32
-
-
0034609791
-
The large-scale organization of metabolic networks
-
Jeong H., Tombor B., Albert R., Oltvai Z.N., Barabasi A.L. The large-scale organization of metabolic networks. Nature 2000, 407:651-654.
-
(2000)
Nature
, vol.407
, pp. 651-654
-
-
Jeong, H.1
Tombor, B.2
Albert, R.3
Oltvai, Z.N.4
Barabasi, A.L.5
-
33
-
-
78650002545
-
Large-scale in silico modeling of metabolic interactions between cell types in the human brain
-
Lewis N.E., Schramm G., Bordbar A., Schellenberger J., Andersen M.P., Cheng J.K., et al. Large-scale in silico modeling of metabolic interactions between cell types in the human brain. Nature Biotechnology 2010, 28:1279-1285.
-
(2010)
Nature Biotechnology
, vol.28
, pp. 1279-1285
-
-
Lewis, N.E.1
Schramm, G.2
Bordbar, A.3
Schellenberger, J.4
Andersen, M.P.5
Cheng, J.K.6
-
35
-
-
75149129569
-
A protocol for generating a high-quality genome-scale metabolic reconstruction
-
Thiele I., Palsson B.Ø. A protocol for generating a high-quality genome-scale metabolic reconstruction. Nature Protocols 2010, 5:93-121.
-
(2010)
Nature Protocols
, vol.5
, pp. 93-121
-
-
Thiele, I.1
Palsson, B.Ø.2
-
36
-
-
77953934646
-
BioModels database: an enhanced, curated and annotated resource for published quantitative kinetic models
-
Li C., Donizelli M., Rodriguez N., Dharuri H., Endler L., Chelliah V., et al. BioModels database: an enhanced, curated and annotated resource for published quantitative kinetic models. BMC Systems Biology 2010, 4:1-14.
-
(2010)
BMC Systems Biology
, vol.4
, pp. 1-14
-
-
Li, C.1
Donizelli, M.2
Rodriguez, N.3
Dharuri, H.4
Endler, L.5
Chelliah, V.6
-
37
-
-
25644458211
-
The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes
-
Overbeek R., Begley T., Butler R.M., Choudhuri J.V., Chuang H.Y., Cohoon M., et al. The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes. Nucleic Acids Research 2005, 33:5691-5702.
-
(2005)
Nucleic Acids Research
, vol.33
, pp. 5691-5702
-
-
Overbeek, R.1
Begley, T.2
Butler, R.M.3
Choudhuri, J.V.4
Chuang, H.Y.5
Cohoon, M.6
-
38
-
-
84877315835
-
A community-driven global reconstruction of human metabolism
-
Thiele I., Swainston N., Fleming R.M., Hoppe A., Sahoo S., Aurich M.K., et al. A community-driven global reconstruction of human metabolism. Nature Biotechnology 2013, 31:419-425.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 419-425
-
-
Thiele, I.1
Swainston, N.2
Fleming, R.M.3
Hoppe, A.4
Sahoo, S.5
Aurich, M.K.6
-
39
-
-
77956417789
-
Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
-
Jerby L., Shlomi T., Ruppin E. Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism. Molecular Systems Biology 2010, 6:1-9.
-
(2010)
Molecular Systems Biology
, vol.6
, pp. 1-9
-
-
Jerby, L.1
Shlomi, T.2
Ruppin, E.3
-
40
-
-
44949225040
-
Context-specific metabolic networks are consistent with experiments
-
Becker S.A., Palsson B.O. Context-specific metabolic networks are consistent with experiments. PLoS Computational Biology 2008, 4:1-10.
-
(2008)
PLoS Computational Biology
, vol.4
, pp. 1-10
-
-
Becker, S.A.1
Palsson, B.O.2
-
41
-
-
84863662483
-
Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT
-
Agren R., Bordel S., Mardinoglu A., Pornputtapong N., Nookaew I., Nielsen J. Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. PLoS Computational Biology 2012, 8:1-9.
-
(2012)
PLoS Computational Biology
, vol.8
, pp. 1-9
-
-
Agren, R.1
Bordel, S.2
Mardinoglu, A.3
Pornputtapong, N.4
Nookaew, I.5
Nielsen, J.6
-
42
-
-
84870933131
-
Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
-
Wang Y., Eddy J.A., Price N.D. Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE. BMC Systems Biology 2012, 6:1-16.
-
(2012)
BMC Systems Biology
, vol.6
, pp. 1-16
-
-
Wang, Y.1
Eddy, J.A.2
Price, N.D.3
-
43
-
-
79551662521
-
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2. 0
-
Schellenberger J., Que R., Fleming R.M., Thiele I., Orth J.D., Feist A.M., et al. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2. 0. Nature Protocols 2011, 6:1290-1307.
-
(2011)
Nature Protocols
, vol.6
, pp. 1290-1307
-
-
Schellenberger, J.1
Que, R.2
Fleming, R.M.3
Thiele, I.4
Orth, J.D.5
Feist, A.M.6
-
44
-
-
33845368513
-
COPASI - a COmplex PAthway SImulator
-
Hoops S., Sahle S., Gauges R., Lee C., Pahle J., Simus N., et al. COPASI - a COmplex PAthway SImulator. Bioinformatics 2006, 22:3067-3074.
-
(2006)
Bioinformatics
, vol.22
, pp. 3067-3074
-
-
Hoops, S.1
Sahle, S.2
Gauges, R.3
Lee, C.4
Pahle, J.5
Simus, N.6
-
45
-
-
34447551397
-
Structural and functional analysis of cellular networks with CellNetAnalyzer
-
Klamt S., Saez-Rodriguez J., Gilles E.D. Structural and functional analysis of cellular networks with CellNetAnalyzer. BMC Systems Biology 2007, 1:1-13.
-
(2007)
BMC Systems Biology
, vol.1
, pp. 1-13
-
-
Klamt, S.1
Saez-Rodriguez, J.2
Gilles, E.D.3
-
46
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols 2009, 4:44-57.
-
(2009)
Nature Protocols
, vol.4
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
47
-
-
0034741985
-
A universal framework for 13C metabolic flux analysis
-
Wiechert W., Möllney M., Petersen S., de Graaf A.A. A universal framework for 13C metabolic flux analysis. Metabolic Engineering 2001, 3:265-283.
-
(2001)
Metabolic Engineering
, vol.3
, pp. 265-283
-
-
Wiechert, W.1
Möllney, M.2
Petersen, S.3
de Graaf, A.A.4
-
48
-
-
25444489844
-
FiatFlux - a software for metabolic flux analysis from 13C-glucose experiments
-
Zamboni N., Fischer E., Sauer U. FiatFlux - a software for metabolic flux analysis from 13C-glucose experiments. BMC Bioinformatics 2005, 6:1-8.
-
(2005)
BMC Bioinformatics
, vol.6
, pp. 1-8
-
-
Zamboni, N.1
Fischer, E.2
Sauer, U.3
-
49
-
-
80053175304
-
TIGER: toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks
-
Jensen P.A., Lutz K.A., Papin J.A. TIGER: toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks. BMC Systems Biology 2011, 5:1-12.
-
(2011)
BMC Systems Biology
, vol.5
, pp. 1-12
-
-
Jensen, P.A.1
Lutz, K.A.2
Papin, J.A.3
-
50
-
-
9444266171
-
CellDesigner: a process diagram editor for gene-regulatory and biochemical networks
-
Funahashi A., Tanimura N., Morohashi M., Kitano H. CellDesigner: a process diagram editor for gene-regulatory and biochemical networks. BIOSILICO 2003, 1:159-162.
-
(2003)
BIOSILICO
, vol.1
, pp. 159-162
-
-
Funahashi, A.1
Tanimura, N.2
Morohashi, M.3
Kitano, H.4
-
51
-
-
79960342167
-
Visualizing multi-omics data in metabolic networks with the software Omix - a case study
-
Droste P., Miebach S., Niedenführ S., Wiechert W., Nöh K. Visualizing multi-omics data in metabolic networks with the software Omix - a case study. Biosystems 2011, 105:154-161.
-
(2011)
Biosystems
, vol.105
, pp. 154-161
-
-
Droste, P.1
Miebach, S.2
Niedenführ, S.3
Wiechert, W.4
Nöh, K.5
-
52
-
-
34547816155
-
Metabolic network visualization eliminating node redundance and preserving metabolic pathways
-
Bourqui R., Cottret L., Lacroix V., Auber D., Mary P., Sagot M.F., et al. Metabolic network visualization eliminating node redundance and preserving metabolic pathways. BMC Systems Biology 2007, 1:1-19.
-
(2007)
BMC Systems Biology
, vol.1
, pp. 1-19
-
-
Bourqui, R.1
Cottret, L.2
Lacroix, V.3
Auber, D.4
Mary, P.5
Sagot, M.F.6
-
53
-
-
77953887264
-
Arcadia: a visualization tool for metabolic pathways
-
Villéger A.C., Pettifer S.R., Kell D.B. Arcadia: a visualization tool for metabolic pathways. Bioinformatics 2010, 26:1470-1471.
-
(2010)
Bioinformatics
, vol.26
, pp. 1470-1471
-
-
Villéger, A.C.1
Pettifer, S.R.2
Kell, D.B.3
-
54
-
-
1642457253
-
The effects of alternate optimal solutions in constraint-based genome-scale metabolic models
-
Mahadevan R., Schilling C.H. The effects of alternate optimal solutions in constraint-based genome-scale metabolic models. Metabolic Engineering 2003, 5:264-276.
-
(2003)
Metabolic Engineering
, vol.5
, pp. 264-276
-
-
Mahadevan, R.1
Schilling, C.H.2
-
55
-
-
3342925846
-
Comparison of network-based pathway analysis methods
-
Papin J.A., Stelling J., Price N.D., Klamt S., Schuster S., Palsson B.Ø. Comparison of network-based pathway analysis methods. Trends in Biotechnology 2004, 22:400-405.
-
(2004)
Trends in Biotechnology
, vol.22
, pp. 400-405
-
-
Papin, J.A.1
Stelling, J.2
Price, N.D.3
Klamt, S.4
Schuster, S.5
Palsson, B.Ø.6
-
56
-
-
65549092780
-
Use of randomized sampling for analysis of metabolic networks
-
Schellenberger J., Palsson B.Ø. Use of randomized sampling for analysis of metabolic networks. Journal of Biological Chemistry 2009, 284:5457-5461.
-
(2009)
Journal of Biological Chemistry
, vol.284
, pp. 5457-5461
-
-
Schellenberger, J.1
Palsson, B.Ø.2
-
57
-
-
80052580351
-
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
-
Frezza C., Zheng L., Folger O., Rajagopalan K.N., MacKenzie E.D., Jerby L., et al. Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase. Nature 2011, 477:225-228.
-
(2011)
Nature
, vol.477
, pp. 225-228
-
-
Frezza, C.1
Zheng, L.2
Folger, O.3
Rajagopalan, K.N.4
MacKenzie, E.D.5
Jerby, L.6
-
58
-
-
79959621970
-
Predicting selective drug targets in cancer through metabolic networks
-
Folger O., Jerby L., Frezza C., Gottlieb E., Ruppin E., Shlomi T. Predicting selective drug targets in cancer through metabolic networks. Molecular Systems Biology 2011, 7:501.
-
(2011)
Molecular Systems Biology
, vol.7
, pp. 501
-
-
Folger, O.1
Jerby, L.2
Frezza, C.3
Gottlieb, E.4
Ruppin, E.5
Shlomi, T.6
-
59
-
-
77957556494
-
Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines
-
Li L., Zhou X., Ching W.K., Wang P. Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines. BMC Bioinformatics 2010, 11:501.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 501
-
-
Li, L.1
Zhou, X.2
Ching, W.K.3
Wang, P.4
-
60
-
-
0034741983
-
13C metabolic flux analysis
-
Wiechert W. 13C metabolic flux analysis. Metabolic Engineering 2001, 3:195-206.
-
(2001)
Metabolic Engineering
, vol.3
, pp. 195-206
-
-
Wiechert, W.1
-
61
-
-
79551508527
-
13C metabolic flux analysis in complex systems
-
Zamboni N. 13C metabolic flux analysis in complex systems. Current Opinion in Biotechnology 2011, 22:103-108.
-
(2011)
Current Opinion in Biotechnology
, vol.22
, pp. 103-108
-
-
Zamboni, N.1
-
62
-
-
66749182798
-
13C-based metabolic flux analysis
-
Zamboni N., Fendt S.M., Rühl M., Sauer U. 13C-based metabolic flux analysis. Nature Protocols 2009, 4:878-892.
-
(2009)
Nature Protocols
, vol.4
, pp. 878-892
-
-
Zamboni, N.1
Fendt, S.M.2
Rühl, M.3
Sauer, U.4
-
63
-
-
70449519259
-
Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells
-
Metallo C.M., Walther J.L., Stephanopoulos G. Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells. Journal of Biotechnology 2009, 144:167-174.
-
(2009)
Journal of Biotechnology
, vol.144
, pp. 167-174
-
-
Metallo, C.M.1
Walther, J.L.2
Stephanopoulos, G.3
-
64
-
-
80555149221
-
Dynamic metabolic flux analysis (DMFA): a framework for determining fluxes at metabolic non-steady state
-
Leighty R.W., Antoniewicz M.R. Dynamic metabolic flux analysis (DMFA): a framework for determining fluxes at metabolic non-steady state. Metabolic Engineering 2011, 13:745-755.
-
(2011)
Metabolic Engineering
, vol.13
, pp. 745-755
-
-
Leighty, R.W.1
Antoniewicz, M.R.2
-
65
-
-
79951999565
-
MBRole: enrichment analysis of metabolomic data
-
Chagoyen M., Pazos F. MBRole: enrichment analysis of metabolomic data. Bioinformatics 2011, 27:730-731.
-
(2011)
Bioinformatics
, vol.27
, pp. 730-731
-
-
Chagoyen, M.1
Pazos, F.2
-
66
-
-
84864479791
-
MetaboAnalyst 2.0 - a comprehensive server for metabolomic data analysis
-
Xia J., Mandal R., Sinelnikov I.V., Broadhurst D., Wishart D.S. MetaboAnalyst 2.0 - a comprehensive server for metabolomic data analysis. Nucleic Acids Research 2012, 40(Web Server issue):W127-W133.
-
(2012)
Nucleic Acids Research
, vol.40
, Issue.WEB SERVER ISSUE
-
-
Xia, J.1
Mandal, R.2
Sinelnikov, I.V.3
Broadhurst, D.4
Wishart, D.S.5
-
67
-
-
84866123900
-
An accelerated workflow for untargeted metabolomics using the METLIN database
-
Tautenhahn R., Cho K., Uritboonthai W., Zhu Z., Patti G.J., Siuzdak G. An accelerated workflow for untargeted metabolomics using the METLIN database. Nature Biotechnology 2012, 30:826-828.
-
(2012)
Nature Biotechnology
, vol.30
, pp. 826-828
-
-
Tautenhahn, R.1
Cho, K.2
Uritboonthai, W.3
Zhu, Z.4
Patti, G.J.5
Siuzdak, G.6
-
68
-
-
77954439868
-
MassBank: a public repository for sharing mass spectral data for life sciences
-
Horai H., Arita M., Kanaya S., Nihei Y., Ikeda T., Suwa K., et al. MassBank: a public repository for sharing mass spectral data for life sciences. Journal of Mass Spectrometry 2010, 45:703-714.
-
(2010)
Journal of Mass Spectrometry
, vol.45
, pp. 703-714
-
-
Horai, H.1
Arita, M.2
Kanaya, S.3
Nihei, Y.4
Ikeda, T.5
Suwa, K.6
-
69
-
-
84876148784
-
HMDB 3.0 - the human metabolome database in 2013
-
Wishart D.S., Jewison T., Guo A.C., Wilson M., Knox C., Liu Y., et al. HMDB 3.0 - the human metabolome database in 2013. Nucleic Acids Research 2013, 41(Database issue):D801-D807.
-
(2013)
Nucleic Acids Research
, vol.41
, Issue.DATABASE ISSUE
-
-
Wishart, D.S.1
Jewison, T.2
Guo, A.C.3
Wilson, M.4
Knox, C.5
Liu, Y.6
-
70
-
-
84871433609
-
Global profiling strategies for mapping dysregulated metabolic pathways in cancer
-
Benjamin D.I., Cravatt B.F., Nomura D.K. Global profiling strategies for mapping dysregulated metabolic pathways in cancer. Cell Metabolism 2012, 16:565-577.
-
(2012)
Cell Metabolism
, vol.16
, pp. 565-577
-
-
Benjamin, D.I.1
Cravatt, B.F.2
Nomura, D.K.3
-
71
-
-
78650682939
-
Isocitrate dehydrogenase-1 mutations: a fundamentally new understanding of diffuse glioma?
-
Kloosterhof N.K., Bralten L.B., Dubbink H.J., French P.J., van den Bent M.J. Isocitrate dehydrogenase-1 mutations: a fundamentally new understanding of diffuse glioma?. Lancet Oncology 2011, 12:83-91.
-
(2011)
Lancet Oncology
, vol.12
, pp. 83-91
-
-
Kloosterhof, N.K.1
Bralten, L.B.2
Dubbink, H.J.3
French, P.J.4
van den Bent, M.J.5
-
72
-
-
84855987831
-
Reductive carboxylation supports growth in tumour cells with defective mitochondria
-
Mullen A.R., Wheaton W.W., Jin E.S., Chen P.H., Sullivan L.B., Cheng T., et al. Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature 2011, 481:385-388.
-
(2011)
Nature
, vol.481
, pp. 385-388
-
-
Mullen, A.R.1
Wheaton, W.W.2
Jin, E.S.3
Chen, P.H.4
Sullivan, L.B.5
Cheng, T.6
-
73
-
-
80052258995
-
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
-
Locasale J.W., Grassian A.R., Melman T., Lyssiotis C.A., Mattaini K.R., Bass A.J., et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nature Genetics 2011, 43:869-874.
-
(2011)
Nature Genetics
, vol.43
, pp. 869-874
-
-
Locasale, J.W.1
Grassian, A.R.2
Melman, T.3
Lyssiotis, C.A.4
Mattaini, K.R.5
Bass, A.J.6
-
74
-
-
80051923932
-
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
-
Possemato R., Marks K.M., Shaul Y.D., Pacold M.E., Kim D., Birsoy K., et al. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature 2011, 476:346-350.
-
(2011)
Nature
, vol.476
, pp. 346-350
-
-
Possemato, R.1
Marks, K.M.2
Shaul, Y.D.3
Pacold, M.E.4
Kim, D.5
Birsoy, K.6
-
75
-
-
79957774646
-
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells
-
Cheng T., Sudderth J., Yang C., Mullen A.R., Jin E.S., Matés J.M., et al. Pyruvate carboxylase is required for glutamine-independent growth of tumor cells. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:8674-8679.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 8674-8679
-
-
Cheng, T.1
Sudderth, J.2
Yang, C.3
Mullen, A.R.4
Jin, E.S.5
Matés, J.M.6
|